7,358 Drug Development jobs in the United Kingdom
Principal Scientist - Drug Discovery & Development
Posted 9 days ago
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Job Description
Key Responsibilities:
- Design, execute, and interpret complex experiments to drive drug discovery programmes forward.
- Lead and mentor a team of talented research scientists and technicians, fostering a culture of scientific excellence and collaboration.
- Develop and validate novel assays and technologies to support drug discovery efforts.
- Identify and evaluate promising therapeutic targets and lead compounds.
- Oversee preclinical studies, including in vitro and in vivo models, to assess compound efficacy and safety.
- Collaborate effectively with cross-functional teams, including chemistry, pharmacology, toxicology, and translational science.
- Author high-quality scientific reports, manuscripts, and patent applications.
- Present research findings at internal meetings and external scientific conferences.
- Manage external collaborations with academic institutions and contract research organizations (CROs).
- Contribute to strategic planning for the R&D pipeline and portfolio management.
- Ensure compliance with all relevant laboratory safety regulations and best practices.
- Stay abreast of the latest scientific advancements and competitive landscape in relevant therapeutic areas.
- Ph.D. in Pharmacology, Molecular Biology, Biochemistry, Immunology, or a related life science discipline.
- Minimum of 10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry, with a strong focus on drug discovery.
- Demonstrated leadership experience in managing scientific teams and projects.
- Deep expertise in (Specific therapeutic area relevant to fictional company, e.g., oncology, infectious diseases, neuroscience) and associated drug discovery methodologies.
- Proficiency in a wide range of in vitro and in vivo experimental techniques.
- Proven ability to design and execute complex research strategies and troubleshoot effectively.
- Excellent analytical, problem-solving, and critical thinking skills.
- Exceptional written and verbal communication skills, with a track record of publications and presentations.
- Experience with biostatistics and data analysis software.
- Strong project management skills and the ability to manage multiple priorities.
- A passion for scientific innovation and a commitment to developing novel therapeutics.
Principal Scientist - Drug Discovery & Development
Posted 14 days ago
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Job Description
Principal Scientist - Drug Discovery & Development
Posted 14 days ago
Job Viewed
Job Description
Key Responsibilities:
- Lead and execute complex research projects focused on novel therapeutic targets and drug candidates.
- Design and implement in vitro and in vivo experimental studies to assess drug efficacy, safety, and pharmacokinetics.
- Analyze and interpret complex biological data, drawing insightful conclusions and proposing next steps.
- Develop and validate new assays and methodologies to support drug discovery programs.
- Collaborate effectively with internal teams (chemistry, biology, DMPK) and external partners to advance pipeline projects.
- Provide scientific leadership and mentorship to junior scientists and research associates.
- Stay at the forefront of scientific literature, identifying emerging trends and opportunities in pharmaceutical research.
- Prepare high-quality scientific reports, presentations, and manuscripts for internal and external dissemination.
- Contribute to the strategic direction of the company's research pipeline and portfolio.
- PhD in Molecular Biology, Pharmacology, Biochemistry, or a related life science discipline.
- 10+ years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
- Proven track record of successfully leading drug discovery projects from target identification through preclinical development.
- Extensive experience with various biological assays, molecular biology techniques, and cell-based models.
- Strong understanding of immunology, oncology, or other relevant therapeutic areas.
- Demonstrated ability to design, execute, and interpret complex experiments.
- Exceptional critical thinking, problem-solving, and analytical skills.
- Excellent written and verbal communication skills, with a talent for presenting complex scientific information.
- Experience mentoring and managing scientific staff is essential.
Principal Scientist - Drug Discovery & Development
Posted 24 days ago
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Job Description
Key Responsibilities:
- Lead and manage multiple drug discovery projects from concept to preclinical candidate selection.
- Design and execute complex biological experiments to investigate disease mechanisms and identify novel therapeutic targets.
- Develop and optimize assay development strategies for high-throughput screening and compound characterization.
- Analyze and interpret experimental data, making critical decisions on project direction and go/no-go criteria.
- Collaborate closely with internal teams (e.g., medicinal chemistry, pharmacology, DMPK) and external partners to advance drug candidates.
- Stay current with scientific literature and emerging technologies in relevant therapeutic areas and drug discovery methodologies.
- Prepare and present research findings to senior management, scientific committees, and at external conferences.
- Contribute to the development of intellectual property and regulatory submissions.
- Mentor and guide junior scientists, fostering a culture of scientific excellence and collaboration.
- Ensure compliance with all relevant safety, ethical, and regulatory guidelines.
- Ph.D. in Molecular Biology, Biochemistry, Pharmacology, or a closely related life science discipline.
- A minimum of 8-10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
- Demonstrated success in leading drug discovery projects and bringing candidates into preclinical development.
- Extensive knowledge of various drug discovery platforms and modalities (e.g., small molecules, biologics).
- Proficiency in experimental design, data analysis, and interpretation using relevant software.
- Excellent understanding of relevant therapeutic areas (e.g., oncology, immunology, neuroscience).
- Strong leadership, project management, and communication skills.
- Proven ability to work effectively in a multidisciplinary, matrixed environment.
- Experience with manuscript preparation and scientific presentation is essential.
- A strong publication record in peer-reviewed journals is highly desirable.
Principal Pharmaceutical Scientist - Drug Discovery & Development
Posted 22 days ago
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Job Description
As a remote-first employee, you will leverage state-of-the-art digital collaboration tools to work seamlessly with interdisciplinary teams, including chemists, biologists, pharmacologists, and regulatory affairs specialists. This role demands a strategic thinker with a proven ability to drive projects forward, overcome complex scientific challenges, and contribute to the submission of robust regulatory dossiers.This is a 100% remote role, based anywhere in the UK.
Key Responsibilities:
- Lead the design and execution of drug discovery and early development programs, focusing on (specific therapeutic areas, e.g., oncology, immunology, neurology).
- Develop and implement innovative strategies for hit-to-lead and lead optimization, utilizing a deep understanding of medicinal chemistry, pharmacology, and drug metabolism.
- Oversee in vitro and in vivo studies to assess the efficacy, safety, and pharmacokinetic properties of drug candidates.
- Critically evaluate experimental data, interpret results, and make data-driven decisions to guide project progression.
- Prepare high-quality scientific reports, presentations, and publications for internal review and external dissemination.
- Contribute significantly to the preparation of regulatory documents, such as Investigational New Drug (IND) applications and New Drug Applications (NDA).
- Mentor and guide junior scientists, fostering a culture of scientific excellence and collaboration.
- Manage external research collaborations and contract research organizations (CROs) effectively.
- Represent the company at scientific conferences and engage with the broader research community.
Qualifications:
- Ph.D. in Pharmacology, Medicinal Chemistry, Biochemistry, or a related life sciences discipline.
- Minimum of 8 years of progressive experience in drug discovery and development within the pharmaceutical or biotechnology industry.
- Extensive experience in (specific therapeutic area) is highly preferred.
- Demonstrated success in advancing drug candidates from discovery through preclinical development.
- Strong knowledge of drug discovery processes, including target identification, lead optimization, and ADME/Tox studies.
- Proficiency in experimental design, data analysis, and interpretation.
- Excellent written and verbal communication skills, with a track record of contributing to regulatory submissions.
- Proven leadership abilities and experience mentoring scientific staff.
- Ability to work independently and collaboratively in a remote, fast-paced research environment.
- A strong publication record in peer-reviewed journals is a significant asset.
Senior Pharmaceutical Scientist - Drug Discovery & Development
Posted 24 days ago
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Job Description
Key Responsibilities:
- Design, conduct, and optimize in vitro and in vivo studies to evaluate the efficacy and safety of drug candidates.
- Develop and validate biological assays to support drug discovery and development programs.
- Analyze and interpret complex experimental data, employing statistical methods and scientific rigor.
- Contribute to the preparation of research reports, regulatory submissions, and scientific publications.
- Collaborate effectively with cross-functional teams, including medicinal chemists, pharmacologists, toxicologists, and formulation scientists.
- Stay abreast of the latest scientific advancements, literature, and technologies in pharmaceutical sciences.
- Manage research projects, including resource allocation, timeline management, and budget adherence.
- Mentor and guide junior scientists, fostering a culture of scientific excellence and continuous learning.
- Contribute to the identification and validation of novel drug targets.
- Ensure adherence to all laboratory safety protocols and Good Laboratory Practice (GLP) guidelines.
Qualifications:
- PhD in Pharmacology, Medicinal Chemistry, Biochemistry, or a related life science discipline.
- Minimum of 5 years of post-doctoral or industry experience in drug discovery and development.
- Proven track record of scientific contributions, demonstrated through publications and presentations.
- Extensive experience with a range of drug discovery techniques and methodologies.
- Strong understanding of preclinical development pathways and regulatory requirements.
- Excellent analytical, problem-solving, and critical thinking skills.
- Proficiency in data analysis software and scientific literature databases.
- Strong written and verbal communication skills.
- Ability to work independently and collaboratively within a team in **Liverpool, Merseyside, UK**.
Lead Clinical Research Scientist - Oncology Drug Development
Posted 2 days ago
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Senior Clinical Research Scientist - Oncology Drug Development
Posted 6 days ago
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Key Responsibilities:
- Design and develop clinical trial protocols for oncology assets, ensuring scientific rigor and regulatory compliance.
- Oversee the execution of clinical studies, providing scientific and medical expertise to cross-functional teams.
- Analyze and interpret complex clinical trial data, including efficacy and safety endpoints.
- Collaborate with regulatory affairs, statistics, and medical writing teams to prepare submissions and publications.
- Stay abreast of the latest scientific advancements, emerging trends, and competitive landscape in oncology drug development.
- Identify and engage with key opinion leaders (KOLs) and investigators in the field.
- Contribute to the strategic planning and decision-making processes for the oncology portfolio.
- Develop and present scientific data internally and externally at conferences and meetings.
- Ensure adherence to Good Clinical Practice (GCP) guidelines and all relevant regulations.
- Mentor junior scientists and contribute to the growth of the research department.
Qualifications and Experience:
- Ph.D. or M.D. in a relevant life science discipline (e.g., Oncology, Immunology, Pharmacology).
- Minimum of 5-7 years of experience in clinical research and drug development, with a significant focus on oncology.
- Demonstrated experience in designing and managing complex clinical trials (Phase I-III).
- In-depth knowledge of oncology disease areas, drug mechanisms, and current treatment paradigms.
- Strong understanding of regulatory requirements (FDA, EMA) and GCP.
- Excellent analytical, statistical interpretation, and problem-solving skills.
- Exceptional written and verbal communication skills, with a proven track record of scientific publications and presentations.
- Ability to work effectively in a remote, fast-paced, and collaborative environment.
- Experience with data management systems and statistical analysis software is a plus.
- Strong leadership potential and ability to influence cross-functional teams.
This is a crucial role for an accomplished scientist passionate about making a difference in the fight against cancer. Join our innovative client and shape the future of oncology treatments.
Principal Clinical Research Scientist - Oncology Drug Development
Posted 13 days ago
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Job Description
Responsibilities:
- Lead the scientific strategy and design of Phase I-III clinical trials for novel oncology therapeutics.
- Oversee the development of clinical protocols, investigator brochures, and other essential study documents.
- Provide scientific and clinical expertise to cross-functional teams, including clinical operations, data management, regulatory affairs, and biomarker development.
- Analyze and interpret complex clinical trial data, translating findings into strategic recommendations for drug development.
- Prepare high-quality scientific publications, abstracts, and presentations for key medical conferences and journals.
- Engage with key opinion leaders (KOLs) in oncology to gather insights and foster collaboration.
- Contribute to regulatory submissions (e.g., IND, NDA) by preparing relevant clinical sections.
- Stay abreast of the latest advancements in oncology research, emerging therapeutic modalities, and competitive landscape.
- Mentor and guide junior scientists and clinical development professionals.
- Ensure all clinical research activities comply with GCP, regulatory guidelines, and company policies.
- Ph.D. or M.D. in a relevant life sciences discipline (e.g., Oncology, Immunology, Molecular Biology).
- Minimum of 10 years of experience in clinical drug development, with a strong focus on oncology.
- Demonstrated success in designing and leading complex clinical trials.
- Expertise in cancer biology, tumor microenvironment, and current therapeutic strategies.
- In-depth knowledge of GCP, regulatory requirements, and clinical trial methodologies.
- Proven ability to analyze and interpret clinical data effectively.
- Excellent scientific writing and communication skills, with a track record of publications and presentations.
- Strong leadership capabilities and experience working in a matrixed environment.
- Ability to travel to Glasgow, Scotland, UK as required for key meetings and site visits.
- Experience with immuno-oncology and targeted therapies is highly desirable.
Principal Scientist - Drug Discovery & Preclinical Development
Posted 24 days ago
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Job Description
Responsibilities:
- Lead the design and execution of drug discovery programs targeting key therapeutic areas.
- Identify and validate novel drug targets using a range of biochemical and cellular assays.
- Oversee preclinical studies, including in vitro and in vivo pharmacology, toxicology, and pharmacokinetics.
- Contribute to the development of innovative medicinal chemistry strategies.
- Analyze and interpret complex experimental data, drawing robust conclusions.
- Author and review research reports, scientific publications, and regulatory documents.
- Mentor and guide junior scientists and research associates.
- Collaborate effectively with internal departments and external partners.
- Present research findings at scientific conferences and to senior management.
- Stay abreast of the latest scientific advancements and technological innovations in pharmaceutical research.
Qualifications:
- PhD in Pharmacology, Biochemistry, Molecular Biology, or a closely related discipline.
- Extensive (10+ years) post-doctoral experience in pharmaceutical drug discovery and preclinical development.
- Demonstrated success in leading drug discovery projects and achieving key milestones.
- Expertise in relevant therapeutic areas and disease mechanisms.
- Proficiency in a broad range of biochemical, cellular, and molecular biology techniques.
- Experience with small molecule and/or biologics drug development.
- Strong understanding of regulatory requirements for preclinical development.
- Excellent leadership, communication, and interpersonal skills.
- Proven ability to manage multiple projects simultaneously and drive results.