6,607 Cancer Biology jobs in the United Kingdom
Research Scientist, Cancer Cell Biology
Posted 614 days ago
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About Us
Exscientia is an AI-driven pharmatech company committed to discovering, designing and developing the best possible drugs in the fastest and most effective manner. Exscientia developed the first-ever functional precision oncology platform to successfully guide treatment selection and improve patient outcomes in a prospective interventional clinical study, as well as to progress AI-designed small molecules into the clinical setting.
Our pipeline demonstrates our ability to rapidly translate scientific concepts into precision-designed therapeutic candidates, with more than 15 projects underway. By designing better drugs, faster, we believe the best ideas of science can rapidly become the best medicines for patients.
The Role
We are expanding our in vitro cancer cell biology capabilities at our new state of the art laboratories in Milton Park and are seeking experienced, motivated, and dynamic individuals to join the primary pharmacology team. This team provides critical data driving our drug discovery projects and is in charge of conceiving, developing, and executing cellular assays for a range of target classes, often in areas of novel biology.
Successful applicants will be given the freedom to design, plan and execute a variety of experiments ensuring that the assays are fit-for-purpose, and that data is appropriately quality-controlled. In our newly built laboratories, we have access to a wide array of assay technologies (FRET, luminescence, FACs, imaging) with automation capabilities and are continually striving to deploy the latest technologies and develop ever more efficient processes.
Please note this is an on-site role at our Milton Park site in Oxford, with occasional flexibility to work from home in the UK. We are a flexible working organisation and we’re willing to consider other options which would provide similar contact time with the team.
You will have the opportunity to:
- Develop assays to help drive development of therapeutic small molecules with a focus on compound characterisation and the rapid identification of candidate molecules in the oncology area.
- You will be expected to keep up with the latest scientific developments, evaluate new technologies and will have the opportunity to present both internally and externally.
- This is primarily a laboratory-based positions with scope for continual learning and development and exposure to all scientific disciplines within the drug discovery process from target validation to candidate selection.
Requirements
- Ph.D in Oncology, Biology, Pharmacology, or a related discipline or a BSc/MSc degree with significant relevant experience, preferably in the pharmaceutical or biotechnology industry.
- Sterile techniques and cell culture
- In vitro assay development and assay optimisation
- Experience of cell-based assays such as proliferation, cell binding, cytokine release, and tumour killing
- Practical knowledge of a wide range of assay technologies such as FRET, flow cytometry and imaging
- Experience of screening and data analysis including dose-response relationships
- Flexible, adaptable, and able to work across multiple projects.
- Excellent interpersonal and communication skills, both written and verbal, with ability to communicate technical information to a non-specialist audience.
Benefits
- Join our inclusive, collaborative and intellectually stimulating organisation with strong company values.
- As a learning organisation, we provide access to learning and development opportunities and will place you at the forefront of your career growth at Exscientia.
- We employ brilliant people so we pay highly competitive salaries. Additionally, all our employees are eligible for a company-wide annual bonus and receive both a new joiner and annual share award.
- Enjoy our generous holiday allowance and flexible working approach to find a healthy work-life balance that works for you.
- We’re leading the way in progressive leave, offering enhanced policies such as generous parental leave, surrogacy, menopause, and family emergency leave so you feel supported no matter the life event.
- Additionally, we support childcare costs for children aged 0-5 through our affordable childcare scheme.
- Take advantage of two generous salary exchange schemes to claim discounts on a brand new electric vehicle and cycling equipment worth up to £3,500.
- As a healthcare company, we understand the importance of health and wellbeing so we provide comprehensive private health insurance, dental and vision benefits for you and your family.
- We also provide plenty of access to mental health support including therapy and counselling sessions plus an employee assistance program for help with lifestyle issues such as bereavement, family problems or money management.
- To help safeguard the future for you and your loved ones, we also offer pension and life cover.
- Help yourself to drinks and snacks in our fully stocked kitchens. Join your colleagues in one of our many breakout areas and get to know the people you are working with. Some of the best ideas start with a coffee break!
- Feel inspired in our high spec labs where you will use state-of-the-art equipment and instrumentation that enable you to do your best work.
- We’ll even support your home office environment with an allowance for furniture and equipment to make your space as comfortable and productive as possible.
- Learn more about why our team enjoy working at Exscientia here
Research Scientist - Molecular Biology
Posted 11 days ago
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Key Responsibilities:
- Design, execute, and interpret experiments related to molecular biology, genetics, and cell biology.
- Develop and optimize novel molecular assays and techniques.
- Perform DNA/RNA extraction, PCR, qPCR, cloning, sequencing, and other molecular techniques.
- Maintain meticulous records of experimental procedures, results, and analyses.
- Contribute to the writing of research papers, grant proposals, and scientific presentations.
- Collaborate effectively with cross-functional research teams and external partners.
- Troubleshoot experimental issues and develop solutions.
- Stay abreast of the latest scientific literature and advancements in molecular biology.
- Ensure compliance with all laboratory safety protocols and ethical guidelines.
- Assist in the training and supervision of junior research staff and interns.
- PhD in Molecular Biology, Biochemistry, Genetics, or a related life science field.
- Postdoctoral experience or equivalent research experience in an academic or industry setting.
- Demonstrated expertise in a range of molecular biology techniques (e.g., Next-Generation Sequencing, CRISPR, protein expression).
- Proficiency in data analysis software and statistical methods.
- Proven track record of scientific publication and presentation.
- Excellent problem-solving skills and a critical thinking approach.
- Strong organizational and time management abilities.
- Ability to work independently and collaboratively in a fast-paced research environment.
- Excellent written and verbal communication skills.
- Experience with mammalian cell culture and aseptic techniques is desirable.
Research Scientist - Molecular Biology
Posted 15 days ago
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Research Scientist - Molecular Biology
Posted 18 days ago
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Job Description
The successful candidate will possess a strong foundation in molecular biology principles and hands-on experience with a wide range of experimental techniques. You will be responsible for experimental design, data acquisition, analysis, and interpretation, as well as contributing to the development of new assays and methodologies. Collaboration is key in this role, and you will work closely with colleagues from various scientific disciplines, including biochemistry, cell biology, and pharmacology. The ability to troubleshoot experiments, analyze data rigorously, and effectively communicate findings through reports and presentations is essential. We are looking for a proactive and innovative scientist who is passionate about making a significant contribution to human health.
Key Responsibilities:
- Design, optimize, and perform complex molecular biology experiments to support research objectives.
- Utilize a range of molecular biology techniques, including PCR, qPCR, Western blotting, ELISA, cloning, and cell culture.
- Develop and validate new assays for target identification and validation.
- Analyze and interpret experimental data, drawing conclusions and making recommendations for future experiments.
- Troubleshoot experimental issues and implement solutions to ensure project progression.
- Maintain accurate and detailed experimental records in electronic laboratory notebooks.
- Collaborate effectively with colleagues across different scientific disciplines.
- Contribute to the preparation of research reports, publications, and presentations.
- Stay current with the latest advancements and literature in molecular biology and related fields.
- Contribute to the maintenance and management of laboratory equipment and resources.
- Ph.D. in Molecular Biology, Biochemistry, Genetics, or a related life science field.
- Minimum of 3 years of post-doctoral or industry research experience in molecular biology.
- Proven expertise in a variety of molecular biology techniques, with a strong track record of experimental success.
- Experience with gene editing technologies (e.g., CRISPR) is highly desirable.
- Proficiency in data analysis software and statistical methods.
- Excellent understanding of experimental design principles.
- Strong problem-solving skills and the ability to work independently and as part of a team.
- Excellent written and verbal communication skills.
- A passion for scientific research and a commitment to innovation.
- Experience working in a GLP/GMP environment is a plus.
Principal Research Scientist - Molecular Biology
Posted today
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Responsibilities:
- Design, execute, and interpret complex molecular biology experiments to address key scientific questions.
- Lead research projects from conception through to completion, including experimental design, data analysis, and reporting.
- Develop and optimize novel molecular biology assays and techniques.
- Investigate disease mechanisms and identify potential therapeutic targets.
- Analyze and present research findings at internal meetings and external scientific conferences.
- Author and co-author high-impact publications in peer-reviewed journals.
- Mentor and guide junior research scientists, fostering their scientific development.
- Collaborate effectively with cross-functional teams, including chemists, biologists, and pharmacologists.
- Contribute to the strategic direction of the R&D department.
- Manage laboratory resources and ensure adherence to safety protocols.
- Stay abreast of the latest advancements and literature in molecular biology and related fields.
- Contribute to intellectual property generation and patent filings.
- Ensure meticulous record-keeping and documentation of all research activities.
- Ph.D. in Molecular Biology, Genetics, Biochemistry, or a closely related field.
- Minimum of 8 years of post-doctoral research experience in a relevant scientific setting.
- Demonstrated expertise in a wide range of molecular biology techniques (e.g., PCR, qPCR, Western Blotting, DNA/RNA isolation, cloning, gene editing).
- Proven track record of leading research projects and delivering impactful scientific outcomes.
- Experience in mentoring junior scientists and supervising research projects.
- Strong publication record in reputable scientific journals.
- Excellent analytical, problem-solving, and critical thinking skills.
- Proficiency in data analysis software (e.g., GraphPad Prism, R).
- Outstanding communication and presentation skills, both written and verbal.
- Ability to work independently and collaboratively in a fast-paced research environment.
- Experience with bioinformatics tools and large-scale genomic/transcriptomic data analysis is a plus.
Senior Research Scientist - Molecular Biology
Posted today
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Job Description
Key Responsibilities:
- Design, execute, and troubleshoot complex molecular biology experiments.
- Lead research projects focused on developing novel biological assays and therapeutics.
- Perform molecular biology techniques such as PCR, qPCR, Western blotting, ELISA, and gene cloning.
- Maintain and utilize mammalian cell cultures for experimental purposes.
- Develop and optimize protocols for recombinant protein expression and purification.
- Analyze experimental data using statistical software and interpret results.
- Contribute to the writing of scientific manuscripts, reports, and presentations.
- Collaborate with internal and external research partners.
- Mentor and guide junior research staff and technicians.
- Ensure laboratory compliance with safety regulations and best practices.
- Manage laboratory resources and maintain accurate experimental records.
- Stay current with advancements in molecular biology, genetics, and related fields.
Qualifications:
- Ph.D. in Molecular Biology, Biochemistry, Genetics, or a related life science discipline.
- Minimum of 5 years of postdoctoral or industry research experience in molecular biology.
- Extensive hands-on experience with a wide range of molecular biology techniques.
- Proficiency in data analysis and interpretation using relevant software (e.g., GraphPad Prism, R).
- Experience with CRISPR-Cas9 gene editing, NGS, or flow cytometry is highly advantageous.
- Excellent scientific writing and oral communication skills.
- Demonstrated ability to lead research projects and work effectively in a team.
- Strong problem-solving skills and attention to detail.
- Experience in a pharmaceutical or biotechnology setting is a plus.
- Ability to manage multiple projects simultaneously.
Senior Research Scientist - Molecular Biology
Posted today
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Job Description
Key Responsibilities:
- Design, execute, and interpret complex molecular biology experiments to address key research questions.
- Develop and optimize novel molecular techniques and assays.
- Lead research projects, manage timelines, and mentor junior scientists and research assistants.
- Analyze experimental data using appropriate statistical methods and bioinformatics tools.
- Contribute significantly to the writing of research papers for publication in high-impact peer-reviewed journals.
- Present research findings at national and international scientific conferences.
- Collaborate effectively with internal research teams and external collaborators.
- Maintain comprehensive and accurate laboratory records.
- Ensure compliance with all relevant laboratory safety protocols and ethical guidelines.
- Manage laboratory resources, including equipment, reagents, and supplies.
- Contribute to grant writing efforts to secure funding for new research initiatives.
- Stay abreast of the latest scientific literature and advancements in molecular biology and related fields.
- Troubleshoot experimental challenges and develop innovative solutions.
- PhD in Molecular Biology, Genetics, Biochemistry, or a related life science discipline.
- A minimum of 5-7 years of postdoctoral research experience in a relevant field.
- Demonstrated track record of high-quality research, evidenced by publications in reputable journals.
- Extensive hands-on experience with a wide range of molecular biology techniques (e.g., PCR, qPCR, Western blotting, cloning, gene editing, cell culture, NGS library preparation).
- Proficiency in data analysis software and statistical analysis.
- Experience in (mention specific relevant area, e.g., cancer biology, immunology, neuroscience) is highly desirable.
- Excellent written and oral communication skills.
- Strong leadership, project management, and mentoring abilities.
- Ability to work independently and collaboratively within a research team.
- Familiarity with bioinformatics tools and databases is a plus.
- Willingness to work a hybrid schedule, balancing laboratory work with data analysis and writing from home.
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Senior Research Scientist - Molecular Biology
Posted today
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As a Senior Research Scientist, you will lead and execute complex research projects, focusing on the discovery and validation of novel molecular targets and pathways. You will design and perform in vitro and in vivo experiments, analyze results, and interpret data to drive project progression. Your expertise will be crucial in developing robust experimental methodologies and troubleshooting technical challenges. The role involves significant collaboration with cross-functional teams, including computational biology, pharmacology, and clinical development, to translate scientific findings into tangible advancements.
Key responsibilities will include:
- Designing, optimizing, and executing complex molecular biology experiments (e.g., PCR, qPCR, Western blotting, ELISA, cell culture, gene editing).
- Developing and validating new assays for target identification and drug screening.
- Analyzing and interpreting experimental data, generating high-quality reports, and presenting findings to scientific leadership and project teams.
- Troubleshooting experimental issues and proposing innovative solutions.
- Mentoring and guiding junior scientists and research associates.
- Contributing to the scientific strategy and intellectual property development.
- Staying abreast of the latest scientific literature and technological advancements in molecular biology and related fields.
- Collaborating effectively with internal teams and external partners.
- Ensuring compliance with all laboratory safety and ethical guidelines.
The ideal candidate will possess a PhD in Molecular Biology, Genetics, Biochemistry, or a related life science discipline, coupled with a minimum of 5 years of post-doctoral or industry research experience. A proven track record of successfully leading research projects and publishing in high-impact peer-reviewed journals is essential. Expertise in gene regulation, signaling pathways, and various molecular biology techniques is required. Experience with bioinformatics tools and large-scale data analysis is a significant advantage. Exceptional critical thinking, problem-solving abilities, and strong written and verbal communication skills are paramount. This remote-first position, based in Cardiff, Wales, UK , offers an exceptional opportunity to shape the future of biopharmaceutical research.
Senior Research Scientist - Molecular Biology
Posted today
Job Viewed
Job Description
Qualifications:
- PhD in Molecular Biology, Genetics, Biochemistry, or a related field.
- Minimum of 5 years of relevant post-doctoral or industry research experience.
- Demonstrated expertise in a range of molecular biology techniques.
- Proven experience in assay development and validation.
- Experience with mammalian cell culture and experimental design.
- Strong publication record in peer-reviewed journals.
- Excellent data analysis and interpretation skills.
- Leadership and mentorship capabilities.
- Familiarity with scientific literature databases and research methodologies.
- Ability to work independently and collaboratively in a team setting.
Principal Research Scientist - Molecular Biology
Posted today
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Job Description
Key Responsibilities:
- Design, develop, and execute sophisticated experimental protocols in molecular biology, genetics, and cell biology.
- Lead independent research projects from conceptualization to completion, including hypothesis generation, experimental design, data analysis, and interpretation.
- Supervise and mentor junior research staff, postdoctoral fellows, and students, fostering a collaborative and intellectually stimulating research environment.
- Secure external funding through grant writing and proposal submissions.
- Analyze and interpret complex biological data, employing advanced statistical and bioinformatics tools.
- Author high-impact publications in leading scientific journals and present research findings at international conferences.
- Collaborate with internal and external stakeholders, including industry partners and other academic institutions.
- Ensure compliance with all laboratory safety regulations, ethical guidelines, and institutional policies.
- Manage laboratory resources, including budget, equipment, and consumables.
- Stay abreast of the latest advancements and emerging technologies in molecular biology and related fields.
Qualifications:
- PhD in Molecular Biology, Genetics, Cell Biology, or a closely related discipline.
- A minimum of 10 years of post-doctoral research experience, with a significant track record of independent research and publication in high-impact journals.
- Demonstrated expertise in a specific area of molecular biology (e.g., epigenetics, gene editing, RNA biology, protein interactions).
- Proven success in securing competitive research grants (e.g., NIH, MRC, Wellcome Trust).
- Extensive experience with a wide range of molecular biology techniques (e.g., qPCR, Western blotting, CRISPR, next-generation sequencing, microscopy).
- Strong understanding of bioinformatics and computational biology tools.
- Excellent analytical, critical thinking, and problem-solving skills.
- Outstanding written and verbal communication skills, with the ability to present complex scientific information clearly and concisely.
- Demonstrated leadership abilities and experience in managing research teams.
- Ability to work independently and manage multiple research projects simultaneously in a remote setting.