Head of Translational Bioinformatics
Job Details
permanent
Cambridge, Eastern, United Kingdom
Talenture Group
23.04.2024
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Full Job Description
- Lead on bioinformatics,
biostatistics and visualisation programmes
- Develop
innovative strategies for target discovery / biomarker discovery
programmes, including assessment, benchmarking and theoretical
development of statistical algorithms and methodology, as well as
contribute to efficient computational implementations.
- Contribute and oversee scientific design both for technology
development and biological insight end-points
- Produce
professional reporting outputs for internal research and external
collaborations.
- Work across teams and proactively
engage in knowledge sharing and peer support, including training
- Line management
Requirements
- Track record of research in bioinformatics, biostatistics,
genomics
- Experience and strong knowledge of Machine
Learning / Deep Learning, SciML (Scientific Machine Learning)
- Excellent knowledge of two of Julia, Python and R.
Proficient with common data science libraries/toolkits such as Julia
data science libraries, Pandas, SciKit-Learn, Numpy, Keras etc.
- Experience with Next Generation Sequencing platforms and /
or OMICS datasets
- Familiarity with common bioinformatic
databases and tools
- Knowledge of version control and
collaborating with developers using GitHub
- Excellent
oral and written communication skills
- Excellent
organizational and record keeping skills
- Programming
and statistical data analysis and visualisation experience in R or
Python with one or more common ML frameworks (Tensorflow, PyTorch,
etc…)
- Experience with variant calling, exome/WGS
pipelines or other high-throughput genomics workflows
- Good knowledge of biomarker discovery / target discovery
- Ability to deliver quick wins alongside implementing more
advanced modelling techniques
- Line management
experience
Desired Qualifications
and Experience
- Experience with and understanding of Hi-C, capture
Hi-C, HiChIP
- A social personality that contributes to
an open, positive, collaborative working climate, and a strong desire
to drive personal development
- Proven experience of
working in a fast-paced research-driven commercial environment or in
collaboration with industry
- A strategic, inquisitive
and innovative mindset with the ability to sense commercial
opportunities in our data and exploit accordingly
- Delivery skills with the ability to work well under pressure in an
agile environment
- Experience with pipeline development
and software virtualisation (e.g. docker, singularity)