40 Director Of Drug Safety jobs in the United Kingdom

CPL Life Sciences are in collaboration with a world-renowned global pharmaceutical company who are seeking two new professionals at varying experience levels to join their Safety Science and Pharmacovigilance team. This role provides scientific safety oversight across the full lifecycle of investigational and marketed products.

As a Safety Scientist, you key responsibilities will include:

• Support safety activities in early and late-phase clinical development
• Conduct signal detection, evaluation, and contribute to risk-benefit assessments
• Manage individual case safety reports (ICSRs) and prepare aggregate reports (e.g., DSURs, PBRERs)
• Participate in the preparation and review of regulatory submissions (INDs, NDAs, MAAs, etc.)
• Contribute to the development and maintenance of safety labeling and core safety documents
• Collaborate with internal teams and external partners to ensure high-quality safety deliverables
• Provide safety input to study teams and participate in cross-functional meetings
• Help prepare materials for safety committees (e.g., iDMCs, IMCs) and regulatory authorities

Hybrid: North London 2 days per week on site, 3 days remote

Applicants should have direct experience working with signal detection, aggregate reports and risk management plans in particular for both clinical and post-marketing activities.

Strong analytical, communication, and collaboration skills are essential for success in this role.

Job Role Overview

Clinical Safety Officer - This opening is to join one of the foremost strategy, risk and compliance providers in the UK. We are looking for an experienced Clinical Safety Officer (CSO) to support our growing international client base.

About The AbedGraham Group

Established over a decade ago, The AbedGraham Group has grown in to one of the most trusted consultancies for technology companies and government agencies. We provide a range of strategic, marketing, project management and compliance services for health IT, security, medical device and network infrastructure vendors. Within our compliance service set, we provide DCB0129, Digital Technology Assessment Criteria (DTAC), Data Security and Protection toolkit (DSPT) and cybersecurity services for dozens of the industry’s leading companies.

About the Job

The job role is to join the compliance team at The AbedGraham Group in the capacity of Clinical Safety Officer. Within the NHS, all suppliers of digital technologies that impact patient care are obliged to comply with the mandatory DCB0129 standard and complete DTAC submissions for review by purchasing organisations or regulators. The AbedGraham Group assists dozens of companies with these processes and frequently acts as the Clinical Safety Officer on their behalf. You will be working under the COO to help maintain existing clients’ compliance and ensuring new clients’ requirements are met. Our compliance work extends across a huge range of specialties from primary to secondary to community and mental health care and across dozens of healthcare IT verticals including EHR, document management, radiology, psychiatry, remote monitoring, online and video consultations, community testing, speech recognition and digital dictation, genomics and surgery.

Essential Requirements

• A registered clinician with a UK professional body with at least 2 years’ experience
• An approved Clinical Safety Officer (that is either evidence of NHS Digital’s risk course attendance or a similar accreditation)
• At least 2 years’ experience in either creating or reviewing the standard documents within DCB0129 (clinical safety case report, hazard log, clinical risk management plan/system)
• Knowledge of clinical informatics and its application in multiple healthcare environments
• Knowledge of ongoing compliance requirements (software testing, release reviews, incident management)
• Exceptional communication and documentation skills
• Exceptional productivity and efficiency

Desirable Requirements

• Experience with companies who have Artificial Intelligence (AI) as part of their product set
• Knowledge or experience of medical device regulations including ISO13485 and ISO14971
• Knowledge or experience of deploying healthcare technologies in line with DCB0160 best principles
• Knowledge of wider DTAC competencies (security, data protection, interoperability)
• Experience in or working with NHS Digital or regional/national procurements/rollouts
• Experience with medical device regulation

The Offer

• Fully remote working
• Competitive Salary
• Up to 10% bonus annually
• Private healthcare cover
• Company pension
• All professional training/accreditation requirements and costs covered
• All IT requirements and costs covered

Finally the opportunity for job growth is important to us. The right candidate can expect the responsibility of managing our clients’ work themselves as well as overseeing the work of others in due course. A more strategic role, reporting to the executive board, will also be considered after 12 months. Please send all submissions and CVs to , we look forward to speaking with you and for you to join us on this exciting journey!

• Develop and implement comprehensive medical affairs strategies aligned with the company's objectives and therapeutic area focus.
• Build and maintain strong relationships with Key Opinion Leaders (KOLs), investigators, and other relevant stakeholders in the medical community.
• Oversee the generation and dissemination of scientific and clinical data through various channels, including publications, presentations, and advisory boards.
• Ensure compliance with all relevant industry regulations, codes of conduct, and company policies.
• Collaborate closely with cross-functional teams, including R&D, marketing, regulatory affairs, and commercial.
• Provide scientific and medical expertise to support product development, market access, and commercial initiatives.
• Organize and lead medical education programs and scientific exchange activities.
• Contribute to the development of medical information and communication materials.
• Manage the medical affairs budget for assigned projects and therapeutic areas.
• Stay abreast of the latest scientific advancements, clinical trial outcomes, and market trends.
• Identify opportunities for research collaborations and investigator-initiated studies.
• Train and mentor junior members of the medical affairs team.

• Medical degree (MD, DO, MBBS) or Ph.D. in a relevant life sciences discipline.
• Minimum of 7 years of progressive experience in Medical Affairs within the pharmaceutical industry.
• Proven track record in developing and executing successful medical affairs strategies.
• In-depth understanding of clinical development, regulatory affairs, and market access.
• Strong knowledge of the relevant therapeutic area (e.g., Oncology, Cardiology, Neurology).
• Exceptional communication, presentation, and interpersonal skills, with the ability to engage effectively with diverse audiences.
• Demonstrated ability to build and maintain strong relationships with KOLs.
• Excellent analytical and strategic thinking capabilities.
• Experience in managing budgets and cross-functional projects.
• Ability to work independently and collaboratively in a fully remote setting.
• Fluency in English; additional languages may be an asset.

• Develop and execute comprehensive medical affairs strategies aligned with product life cycle and business objectives.
• Identify, profile, and engage with Key Opinion Leaders (KOLs), medical experts, and investigators.
• Develop and deliver scientific and medical information to internal and external stakeholders.
• Oversee the planning and execution of medical education programs, symposia, and advisory boards.
• Review and approve promotional and non-promotional materials to ensure scientific accuracy and compliance with regulatory standards.
• Contribute to the development of clinical trial protocols and study designs.
• Analyze and interpret complex clinical data, providing medical insights and recommendations.
• Collaborate closely with R&D, marketing, regulatory affairs, and other cross-functional teams.
• Manage the medical affairs budget and resources effectively.
• Stay abreast of the latest scientific literature, clinical advancements, and market trends within relevant therapeutic areas.
• Ensure compliance with all applicable industry codes, regulations, and company policies.
• Mentor and guide junior medical affairs professionals.

• Advanced scientific degree (MD, PharmD, PhD) in a relevant discipline.
• Minimum of 7-10 years of experience in medical affairs within the pharmaceutical industry, with a strong focus on medical strategy.
• Proven experience in developing and implementing successful medical affairs plans.
• Extensive knowledge of clinical research, data interpretation, and regulatory requirements.
• Demonstrated ability to engage effectively with KOLs and scientific communities.
• Excellent strategic thinking, analytical, and problem-solving skills.
• Exceptional written and verbal communication and presentation skills.
• Proven ability to manage multiple projects in a fast-paced, remote environment.
• Strong understanding of pharmacovigilance and compliance requirements.
• Ability to travel domestically and internationally as required.

Account Manager / Senior Account Manager / Account Director – Medical Affairs (Remote, UK)

Remote (UK-based) | Full-time

We’re looking for talented client services professionals to join a fast-growing Medical Affairs communications team . Whether you’re an Account Manager, Senior Account Manager or Account Director , this is an opportunity to shape and deliver impactful scientific communications that help transform healthcare.

What you’ll be doing

• Acting as a trusted partner to clients, with a deep understanding of their goals, priorities and challenges.
• Taking ownership of accounts and projects end-to-end — from planning and resourcing through to delivery, financial management and forecasting.
• Leading on client relationships, ensuring expectations are not just met but exceeded.
• Driving collaboration across internal teams, supporting colleagues and fostering a culture of togetherness.
• Contributing to strategic thinking while keeping execution organised, efficient and of the highest quality.

What we’re looking for

• A science-related degree (or equivalent experience).
• Proven experience in a medical communications agency , ideally stepping up from SAE > AM, or already operating at SAM / AD level.
• Ability to manage multiple projects with precision and attention to detail.
• A proactive, solutions-focused mindset with excellent written and verbal communication skills.
• A team player who thrives in a collaborative, fast-paced environment.

What’s on offer

• Competitive salary + bonus scheme
• Private healthcare
• Hybrid/remote working (with access to a central London co-working space if desired)
• 24 days’ holiday + bank holidays, plus office closure over Christmas
• Regular team socials and events

If you’re passionate about bringing science to life through meaningful Medical Affairs communications , and ready to take the next step in your agency career, we’d love to hear from you.