2,176 Drug Development jobs in the United Kingdom
Principal Formulation Scientist - Drug Development
NG1 6AE Nottingham, East Midlands
£80000 Annually
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Our client, a leading pharmaceutical company dedicated to advancing healthcare through innovative drug development, is seeking an experienced and highly skilled Principal Formulation Scientist to join their dynamic R&D team in Nottingham, Nottinghamshire, UK . This critical role will involve leading the development of novel drug delivery systems and innovative formulations for a diverse pipeline of pharmaceutical products. You will be at the forefront of designing, optimizing, and scaling up formulations, ensuring product efficacy, stability, and bioavailability. The ideal candidate will possess a deep understanding of pharmaceutical sciences, particularly in pre-formulation, formulation development, and manufacturing processes. Responsibilities include conducting pre-formulation studies, designing and executing experiments for solid dosage forms, sterile injectables, or other relevant delivery routes, and characterizing formulation performance. You will lead the troubleshooting of formulation challenges and provide expert scientific guidance to project teams. The Principal Formulation Scientist will play a key role in the transition of formulations from laboratory scale to clinical manufacturing and beyond. Collaboration with cross-functional teams, including analytical development, DMPK, regulatory affairs, and manufacturing, is essential. You will also contribute to the scientific strategy of the formulation department, stay abreast of emerging technologies, and potentially mentor junior scientists. A strong publication record and experience with intellectual property development are desirable. This hybrid role offers a blend of essential lab-based work and remote strategic planning and analysis, providing a balanced and productive work environment. This is an excellent opportunity to contribute to life-changing medicines within a supportive and scientifically driven organization in Nottingham .
Qualifications:
Qualifications:
- Ph.D. in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related field
- Minimum of 7 years of progressive experience in pharmaceutical formulation development
- Proven expertise in developing various dosage forms (e.g., oral solids, injectables, topical)
- Strong understanding of pre-formulation, excipient selection, and drug-excipient compatibility
- Hands-on experience with formulation characterization techniques (e.g., DSC, TGA, XRPD, dissolution)
- Experience with pilot-scale formulation manufacturing and technology transfer
- Knowledge of GMP guidelines and regulatory requirements for drug development
- Excellent problem-solving, analytical, and critical thinking skills
- Strong project management and organizational abilities
- Effective communication and interpersonal skills for cross-functional collaboration
- Ability to mentor junior scientists and contribute to scientific strategy
- Experience with specific therapeutic areas is a plus
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Pharmaceutical Formulation Scientist - Drug Development
MK9 2EZ Milton Keynes, South East
£60000 Annually
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Our client, a leading pharmaceutical company dedicated to advancing healthcare solutions, is seeking a skilled and innovative Pharmaceutical Formulation Scientist to join their research and development team in Milton Keynes, Buckinghamshire, UK . This role is pivotal in the early-stage development of novel drug formulations, contributing to the creation of effective and patient-centric medicines. The ideal candidate will possess a strong background in pharmaceutical sciences, with hands-on experience in formulation development and characterization. Responsibilities will include:
- Designing, developing, and optimizing oral solid dosage forms (tablets, capsules) and potentially other dosage forms.
- Conducting pre-formulation studies to understand the physicochemical properties of active pharmaceutical ingredients (APIs) and excipients.
- Evaluating and selecting appropriate excipients to achieve desired drug release profiles and stability.
- Utilizing various laboratory techniques for formulation preparation and characterization (e.g., particle size analysis, dissolution testing, differential scanning calorimetry).
- Developing and validating analytical methods for drug product testing.
- Conducting stability studies to assess the shelf-life and performance of formulations under various conditions.
- Troubleshooting formulation challenges and proposing innovative solutions.
- Collaborating with analytical development, process development, and regulatory affairs teams.
- Documenting experimental procedures, results, and reports in accordance with company standards and regulatory guidelines.
- Staying current with scientific literature and industry trends in pharmaceutical formulation and drug delivery.
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Senior Formulation Scientist - Drug Development
BS1 6GU Bristol, South West
£55000 Annually
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Our client is seeking a highly motivated and experienced Senior Formulation Scientist to join their dynamic drug development team in Bristol, South West England, UK . This role is pivotal in the progression of novel therapeutic candidates from early-stage research through to clinical trials and eventual market launch. You will be responsible for the design, development, and optimization of various pharmaceutical dosage forms, including oral solids, injectables, and topicals.
Key responsibilities include:
The ideal candidate will possess a Ph.D. or a Master's degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related discipline, with a minimum of 5 years of hands-on experience in pharmaceutical formulation development. A strong understanding of physical pharmacy principles, drug delivery technologies, and regulatory requirements is essential. Excellent problem-solving skills, strong written and verbal communication abilities, and the capacity to work independently and as part of a team are crucial. Experience with lyophilization or complex parenteral formulations would be a significant advantage. This hybrid role offers a fantastic opportunity to make a tangible impact on patient lives while advancing your career in a leading pharmaceutical research environment.
Key responsibilities include:
- Leading the formulation development of new chemical entities (NCEs) and existing drug products.
- Designing and executing experiments to investigate drug solubility, stability, bioavailability, and release profiles.
- Utilizing a range of analytical techniques (e.g., HPLC, GC, dissolution testing, DSC, TGA) to characterize formulations and raw materials.
- Troubleshooting formulation challenges and proposing innovative solutions.
- Preparing detailed scientific reports, development protocols, and contributing to regulatory submission documents.
- Collaborating effectively with cross-functional teams, including analytical development, process chemistry, manufacturing, and regulatory affairs.
- Mentoring junior scientists and contributing to the technical development of the team.
- Staying abreast of the latest scientific literature, industry trends, and regulatory guidelines related to pharmaceutical formulation.
- Ensuring all work is conducted in compliance with Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) standards.
The ideal candidate will possess a Ph.D. or a Master's degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related discipline, with a minimum of 5 years of hands-on experience in pharmaceutical formulation development. A strong understanding of physical pharmacy principles, drug delivery technologies, and regulatory requirements is essential. Excellent problem-solving skills, strong written and verbal communication abilities, and the capacity to work independently and as part of a team are crucial. Experience with lyophilization or complex parenteral formulations would be a significant advantage. This hybrid role offers a fantastic opportunity to make a tangible impact on patient lives while advancing your career in a leading pharmaceutical research environment.
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Senior Formulation Scientist (Drug Development)
LE1 7RW Leicester, East Midlands
£55000 Annually
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Our client, a leading pharmaceutical company, is seeking an accomplished Senior Formulation Scientist to join their cutting-edge research and development department based in Leicester, Leicestershire . This is a crucial laboratory-based role focused on developing innovative drug formulations that enhance therapeutic efficacy and patient compliance. You will be instrumental in the entire lifecycle of formulation development, from early-stage concept to late-stage clinical support.
Responsibilities:
Responsibilities:
- Design and execute experiments to develop novel drug formulations (e.g., oral solid dosage forms, injectables, topical preparations) for small molecules and biologics.
- Investigate and optimize pre-formulation properties, including solubility, stability, and compatibility studies.
- Develop and validate analytical methods for characterizing drug substances and drug products.
- Conduct stability studies according to ICH guidelines and interpret results to establish shelf-life.
- Prepare formulation development reports, present findings at internal meetings, and contribute to regulatory submissions.
- Collaborate with cross-functional teams, including analytical development, process development, regulatory affairs, and manufacturing.
- Troubleshoot formulation-related issues encountered during development and scale-up.
- Stay abreast of scientific literature, emerging technologies, and industry best practices in pharmaceutical formulation.
- Supervise and mentor junior scientists and technicians within the formulation team.
- Ensure all laboratory activities are conducted in compliance with GMP and safety regulations.
- Participate in technology transfer activities to manufacturing sites.
- Ph.D. or Master's degree in Pharmaceutics, Chemistry, Pharmaceutical Sciences, or a related discipline.
- Minimum of 5-7 years of progressive experience in pharmaceutical formulation development.
- Hands-on experience with a variety of dosage forms and formulation techniques.
- Strong understanding of physical chemistry, materials science, and drug delivery principles.
- Proficiency in analytical techniques such as HPLC, DSC, TGA, XRPD, and microscopy.
- Experience with formulation development software and statistical analysis tools.
- Excellent problem-solving, analytical, and critical thinking skills.
- Strong written and verbal communication skills, with the ability to effectively present technical information.
- Ability to work effectively in a fast-paced, collaborative laboratory environment.
- Knowledge of regulatory requirements (e.g., FDA, EMA) related to drug development and manufacturing.
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Principal Formulation Scientist (Drug Development)
CB2 1DR Cambridge, Eastern
£90000 Annually
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Our client, a pioneering biopharmaceutical company based in the vibrant scientific hub of **Cambridge**, is seeking an exceptional Principal Formulation Scientist to lead innovative drug development initiatives. This is a fully remote, high-impact role offering the chance to work at the forefront of pharmaceutical research and development from your preferred location. You will be responsible for the design, development, and optimization of novel drug delivery systems and formulations, driving projects from early-stage concept through to preclinical and clinical evaluation. This position requires deep scientific expertise, a rigorous experimental approach, and a strategic vision for advancing therapeutic solutions.
Responsibilities:
Qualifications:
This is a unique opportunity to join a dynamic research organization and contribute significantly to the development of life-changing medicines. If you are a visionary scientist passionate about pushing the boundaries of pharmaceutical formulation, we invite you to apply for this exciting remote role.
Responsibilities:
- Lead the formulation development of complex pharmaceutical products, including small molecules, biologics, and advanced therapies.
- Design and execute experimental strategies to optimize drug solubility, stability, bioavailability, and release profiles.
- Utilize a range of characterization techniques (e.g., HPLC, DLS, DSC, SEM) to assess formulation performance.
- Develop and validate analytical methods for formulation analysis.
- Manage and mentor a team of formulation scientists and technicians.
- Collaborate closely with cross-functional teams including medicinal chemistry, process development, DMPK, and clinical operations.
- Interpret experimental data, troubleshoot formulation challenges, and propose innovative solutions.
- Prepare comprehensive technical reports, protocols, and regulatory submission documents.
- Stay abreast of scientific literature, emerging technologies, and industry trends in formulation science.
- Contribute to the strategic direction of the R&D pipeline and intellectual property development.
Qualifications:
- Ph.D. in Pharmaceutical Sciences, Chemical Engineering, Materials Science, or a related discipline.
- Minimum of 8 years of progressive experience in pharmaceutical formulation development within the biotech or pharmaceutical industry.
- Demonstrated expertise in a variety of dosage forms (e.g., oral, injectable, topical) and delivery technologies.
- In-depth understanding of drug substance properties and their impact on formulation.
- Proficiency with common laboratory equipment and analytical instrumentation used in formulation science.
- Strong project management skills and experience leading R&D projects.
- Excellent written and verbal communication skills, with a proven ability to present complex scientific information.
- Experience with preclinical and/or early-phase clinical studies is highly advantageous.
- Ability to work independently and as part of a distributed, global team.
- A strong publication record or patent contributions is a plus.
This is a unique opportunity to join a dynamic research organization and contribute significantly to the development of life-changing medicines. If you are a visionary scientist passionate about pushing the boundaries of pharmaceutical formulation, we invite you to apply for this exciting remote role.
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Senior Formulation Scientist - Drug Development
L3 4AD Liverpool, North West
£70000 Annually
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Our client is seeking an accomplished Senior Formulation Scientist to join their innovative pharmaceutical research and development team based in **Liverpool, Merseyside, UK**. This critical role involves leading the design, development, and optimization of novel drug formulations, from early-stage research through to clinical trial supply. You will be instrumental in translating scientific concepts into viable drug products, addressing complex formulation challenges, and ensuring regulatory compliance. The ideal candidate possesses extensive experience in pharmaceutical formulation, a strong understanding of drug delivery systems, and a proven ability to lead projects and mentor junior scientists.
Key Responsibilities:
Qualifications:
This hybrid role offers a balanced approach to work, combining essential in-lab activities with the flexibility to work remotely. You will be part of a dynamic and collaborative environment at the forefront of pharmaceutical innovation, contributing directly to the development of life-changing medicines. Our client offers a competitive compensation package, excellent benefits, and significant opportunities for professional growth and career advancement within the pharmaceutical industry.
Key Responsibilities:
- Lead the formulation development of new drug candidates, including small molecules and biologics.
- Design and execute experiments to characterize drug substances and excipients.
- Develop and optimize dosage forms (e.g., oral solids, injectables, topical).
- Investigate and resolve formulation-related issues encountered during development.
- Develop and validate analytical methods for formulation characterization.
- Conduct stability studies and interpret results to define shelf-life.
- Prepare comprehensive formulation development reports and regulatory submission documents.
- Collaborate closely with analytical development, DMPK, and manufacturing teams.
- Stay current with scientific literature, industry trends, and regulatory guidelines.
- Mentor and guide junior formulation scientists, fostering a culture of scientific excellence.
Qualifications:
- A Ph.D. or Master's degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related field.
- A minimum of 5-7 years of experience in pharmaceutical formulation development.
- In-depth knowledge of various dosage forms, drug delivery technologies, and excipient functionalities.
- Experience with pre-formulation studies, solubility enhancement techniques, and analytical characterization.
- Proficiency in experimental design and statistical analysis.
- Strong understanding of regulatory requirements (e.g., ICH guidelines).
- Excellent problem-solving, organizational, and project management skills.
- Effective written and verbal communication abilities, with experience presenting to cross-functional teams and stakeholders.
- Demonstrated leadership potential and experience mentoring team members.
This hybrid role offers a balanced approach to work, combining essential in-lab activities with the flexibility to work remotely. You will be part of a dynamic and collaborative environment at the forefront of pharmaceutical innovation, contributing directly to the development of life-changing medicines. Our client offers a competitive compensation package, excellent benefits, and significant opportunities for professional growth and career advancement within the pharmaceutical industry.
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5
Lead Formulation Scientist, Drug Development
L1 8JQ Liverpool, North West
£75000 Annually
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Our client is seeking an experienced and visionary Lead Formulation Scientist to drive innovation within their Pharmaceutical division in **Liverpool, Merseyside, UK**. This hybrid role combines essential on-site laboratory work with flexible remote responsibilities. You will be instrumental in the design, development, and optimization of novel drug delivery systems and formulations, from early-stage research through to clinical development and commercialization. This position requires a deep understanding of pharmaceutical sciences, material science, and drug product manufacturing processes. You will lead a team of scientists, manage projects, and collaborate with cross-functional teams to advance pipeline assets.
Key Responsibilities:
Key Responsibilities:
- Lead the formulation development of new chemical entities and complex drug products (e.g., injectables, oral solids, biologics).
- Design and execute experimental studies to evaluate drug solubility, stability, bioavailability, and manufacturability.
- Develop and optimize formulation strategies to achieve desired therapeutic profiles and patient compliance.
- Characterize drug product performance using a range of analytical techniques.
- Oversee technology transfer activities to manufacturing sites and support process validation.
- Manage project timelines, resources, and budgets, ensuring timely delivery of milestones.
- Mentor and guide junior formulation scientists, fostering a culture of scientific excellence and innovation.
- Collaborate closely with preclinical, clinical, regulatory, and manufacturing teams.
- Author and review technical reports, protocols, and regulatory submission documents.
- Stay current with industry trends, new technologies, and regulatory guidelines in pharmaceutical formulation.
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Principal Formulation Scientist - Drug Development
SR1 2AY Sunderland, North East
£70000 Annually
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Our client, a cutting-edge pharmaceutical research and development company, is seeking a highly experienced Principal Formulation Scientist to join their fully remote R&D team. This senior role is instrumental in driving the innovation and development of novel drug delivery systems and pharmaceutical formulations. You will lead the scientific direction for formulation development projects, from early-stage concept through to pre-clinical and clinical readiness, contributing significantly to the company's pipeline.
Key Responsibilities:
The ideal candidate will possess a Ph.D. or Master's degree in Pharmaceutics, Pharmaceutical Sciences, Chemistry, or a related discipline, with a minimum of 8 years of progressive experience in pharmaceutical formulation development. A deep understanding of formulation science principles, excipient functionality, and various drug delivery technologies is crucial. Proven experience in leading complex R&D projects and mentoring scientific staff is required. Excellent communication, problem-solving, and organizational skills are essential for success in this remote-first environment. Proficiency in relevant laboratory techniques and analytical methods is expected. This position, though located conceptually near Sunderland, Tyne and Wear, UK , operates entirely remotely.
Key Responsibilities:
- Lead the design, development, and optimization of complex pharmaceutical formulations (e.g., oral solid dosage, parenteral, topical) for new chemical entities and existing drug products.
- Develop and execute comprehensive experimental plans to assess formulation performance, stability, and manufacturability.
- Provide strategic scientific leadership and technical guidance to a team of formulation scientists and technicians.
- Troubleshoot formulation challenges and identify innovative solutions to overcome development hurdles.
- Conduct in-depth literature reviews and stay current with emerging technologies and scientific advancements in pharmaceutics and drug delivery.
- Prepare and review detailed technical reports, study protocols, and regulatory submission documents (e.g., IND, NDA).
- Collaborate effectively with cross-functional teams, including analytical development, process chemistry, DMPK, and clinical operations, in a remote setting.
- Present scientific findings and project updates to internal stakeholders and external partners.
- Contribute to the intellectual property strategy through patent filings and publications.
- Ensure all activities are conducted in compliance with GMP, GLP, and other relevant regulatory guidelines.
The ideal candidate will possess a Ph.D. or Master's degree in Pharmaceutics, Pharmaceutical Sciences, Chemistry, or a related discipline, with a minimum of 8 years of progressive experience in pharmaceutical formulation development. A deep understanding of formulation science principles, excipient functionality, and various drug delivery technologies is crucial. Proven experience in leading complex R&D projects and mentoring scientific staff is required. Excellent communication, problem-solving, and organizational skills are essential for success in this remote-first environment. Proficiency in relevant laboratory techniques and analytical methods is expected. This position, though located conceptually near Sunderland, Tyne and Wear, UK , operates entirely remotely.
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Principal Scientist - Drug Discovery & Development
BD3 0HF Bradford, Yorkshire and the Humber
£75000 Annually
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Our client is a leading pharmaceutical innovator seeking a highly accomplished Principal Scientist to drive critical drug discovery and development initiatives within their state-of-the-art research facility located in **Bradford, West Yorkshire, UK**. This pivotal role involves leading complex research projects, from target identification and validation through to preclinical development, contributing significantly to the company's pipeline of novel therapeutics. You will leverage your deep scientific expertise and extensive experience to guide research strategies, foster innovation, and ensure the efficient progression of drug candidates.
Key Responsibilities:
Key Responsibilities:
- Lead and manage multiple drug discovery projects from concept to preclinical candidate selection.
- Design and execute complex biological experiments to investigate disease mechanisms and identify novel therapeutic targets.
- Develop and optimize assay development strategies for high-throughput screening and compound characterization.
- Analyze and interpret experimental data, making critical decisions on project direction and go/no-go criteria.
- Collaborate closely with internal teams (e.g., medicinal chemistry, pharmacology, DMPK) and external partners to advance drug candidates.
- Stay current with scientific literature and emerging technologies in relevant therapeutic areas and drug discovery methodologies.
- Prepare and present research findings to senior management, scientific committees, and at external conferences.
- Contribute to the development of intellectual property and regulatory submissions.
- Mentor and guide junior scientists, fostering a culture of scientific excellence and collaboration.
- Ensure compliance with all relevant safety, ethical, and regulatory guidelines.
- Ph.D. in Molecular Biology, Biochemistry, Pharmacology, or a closely related life science discipline.
- A minimum of 8-10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
- Demonstrated success in leading drug discovery projects and bringing candidates into preclinical development.
- Extensive knowledge of various drug discovery platforms and modalities (e.g., small molecules, biologics).
- Proficiency in experimental design, data analysis, and interpretation using relevant software.
- Excellent understanding of relevant therapeutic areas (e.g., oncology, immunology, neuroscience).
- Strong leadership, project management, and communication skills.
- Proven ability to work effectively in a multidisciplinary, matrixed environment.
- Experience with manuscript preparation and scientific presentation is essential.
- A strong publication record in peer-reviewed journals is highly desirable.
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Principal Scientist - Drug Discovery & Development
M1 1JN Manchester, North West
£80000 Annually
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Our client, a leading global pharmaceutical company at the forefront of developing life-changing therapies, is seeking an exceptional Principal Scientist to drive innovation within their Drug Discovery & Development division. Based at their state-of-the-art research facility in Manchester, Greater Manchester, UK , this senior role requires a visionary leader with extensive expertise in identifying, validating, and advancing novel drug targets. You will be responsible for conceptualizing and executing complex research programs, leading a team of talented scientists, and collaborating across multidisciplinary teams to accelerate the pipeline from early discovery through to pre-clinical development. The ideal candidate will possess a deep scientific understanding, a proven track record in medicinal chemistry or pharmacology, and a passion for pushing the boundaries of pharmaceutical research.
Key Responsibilities:
This is a unique opportunity to shape the future of medicine within a world-class research environment in Manchester.
Key Responsibilities:
- Lead and manage cutting-edge research projects focused on the discovery and development of novel therapeutics for unmet medical needs.
- Design and implement innovative experimental strategies to identify and validate drug targets.
- Oversee the synthesis, characterization, and optimization of potential drug candidates, utilizing expertise in medicinal chemistry or pharmacology.
- Provide scientific leadership and mentorship to a team of research scientists and technicians.
- Develop and maintain strong collaborations with internal R&D teams, external academic institutions, and CROs.
- Interpret complex scientific data, draw conclusions, and make strategic recommendations for project progression.
- Prepare high-quality research reports, publications, and patent applications.
- Ensure all research activities adhere to stringent quality, safety, and regulatory standards.
- Contribute to the strategic direction of the drug discovery portfolio.
- Present research findings at internal reviews and external scientific conferences.
- Manage budgets and resources allocated to research projects.
- Stay abreast of the latest scientific advancements and emerging technologies in relevant therapeutic areas.
- PhD in Pharmacology, Medicinal Chemistry, Biochemistry, Molecular Biology, or a closely related field.
- Minimum of 10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
- Demonstrated success in leading drug discovery programs from target identification to pre-clinical candidate selection.
- Extensive knowledge of drug discovery processes, including target validation, lead identification, and lead optimization.
- Proven expertise in a specific therapeutic area (e.g., oncology, immunology, CNS).
- Strong understanding of modern drug discovery technologies and methodologies.
- Excellent leadership, team management, and mentoring skills.
- Exceptional analytical, problem-solving, and critical thinking abilities.
- Strong publication record and experience with patent filings.
- Excellent written and verbal communication skills, with the ability to effectively present complex scientific information.
- Experience working within a GLP environment is advantageous.
This is a unique opportunity to shape the future of medicine within a world-class research environment in Manchester.
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