What Senior Immunoassay Scientist Jobs are in the United Kingdom?

Insmed Incorporated is seeking a Senior Scientist specializing in immunoassay development at their Babraham site in the UK. The successful candidate will lead the design and implementation of cutting-edge immunoassays to support drug discovery, work collaboratively with interdisciplinary teams, and mentor junior scientists in assay techniques.

This role offers a hybrid working model and revolves around a commitment to advancing therapeutics in a supportive and innovative environment.

VRS-UK is seeking an experienced, personable and analytically minded Scientist to drive antibody and immunoassay development with career progression in an internationally renowned biopharmaceutical laboratory.

You will develop, validate and troubleshoot immunoassays to support PK, PD, ADA and biomarker studies, ensuring delivery to the highest scientific and regulatory standards, and act as a scientific contact for internal teams and external clients.

At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as Science magazine’s No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK.

For patients, for each other, and for the future of science, we’re in. Are you?

We are seeking a highly experienced, industry-trained Senior Scientist specialising in immunoassay development to join our evolving drug discovery team at Insmed Cambridge. This is an exciting, lab-based opportunity for an innovative and motivated assay scientist with deep expertise in novel immunoassay design, supporting a wide range of projects in our portfolio.

Operating within our Drug Discovery Biology team and sitting within the Compound Profiling group, you will be accountable for designing, implementing, and delivering robust immunoassay data to support screening cascades that enable the progression of small molecule and oligonucleotide therapeutics from early target feasibility and Hit Finding, through to Candidate Nomination.

You will act as our core subject matter expert for immunoassays, taking ownership of experimental design and data generation. Applying a rigorous, industry-standard approach, you will develop novel, highly sensitive assays to deliver high-quality, reproducible bioanalytical data that informs project progression. You will collaborate closely with interdisciplinary teams to translate new biological insights into life-changing therapeutics.

• Collaboratively design, implement, and interpret immunoassay data as part of screening cascades to advance drug discovery programs.
• Perform hands-on development, optimisation, validation, and troubleshooting of highly sensitive singleplex and multiplex immunoassay formats (e.g., ELISA, HTRF, AlphaLISA, MSD, Luminex) to assess target engagement, pathway modulation, and mechanism-of-action.
• Apply strong pharmacological expertise and early-stage, fit-for-purpose method validation principles to optimise assay performance parameters to generate robust, decision-enabling pharmacodynamic and target engagement data.
• Generate high-quality data to characterise novel small molecule and oligonucleotide therapeutics, informing structure-activity relationships and compound progression criteria.
• Support early pharmacokinetic, pharmacodynamic, and immunogenicity assessments to drive Lead Optimisation and candidate selection.
• As part of the Compound Profiling Team, maintain the flexibility to run broader in vitro compound profiling assays (e.g., standard biochemical or cellular screens) to support the team\'s overall screening cascades and workload.
• Oversee data generation conducted at external vendors/CROs via scientific monitoring, critically appraising scientific quality, data interpretation, and timely delivery.

• Contribute to a high-performing Compound Profiling team, acting as the core subject matter expert for immunoassays and drug discovery cascade target engagement and pharmacodynamic marker data across the early Discovery portfolio.
• Provide broad, hands-on support for general compound profiling activities to drive DMTA cycles, partnering with Chemistry, DMPK, and project teams to ensure assays align with project milestones and accelerate informed compound progression.
• Support, mentor, and develop junior scientists in immunoassay techniques and troubleshooting (with the potential for formal line management responsibilities depending on experience), promoting professional growth, knowledge-sharing, and a collaborative laboratory culture.

• Continuously enhance in-house experimental capabilities by proactively identifying, evaluating, and adopting innovative solutions and emerging immunoassay technology platforms (e.g., automated liquid handling, ultra-sensitive detection platforms), depending on project needs.
• Contribute to further strengthening our research infrastructure and technological platforms, supporting assay scalability, throughput, and long-term project successes.

• Perform in-depth reviews and critical appraisal of scientific literature and internal data to inform analyte selection and assay strategy.
• Work closely with our Target Discovery and New Project teams to evaluate novel targets, assess biological tractability, and design bespoke, innovative immunoassay solutions that directly underpin drug discovery and screening cascades.

• Analyse, interpret, and present high-quality data packages and reports at Project and Biology meetings to support informed matrix-driven decision-making and advance project milestones.
• Integrate learnings from disease biology and in vivo pharmacology teams into assay strategy, ensuring in vitro to in vivo alignment to support PK/PD modelling and dose-response evaluation.

• Follow, develop, review, and maintain SOPs for immunoassay protocols, instrumentation, and laboratory workflows, ensuring compliance with health and safety regulations.
• Accurately record experimental data using electronic lab notebooks (ELNs) and use industry-standard data analysis and management software to support high-quality, reproducible research.

• Degree coupled with extensive immunoassay or early-stage target engagement/pharmacodynamic assay development experience for small molecule (and ideally oligonucleotide) projects within a drug discovery environment; it is typical at this level that you would have at least 5 years’ relevant experience.
• Proven track record in designing, developing, executing, troubleshooting, and interpreting a broad range of highly sensitive singleplex and multiplex immunoassays (e.g., ELISA, HTRF, AlphaLISA, MSD, Luminex), applying fit-for-purpose method validation principles to rigorously assess target engagement, pathway modulation, and pharmacodynamic analytes.
• Demonstrated experience contributing to DMTA cycles and working in close partnership with Chemistry, DMPK, and broader multidisciplinary teams.
• Experience managing and collaborating with CROs, including oversight of immunoassay data generation, cascade biomarker assay development, and compound logistics/management workflows.
• Working knowledge of standard assay automation (e.g., liquid handling and plate-based workflows), data analysis tools (e.g., GraphPad Prism), ELNs, and scientific databases to support bioanalyte assay development and profiling is essential.
• Strong verbal and written communication skills, with the ability to clearly convey complex scientific concepts to diverse audiences.
• Excellent analytical thinking and numerical proficiency.
• Up-to-date awareness of latest technological developments in immunoassay platforms, biomarker detection, and pharmacology.
• Candidates with practical or applied experience with ultra-sensitive platforms (e.g., Simoa), cellular profiling techniques (e.g., flow cytometry, high-content imaging), or evaluating novel modalities such as oligonucleotides would be highly desirable.
• Experience with broader in vitro assay development (e.g., standard biochemical, cellular, or biophysical techniques) is highly desirable, reflecting the flexibility and willingness to support the team’s general compound profiling workload when required.
• Prior experience in mentoring and developing junior scientists is essential, while formal line management experience is advantageous.

This role will require you to work from our brand-new state-of-the-art offices and labs situated in Babraham Research Campus, South Cambridge. Hybrid working is offered based on specific business needs and the role requirements.

Our research site in Cambridge, UK is situated in brand new labs and offices at the Babraham Research Campus—a leading hub for bioscience innovation and collaboration. Our team of biologists, human geneticists, bioinformaticians, data scientists, computational and synthetic chemists bring together a wide range of technologies and modalities to deliver powerful new ways of treating serious diseases.

At Insmed, you’ll find a culture as human as our mission—intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself.

• Competitive retirement benefits, global equity awards, and participation in our Employee Stock Purchase Plan (ESPP)
• Career development through the Insmed Learning Institute, external programs, LinkedIn Learning, and role-specific training
• AI-powered and on-demand learning tools, including a digital assistant to help navigate internal resources
• Hybrid-friendly technology and IT support for seamless teamwork across locations and time zones
• Global recognition programs and Employee Resource Groups
• Eligibility for specific programs may vary and is subject to the terms and conditions of each plan

Kids for the Future is seeking a Principal Scientist in Fordham to provide scientific leadership and oversee technical aspects within the immunoassay group. You will drive method development and oversee project quality while mentoring a team of scientists.

The role requires deep expertise in bioanalytical methods and a strong track record in GxP compliance. You will lead initiatives, fostering innovation and collaboration while building robust client relationships.

This position offers an opportunity to significantly impact scientific practices and contribute to continuous improvement in bioanalysis.

Moderna in Harwell is seeking an Associate Director, Immuno‑assay UK to lead cell-based immunoassay development for clinical programs. You will guide qualification, validation, data generation, and reporting across multiple therapeutic areas, ensuring data integrity and regulatory compliance.

The role requires deep immunology expertise, leadership in a cross-functional team, and ongoing collaboration with external partners to advance platform capabilities and innovative workflows.

Role Overview

We are seeking a Senior Scientist II (Project Leader/Principal Investigator) – Immunoassay Bioanalysis (PK/ADA/PD)/Responsible Scientist to lead immunoanalytical studies, ensuring scientific robustness and regulatory compliance.

• Act as scientific lead for PK, ADA, and PD immunoassay studies
• Oversee assay development, validation, and sample analysis
• Evaluate assay performance and investigate variability or interference issues
• Ensure assays are fit for purpose and meet regulatory requirements
• Act as primary scientific contact for clients
• Prepare, review, and approve study documentation

• Strong experience with immunoassay platforms and assay formats
• Experience in assay development, validation, and troubleshooting
• Understanding of drug interference, variability, and assay performance

• MSc or PhD in Immunology, Biochemistry, or related field
• 5 to 10 or more years of immunoassay bioanalysis experience
• Experience leading regulated studies in a GLP/GCP environment

Overview

Exciting new opportunity for an experienced, personable and analytically minded Scientist seeking career progression with an internationally renowned and expanding Biopharmaceutical Laboratory. In this diverse, multifaceted position you will call upon your expertise in a range of ligand binding assay techniques to undertake a broad range of challenging projects for several world leading organisations. Acting as a scientific point of contact for both internal teams and external clients, your work will focus on the development, validation, and troubleshooting of immunoassays used to support PK, immunogenicity, and biomarker studies, ensuring delivery to the highest scientific and regulatory standards.

This role is centred on providing scientific leadership and oversight of all the technical aspects within the local Fordham immunoassay group, and throughout the wider Resolian immunoassay teams.

You will be responsible for providing supervision, guidance, and expertise, in order to facilitate the delivery of high quality methods and sample analysis results to our customers in compliance with GLP/GCP.

As a Principal Scientist, you are an expert in scientific technology and experimental practice with peer recognition and credibility. You have a track record of publications and presentations in support of this, which you proactively drive.

Principal Scientists should lead from the lab. They are capable of working creatively and autonomously and they possess a deep technical understanding to develop or troubleshoot methods themselves across all service areas. They demonstrate scientific leadership and clear decision making, directing the work of more junior staff, leading technical training and promotion of good scientific practices.

We are looking for someone who has an innate ability to adopt and adapt new technology and can be an active contributor to the company’s Scientific Strategy. You will also be creative, innovative, agile and collegiate. This means they also promote scientific collaboration, knowledge sharing, and best practice across all Resolian sites; they often explore opportunities to create new service lines or scientific IP, and they can possess expertise that cuts across multiple departments.

Principal Scientists are highly visible and outward interfacing, they are the scientific facade of Resolian, and they use their skills and expertise to advise customers and drive new business.

Confidence in regular effective external communication is expected, as is deputising for senior management. This also includes assisting with presentations to new customers and participation in global capability meetings, and directing technical input for new RFP/RFIs. Externally, they will build a professional reputation at both personal and corporate levels, through regular podium presentations at key bioanalytical conferences. They are always forward-looking, and ready to be vocal to challenge the status quo if they see a better solution.

• Provide oversight of active method development projects in the Immunoassay Bioanalysis group, ensure projects are progressing to client expectations
• Lead challenging method development projects, using expert knowledge to deliver quality methods on-time
• Drive the method development strategy, ensuring methods are developed efficiently, and are robust, fit-for-purpose and compliant. Defend these decisions under regulatory scrutiny.
• Mentor scientists working on method development projects; providing scientific guidance and support
• Provide troubleshooting expertise across multiple methods and platforms
• Review and interpret method trending data and drive improvements as appropriate
• Review method establishment and method validation data ensuring methods are of good quality before they progress to the next stage
• Deliver scientific training within the group and present internally on best practices
• Have a good knowledge of the appropriate GLP / GCP standards and latest regulatory guidelines and industry thought leaders.
• Provide scientific support to the Business Development team; review customer requests and advise on feasibility
• Contribute to a culture of continuous improvement
• Build and maintain good working relationships with internal and external clients, management and other scientific staff
• Familiarity with the financial aspects of projects including time and materials costs

• Degree in pharmaceutical sciences, biochemistry, chemistry, biological sciences, or equivalent industry experience in bioanalysis.
• Extensive experience leading the development, validation, and application of ligand-binding assays to support PK, biomarker, and immunogenicity (ADA and NAb) studies across preclinical and clinical programmes.
• Strong scientific judgement in selecting fit-for-purpose bioanalytical platforms to meet sponsor requirements and regulatory expectations.
• Proven experience operating within a GxP-regulated CRO environment.
• In-depth knowledge of global regulatory guidance and industry best practice for bioanalytical method validation of PK, biomarker, and immunogenicity assays.
• Demonstrated scientific leadership, including mentoring scientists, setting bioanalytical strategy, and collaborating effectively with cross-functional teams.