287 Drug Development jobs in the United Kingdom
Drug Product Process Development Scientist
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Job Title – Drug Product Process Development Scientist
Location – Slough
Contract Length / Perm – 12 months
Pay Rate – £24 p/h PAYE
We are seeking a skilled Drug Product Development Specialist to support the development of injectable drug products from early clinical phases through to regulatory approval. This is a 12-month contract role within the Pharmaceutical Development Sciences (PDS) team, focused on ensuring robust, compliant, and scalable manufacturing processes for sterile injectable medicines.
Key Responsibilities
- Lead the design and optimization of injectable drug product manufacturing processes (liquid and lyophilized forms).
- Define process parameters for clinical manufacturing and support preparation for regulatory submissions.
- Collaborate with internal teams and external partners, including contract manufacturing organizations.
- Conduct lab-based studies to support drug product development (e.g., filter sizing, compatibility assessments, fill volume testing).
- Analyze critical process data to improve understanding and ensure process robustness.
- Perform risk assessments and support process validation activities.
- Ensure compliance with cGMP, quality standards, and regulatory requirements.
- Contribute to clinical trial preparation and support the manufacture of stability and clinical batches.
- Assist in responding to regulatory queries and resolving quality-related issues.
- Support knowledge transfer from development to commercial manufacturing.
Requirements
- 2–3 years of experience in drug product development or manufacturing within the pharmaceutical industry.
- Experience in biopharmaceuticals and aseptic manufacturing (e.g., vial, syringe, cartridge filling) is a plus.
- Strong understanding of sterile drug product components, process scale-up, and optimization.
- Familiarity with regulatory standards and cGMP practices.
Drug Product Process Development Scientist
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Scientist - Injectable Drug Product Process Development
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Help bring science to life and join a leading pharmaceutical company to play a key role in delivering impactful medicines that drives healthcare innovation!
Hobson Prior is seeking a Drug Product Development Specialist to join a dynamic team within Pharmaceutical Development Sciences. This role focuses on injectable drug product manufacturing processes, supporting clinical and regulatory activities. You will collaborate with internal teams and external partners to ensure the successful development and production of sterile drug products.
Please note that to be considered for this role you must have the right to work in this location.
Responsibilities:
- Develop and refine manufacturing processes for injectable drug products from early studies to regulatory approval.
- Select and define manufacturing parameters for clinical production.
- Collaborate with internal teams and external manufacturers to meet project goals.
- Conduct lab studies, analyse data, and document findings (e.g., filter selection, fill volume assessments, compatibility tests).
- Analyse manufacturing data to improve process understanding and performance.
- Perform risk assessments for manufacturing processes.
- Design processes for sterile injectable products in various forms (e.g., liquid, lyophilized powder, pre-filled syringes).
- Support clinical trial preparation and ensure timely production of stability and clinical batches.
- Assist in process validation and ensure compliance with quality standards and regulations.
- Contribute to regulatory submissions and respond to authority queries.
- Investigate and resolve quality-related issues, such as deviations or complaints.
- Facilitate knowledge transfer from late-phase development to commercial production.
- Help improve departmental processes and ways of working.
Key Skills and Requirements:
- Experience in developing or manufacturing liquid drug products in the pharmaceutical industry.
- Familiarity with biopharmaceuticals is a plus.
- Knowledge of aseptic manufacturing processes, including vial, cartridge, and pre-filled syringe filling, is advantageous.
- Understanding of sterile drug product development, including components, process transfer, scale-up, and optimization, is beneficial.
For more information, please contact Jessica Taylor.
If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists visit the 'Contact Us' page.
Hobson Prior is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Hobson Prior is acting as an Employment Agency in relation to this vacancy.
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Scientist - Injectable Drug Product Process Development
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Pharmaceutical Research Scientist - Drug Discovery
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As a Pharmaceutical Research Scientist, your core focus will be on identifying and validating novel therapeutic targets, designing and synthesizing potential drug candidates, and conducting preclinical studies. You will be involved in all stages of the drug discovery pipeline, from initial hypothesis generation to lead optimization. This requires a deep understanding of medicinal chemistry, pharmacology, molecular biology, and assay development. You will be expected to design and execute complex experiments, analyze data rigorously, and interpret results in the context of therapeutic potential.
Key responsibilities include developing and implementing in vitro and in vivo assays to evaluate drug efficacy and safety, performing structure-activity relationship (SAR) studies, and contributing to the formulation of candidate drugs. You will collaborate closely with a multidisciplinary team of chemists, biologists, toxicologists, and clinicians to advance projects towards clinical trials. Maintaining meticulous laboratory records, contributing to patent applications, and presenting research findings at internal and external scientific meetings will be essential aspects of the role. Staying abreast of the latest scientific literature and technological advancements in drug discovery is crucial.
The ideal candidate will hold a Ph.D. or Master's degree in Pharmacology, Medicinal Chemistry, Biology, or a related life science discipline, with a proven track record of successful research in drug discovery, evidenced by publications and/or patent filings. Experience with small molecule drug discovery and proficiency in relevant laboratory techniques and analytical methods are essential. Strong knowledge of disease biology and target validation pathways is highly desirable. Excellent analytical, problem-solving, and critical thinking skills are paramount. This hybrid role requires strong collaboration skills and the ability to work effectively both independently in the lab and remotely on data analysis and scientific writing. If you are passionate about making a difference in patient lives through innovative pharmaceutical research, we encourage you to apply.
Pharmaceutical Research Scientist - Drug Discovery
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The successful candidate will play a crucial role in identifying and validating novel drug targets, designing and executing experiments, and analyzing complex biological data to advance early-stage drug discovery programs. Responsibilities include developing and optimizing in vitro and ex vivo assays, performing compound screening, and contributing to the interpretation of results. You will work collaboratively within multidisciplinary teams, including chemists, biologists, and pharmacologists, to progress promising therapeutic candidates.
Key requirements include a PhD or Master's degree in a relevant life science discipline (e.g., pharmacology, molecular biology, biochemistry) with a strong track record of research experience in drug discovery. Proficiency in standard molecular and cellular biology techniques, data analysis software (e.g., GraphPad Prism), and experience with relevant therapeutic areas are essential. The ability to meticulously document experimental procedures and results, prepare scientific reports, and present findings to internal stakeholders is paramount. While the role requires significant time in the lab, certain data analysis, literature reviews, and report writing components can be performed remotely. We are looking for an inquisitive and detail-oriented individual with excellent problem-solving skills and a passion for developing life-changing medicines.
Principal Scientist, Drug Discovery
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Key Responsibilities:
- Lead and manage research projects focused on identifying and characterizing novel drug targets for unmet medical needs.
- Design, implement, and optimize complex experimental assays and protocols using state-of-the-art technologies.
- Interpret experimental data, draw robust conclusions, and present findings clearly and concisely to scientific teams and senior management.
- Develop and implement innovative scientific strategies to accelerate the drug discovery pipeline.
- Collaborate effectively with internal multidisciplinary teams (e.g., chemistry, biology, DMPK, toxicology) and external partners.
- Mentor and guide junior scientists, fostering a culture of scientific rigor, innovation, and collaboration.
- Contribute to the preparation of scientific publications, patent applications, and regulatory submissions.
- Stay abreast of the latest scientific literature, industry trends, and technological advancements in relevant therapeutic areas.
- Manage laboratory resources and budgets effectively.
- PhD in Molecular Biology, Pharmacology, Biochemistry, or a related life science discipline.
- Minimum of 8 years of post-doctoral and/or industry experience in drug discovery research.
- Proven track record of scientific leadership and success in identifying and validating drug targets.
- Extensive hands-on experience with a range of biological assays and techniques relevant to drug discovery.
- Strong understanding of disease biology and mechanisms of action.
- Excellent analytical, problem-solving, and critical thinking skills.
- Exceptional written and verbal communication skills, with a strong publication record.
- Demonstrated ability to work independently and collaboratively in a fast-paced, team-oriented environment.
- Experience in bioinformatics and computational biology is a plus.
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Principal Scientist - Drug Discovery
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Responsibilities:
- Lead and manage multiple drug discovery projects, from target identification through lead optimization and preclinical candidate selection.
- Design and execute complex experiments to validate novel therapeutic targets and identify small molecule or biologic drug candidates.
- Develop and implement innovative research strategies to address unmet medical needs.
- Interpret experimental data, troubleshoot complex problems, and make critical decisions regarding project direction.
- Collaborate closely with internal cross-functional teams (e.g., chemistry, biology, DMPK, toxicology) and external partners.
- Mentor and guide junior scientists, fostering their professional development and scientific growth.
- Stay abreast of the latest scientific advancements, technologies, and trends in relevant therapeutic areas and drug discovery methodologies.
- Contribute to the preparation of scientific publications, patents, and regulatory submissions.
- Present research findings at internal meetings and external scientific conferences.
- Manage research budgets and resource allocation effectively.
- Ensure compliance with all relevant ethical, safety, and regulatory guidelines.
- Contribute to the strategic planning and scientific direction of the drug discovery portfolio.
- Evaluate new technologies and methodologies to enhance the drug discovery platform.
- Maintain meticulous records of experimental procedures and results.
- Ph.D. in Molecular Biology, Biochemistry, Pharmacology, Medicinal Chemistry, or a related life science discipline.
- Minimum of 8 years of post-doctoral and industry experience in drug discovery, with a significant portion in a leadership or Principal Scientist role.
- Demonstrated expertise in at least one key area of drug discovery (e.g., small molecule discovery, biologics development, target validation).
- Proven track record of successfully advancing drug candidates through the discovery pipeline.
- Strong understanding of assay development, screening technologies, and data analysis.
- Exceptional leadership, communication, presentation, and interpersonal skills.
- Experience in managing project teams and external collaborations.
- Ability to think critically and strategically, with strong problem-solving capabilities.
- Proficiency in relevant scientific literature databases and research tools.
- Publications in high-impact peer-reviewed journals and a strong scientific network are highly desirable.
Principal Scientist - Drug Discovery
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- Design, plan, and execute complex research projects in drug discovery, with a focus on specific therapeutic areas.
- Lead a team of scientists and researchers, providing technical guidance, mentorship, and project oversight.
- Develop and implement novel experimental methodologies and assays to support target identification and validation.
- Analyze and interpret complex experimental data, draw conclusions, and communicate findings effectively through reports and presentations.
- Contribute to the development of strategic research plans and contribute to intellectual property generation.
- Collaborate closely with medicinal chemists, biologists, pharmacologists, and other scientific disciplines.
- Stay abreast of the latest scientific literature, technological advancements, and industry trends in drug discovery.
- Ensure adherence to all safety protocols and laboratory best practices.
- Present research findings at internal meetings and external scientific conferences.
- Ph.D. in Molecular Biology, Biochemistry, Pharmacology, or a related life science discipline.
- Minimum of 8 years of post-doctoral research experience in the pharmaceutical or biotechnology industry, with a strong focus on drug discovery.
- Demonstrated expertise in designing and conducting in vitro and/or in vivo studies.
- Proven track record of successful project leadership and managing research teams.
- Extensive knowledge of relevant therapeutic areas and target classes.
- Strong publication record in high-impact peer-reviewed journals.
- Excellent analytical, problem-solving, and critical thinking skills.
- Superb communication, presentation, and interpersonal skills.
- Experience with computational biology or bioinformatics tools is a plus.
Principal Scientist - Drug Discovery
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Key Responsibilities:
- Lead and manage drug discovery research programs within specified therapeutic areas.
- Design, develop, and implement cutting-edge research strategies and experimental protocols.
- Conduct complex biological experiments and interpret data to drive project progression.
- Identify and validate novel drug targets and therapeutic mechanisms.
- Develop and optimize biochemical and cellular assays.
- Collaborate effectively with interdisciplinary teams, including medicinal chemists, biologists, and clinical researchers.
- Mentor and guide junior scientists and research associates.
- Author and present scientific findings at internal meetings and external conferences.
- Contribute to the preparation of regulatory submissions and scientific publications.
- Stay current with the latest scientific literature and technological advancements in drug discovery.
- Contribute to intellectual property generation and protection.
- Ensure adherence to all safety and laboratory management protocols.
Qualifications and Experience:
- PhD in Molecular Biology, Pharmacology, Biochemistry, or a related life science discipline.
- Minimum of 8-10 years of post-doctoral and industry experience in drug discovery.
- Demonstrated success in leading research projects from conception to delivery.
- Expertise in one or more relevant therapeutic areas (e.g., oncology, immunology, neuroscience).
- Strong proficiency in a broad range of biological techniques and assay development.
- Proven experience in data analysis and interpretation using statistical software.
- Excellent communication, presentation, and interpersonal skills.
- Strong leadership and team management capabilities.
- Experience with biostatistics and computational biology is advantageous.
- Publications in peer-reviewed journals and a strong scientific network.