7,280 Research And Development Departments jobs in the United Kingdom

Job Title : Research Scientist - Protein

Working Location : Bracknell

Rate : £18.41 per hour

Contract Length : 12 months

Start Date : 19th January 2026

We are looking for a hardworking, motivated individual who is quick to learn and apply themselves to join our dynamic, collaborative and industrious protein production team. This is a one-year contract to support the delivery of a critical protein production process. This role offers the opportunity for the successful candidate to gain hands on experience with an array of downstream processing techniques including protein chromatography and membrane filtration methods.

Role profile and expectations:

• Work as part of a protein production team to deliver gram quantities of purified recombinant protein to support one of Syngenta’s critical commercial projects
• Provide hands-on support during this large-scale protein production campaign
• Learn and conduct the necessary analytical methods to validate final outputs meet defined specifications
• Accurately record results to agreed company standards
• Prepare technical reports, present findings within project groups and be an active communicator within the wider Syngenta scientific community
• Work safely and with due care to others ensuring compliance with company HSE policies

Essential education & experience:

• Bachelor’s degree in relevant science e.g. Biology, Biochemistry, Biomedical or other similar disciplines
• Good theoretical understanding of recombinant protein expression
• Good theoretical understanding of chromatography techniques including affinity, ion exchange (IEX), hydrophobic interaction (HIC) and size exclusion (SEC) chromatography
• Strong evidence of troubleshooting and innovative problem solving
• Ability to work independently and as part of a team
• Good communication and planning skills

Desirable experience:

• Master’s degree or 1-2 years’ experience working in a laboratory environment
• 1-2 years lab experience working in any of the core areas highlighted in the above job description
• Experience with data management tools (e.g. Benchling) and data analysis software (e.g. JMP)
• Experience of working with scalable bioprocess technologies e.g. TFF, Hollow fibre

Research Scientist

Oxford

About Exogene

At Exogene, we’re reimagining what’s possible in cancer immunotherapy. Our mission is to engineer T-cell receptor therapies that can precisely and powerfully target advanced solid tumours.

To do this, we’ve built a proprietary lab-in-the-loop platform that merges generative AI, biophysical modelling, and high-throughput TCR screening to rapidly design, test, and optimise TCRs with exceptional affinity and specificity. This convergence of computation and wet-lab experimentation allows us to go from concept to candidate molecules in record time.

We’re developing TCR-based trispecific T cell engagers (TCR-TriTCEs)—a new therapeutic modality designed to overcome the unique challenges of the solid tumour microenvironment. This work spans multiple disciplines, from protein engineering and AI-driven design to in vivo validation and translational development.

We are looking for a dynamic research scientist who will help drive the TCR engineering processes and development. The successful candidate will contribute to in vivo and in vitro validation of TCEs. You’ll get involved in purifying recombinant TCRs to perform high-throughput TCR display methods and deep sequencing.

Responsibilities

• Contribute to in vivo and in vitro validation of TCEs.
• Collaboratively design and characterise TCRs for proprietary and partnered disease targets.
• Conduct a suite of protein science operations, including expression, purification, and biophysical analysis.
• Tackle molecular biology duties: cloning, mutagenesis, DNA isolation, and preparing libraries for deep sequencing.
• Manage tissue culture assignments, spanning from media prep and cell line care to cryopreservation.
• Join forces with founders, R&D, academia, and industrial stakeholders to fulfil ambitious R&D objectives.
• Draft, revise, and oversee repertoire of lab protocols.
• Offer essential lab support and uphold facility upkeep.

Skills and Qualifications

• PhD in Immunology, Cell Biology, Biochemistry, or an alike field, paired with at least 1-2 years of relevant lab experience is required.
• Knowledge of molecular biology protocols, with an emphasis on cloning and PCR is preferred.
• A background in molecular biology, protein expression, purification and biophysical characterisation is preferred.
• Experience in cell and immunological assays (flow cytometry, ELISA etc.) is desired.
• Experience with in vivo and in vitro validation of TCEs (T-cell engagers) in some or all aspects of investigational new drug (IND) approval is desired.
• Experience TCR engineering is desired.
• SOP documentation experience is desired.
• The highest standards in lab precision, record maintenance, and documentation.
• Excellent written and oral communication skills.

Attributes

• Self-starter with sound analytical skills, who values scientific integrity and novelty.
• Collaborative spirit within the lab, open to both giving and receiving actionable feedback.
• Exceptional at diagnosing and overcoming unforeseen technical challenges.
• Adept at juggling and prioritising multiple projects to meet deadlines.
• Versatile and efficient within an interdisciplinary, fast-paced team setup.

What We Offer

• Market-competitive salary and stock option package.
• A generous leave policy: 25 days holiday, public holidays, plus a day off for your birthday!
• Access to fully equipped private lab.
• Flexibility to work from home as project demands allow.
• A supportive, cross-disciplinary team fostering a highly collaborative work environment.

How to apply

Launch your journey with Exogene by submitting your CV and a brief cover letter (maximum 400 words) to m.hasan at exogene.co.uk

Research Scientist | Series A BioTech Startup | £16M+ Raised

Salary: £0,000 – £8 000

Location: London / Hybrid

About the Opportunity

We’re proud to be partnered with a Series A BioTech startup that has raised over £1 million to accelerate the development of next-generation therapeutics through cutting-edge biological and technological innovation.

Backed by leading investors and built by a world-class founding team, this company is entering an exciting phase of growth, expanding its R&D capabilities and scaling breakthrough science into real-world impact.

As a Research Scientist , you’ll join a small, mission-driven team working at the intersection of biology, technology, and data. You’ll take a hands-on role in the lab, designing and executing experiments that drive discovery and shape the company’s R&D pipeline.

Key Responsibilities

• Design, execute, and analyse experiments supporting the company’s core discovery programs.
• Develop, optimise, and validate assays, workflows, and protocols to advance R&D.
• Maintain accurate and organised documentation (ELNs, reports, and presentations).
• Present experimental findings to the leadership and cross-functional teams.
• Collaborate with computational scientists, engineers, and biologists to translate data into insight.
• Stay current on emerging methods and technologies that can accelerate innovation.
• Contribute to building scientific culture, infrastructure, and lab best practices in a growing startup.

About You

Education & Experience

• PhD (or MSc with strong hands-on experience) in Molecular Biology, Biotechnology, Biochemistry, or Life Sciences .
• Postdoctoral or early-stage industry experience preferred — but scientific curiosity, creativity, and rigour matter most.

Technical Skills

• Proficiency in molecular and/or cellular biology techniques.
• Previous experience in a biotech or startup research environment advantageous.

Soft Skills

• Self-starter who thrives in a fast-paced, collaborative setting.
• Excellent communicator and problem-solver with a rigorous scientific mindset.
• Adaptable team player who enjoys contributing across multiple disciplines.
• Driven by innovation and the opportunity to create meaningful impact through science.

Why Join?

Mission-Driven Impact – Contribute to the discovery of breakthrough therapies in a high-growth BioTech.

Research Scientist

Excellerate Bioscience Ltd are currently seeking a highly motivated candidate with an in vitro pharmacology background to join our team. We offer a dynamic team environment, working in partnership with our clients to provide flexible solutions from early-stage target identification to late stage detailed mechanism of action studies, across a range of different drug target classes and disease areas.

Role and Responsibilities

As a Scientist and member of a pharmacology group, you will work as part of a team to develop cell-based, biochemical or pharmacology assays to enable quantitative and rigorous characterization of complex protein-ligand interactions at the molecular level to aid target identification, validation and lead optimisation strategies in support of drug discovery programs across a variety of target classes.

Skills and Experience:

• A BSc / MSc focused on biochemistry, cell biology, pharmacology or related discipline (Essential). Previous industrial or research/academic laboratory experience would be advantageous.
• Familiarity with one or more of the following areas: a) Compound Profiling/in vitro assay development, b) Receptor Pharmacology c) Protein-protein interactions d) Cellular Pharmacology.
• Familiarity with methodologies such as cell culture, cell signalling assays, reporter assays, western blotting, molecular biology.
• Knowledge of working with semi-automated liquid handling systems, preferably working in a 96/384 well format.
• A strong ability to problem-solve and take the lead on project work when needed.
• Excellent interpersonal, collaborative and communication skills.

What we Offer:

Our benefits package includes a competitive salary, pension contribution, plus additional benefits. This position is based at our new state-of-the-art central Nottingham facility.

Only applicants that have eligibility to work in the UK will be considered for the role. Please send your CV with a covering letter outlining why you feel you would be suitable for this role.

Job Type: Full-time

Pay: From £25,000.00 per year

Benefits:

• On-site parking

Ability to commute/relocate:

• Nottingham, NG2 1AE: reliably commute or plan to relocate before starting work (required)

Education:

• Bachelor's (required)

Work authorisation:

• United Kingdom (required)

Work Location: In person

Reference ID: EXCResearchScientist 25

Research Scientist

Oxford

About Exogene

At Exogene, we’re reimagining what’s possible in cancer immunotherapy. Our mission is to engineer T-cell receptor therapies that can precisely and powerfully target advanced solid tumours.

To do this, we’ve built a proprietary lab-in-the-loop platform that merges generative AI, biophysical modelling, and high-throughput TCR screening to rapidly design, test, and optimise TCRs with exceptional affinity and specificity. This convergence of computation and wet-lab experimentation allows us to go from concept to candidate molecules in record time.

We’re developing TCR-based trispecific T cell engagers (TCR-TriTCEs)—a new therapeutic modality designed to overcome the unique challenges of the solid tumour microenvironment. This work spans multiple disciplines, from protein engineering and AI-driven design to in vivo validation and translational development.

We are looking for a dynamic research scientist who will help drive the TCR engineering processes and development. The successful candidate will contribute to in vivo and in vitro validation of TCEs. You’ll get involved in purifying recombinant TCRs to perform high-throughput TCR display methods and deep sequencing.

Responsibilities

• Contribute to in vivo and in vitro validation of TCEs.
• Collaboratively design and characterise TCRs for proprietary and partnered disease targets.
• Conduct a suite of protein science operations, including expression, purification, and biophysical analysis.
• Tackle molecular biology duties: cloning, mutagenesis, DNA isolation, and preparing libraries for deep sequencing.
• Manage tissue culture assignments, spanning from media prep and cell line care to cryopreservation.
• Join forces with founders, R&D, academia, and industrial stakeholders to fulfil ambitious R&D objectives.
• Draft, revise, and oversee repertoire of lab protocols.
• Offer essential lab support and uphold facility upkeep.

Skills and Qualifications

• PhD in Immunology, Cell Biology, Biochemistry, or an alike field, paired with at least 1-2 years of relevant lab experience is required.
• Knowledge of molecular biology protocols, with an emphasis on cloning and PCR is preferred.
• A background in molecular biology, protein expression, purification and biophysical characterisation is preferred.
• Experience in cell and immunological assays (flow cytometry, ELISA etc.) is desired.
• Experience with in vivo and in vitro validation of TCEs (T-cell engagers) in some or all aspects of investigational new drug (IND) approval is desired.
• Experience TCR engineering is desired.
• SOP documentation experience is desired.
• The highest standards in lab precision, record maintenance, and documentation.
• Excellent written and oral communication skills.

Attributes

• Self-starter with sound analytical skills, who values scientific integrity and novelty.
• Collaborative spirit within the lab, open to both giving and receiving actionable feedback.
• Exceptional at diagnosing and overcoming unforeseen technical challenges.
• Adept at juggling and prioritising multiple projects to meet deadlines.
• Versatile and efficient within an interdisciplinary, fast-paced team setup.

What We Offer

• Market-competitive salary and stock option package.
• A generous leave policy: 25 days holiday, public holidays, plus a day off for your birthday!
• Access to fully equipped private lab.
• Flexibility to work from home as project demands allow.
• A supportive, cross-disciplinary team fostering a highly collaborative work environment.

How to apply

Launch your journey with Exogene by submitting your CV and a brief cover letter (maximum 400 words) to m.hasan at exogene.co.uk

Research Scientist in Biokinetics

Rate : £17.82 per hour

Location : Bracknell, Jealotts Hill

Contract Length : 24 months

About this opportunity:

Our client is looking for a Research Scientist who has proven experience in a research setting to join the Bioperformance group. The Bioperformance group within the Bioscience function in Crop Protection conducts research on the ADME (Absorption, Distribution, Metabolism and Elimination) behaviour of active ingredients (AIs) within target and non-target species to understand critical performance characteristics such as selectivity, resistance and translation to and in the field.

Role purpose and key requirements :

The successful candidate will work on a variety of projects, from early-stage research to product development and market support. They will use a combination of lab and glasshouse assays as well as analytical techniques, to produce high quality data on the bioavailability of active ingredients and products.

We are looking for someone with at least two years’ experience of working in a laboratory, a degree, MSc (preferred) or PhD, in a Biological Science subject and preferably some experience of working in plant science or insect science.

Additionally, the candidate must show good personal management skills, such as following science plans, delivering results in line with the project timelines, and complying with HSE standards. The candidate must have a team mentality, effective interpersonal and communications skills, and be able to work with colleagues from various disciplines.

The role will involve:

Core tasks

Proactively providing the scientific and technical support to inform about the bioavailability of novel agrochemicals by performing studies in whole plants / insects (in vivo) or plant parts and insect tissues (ex vivo).

Responsible for independently designing, planning, executing and analysing experiments to further our understanding of how AIs interact with in plant or insect matrixes.

Interpretating and analysing data and presenting conclusions in detailed reports and presentations.

Performing operational priorities that are agreed with the Science Leader.

Implementing HSE actions to ensure the operations are within defined standards.

Additional tasks

Reviewing and advancing established protocols or methodology that improves capability and efficiency.

Transferring knowledge and building new capabilities to supplement existing toolkits.

What are we looking for:

Essential:

• BSc or MSc (preferred) with experience in subject areas related to Plant Biology, Biochemistry, Chemistry and/or Soil Science.

• At least two years of relevant laboratory-based experience, either in a relevant professional or academic setting.

• Effective scientific writing (fluent in English), verbal communication, and organizational skills.

Desirable:

• Some professional experience working in Pharmacology, Agronomy, Crop Protection, Biochemistry or Analytical Chemistry.

• Experience in handling large data sets – data storage, reporting analysis, and visualization tools.

• Experience in the study of ADME of active ingredients.

• Experience of analysing small molecules using LC-MS.

• Experience working with soil, seeds, plants or insects.

What we offer:

Comprehensive training in all techniques including the use of LCMS based analysis and 14C imaging.

A great working environment at our International Research Centre with well-equipped laboratories, open culture and a diverse workforce.

The opportunity to work with and learn from highly qualified, experienced employees and gain scientific and technical excellence.

This role is based at Jealott’s Hill and is for two years.

• Design and execute bioinformatics analyses for large-scale genomics, transcriptomics, proteomics, and metabolomics datasets.
• Develop and implement novel computational tools and algorithms to support research objectives.
• Collaborate with experimental biologists, clinicians, and other researchers to interpret biological data and generate actionable insights.
• Contribute to the conceptualization and design of new research projects and grant proposals.
• Manage bioinformatics workflows and pipelines, ensuring data integrity and reproducibility.
• Stay abreast of the latest advancements in bioinformatics, computational biology, and relevant scientific fields.
• Present research findings at internal meetings and external scientific conferences.
• Mentor junior scientists and contribute to the growth of the research team's computational capabilities.
• Author scientific publications in peer-reviewed journals.
• Ensure compliance with data management best practices and ethical guidelines.

• PhD in Bioinformatics, Computational Biology, Computer Science, Statistics, or a related quantitative field.
• Minimum of 6 years of post-doctoral research experience in bioinformatics or computational biology.
• Proven track record of leading successful research projects and contributing to high-impact publications.
• Expertise in analysing diverse biological datasets using statistical and machine learning methods.
• Proficiency in programming languages commonly used in bioinformatics (e.g., Python, R, Perl) and experience with bioinformatics software packages and databases.
• Strong understanding of molecular biology principles and experimental techniques.
• Excellent problem-solving, analytical, and critical-thinking skills.
• Outstanding communication and presentation skills, with the ability to articulate complex scientific concepts effectively.
• Experience with high-performance computing environments is a plus.
• Ability to work independently, manage priorities, and collaborate effectively in a remote research setting.

• Lead the design and execution of ambitious research projects in biotechnology, with a focus on developing novel therapeutics for unmet medical needs.
• Direct and mentor a team of research scientists and technicians, fostering a collaborative and high-performance research environment.
• Develop and implement innovative experimental strategies using advanced molecular biology, genomics, and proteomics techniques.
• Critically analyse complex biological data, interpret results, and draw robust conclusions to guide research direction.
• Contribute to the preparation of grant proposals and secure external funding for research initiatives.
• Publish findings in high-impact peer-reviewed journals and present research at international conferences.
• Collaborate effectively with cross-functional teams, including chemistry, pharmacology, and clinical development departments.
• Ensure compliance with all relevant ethical guidelines, regulatory requirements, and safety protocols within the laboratory.
• Identify emerging scientific trends and technologies relevant to the company's strategic goals.
• Contribute to the intellectual property strategy through patent filings and disclosures.

• A Ph.D. in Molecular Biology, Biochemistry, Genetics, Biotechnology, or a closely related life science discipline.
• A minimum of 10 years of post-doctoral research experience in an academic or industrial R&D setting.
• A distinguished track record of publications in leading scientific journals and successful grant acquisition.
• Extensive hands-on experience with advanced techniques such as CRISPR-Cas9, next-generation sequencing (NGS), mammalian cell culture, protein expression and purification, and various assay development platforms.
• Proven experience in leading and managing research projects and scientific teams.
• Strong understanding of drug discovery and development processes.
• Exceptional analytical, critical thinking, and problem-solving skills.
• Excellent written and verbal communication skills, with the ability to present complex scientific information effectively.
• A strategic mindset with the ability to identify and pursue novel research opportunities.
• Experience in bioinformatics and computational biology is advantageous.

• Designing and implementing advanced genomic research projects, including Next-Generation Sequencing (NGS) experiments.
• Developing and optimizing protocols for DNA/RNA extraction, library preparation, and sequencing.
• Analyzing large-scale genomic datasets using bioinformatics tools and statistical methods.
• Interpreting genomic data to identify disease markers, understand biological pathways, and drive therapeutic insights.
• Managing and maintaining genomic research infrastructure, including sequencing platforms and bioinformatics pipelines.
• Collaborating with internal and external research groups to foster new scientific partnerships.
• Preparing high-impact research publications for peer-reviewed journals and presenting findings at scientific conferences.
• Mentoring and providing technical guidance to junior scientists and research assistants.
• Ensuring strict adherence to all laboratory safety protocols and ethical guidelines.
• Contributing to the development of grant proposals and securing research funding.