7,358 Drug Development jobs in the United Kingdom
Principal Scientist - Drug Discovery & Development
MK9 2EB Milton Keynes, South East
£70000 Annually
WhatJobs
Posted 9 days ago
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Job Description
Our client, a pioneering biotechnology company at the forefront of therapeutic innovation, is seeking a highly accomplished Principal Scientist to lead critical research initiatives within their Drug Discovery & Development division. Based in Milton Keynes, Buckinghamshire, UK , this role is integral to advancing novel treatment modalities from early-stage research through to preclinical development. The successful candidate will bring a wealth of scientific expertise, a proven track record in research leadership, and a passion for translating scientific breakthroughs into life-changing medicines. This is a lab-based role requiring hands-on involvement and direct oversight of research activities.
Key Responsibilities:
Key Responsibilities:
- Design, execute, and interpret complex experiments to drive drug discovery programmes forward.
- Lead and mentor a team of talented research scientists and technicians, fostering a culture of scientific excellence and collaboration.
- Develop and validate novel assays and technologies to support drug discovery efforts.
- Identify and evaluate promising therapeutic targets and lead compounds.
- Oversee preclinical studies, including in vitro and in vivo models, to assess compound efficacy and safety.
- Collaborate effectively with cross-functional teams, including chemistry, pharmacology, toxicology, and translational science.
- Author high-quality scientific reports, manuscripts, and patent applications.
- Present research findings at internal meetings and external scientific conferences.
- Manage external collaborations with academic institutions and contract research organizations (CROs).
- Contribute to strategic planning for the R&D pipeline and portfolio management.
- Ensure compliance with all relevant laboratory safety regulations and best practices.
- Stay abreast of the latest scientific advancements and competitive landscape in relevant therapeutic areas.
- Ph.D. in Pharmacology, Molecular Biology, Biochemistry, Immunology, or a related life science discipline.
- Minimum of 10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry, with a strong focus on drug discovery.
- Demonstrated leadership experience in managing scientific teams and projects.
- Deep expertise in (Specific therapeutic area relevant to fictional company, e.g., oncology, infectious diseases, neuroscience) and associated drug discovery methodologies.
- Proficiency in a wide range of in vitro and in vivo experimental techniques.
- Proven ability to design and execute complex research strategies and troubleshoot effectively.
- Excellent analytical, problem-solving, and critical thinking skills.
- Exceptional written and verbal communication skills, with a track record of publications and presentations.
- Experience with biostatistics and data analysis software.
- Strong project management skills and the ability to manage multiple priorities.
- A passion for scientific innovation and a commitment to developing novel therapeutics.
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0
Principal Scientist - Drug Discovery & Development
G2 1EU Glasgow, Scotland
£80000 Annually
WhatJobs
Posted 14 days ago
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Job Description
Our client, a renowned pharmaceutical research and development company located in Glasgow, Scotland, UK , is seeking a highly accomplished Principal Scientist to lead critical initiatives in drug discovery and development. This senior role is responsible for driving innovation, designing experimental strategies, and executing complex research projects aimed at identifying and advancing novel therapeutic candidates. You will play a key part in shaping the company's R&D pipeline, leveraging your deep scientific expertise to overcome research challenges and accelerate the progression of drug candidates through preclinical and early clinical stages. The ideal candidate will possess a strong track record in medicinal chemistry, pharmacology, or a related discipline, with a comprehensive understanding of the drug discovery process from target identification to candidate selection. Proven experience in leading scientific teams, managing research projects, and mentoring junior scientists is essential. You must demonstrate excellent analytical and problem-solving skills, with the ability to interpret complex data, draw insightful conclusions, and make critical research decisions. Strong communication and presentation skills are required to effectively convey scientific findings to internal stakeholders, including senior management and cross-functional teams, as well as external collaborators. Proficiency with relevant laboratory techniques, data analysis software, and scientific literature databases is expected. This hybrid position offers the benefit of collaborative laboratory work and team meetings, combined with the flexibility of focused remote work. We are looking for a visionary scientific leader with a passion for innovation and a commitment to developing life-changing medicines. A Ph.D. in a relevant scientific field (e.g., Pharmacology, Medicinal Chemistry, Biochemistry) and a minimum of 10 years of progressive experience in the pharmaceutical industry are required. Join our esteemed team in Glasgow and make a significant impact on global health.
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Principal Scientist - Drug Discovery & Development
ST1 5NB Staffordshire, West Midlands
£75000 Annually
WhatJobs
Posted 14 days ago
Job Viewed
Job Description
Our client, a rapidly growing pharmaceutical company dedicated to discovering and developing life-changing medicines, is seeking a highly accomplished Principal Scientist to join their remote-first research team. This pivotal role is essential for driving innovation in drug discovery and development. You will leverage your deep scientific expertise to design and execute complex research projects, mentor junior scientists, and contribute to strategic decision-making. This is an exceptional opportunity to make a tangible impact on patient lives from the comfort of your home office.
Key Responsibilities:
Key Responsibilities:
- Lead and execute complex research projects focused on novel therapeutic targets and drug candidates.
- Design and implement in vitro and in vivo experimental studies to assess drug efficacy, safety, and pharmacokinetics.
- Analyze and interpret complex biological data, drawing insightful conclusions and proposing next steps.
- Develop and validate new assays and methodologies to support drug discovery programs.
- Collaborate effectively with internal teams (chemistry, biology, DMPK) and external partners to advance pipeline projects.
- Provide scientific leadership and mentorship to junior scientists and research associates.
- Stay at the forefront of scientific literature, identifying emerging trends and opportunities in pharmaceutical research.
- Prepare high-quality scientific reports, presentations, and manuscripts for internal and external dissemination.
- Contribute to the strategic direction of the company's research pipeline and portfolio.
- PhD in Molecular Biology, Pharmacology, Biochemistry, or a related life science discipline.
- 10+ years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
- Proven track record of successfully leading drug discovery projects from target identification through preclinical development.
- Extensive experience with various biological assays, molecular biology techniques, and cell-based models.
- Strong understanding of immunology, oncology, or other relevant therapeutic areas.
- Demonstrated ability to design, execute, and interpret complex experiments.
- Exceptional critical thinking, problem-solving, and analytical skills.
- Excellent written and verbal communication skills, with a talent for presenting complex scientific information.
- Experience mentoring and managing scientific staff is essential.
This advertiser has chosen not to accept applicants from your region.
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Principal Scientist - Drug Discovery & Development
BD3 0HF Bradford, Yorkshire and the Humber
£75000 Annually
WhatJobs
Posted 24 days ago
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Job Description
Our client is a leading pharmaceutical innovator seeking a highly accomplished Principal Scientist to drive critical drug discovery and development initiatives within their state-of-the-art research facility located in **Bradford, West Yorkshire, UK**. This pivotal role involves leading complex research projects, from target identification and validation through to preclinical development, contributing significantly to the company's pipeline of novel therapeutics. You will leverage your deep scientific expertise and extensive experience to guide research strategies, foster innovation, and ensure the efficient progression of drug candidates.
Key Responsibilities:
Key Responsibilities:
- Lead and manage multiple drug discovery projects from concept to preclinical candidate selection.
- Design and execute complex biological experiments to investigate disease mechanisms and identify novel therapeutic targets.
- Develop and optimize assay development strategies for high-throughput screening and compound characterization.
- Analyze and interpret experimental data, making critical decisions on project direction and go/no-go criteria.
- Collaborate closely with internal teams (e.g., medicinal chemistry, pharmacology, DMPK) and external partners to advance drug candidates.
- Stay current with scientific literature and emerging technologies in relevant therapeutic areas and drug discovery methodologies.
- Prepare and present research findings to senior management, scientific committees, and at external conferences.
- Contribute to the development of intellectual property and regulatory submissions.
- Mentor and guide junior scientists, fostering a culture of scientific excellence and collaboration.
- Ensure compliance with all relevant safety, ethical, and regulatory guidelines.
- Ph.D. in Molecular Biology, Biochemistry, Pharmacology, or a closely related life science discipline.
- A minimum of 8-10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
- Demonstrated success in leading drug discovery projects and bringing candidates into preclinical development.
- Extensive knowledge of various drug discovery platforms and modalities (e.g., small molecules, biologics).
- Proficiency in experimental design, data analysis, and interpretation using relevant software.
- Excellent understanding of relevant therapeutic areas (e.g., oncology, immunology, neuroscience).
- Strong leadership, project management, and communication skills.
- Proven ability to work effectively in a multidisciplinary, matrixed environment.
- Experience with manuscript preparation and scientific presentation is essential.
- A strong publication record in peer-reviewed journals is highly desirable.
This advertiser has chosen not to accept applicants from your region.
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Principal Pharmaceutical Scientist - Drug Discovery & Development
LS1 1AA Leeds, Yorkshire and the Humber
£80000 Annually
WhatJobs
Posted 22 days ago
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Job Description
Our client, a pioneering pharmaceutical research company, is seeking a highly accomplished Principal Pharmaceutical Scientist to lead critical initiatives within their drug discovery and development pipeline. This is a fully remote position, allowing top talent to contribute from anywhere in the UK. You will be at the forefront of identifying, characterizing, and advancing novel therapeutic candidates from early-stage research through preclinical development. Your deep scientific expertise and leadership will be instrumental in shaping the future of medicine.
As a remote-first employee, you will leverage state-of-the-art digital collaboration tools to work seamlessly with interdisciplinary teams, including chemists, biologists, pharmacologists, and regulatory affairs specialists. This role demands a strategic thinker with a proven ability to drive projects forward, overcome complex scientific challenges, and contribute to the submission of robust regulatory dossiers.This is a 100% remote role, based anywhere in the UK.
Key Responsibilities:
Qualifications:
As a remote-first employee, you will leverage state-of-the-art digital collaboration tools to work seamlessly with interdisciplinary teams, including chemists, biologists, pharmacologists, and regulatory affairs specialists. This role demands a strategic thinker with a proven ability to drive projects forward, overcome complex scientific challenges, and contribute to the submission of robust regulatory dossiers.This is a 100% remote role, based anywhere in the UK.
Key Responsibilities:
- Lead the design and execution of drug discovery and early development programs, focusing on (specific therapeutic areas, e.g., oncology, immunology, neurology).
- Develop and implement innovative strategies for hit-to-lead and lead optimization, utilizing a deep understanding of medicinal chemistry, pharmacology, and drug metabolism.
- Oversee in vitro and in vivo studies to assess the efficacy, safety, and pharmacokinetic properties of drug candidates.
- Critically evaluate experimental data, interpret results, and make data-driven decisions to guide project progression.
- Prepare high-quality scientific reports, presentations, and publications for internal review and external dissemination.
- Contribute significantly to the preparation of regulatory documents, such as Investigational New Drug (IND) applications and New Drug Applications (NDA).
- Mentor and guide junior scientists, fostering a culture of scientific excellence and collaboration.
- Manage external research collaborations and contract research organizations (CROs) effectively.
- Represent the company at scientific conferences and engage with the broader research community.
Qualifications:
- Ph.D. in Pharmacology, Medicinal Chemistry, Biochemistry, or a related life sciences discipline.
- Minimum of 8 years of progressive experience in drug discovery and development within the pharmaceutical or biotechnology industry.
- Extensive experience in (specific therapeutic area) is highly preferred.
- Demonstrated success in advancing drug candidates from discovery through preclinical development.
- Strong knowledge of drug discovery processes, including target identification, lead optimization, and ADME/Tox studies.
- Proficiency in experimental design, data analysis, and interpretation.
- Excellent written and verbal communication skills, with a track record of contributing to regulatory submissions.
- Proven leadership abilities and experience mentoring scientific staff.
- Ability to work independently and collaboratively in a remote, fast-paced research environment.
- A strong publication record in peer-reviewed journals is a significant asset.
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4
Senior Pharmaceutical Scientist - Drug Discovery & Development
L3 0BH Liverpool, North West
£65000 Annually
WhatJobs
Posted 24 days ago
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Job Description
Our client, a pioneering biopharmaceutical company, is seeking a highly skilled Senior Pharmaceutical Scientist to join their cutting-edge research and development team in **Liverpool, Merseyside, UK**. This pivotal role focuses on the discovery and development of novel therapeutic agents. You will be responsible for designing and executing experiments, analyzing complex data, and contributing to the preclinical and early clinical development of drug candidates. The ideal candidate will possess a strong scientific background in pharmacology, medicinal chemistry, or a related field, coupled with extensive experience in drug discovery methodologies. You will play a key role in project teams, driving scientific innovation and contributing to the advancement of life-saving medicines.
Key Responsibilities:
Qualifications:
Key Responsibilities:
- Design, conduct, and optimize in vitro and in vivo studies to evaluate the efficacy and safety of drug candidates.
- Develop and validate biological assays to support drug discovery and development programs.
- Analyze and interpret complex experimental data, employing statistical methods and scientific rigor.
- Contribute to the preparation of research reports, regulatory submissions, and scientific publications.
- Collaborate effectively with cross-functional teams, including medicinal chemists, pharmacologists, toxicologists, and formulation scientists.
- Stay abreast of the latest scientific advancements, literature, and technologies in pharmaceutical sciences.
- Manage research projects, including resource allocation, timeline management, and budget adherence.
- Mentor and guide junior scientists, fostering a culture of scientific excellence and continuous learning.
- Contribute to the identification and validation of novel drug targets.
- Ensure adherence to all laboratory safety protocols and Good Laboratory Practice (GLP) guidelines.
Qualifications:
- PhD in Pharmacology, Medicinal Chemistry, Biochemistry, or a related life science discipline.
- Minimum of 5 years of post-doctoral or industry experience in drug discovery and development.
- Proven track record of scientific contributions, demonstrated through publications and presentations.
- Extensive experience with a range of drug discovery techniques and methodologies.
- Strong understanding of preclinical development pathways and regulatory requirements.
- Excellent analytical, problem-solving, and critical thinking skills.
- Proficiency in data analysis software and scientific literature databases.
- Strong written and verbal communication skills.
- Ability to work independently and collaboratively within a team in **Liverpool, Merseyside, UK**.
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5
Lead Clinical Research Scientist - Oncology Drug Development
PO1 3DT Portsmouth, South East
£70000 Annually
WhatJobs
Posted 2 days ago
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Job Description
Our client, a pioneering pharmaceutical company at the forefront of innovative cancer therapies, is seeking a highly accomplished Lead Clinical Research Scientist to join their fully remote R&D team. This critical role will focus on the strategic design, execution, and analysis of clinical trials for novel oncology therapeutics. You will be instrumental in driving the drug development pipeline forward, ensuring scientific rigor and compliance with all regulatory standards. The ideal candidate will possess a PhD or equivalent in a relevant life science discipline, coupled with extensive experience in clinical trial management, data analysis, and interpretation within the oncology field. Responsibilities include developing clinical trial protocols, overseeing study conduct, collaborating with cross-functional teams (including biostatistics, data management, and regulatory affairs), and authoring clinical study reports and regulatory submissions. You will be expected to provide scientific leadership, mentor junior researchers, and stay abreast of the latest advancements in cancer biology, pharmacodynamics, and clinical trial methodologies. This position requires exceptional analytical skills, a strong understanding of statistical principles, and the ability to communicate complex scientific information effectively to both scientific and non-scientific audiences. Working in a fully remote capacity, you must demonstrate excellent organizational skills, proactivity, and the ability to manage multiple projects simultaneously while maintaining high standards of quality and compliance. You will play a key role in shaping the future of cancer treatment, contributing to life-saving therapies. This is a significant opportunity to join a world-class organisation and make a profound impact on patient lives globally. The role demands a deep understanding of both pre-clinical and clinical development phases, with a focus on translating scientific discoveries into effective treatments. Expertise in specific oncology sub-specialties, such as immunotherapy or targeted therapy, is highly desirable. You will be at the cutting edge of pharmaceutical research, contributing to a culture of innovation and scientific excellence.
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Senior Clinical Research Scientist - Oncology Drug Development
M1 1AA Manchester, North West
£70000 Annually
WhatJobs
Posted 6 days ago
Job Viewed
Job Description
Our client, a leading biopharmaceutical innovator, is seeking a highly motivated Senior Clinical Research Scientist to join their cutting-edge oncology research team. This fully remote position offers the unique opportunity to contribute significantly to the development of novel cancer therapies from anywhere in the UK. You will be at the forefront of scientific advancement, playing a pivotal role in the design, execution, and interpretation of clinical trials that have the potential to transform patient lives.
Key Responsibilities:
Qualifications and Experience:
This is a crucial role for an accomplished scientist passionate about making a difference in the fight against cancer. Join our innovative client and shape the future of oncology treatments.
Key Responsibilities:
- Design and develop clinical trial protocols for oncology assets, ensuring scientific rigor and regulatory compliance.
- Oversee the execution of clinical studies, providing scientific and medical expertise to cross-functional teams.
- Analyze and interpret complex clinical trial data, including efficacy and safety endpoints.
- Collaborate with regulatory affairs, statistics, and medical writing teams to prepare submissions and publications.
- Stay abreast of the latest scientific advancements, emerging trends, and competitive landscape in oncology drug development.
- Identify and engage with key opinion leaders (KOLs) and investigators in the field.
- Contribute to the strategic planning and decision-making processes for the oncology portfolio.
- Develop and present scientific data internally and externally at conferences and meetings.
- Ensure adherence to Good Clinical Practice (GCP) guidelines and all relevant regulations.
- Mentor junior scientists and contribute to the growth of the research department.
Qualifications and Experience:
- Ph.D. or M.D. in a relevant life science discipline (e.g., Oncology, Immunology, Pharmacology).
- Minimum of 5-7 years of experience in clinical research and drug development, with a significant focus on oncology.
- Demonstrated experience in designing and managing complex clinical trials (Phase I-III).
- In-depth knowledge of oncology disease areas, drug mechanisms, and current treatment paradigms.
- Strong understanding of regulatory requirements (FDA, EMA) and GCP.
- Excellent analytical, statistical interpretation, and problem-solving skills.
- Exceptional written and verbal communication skills, with a proven track record of scientific publications and presentations.
- Ability to work effectively in a remote, fast-paced, and collaborative environment.
- Experience with data management systems and statistical analysis software is a plus.
- Strong leadership potential and ability to influence cross-functional teams.
This is a crucial role for an accomplished scientist passionate about making a difference in the fight against cancer. Join our innovative client and shape the future of oncology treatments.
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7
Principal Clinical Research Scientist - Oncology Drug Development
G1 1AA Glasgow, Scotland
£90000 Annually
WhatJobs
Posted 13 days ago
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Job Description
Our client, a leading pharmaceutical innovator, is seeking a highly accomplished Principal Clinical Research Scientist to spearhead critical oncology drug development programs. This role requires a deep scientific understanding of cancer biology, extensive experience in clinical trial design and execution, and a passion for bringing life-changing therapies to patients. You will collaborate with world-class researchers and clinicians to advance novel treatments from early-stage research through to regulatory submission.
Responsibilities:
Responsibilities:
- Lead the scientific strategy and design of Phase I-III clinical trials for novel oncology therapeutics.
- Oversee the development of clinical protocols, investigator brochures, and other essential study documents.
- Provide scientific and clinical expertise to cross-functional teams, including clinical operations, data management, regulatory affairs, and biomarker development.
- Analyze and interpret complex clinical trial data, translating findings into strategic recommendations for drug development.
- Prepare high-quality scientific publications, abstracts, and presentations for key medical conferences and journals.
- Engage with key opinion leaders (KOLs) in oncology to gather insights and foster collaboration.
- Contribute to regulatory submissions (e.g., IND, NDA) by preparing relevant clinical sections.
- Stay abreast of the latest advancements in oncology research, emerging therapeutic modalities, and competitive landscape.
- Mentor and guide junior scientists and clinical development professionals.
- Ensure all clinical research activities comply with GCP, regulatory guidelines, and company policies.
- Ph.D. or M.D. in a relevant life sciences discipline (e.g., Oncology, Immunology, Molecular Biology).
- Minimum of 10 years of experience in clinical drug development, with a strong focus on oncology.
- Demonstrated success in designing and leading complex clinical trials.
- Expertise in cancer biology, tumor microenvironment, and current therapeutic strategies.
- In-depth knowledge of GCP, regulatory requirements, and clinical trial methodologies.
- Proven ability to analyze and interpret clinical data effectively.
- Excellent scientific writing and communication skills, with a track record of publications and presentations.
- Strong leadership capabilities and experience working in a matrixed environment.
- Ability to travel to Glasgow, Scotland, UK as required for key meetings and site visits.
- Experience with immuno-oncology and targeted therapies is highly desirable.
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8
Principal Scientist - Drug Discovery & Preclinical Development
PO1 3AX Portsmouth, South East
£85000 Annually
WhatJobs
Posted 24 days ago
Job Viewed
Job Description
Our client, a dynamic and innovative pharmaceutical company, is seeking a highly accomplished Principal Scientist to join their cutting-edge Drug Discovery team. This senior role is pivotal in identifying, validating, and advancing novel therapeutic targets through preclinical development. You will lead multifaceted research projects, employing state-of-the-art techniques in molecular biology, pharmacology, and medicinal chemistry. The ideal candidate will possess a deep scientific understanding, exceptional leadership qualities, and a proven track record of successfully transitioning drug candidates from discovery into preclinical stages.
Responsibilities:
Qualifications:
Responsibilities:
- Lead the design and execution of drug discovery programs targeting key therapeutic areas.
- Identify and validate novel drug targets using a range of biochemical and cellular assays.
- Oversee preclinical studies, including in vitro and in vivo pharmacology, toxicology, and pharmacokinetics.
- Contribute to the development of innovative medicinal chemistry strategies.
- Analyze and interpret complex experimental data, drawing robust conclusions.
- Author and review research reports, scientific publications, and regulatory documents.
- Mentor and guide junior scientists and research associates.
- Collaborate effectively with internal departments and external partners.
- Present research findings at scientific conferences and to senior management.
- Stay abreast of the latest scientific advancements and technological innovations in pharmaceutical research.
Qualifications:
- PhD in Pharmacology, Biochemistry, Molecular Biology, or a closely related discipline.
- Extensive (10+ years) post-doctoral experience in pharmaceutical drug discovery and preclinical development.
- Demonstrated success in leading drug discovery projects and achieving key milestones.
- Expertise in relevant therapeutic areas and disease mechanisms.
- Proficiency in a broad range of biochemical, cellular, and molecular biology techniques.
- Experience with small molecule and/or biologics drug development.
- Strong understanding of regulatory requirements for preclinical development.
- Excellent leadership, communication, and interpersonal skills.
- Proven ability to manage multiple projects simultaneously and drive results.
This advertiser has chosen not to accept applicants from your region.
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