1,320 Cancer Biology jobs in the United Kingdom
Research Scientist, Cancer Cell Biology
Oxford, South East
Exscientia
Posted 551 days ago
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Job Description
About Us
Exscientia is an AI-driven pharmatech company committed to discovering, designing and developing the best possible drugs in the fastest and most effective manner. Exscientia developed the first-ever functional precision oncology platform to successfully guide treatment selection and improve patient outcomes in a prospective interventional clinical study, as well as to progress AI-designed small molecules into the clinical setting.
Our pipeline demonstrates our ability to rapidly translate scientific concepts into precision-designed therapeutic candidates, with more than 15 projects underway. By designing better drugs, faster, we believe the best ideas of science can rapidly become the best medicines for patients.
The Role
We are expanding our in vitro cancer cell biology capabilities at our new state of the art laboratories in Milton Park and are seeking experienced, motivated, and dynamic individuals to join the primary pharmacology team. This team provides critical data driving our drug discovery projects and is in charge of conceiving, developing, and executing cellular assays for a range of target classes, often in areas of novel biology.
Successful applicants will be given the freedom to design, plan and execute a variety of experiments ensuring that the assays are fit-for-purpose, and that data is appropriately quality-controlled. In our newly built laboratories, we have access to a wide array of assay technologies (FRET, luminescence, FACs, imaging) with automation capabilities and are continually striving to deploy the latest technologies and develop ever more efficient processes.
Please note this is an on-site role at our Milton Park site in Oxford, with occasional flexibility to work from home in the UK. We are a flexible working organisation and we’re willing to consider other options which would provide similar contact time with the team.
You will have the opportunity to:
- Develop assays to help drive development of therapeutic small molecules with a focus on compound characterisation and the rapid identification of candidate molecules in the oncology area.
- You will be expected to keep up with the latest scientific developments, evaluate new technologies and will have the opportunity to present both internally and externally.
- This is primarily a laboratory-based positions with scope for continual learning and development and exposure to all scientific disciplines within the drug discovery process from target validation to candidate selection.
Requirements
- Ph.D in Oncology, Biology, Pharmacology, or a related discipline or a BSc/MSc degree with significant relevant experience, preferably in the pharmaceutical or biotechnology industry.
- Sterile techniques and cell culture
- In vitro assay development and assay optimisation
- Experience of cell-based assays such as proliferation, cell binding, cytokine release, and tumour killing
- Practical knowledge of a wide range of assay technologies such as FRET, flow cytometry and imaging
- Experience of screening and data analysis including dose-response relationships
- Flexible, adaptable, and able to work across multiple projects.
- Excellent interpersonal and communication skills, both written and verbal, with ability to communicate technical information to a non-specialist audience.
Benefits
- Join our inclusive, collaborative and intellectually stimulating organisation with strong company values.
- As a learning organisation, we provide access to learning and development opportunities and will place you at the forefront of your career growth at Exscientia.
- We employ brilliant people so we pay highly competitive salaries. Additionally, all our employees are eligible for a company-wide annual bonus and receive both a new joiner and annual share award.
- Enjoy our generous holiday allowance and flexible working approach to find a healthy work-life balance that works for you.
- We’re leading the way in progressive leave, offering enhanced policies such as generous parental leave, surrogacy, menopause, and family emergency leave so you feel supported no matter the life event.
- Additionally, we support childcare costs for children aged 0-5 through our affordable childcare scheme.
- Take advantage of two generous salary exchange schemes to claim discounts on a brand new electric vehicle and cycling equipment worth up to £3,500.
- As a healthcare company, we understand the importance of health and wellbeing so we provide comprehensive private health insurance, dental and vision benefits for you and your family.
- We also provide plenty of access to mental health support including therapy and counselling sessions plus an employee assistance program for help with lifestyle issues such as bereavement, family problems or money management.
- To help safeguard the future for you and your loved ones, we also offer pension and life cover.
- Help yourself to drinks and snacks in our fully stocked kitchens. Join your colleagues in one of our many breakout areas and get to know the people you are working with. Some of the best ideas start with a coffee break!
- Feel inspired in our high spec labs where you will use state-of-the-art equipment and instrumentation that enable you to do your best work.
- We’ll even support your home office environment with an allowance for furniture and equipment to make your space as comfortable and productive as possible.
- Learn more about why our team enjoy working at Exscientia here
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Research Scientist - Molecular Biology
NR4 7TJ Norwich, Eastern
£38000 Annually
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Our client, a cutting-edge scientific research institution dedicated to groundbreaking discoveries, is seeking an ambitious and skilled Research Scientist specializing in Molecular Biology to contribute to their vital work. Based at the forefront of scientific innovation, this role offers the opportunity to conduct advanced research and contribute to significant advancements in our understanding of biological processes.
Responsibilities:
Qualifications:
This role is a fully remote position, supporting research initiatives impacting fields connected to Norwich, Norfolk, UK .
Responsibilities:
- Design and conduct complex molecular biology experiments using a variety of techniques, including PCR, qPCR, Western blotting, ELISA, and cell culture.
- Analyze experimental data using appropriate statistical and bioinformatics tools.
- Interpret results and develop hypotheses for further investigation.
- Maintain detailed and accurate laboratory notebooks and records of all experiments performed.
- Prepare manuscripts for publication in peer-reviewed scientific journals and present findings at scientific conferences.
- Collaborate with other researchers, technicians, and principal investigators to achieve project goals.
- Develop and optimize new experimental protocols and methodologies.
- Manage and maintain laboratory equipment and ensure compliance with safety regulations.
- Contribute to grant writing and proposal development.
- Train and mentor junior research staff and students on laboratory techniques and procedures.
- Stay up-to-date with the latest literature and advancements in the field of molecular biology.
- Troubleshoot experimental problems and devise creative solutions.
- Contribute to the overall strategy and direction of research projects.
- Ensure all research activities are conducted in an ethical and responsible manner.
Qualifications:
- PhD in Molecular Biology, Biochemistry, Genetics, or a closely related field.
- Postdoctoral experience or equivalent research experience is highly desirable.
- Proven track record of successfully designing and executing complex experiments in molecular biology.
- Extensive hands-on experience with a broad range of molecular biology techniques.
- Strong understanding of cellular and molecular mechanisms.
- Proficiency in data analysis software (e.g., GraphPad Prism, R, Python) and bioinformatics tools.
- Excellent scientific writing and presentation skills.
- Ability to work independently and as part of a collaborative research team.
- Strong problem-solving abilities and attention to detail.
- Familiarity with Good Laboratory Practice (GLP) or Good Manufacturing Practice (GMP) is a plus.
- Experience in project management and supervising junior researchers is advantageous.
- Published research in reputable scientific journals.
- Passion for scientific discovery and a commitment to high-quality research.
This role is a fully remote position, supporting research initiatives impacting fields connected to Norwich, Norfolk, UK .
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Postdoctoral Research Scientist - Molecular Biology
RG1 1LY Reading, South East
£45000 Annually
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Our client, a leading research institution, is seeking an exceptional Postdoctoral Research Scientist to join their cutting-edge Scientific Research & Development department in Reading, Berkshire, UK . This laboratory-based position is integral to groundbreaking projects focused on understanding fundamental biological mechanisms and developing novel therapeutic interventions.
The successful candidate will conduct advanced experiments, analyse complex datasets, and contribute to the publication of research findings in high-impact scientific journals. Responsibilities include designing and executing experiments in molecular biology, biochemistry, and cell biology; culturing mammalian cells; performing genetic manipulations; analysing protein expression and function; and maintaining meticulous laboratory records. You will also be expected to present research findings at scientific conferences and contribute to grant writing.
Key responsibilities include:
The successful candidate will conduct advanced experiments, analyse complex datasets, and contribute to the publication of research findings in high-impact scientific journals. Responsibilities include designing and executing experiments in molecular biology, biochemistry, and cell biology; culturing mammalian cells; performing genetic manipulations; analysing protein expression and function; and maintaining meticulous laboratory records. You will also be expected to present research findings at scientific conferences and contribute to grant writing.
Key responsibilities include:
- Designing, implementing, and troubleshooting complex experiments in molecular and cellular biology.
- Investigating cellular signaling pathways and molecular interactions.
- Utilizing techniques such as PCR, Western blotting, ELISA, immunofluorescence, and flow cytometry.
- Performing gene editing techniques (e.g., CRISPR-Cas9) and analyzing the results.
- Maintaining and culturing primary and immortalized cell lines.
- Analyzing and interpreting experimental data using statistical methods and bioinformatics tools.
- Writing and preparing manuscripts for publication in peer-reviewed journals.
- Presenting research findings at national and international scientific meetings.
- Collaborating with other researchers and contributing to a positive and productive lab environment.
- Ensuring compliance with laboratory safety protocols and ethical guidelines.
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2
Principal Research Scientist - Molecular Biology
PL1 2BN Plymouth, South West
£60000 Annually
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Our client, a leading bioscience research organization, is looking for a distinguished Principal Research Scientist to spearhead groundbreaking work in molecular biology. This hybrid role, based in our state-of-the-art facilities in **Plymouth, Devon**, offers a dynamic blend of laboratory-based research and flexible remote working. You will be responsible for designing and executing complex experimental protocols, analyzing and interpreting data, and contributing significantly to the development of novel therapeutic strategies. The ideal candidate will possess a PhD in Molecular Biology, Genetics, or a related field, with extensive post-doctoral experience and a strong publication record. Your expertise should span various molecular biology techniques, including gene editing, protein expression analysis, and advanced microscopy. You will lead a team of talented researchers, providing mentorship and guidance to foster a collaborative and innovative research environment. Key responsibilities include developing research proposals, securing funding, managing laboratory resources, and ensuring compliance with all safety and ethical guidelines. You will also be expected to present findings at international conferences and contribute to peer-reviewed publications. The ability to think critically, solve complex scientific problems, and communicate research effectively, both verbally and in writing, is crucial. This position offers a unique opportunity to advance scientific knowledge and contribute to cutting-edge research that has the potential to impact human health significantly. We are seeking a visionary scientist who is passionate about discovery and driven by a desire to push the boundaries of molecular biology. Your contributions will be vital in shaping the future direction of our research programs.
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3
Senior Research Scientist - Molecular Biology
NG1 3FE Nottingham, East Midlands
£55000 Annually
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Our client is seeking a highly skilled and motivated Senior Research Scientist to join their dynamic R&D team based in **Nottingham, Nottinghamshire, UK**. This role is pivotal in driving forward innovative projects within the field of molecular biology. The successful candidate will be responsible for designing, executing, and analyzing complex experiments, contributing to the development of novel therapeutic agents. Key responsibilities include leading research initiatives, mentoring junior scientists, developing and validating new assays, and troubleshooting experimental protocols. You will be expected to interpret data, generate comprehensive reports, and present findings to internal stakeholders and at scientific conferences. This position requires a deep understanding of molecular biology techniques, including PCR, qPCR, Western blotting, ELISA, cell culture, and gene editing technologies (e.g., CRISPR). A strong background in bioinformatics and data analysis is also essential.
The ideal candidate will possess a PhD in Molecular Biology, Biochemistry, Genetics, or a related life science discipline, with a minimum of 5 years of post-doctoral research experience in an industry or academic setting. Proven experience in leading research projects and a track record of publications in peer-reviewed journals are crucial. Excellent communication, problem-solving, and teamwork skills are mandatory. This is an opportunity to work in a cutting-edge research environment with state-of-the-art facilities and collaborate with leading experts in the field. The role involves a hybrid working model, blending on-site laboratory work with remote collaboration and data analysis.
We are looking for an individual with a passion for scientific discovery, meticulous attention to detail, and the ability to work independently as well as part of a multidisciplinary team. If you are a driven scientist looking to make a significant impact in groundbreaking research, we encourage you to apply. This role offers competitive remuneration and excellent career progression opportunities within a leading scientific organisation.
The ideal candidate will possess a PhD in Molecular Biology, Biochemistry, Genetics, or a related life science discipline, with a minimum of 5 years of post-doctoral research experience in an industry or academic setting. Proven experience in leading research projects and a track record of publications in peer-reviewed journals are crucial. Excellent communication, problem-solving, and teamwork skills are mandatory. This is an opportunity to work in a cutting-edge research environment with state-of-the-art facilities and collaborate with leading experts in the field. The role involves a hybrid working model, blending on-site laboratory work with remote collaboration and data analysis.
We are looking for an individual with a passion for scientific discovery, meticulous attention to detail, and the ability to work independently as well as part of a multidisciplinary team. If you are a driven scientist looking to make a significant impact in groundbreaking research, we encourage you to apply. This role offers competitive remuneration and excellent career progression opportunities within a leading scientific organisation.
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4
Principal Research Scientist - Molecular Biology
W1A 0AX London, London
£70000 Annually
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Join our innovative research team as a Principal Research Scientist specializing in Molecular Biology, operating entirely remotely. This senior position is crucial for driving cutting-edge research and development in our state-of-the-art laboratories. You will lead independent research projects, conceptualize and execute complex experimental designs, and interpret intricate molecular and cellular data. Your responsibilities will include developing novel assays, optimizing existing methodologies, and contributing to the advancement of our scientific pipeline. You will also be responsible for mentoring junior scientists, preparing manuscripts for publication in high-impact journals, and presenting research findings at international conferences. A Ph.D. in Molecular Biology, Genetics, Biochemistry, or a related field is mandatory, along with a minimum of 8 years of post-doctoral research experience, demonstrating a strong publication record and expertise in advanced molecular techniques. Proven experience in leading research projects and managing scientific teams is essential. Proficiency in a range of molecular biology techniques, including PCR, qPCR, Western blotting, cloning, gene editing (e.g., CRISPR), and mammalian cell culture, is required. Experience with bioinformatics tools and data analysis software is also highly beneficial. This remote-first opportunity allows you to contribute significantly to groundbreaking scientific discoveries while enjoying the flexibility of working from home. We are looking for a highly motivated, scientifically rigorous individual with exceptional problem-solving abilities and a passion for pushing the boundaries of scientific knowledge. Collaboration across multidisciplinary teams is key, and you will be expected to communicate complex scientific concepts effectively. This is an unparalleled chance to make a significant impact on our understanding of biological systems and develop novel therapeutic strategies. Your leadership will be instrumental in shaping the future direction of our molecular biology research.
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5
Lead Research Scientist - Molecular Biology
NE1 1AA Newcastle upon Tyne, North East
£60000 Annually
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Our client, a pioneering biotechnology firm in Newcastle upon Tyne, Tyne and Wear, UK , is seeking an accomplished Lead Research Scientist specializing in Molecular Biology to spearhead innovative research projects. This critical role involves designing and executing complex experiments, analyzing data, and interpreting results to advance our understanding of cellular mechanisms and disease pathways. You will be responsible for leading a team of talented scientists, providing scientific direction, mentorship, and ensuring the successful progression of research pipelines. Key responsibilities include developing novel molecular assays, optimizing existing protocols, and troubleshooting experimental challenges. You will also be expected to stay abreast of the latest scientific literature and technological advancements in the field, contributing to the company's intellectual property through publications and patent applications. The ideal candidate will possess a PhD in Molecular Biology, Genetics, or a related life science discipline, with a minimum of 6-8 years of post-doctoral research experience, including significant experience in a leadership or supervisory capacity. Demonstrated expertise in techniques such as PCR, qPCR, Western blotting, ELISA, gene cloning, and sequencing is essential. Experience with bioinformatics tools and data analysis is highly desirable. Strong project management skills, excellent problem-solving abilities, and outstanding written and verbal communication skills are required for this position. This role offers a hybrid working model, combining laboratory-based research with remote data analysis, report writing, and collaboration. Join a dynamic and collaborative research environment dedicated to making significant contributions to human health.
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6
Principal Research Scientist - Molecular Biology
CB2 1LA Cambridge, Eastern
£65000 Annually
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Our client, a world-renowned bioscience research institution, is seeking an exceptional Principal Research Scientist with a specialization in Molecular Biology to join their cutting-edge facility in Cambridge. This demanding role is critical to advancing our understanding of complex biological systems and developing innovative solutions for unmet medical needs. You will lead independent research projects, mentor junior scientists, and contribute to grant writing and funding applications. Responsibilities include designing and executing complex experimental protocols, analyzing and interpreting large datasets, and presenting findings at international conferences. A significant portion of your time will be dedicated to developing novel molecular techniques and assays, validating new targets, and contributing to the strategic direction of the research group. The ideal candidate will possess a PhD in Molecular Biology, Biochemistry, Genetics, or a closely related field, with a minimum of 7-10 years of post-doctoral research experience in an academic or industry setting. A strong publication record in high-impact peer-reviewed journals is essential. Proven leadership abilities, excellent problem-solving skills, and the capacity to manage multiple projects concurrently are required. Experience in project management, including budget oversight and team coordination, is highly advantageous. This position offers the opportunity to work with state-of-the-art equipment and collaborate with leading experts in the field. Candidates should demonstrate a deep theoretical knowledge of molecular mechanisms and practical expertise in a broad range of molecular biology techniques, including gene editing, protein expression analysis, and next-generation sequencing. The ability to think critically, creatively, and independently is paramount. This is a challenging but rewarding role for a highly motivated and ambitious scientist.
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7
Senior Research Scientist - Molecular Biology
NE2 1RQ Newcastle upon Tyne, North East
£65000 Annually
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Our client is a leading R&D organization seeking a highly motivated and experienced Senior Research Scientist specializing in Molecular Biology to join their state-of-the-art facility in **Newcastle upon Tyne**. This role requires hands-on laboratory work and a deep understanding of cutting-edge molecular techniques. You will be instrumental in designing and executing complex research projects, contributing to groundbreaking discoveries, and mentoring junior researchers. The focus will be on innovative approaches to disease mechanisms and therapeutic interventions.
Responsibilities:
Responsibilities:
- Design, plan, and conduct sophisticated experiments in molecular biology, cell biology, and related disciplines.
- Develop and validate novel molecular assays and techniques.
- Analyze and interpret complex biological data, preparing comprehensive reports and presentations.
- Troubleshoot experimental challenges and optimize protocols.
- Collaborate with interdisciplinary teams to advance research projects from bench to potential applications.
- Stay current with the latest scientific literature and technological advancements in the field.
- Supervise and mentor junior scientists and research assistants, providing technical guidance and training.
- Contribute to the writing of grant proposals and scientific publications.
- Present research findings at national and international scientific conferences.
- Ensure all laboratory activities comply with safety regulations and ethical guidelines.
- Ph.D. in Molecular Biology, Biochemistry, Genetics, or a closely related field.
- Minimum of 5 years of post-doctoral or industry research experience.
- Extensive hands-on experience with a wide range of molecular biology techniques (e.g., PCR, qPCR, Western blotting, gene cloning, CRISPR, next-generation sequencing).
- Proven track record of successfully managing research projects and delivering results.
- Strong understanding of statistical analysis and data interpretation.
- Excellent scientific writing and presentation skills.
- Demonstrated ability to lead and mentor research staff.
- Proficiency in scientific software and databases.
- Ability to work independently and collaboratively in a fast-paced research environment.
- Experience with assay development and validation is highly desirable.
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8
Senior Research Scientist - Molecular Biology
MK1 1AA Milton Keynes, South East
£65000 Annually
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Our client is looking for an exceptional Senior Research Scientist specializing in Molecular Biology to join their cutting-edge R&D department. This is a fully remote position, offering the flexibility to work from anywhere within the UK. The role will focus on advancing our understanding of cellular mechanisms and developing novel therapeutic targets. You will lead research projects from conceptualization to data analysis and publication, designing and executing complex experiments, and interpreting results. Key responsibilities include developing and validating new molecular assays, utilizing advanced techniques such as CRISPR gene editing, next-generation sequencing (NGS), and various omics technologies. You will be expected to stay abreast of the latest scientific literature and technological advancements in the field. Collaboration with an international team of scientists, bioinformaticians, and clinicians will be essential, requiring strong communication and teamwork skills. The successful candidate will mentor junior researchers, contribute to grant writing, and present findings at scientific conferences. A PhD in Molecular Biology, Biochemistry, Genetics, or a related discipline is required, along with a proven track record of independent research and publications in peer-reviewed journals. Experience with pipeline development and a deep understanding of drug discovery processes are highly desirable. This is a unique opportunity to contribute to groundbreaking research in a remote-first environment, making a significant impact on the future of medicine. The ideal candidate is a self-starter, highly organized, and possesses excellent critical thinking and problem-solving abilities. Familiarity with statistical software for data analysis and a strong understanding of regulatory requirements in preclinical research are also beneficial.
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