685 Research And Development jobs in Derbyshire
Senior Pharmaceutical Research & Development Scientist
S1 1AA Sheffield, Yorkshire and the Humber
£65000 Annually
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Posted 1 day ago
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Job Description
Our client is recruiting a highly skilled and innovative Senior Pharmaceutical Research & Development Scientist to join their esteemed R&D department in Sheffield, South Yorkshire, UK . This pivotal role involves leading the development of novel pharmaceutical products and therapeutic solutions, from early-stage research through to pre-clinical development. The successful candidate will contribute significantly to the company's pipeline by designing, executing, and analyzing complex experiments, and driving projects towards successful outcomes. You will work within a state-of-the-art laboratory environment, collaborating with a multidisciplinary team of scientists and researchers.
Key responsibilities include designing and conducting in vitro and in vivo studies, developing and validating analytical methods, and interpreting experimental data to guide research direction. You will be responsible for staying current with scientific literature, regulatory guidelines, and emerging technologies within the pharmaceutical industry. The role also involves preparing research reports, contributing to regulatory submissions, and potentially mentoring junior scientists. The ideal candidate will possess a Ph.D. in Pharmacology, Pharmaceutical Sciences, Biochemistry, Molecular Biology, or a related field, coupled with a minimum of 5-7 years of relevant industry experience. Proven expertise in drug discovery and development, including experience with specific therapeutic areas (e.g., oncology, immunology, CNS), is highly desirable. Strong analytical skills, excellent problem-solving abilities, and proficiency in laboratory techniques are essential. You must possess outstanding communication and interpersonal skills, with the ability to present complex scientific information effectively. Experience with Good Laboratory Practice (GLP) and regulatory requirements is advantageous. This hybrid position offers a dynamic work environment, blending focused lab work with opportunities for remote data analysis and collaboration.
Key responsibilities include designing and conducting in vitro and in vivo studies, developing and validating analytical methods, and interpreting experimental data to guide research direction. You will be responsible for staying current with scientific literature, regulatory guidelines, and emerging technologies within the pharmaceutical industry. The role also involves preparing research reports, contributing to regulatory submissions, and potentially mentoring junior scientists. The ideal candidate will possess a Ph.D. in Pharmacology, Pharmaceutical Sciences, Biochemistry, Molecular Biology, or a related field, coupled with a minimum of 5-7 years of relevant industry experience. Proven expertise in drug discovery and development, including experience with specific therapeutic areas (e.g., oncology, immunology, CNS), is highly desirable. Strong analytical skills, excellent problem-solving abilities, and proficiency in laboratory techniques are essential. You must possess outstanding communication and interpersonal skills, with the ability to present complex scientific information effectively. Experience with Good Laboratory Practice (GLP) and regulatory requirements is advantageous. This hybrid position offers a dynamic work environment, blending focused lab work with opportunities for remote data analysis and collaboration.
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0
Clinical Research Associate - Pharmaceutical Development
S1 2EX Sheffield, Yorkshire and the Humber
£55000 Annually
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Posted 3 days ago
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Job Description
Our client, a leading pharmaceutical company, is seeking a meticulous and dedicated Clinical Research Associate (CRA) to join their drug development team. This role offers a hybrid working model, combining essential site visits with remote work, allowing for a balanced approach to clinical trial management. You will be responsible for the monitoring and management of clinical trials at investigator sites, ensuring compliance with Good Clinical Practice (GCP) guidelines, regulatory requirements, and study protocols. Your duties will include site selection and initiation, ongoing monitoring visits (source data verification, essential document review), and close-out activities. You will build and maintain strong relationships with investigators and site staff, providing training and support to ensure protocol adherence and data integrity. The ideal candidate will possess excellent communication, organizational, and problem-solving skills, with a keen eye for detail. A strong understanding of clinical trial processes, regulatory affairs, and medical terminology is essential. You will be adept at identifying and resolving site issues, escalating deviations as necessary, and contributing to the overall success of clinical trials. This role requires individuals who are proactive, can work independently, and are committed to ensuring the safety of trial participants and the quality of data collected. The ability to travel to sites across the region is a key requirement for this position.
Responsibilities:
Responsibilities:
- Conduct site initiation, monitoring, and close-out visits for clinical trials.
- Ensure compliance with GCP, ICH guidelines, and study protocols.
- Perform source data verification and review essential study documents.
- Train and support investigators and site staff on study requirements.
- Monitor patient safety and identify and report adverse events.
- Resolve site-level issues and escalate deviations as needed.
- Manage study timelines and budgets at the site level.
- Communicate effectively with internal teams, investigators, and regulatory authorities.
- Maintain accurate and up-to-date trial documentation.
- Contribute to the development of study protocols and other study documents.
- Bachelor's degree in Life Sciences, Nursing, Pharmacy, or a related field.
- Minimum of 3 years of experience as a Clinical Research Associate (CRA).
- Strong knowledge of GCP, ICH guidelines, and regulatory requirements.
- Experience in monitoring multi-center clinical trials.
- Excellent understanding of medical terminology and clinical trial processes.
- Proficiency in clinical trial management systems (CTMS) and electronic data capture (EDC) systems.
- Exceptional organizational and time management skills.
- Strong communication, interpersonal, and problem-solving abilities.
- Ability to travel to clinical sites as required.
- Detail-oriented with a commitment to data quality and patient safety.
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1
Research Scientist - Pharmaceutical Development
NG1 4BU Nottingham, East Midlands
£50000 Annually
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Posted 2 days ago
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Job Description
Our client, a cutting-edge scientific research and development organisation, is seeking a talented and dedicated Research Scientist to join their innovative pharmaceutical development team based in Nottingham, Nottinghamshire, UK . This role is central to advancing novel therapeutic candidates from early discovery through to preclinical development. You will conduct complex experiments, analyse data, and contribute significantly to the scientific strategy of the group. The ideal candidate will have a strong academic background in a relevant life science discipline, coupled with practical experience in drug discovery or development. You will be expected to work collaboratively within multidisciplinary teams, present findings at scientific meetings, and contribute to publications. Key responsibilities will include:
- Designing and executing in vitro and/or in vivo experiments to evaluate drug efficacy and safety.
- Developing and validating new assay methodologies.
- Analysing experimental data using appropriate statistical methods and software.
- Interpreting results and drawing conclusions to guide further research directions.
- Collaborating with chemists, biologists, and pharmacologists to integrate findings.
- Contributing to the preparation of technical reports, study protocols, and regulatory submissions.
- Keeping abreast of the latest scientific literature and technological advancements in relevant fields.
- Maintaining detailed laboratory notebooks and documenting all experimental procedures.
- Presenting research findings internally and potentially at external scientific conferences.
- Contributing to the intellectual property and patenting process.
- PhD in Pharmacology, Molecular Biology, Biochemistry, or a related life science field.
- Postdoctoral experience or 2+ years of industry experience in pharmaceutical R&D.
- Demonstrated expertise in relevant experimental techniques (e.g., cell culture, molecular biology assays, animal models, high-throughput screening).
- Strong understanding of drug discovery and development processes.
- Proficiency in data analysis and scientific software (e.g., GraphPad Prism, R).
- Excellent problem-solving and critical thinking skills.
- Strong written and oral communication skills, with a track record of scientific presentation.
- Ability to work effectively in a fast-paced, collaborative research environment.
- Meticulous attention to detail and commitment to scientific rigor.
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2
Research Scientist - Pharmaceutical Development
NG1 1GE Nottingham, East Midlands
£45000 Annually
WhatJobs
Posted 18 days ago
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Job Description
Our client, a prominent biopharmaceutical company, is seeking a highly skilled and motivated Research Scientist to join their drug discovery and development team in Nottingham, Nottinghamshire, UK . This hybrid role is central to advancing novel therapeutic candidates through the preclinical development pipeline. You will be responsible for designing and executing complex experiments, analysing data, and contributing to the strategic direction of research projects. Key responsibilities include developing and validating in vitro and in vivo assays to assess drug efficacy, toxicity, and pharmacokinetic profiles. You will play a crucial role in identifying and characterising new drug targets, and evaluating potential drug molecules using a range of biochemical, cellular, and molecular biology techniques. Extensive literature reviews, experimental design, and data interpretation will be integral to your daily work. Collaboration with cross-functional teams, including medicinal chemists, pharmacologists, and regulatory affairs specialists, is essential for project success. You will be expected to maintain meticulous laboratory records, prepare scientific reports, and present findings at internal meetings and scientific conferences. The ideal candidate will hold a PhD in Pharmacology, Biochemistry, Molecular Biology, or a related life science discipline, with a strong track record of research publications. Postdoctoral experience in a relevant area of drug discovery is highly desirable. Expertise in assay development, molecular cloning, cell culture techniques, and data analysis software is required. Experience with specific therapeutic areas or disease models relevant to the company's pipeline would be a significant advantage. You will possess excellent analytical and critical thinking skills, a strong understanding of the drug development process, and a passion for scientific innovation. The ability to work independently, manage multiple projects, and communicate complex scientific information effectively is essential. This is an outstanding opportunity to contribute to the development of life-changing medicines within a dynamic and collaborative research environment.
Key Responsibilities:
Qualifications:
Key Responsibilities:
- Design and conduct preclinical research experiments.
- Develop and validate biological assays.
- Investigate drug efficacy, safety, and mechanisms of action.
- Characterise novel drug targets and molecules.
- Perform molecular and cellular biology techniques.
- Analyse and interpret complex experimental data.
- Prepare scientific reports and presentations.
- Collaborate with multidisciplinary research teams.
- Maintain accurate laboratory records and documentation.
- Stay abreast of scientific literature and industry trends.
Qualifications:
- PhD in Pharmacology, Biochemistry, Molecular Biology, or related field.
- Proven research experience in drug discovery/development.
- Expertise in relevant experimental techniques (assay development, cell culture, molecular biology).
- Strong data analysis and interpretation skills.
- Excellent written and verbal communication skills.
- Ability to work independently and manage projects.
- Experience with relevant therapeutic areas is a plus.
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3
Clinical Research Associate
NG1 1AA Nottingham, East Midlands
£38000 Annually
WhatJobs
Posted 17 days ago
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Job Description
Our client, a leading pharmaceutical company, is seeking a dedicated Clinical Research Associate (CRA) to join their team in Nottingham, Nottinghamshire, UK . This hybrid role offers a blend of on-site and remote work, providing flexibility while ensuring critical project oversight. The CRA will play a vital role in ensuring the successful execution of clinical trials by monitoring study sites, verifying data accuracy, and ensuring compliance with protocols and regulatory guidelines (GCP, FDA, EMA). Responsibilities include site initiation visits, routine monitoring, close-out visits, and maintaining strong relationships with investigators and study staff. You will be responsible for ensuring that all trial-related documents are accurate, complete, and maintained meticulously. This role requires a proactive approach to problem-solving, identifying potential issues at study sites and implementing corrective actions swiftly. The ideal candidate will have a strong scientific background, typically a degree in a life science, nursing, or a related field, coupled with previous experience in clinical research or a similar role. Excellent understanding of ICH-Good Clinical Practice (GCP) guidelines and regulatory requirements is essential. Superior organizational skills, attention to detail, and effective communication abilities are paramount. You must be adept at working independently and as part of a larger team. Travel to study sites will be required as part of the role. This is an exceptional opportunity to contribute to groundbreaking pharmaceutical research and development in a supportive and forward-thinking organization.
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4
Senior Research Scientist, Pharmaceutical Development
NG1 3BP Nottingham, East Midlands
£70000 Annually
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Posted 2 days ago
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Job Description
Our client, a leading biopharmaceutical company, is seeking a highly skilled Senior Research Scientist to join their innovative Pharmaceutical Development team. This hybrid role, based in **Nottingham, Nottinghamshire, UK**, offers the chance to contribute to the advancement of novel therapeutics from early-stage research through to clinical development. You will be responsible for designing, executing, and analyzing complex research experiments related to drug discovery and formulation. This includes in-vitro and in-vivo studies, assay development, and data interpretation. The ideal candidate will possess a strong background in pharmacology, biochemistry, molecular biology, or a related life science discipline, with a proven track record of contributing to drug development programs. You will work collaboratively with cross-functional teams, including medicinal chemists, toxicologists, and clinical researchers, to achieve project milestones. Key responsibilities involve troubleshooting experimental challenges, developing and validating new scientific methodologies, and meticulously documenting research findings. Experience with specific therapeutic areas, such as oncology or infectious diseases, is highly desirable. You will also be expected to contribute to scientific publications, patent applications, and regulatory submissions. A proactive approach to problem-solving, strong analytical skills, and the ability to manage multiple projects simultaneously are essential. This is an excellent opportunity for a dedicated scientist to make a significant impact on patient lives through the development of groundbreaking medicines.
Key Responsibilities:
Key Responsibilities:
- Design and conduct in-vitro and in-vivo research studies.
- Develop and validate new assay methods for drug characterization.
- Analyze and interpret complex experimental data.
- Contribute to the formulation development of new drug candidates.
- Collaborate with cross-functional teams throughout the drug development lifecycle.
- Troubleshoot experimental issues and propose solutions.
- Prepare research reports, scientific publications, and presentations.
- Ensure compliance with GxP guidelines and laboratory safety standards.
- Stay updated on scientific literature and emerging technologies in pharmaceutical R&D.
- Mentor junior scientists and contribute to team development.
- Ph.D. in Pharmacology, Biochemistry, Molecular Biology, or a related life science field.
- Minimum of 5-7 years of relevant post-doctoral or industry research experience in drug discovery and development.
- Strong understanding of drug development processes and regulatory requirements.
- Proven experience in experimental design and data analysis.
- Proficiency with relevant laboratory techniques and instrumentation.
- Excellent written and oral communication skills.
- Ability to work independently and collaboratively in a team environment.
- Strong problem-solving and critical thinking abilities.
- Experience in a specific therapeutic area (e.g., oncology, immunology) is an asset.
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5
Senior Research Scientist - Pharmaceutical Development
S1 2AA Sheffield, Yorkshire and the Humber
£75000 Annually
WhatJobs
Posted 15 days ago
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Job Description
Our client is seeking an accomplished Senior Research Scientist to join their pioneering pharmaceutical development team. This is a critical role focused on driving innovative research initiatives from discovery through to early-stage development. You will be instrumental in designing and executing complex experiments, analyzing data, and contributing to the strategic direction of new drug candidates. The ideal candidate will possess a strong background in medicinal chemistry, pharmacology, or a related discipline, coupled with extensive experience in the pharmaceutical industry. You will work within state-of-the-art laboratory facilities, collaborating with a multidisciplinary team of scientists and clinicians to advance therapeutic breakthroughs. This role requires a highly motivated individual with exceptional scientific acumen and a commitment to pushing the boundaries of pharmaceutical science.
Key Responsibilities:
Qualifications:
This challenging and rewarding role is based in our client's cutting-edge facility in Sheffield, South Yorkshire, UK , offering the opportunity to make a significant impact on patient health through innovative pharmaceutical research.
Key Responsibilities:
- Lead and execute research projects focused on novel drug discovery and development.
- Design and conduct in vitro and in vivo experiments to evaluate drug efficacy and safety.
- Analyze experimental data, interpret results, and draw scientific conclusions.
- Develop and optimize new synthetic routes for small molecule drug candidates.
- Contribute to the preparation of regulatory submissions and scientific publications.
- Collaborate with cross-functional teams, including medicinal chemistry, biology, and pharmacology.
- Present research findings at internal meetings and external scientific conferences.
- Stay abreast of the latest scientific literature and technological advancements in the field.
- Provide mentorship and scientific guidance to junior researchers.
- Manage laboratory resources and ensure adherence to safety protocols.
Qualifications:
- Ph.D. in Medicinal Chemistry, Pharmacology, Biochemistry, or a related life science discipline.
- Minimum of 5-7 years of post-doctoral research experience in the pharmaceutical or biotech industry.
- Proven track record of successfully advancing drug candidates through the discovery pipeline.
- Extensive experience in assay development, data analysis, and scientific interpretation.
- Strong knowledge of drug discovery processes and regulatory requirements.
- Excellent written and verbal communication skills.
- Ability to work independently and lead research projects effectively.
- Proficiency in relevant laboratory techniques and instrumentation.
- Demonstrated ability to work collaboratively in a team-oriented research environment.
This challenging and rewarding role is based in our client's cutting-edge facility in Sheffield, South Yorkshire, UK , offering the opportunity to make a significant impact on patient health through innovative pharmaceutical research.
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Senior Research Scientist - Pharmaceutical Development
NG1 1AA Nottingham, East Midlands
£65000 Annually
WhatJobs
Posted 19 days ago
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Job Description
Our client, a pioneering research institution, is seeking an accomplished Senior Research Scientist to contribute to groundbreaking work in pharmaceutical development at their state-of-the-art facility in Nottingham, Nottinghamshire, UK . This role involves leading and executing complex research projects focused on the discovery and development of novel therapeutic agents. You will be responsible for designing experimental protocols, conducting advanced laboratory experiments, analysing data, and interpreting results to drive the drug discovery pipeline forward. This position demands a strong scientific background, exceptional analytical skills, and a proven ability to manage research projects independently.
The ideal candidate will hold a PhD in a relevant scientific discipline (e.g., Pharmacology, Biochemistry, Molecular Biology, Medicinal Chemistry) and possess substantial post-doctoral or industry research experience. Expertise in specific therapeutic areas or cutting-edge research techniques (e.g., high-throughput screening, in vivo pharmacology, bioinformatics) is highly desirable. You should be adept at problem-solving, critical thinking, and troubleshooting experimental challenges. Excellent written and verbal communication skills are essential for preparing research reports, publishing findings, and presenting results to scientific teams and stakeholders. The ability to mentor junior researchers and contribute to a collaborative research environment is also crucial.
Key responsibilities will include:
This is a unique opportunity for a talented Senior Research Scientist to advance their career within a dynamic and forward-thinking research organisation, contributing to the development of life-saving medicines. If you are driven by scientific discovery and possess the expertise to excel in pharmaceutical research, we invite you to apply.
The ideal candidate will hold a PhD in a relevant scientific discipline (e.g., Pharmacology, Biochemistry, Molecular Biology, Medicinal Chemistry) and possess substantial post-doctoral or industry research experience. Expertise in specific therapeutic areas or cutting-edge research techniques (e.g., high-throughput screening, in vivo pharmacology, bioinformatics) is highly desirable. You should be adept at problem-solving, critical thinking, and troubleshooting experimental challenges. Excellent written and verbal communication skills are essential for preparing research reports, publishing findings, and presenting results to scientific teams and stakeholders. The ability to mentor junior researchers and contribute to a collaborative research environment is also crucial.
Key responsibilities will include:
- Leading independent research projects from conception to completion.
- Designing and optimising experimental methodologies and protocols.
- Performing complex laboratory experiments and accurately recording data.
- Analysing and interpreting experimental results using appropriate statistical and computational tools.
- Developing new assays and research techniques.
- Troubleshooting experimental issues and proposing innovative solutions.
- Preparing comprehensive research reports, manuscripts for publication, and patent applications.
- Presenting research findings at scientific conferences and internal meetings.
- Mentoring and guiding junior scientists and research assistants.
- Collaborating with internal and external research partners.
- Staying abreast of the latest scientific literature and technological advancements.
This is a unique opportunity for a talented Senior Research Scientist to advance their career within a dynamic and forward-thinking research organisation, contributing to the development of life-saving medicines. If you are driven by scientific discovery and possess the expertise to excel in pharmaceutical research, we invite you to apply.
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7
Senior Research Scientist - Pharmaceutical Development
S1 2GY Sheffield, Yorkshire and the Humber
£60000 Annually
WhatJobs
Posted 19 days ago
Job Viewed
Job Description
Our client, a renowned pharmaceutical company at the forefront of drug discovery and development, is seeking a highly motivated and experienced Senior Research Scientist to join their innovative R&D team. This vital role is based in our client's state-of-the-art facility in Sheffield, South Yorkshire, UK , and requires an on-site presence to facilitate hands-on laboratory work and close collaboration. You will contribute significantly to the development of novel therapeutic agents.
Responsibilities:
Qualifications:
Responsibilities:
- Design, execute, and interpret complex experiments in areas such as medicinal chemistry, pharmacology, or molecular biology.
- Develop and validate new analytical methods and experimental protocols.
- Analyse and synthesise research data, drawing insightful conclusions and formulating hypotheses.
- Contribute to the identification and characterisation of new drug candidates.
- Prepare detailed scientific reports, manuscripts for publication, and presentations for internal and external audiences.
- Collaborate effectively with cross-functional teams, including chemists, biologists, toxicologists, and clinical scientists.
- Maintain laboratory equipment and ensure compliance with all safety and regulatory guidelines (e.g., GLP, GMP).
- Troubleshoot experimental issues and propose innovative solutions.
- Mentor and guide junior research staff, fostering a collaborative and productive laboratory environment.
- Stay current with scientific literature, emerging technologies, and industry trends relevant to pharmaceutical research.
Qualifications:
- PhD in Chemistry, Pharmacology, Biology, or a closely related scientific discipline.
- Minimum of 5 years of post-doctoral or industry experience in pharmaceutical research and development.
- Demonstrated expertise in a specific area of drug discovery or development (e.g., small molecule synthesis, target validation, assay development, PK/PD studies).
- Proven track record of independent research, including publications in peer-reviewed journals.
- Strong experimental design, data analysis, and critical thinking skills.
- Proficiency with relevant laboratory techniques and instrumentation.
- Excellent written and verbal communication skills, with the ability to present complex scientific information clearly.
- Experience working in a regulated laboratory environment is essential.
- Ability to work collaboratively in a team-oriented setting.
- Strong organisational skills and attention to detail.
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8
Clinical Research Associate (CRA)
DE1 2PB Derby, East Midlands
£40000 Annually
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Posted today
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Job Description
Our client, a leading pharmaceutical company, is seeking a motivated Clinical Research Associate (CRA) to join their growing team. This role plays a critical part in the successful execution of clinical trials, ensuring adherence to protocol, Good Clinical Practice (GCP) guidelines, and regulatory requirements. As a CRA, you will be responsible for monitoring clinical trial sites, verifying the accuracy and completeness of data, and ensuring the safety and rights of trial participants. You will conduct site initiation visits, interim monitoring visits, and close-out visits, providing essential support and oversight to investigators and study staff. Effective communication and relationship-building with site personnel are paramount to this role. You will also be involved in source data verification, regulatory document review, and managing drug accountability. The successful candidate will possess strong organizational skills, meticulous attention to detail, and the ability to work independently and manage their time effectively. While this role requires travel to clinical sites, a hybrid working model is in place, allowing for a balance between remote work and on-site visits. Experience in clinical research is essential, along with a solid understanding of pharmaceutical drug development processes. Join a company that is at the forefront of medical innovation and contribute to bringing life-changing therapies to patients.
Responsibilities:
Responsibilities:
- Monitor assigned clinical trial sites to ensure compliance with study protocols, SOPs, and GCP.
- Verify the accuracy, completeness, and integrity of clinical data through source document review.
- Ensure the safety and rights of study participants are protected.
- Conduct site initiation, routine monitoring, and close-out visits.
- Build and maintain strong working relationships with investigators and site staff.
- Review and approve regulatory documents submitted by study sites.
- Manage drug accountability and investigational product supplies at sites.
- Identify and resolve site-level issues and deviations promptly.
- Train site staff on study-specific procedures and regulatory requirements.
- Prepare and submit accurate monitoring visit reports in a timely manner.
- Bachelor's degree in Life Sciences, Nursing, Pharmacy, or a related field.
- Previous experience as a Clinical Research Associate or in a similar clinical trial monitoring role.
- Thorough understanding of GCP, ICH guidelines, and regulatory requirements.
- Excellent organizational, time management, and problem-solving skills.
- Strong written and verbal communication skills.
- Ability to travel to assigned clinical sites as needed.
- Proficiency in clinical trial management systems (CTMS) and electronic data capture (EDC) systems.
- Detail-oriented with a commitment to data accuracy and patient safety.
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