61 Clinical Development jobs in the United Kingdom

PE Global is currently recruiting for a Clinical Development Director (Neurology) for an 18 month contract role with a leading multinational Pharma client based in London – hybrid.

The Clinical Development Director (CDD) is the clinical/scientific and clinical development expert and provides leadership and support to clinical development deliverables and activities within a defined global clinical development program and/or global clinical trial (e.g. clinical development plan, clinical trial protocol), under the leadership of the GPCH.

Job Responsibilities

• Supports and if assigned leads delivery of all assigned clinical deliverables in the assigned section of a clinical program.
• Provides input into final analyses and interpretation including the development of the Clinical Study Report(s) (CSRs), publications and internal/external presentations.
• Leads development of clinical sections of trial and program level regulatory documents (e.g., Investigator’s Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities)
• Oversees/conducts ongoing clinical and scientific review of clinical trial data with medical monitor, Clinical Scientific Expert(s) with appropriate oversight from Medical Lead.
• Inspection Readiness and interaction with QA - risk assessments, audit preparation, mock interviews, storyboard and presentation prep; Author and/or review abstracts, presentations and manuscripts for accuracy of clinical data and content
• Provides support to Sr CDMD and/or GPCH in monitoring and safety data and signals the molecule for the assigned section of the clinical trial, may be a member of the Safety Management Team (SMT), and supports overall program safety reporting (e.g., Periodic Safety Update Reports (PSURs), Drug Safety Update Reports (DSURs), and other safety related documents) in collaboration with the medical monitor, CDMD and Patient Safety
• Ensures career development of Program reports and other clinical colleagues through active participation in the performance management and talent planning processes. Provides on-boarding, training, & mentoring support.
• Contributes to medical/scientific training of relevant stakeholders on the disease area and compound/molecule. May serve as speaker for franchise medical/scientific training
• May be assigned to lead clinical trial(s) as Clinical Scientific Lead and provide leadership and guidance for all clinical aspects of a clinical trial in close collaboration with the assigned medical monitor and/or CDMD.

Requirements

• PhD in Neuroscience (or similar)
• Experience in Neuroscience, Cell & Gene, Neurodegeneration, Rare or neuromuscular diseases, or Neuroinflammation (preferred).
• Preferred experience in Multiple Sclerosis, Huntington's Disease, Myasthenia Gravis, or similar conditions.
• Clinical Development Experience - Required - i.e. protocol and protocol documentation development
• Clinical Data Review Experience - ESSENTIAL: Oversees/conducts ongoing clinical and scientific review of clinical trial data with medical monitor, Clinical Scientific Expert(s) with appropriate oversight from Medical Lead. Work in close collaboration with the data management and statistics teams to ensure proper data quality and analysis of clinical trial results.
• At least 5 years or more in role of (or similar to) Clinical Development Director
• ≥ 7 years of involvement in clinical research or drug development in an academic or industry environment spanning clinical activities in Phases I through IV.
• ≥ 3 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry.

Interested candidates should submit an updated CV.

***Please note our client cannot assist with any visa sponsorship and candidates must have the correct visa to live and work in UK***

Director – Clinical Development // Develop the next Ophthalmology blockbuster // Remote

You are an experienced in clinical development and have a strong expertise in back of the eye diseases.

Why have you dedicated your career to the clinic? To develop new drugs meeting real unmet need for patients?

We are working with an Italian pharma who specialise in developing drugs for rare and complex diseases within the ophthalmology, CNS, and immunology. A private company with significant resources, a long-term view, a dynamic, fast-paced mindset, and a real track record of success. They are looking for a Director Clinical Development to drive an Ophthalmology growth-factor which has best-in-class potential (and has been awarded an FDA voucher after incredible preclinical data for a rare disease) from phase I through IV.

You will lead significant projects in a very important program (which you will co-lead), have strategic input, and significant influence over the direction of ophthalmology clinical development. You will join a world class team that has already taken ophthalmology drugs to market and have a real impact on the team’s ability to become even more successful.

If you are an industrial (CRO, pharma, biotech) expert in clinical development with experience in ophthalmology (back of eye diseases), ready to revolutionise patient care within ophthalmology, apply here or reach out to

We look forward to hearing from you.

Job title: Clinical Development Director (Neurology / Cardio / Immunology)

Location: Remote

Contract duration: 18 months (possibility of extension)

Pay rate: 700 GBP per day via Umbrella

Note: Candidate can be from United Kingdom or Ireland.

Job Purpose:

The Clinical Development Director (CDD) is the clinical/scientific and clinical development expert and provides leadership and support to clinical development deliverables and activities within a defined global clinical development program and/or global clinical trial (e.g. clinical development plan, clinical trial protocol), under the leadership of the GPCH.

Major Activities:

1. Supports and if assigned leads delivery of all assigned clinical deliverables in the assigned section of a clinical program. Clinical deliverables may include the

clinical development strategy for assigned program section(s), clinical sections of individual protocols consistent with the Integrated Development Plans (IDP),

clinical data review and program specific standards, clinical components of regulatory documents/registration dossiers, and publications.

2. Provides input into final analyses and interpretation including the development of the Clinical Study Report(s) (CSRs), publications and internal/external presentations.

3. Leads development of clinical sections of trial and program level regulatory documents (e.g., Investigator's Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities).

4. Oversees/conducts ongoing clinical and scientific review of clinical trial data with medical monitor, Clinical Scientific Expert(s) with appropriate oversight from Medical Lead. Work in close collaboration with the data management and statistics teams to ensure proper data quality and analysis of clinical trial results.

5. Inspection Readiness and interaction with QA - risk assessments, audit preparation, mock interviews, storyboard and presentation prep; Author and/or review abstracts, presentations and manuscripts for accuracy of clinical data and content.

6. May be the Program Manager of other associates (e.g., CSE).

7. Provides support to Sr CDMD and/or GPCH in monitoring and safety data and signals the molecule for the assigned section of the clinical trial, may be a member of the Safety Management Team (SMT), and supports overall program safety reporting (e.g., Periodic Safety Update Reports (PSURs), Drug Safety Update Reports (DSURs), and other safety related documents) in collaboration with the medical monitor, CDMD and Patient Safety.

8. As a clinical development expert, may support the GPCH or CDH in interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data

monitoring boards, advisory boards, patient advocacy groups), internal stakeholders (e.g., CTT, Research, Translational Medicine, Global Medical Affairs, Marketing, HE&OR), and internal decision boards.

9. May work with Biomedical Research/Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with Client&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as assigned.

10. Ensures career development of Program reports and other clinical colleagues through active participation in the performance management and talent planning processes. Provides on-boarding, training, & mentoring support.

11. Contributes to medical/scientific training of relevant Client stakeholders on the disease area and compound/molecule. May serve as speaker for franchise medical/scientific training.

12. May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives).

13. May be assigned to lead clinical trial(s) as Clinical Scientific Lead and provide leadership and guidance for all clinical aspects of a clinical trial in close

collaboration with the assigned medical monitor and/or CDMD.

KPIs:

• Timely delivery of high quality IDP/CDP sections, CTPs, and other clinical deliverables aligned with IDP/CDP and TPP and endorsed by review committees and internal boards, with acceptance by key external and internal stakeholders

• Applies effective clinical research methodology, including trial design/analyses, efficacy endpoints, safety assessments, and risk management across disease area and development phases

• Strong evidence of quality clinical/scientific review of trial data; lead TA through high quality IDP and protocol reviews; timely development of quality disease/program clinical standards, publications, internal/external presentations, and other CD deliverables

• Strong evidence of quality contributions to and acceptance of clinical sections of regulatory documents, Investigators' Brochures, briefing books, safety updates,

and submission dossiers by key external and internal stakeholders

• Well managed, effective, and engaged clinical teams; demonstrated ability to deputize for GPCH at GCT, as well as other venues as needed

• Clearly demonstrates Client Values and Behaviors

Experience required:

• 7 years of involvement in clinical research or drug development in an academic or industry environment spanning clinical activities in Phases I through IV. 3 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry.

• Advanced knowledge of assigned therapeutic area

• Demonstrated ability to establish strong scientific partnership with key stakeholders

• Thorough knowledge of GCP, clinical trial design and methodology, statistical analysis methodology, and regulatory/clinical development process

• 1 year of People management experience preferred this may include management in a matrix environment.

CPL Life Sciences are partnering with one of our long standing clients, a well-reputable global pharma, who are seeking a number of experienced Clinical Development Directors to provide strategic and scientific leadership across a range of their global clinical development programs in neurology, immunology, and cardiology . The role spans all phases of clinical research, from early to late phase.

• 18 month contract
• Fully remote
• £700 per day (Umbrella)

The successful individuals will oversee clinical strategy, protocol development, data interpretation, and contribute to regulatory interactions and documentation. The role requires cross-functional collaboration across data management, biostatistics, medical affairs, and regulatory functions. The successful candidate will also support inspection readiness, audit preparation, and stakeholder engagement (e.g., advisory boards, regulatory agencies, KOLs).

This is not a clinical operations position, and is instead responsible for the scientific input and clinical development progress of the current live studies. This will be in close collaboration with a wider development team.

Key Experience:

• Experience in one or more of; neurology, immunology, or cardiovascular indications
• Authoring and reviewing clinical trial protocols, investigator brochures, and study reports
• Oversight of medical monitoring and clinical data review activities
• Experience in contributing to global regulatory submissions and responses
• Strong background in safety data evaluation, risk management, and benefit-risk assessments
• Collaboration with cross-functional study teams and external stakeholders (e.g., CROs, regulatory bodies)
• Strategic input into clinical development plans and translational strategies
• Familiarity with inspection readiness, GCP audits, and regulatory compliance
• Development of publication strategies and review of scientific communications
• Ability to lead, mentor, and develop clinical team members within a matrix environment
• No line management required.
• Masters or PHD is preferable, but not essential

This is an excellent opportunity for an experienced clinical leader to make a significant impact within high-priority therapeutic areas and help shape the future of innovative treatments.

CPL Life Sciences are partnering with one of our long standing clients, a well-reputable global pharma, who are seeking a number of experienced Clinical Development Directors to provide strategic and scientific leadership across a range of their global clinical development programs in neurology, immunology, and cardiology . The role spans all phases of clinical research, from early to late phase.

• 18 month contract
• Fully remote
• £700 per day (Umbrella)

The successful individuals will oversee clinical strategy, protocol development, data interpretation, and contribute to regulatory interactions and documentation. The role requires cross-functional collaboration across data management, biostatistics, medical affairs, and regulatory functions. The successful candidate will also support inspection readiness, audit preparation, and stakeholder engagement (e.g., advisory boards, regulatory agencies, KOLs).

This is not a clinical operations position, and is instead responsible for the scientific input and clinical development progress of the current live studies. This will be in close collaboration with a wider development team.

Key Experience:

• Experience in one or more of; neurology, immunology, or cardiovascular indications
• Authoring and reviewing clinical trial protocols, investigator brochures, and study reports
• Oversight of medical monitoring and clinical data review activities
• Experience in contributing to global regulatory submissions and responses
• Strong background in safety data evaluation, risk management, and benefit-risk assessments
• Collaboration with cross-functional study teams and external stakeholders (e.g., CROs, regulatory bodies)
• Strategic input into clinical development plans and translational strategies
• Familiarity with inspection readiness, GCP audits, and regulatory compliance
• Development of publication strategies and review of scientific communications
• Ability to lead, mentor, and develop clinical team members within a matrix environment
• No line management required.
• Masters or PHD is preferable, but not essential

This is an excellent opportunity for an experienced clinical leader to make a significant impact within high-priority therapeutic areas and help shape the future of innovative treatments.

PE Global is currently recruiting for a Clinical Development Director (Neurology) for an 18 month contract role with a leading multinational Pharma client based in London – hybrid.

The Clinical Development Director (CDD) is the clinical/scientific and clinical development expert and provides leadership and support to clinical development deliverables and activities within a defined global clinical development program and/or global clinical trial (e.g. clinical development plan, clinical trial protocol), under the leadership of the GPCH.

Job Responsibilities

• Supports and if assigned leads delivery of all assigned clinical deliverables in the assigned section of a clinical program.
• Provides input into final analyses and interpretation including the development of the Clinical Study Report(s) (CSRs), publications and internal/external presentations.
• Leads development of clinical sections of trial and program level regulatory documents (e.g., Investigator’s Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities)
• Oversees/conducts ongoing clinical and scientific review of clinical trial data with medical monitor, Clinical Scientific Expert(s) with appropriate oversight from Medical Lead.
• Inspection Readiness and interaction with QA - risk assessments, audit preparation, mock interviews, storyboard and presentation prep; Author and/or review abstracts, presentations and manuscripts for accuracy of clinical data and content
• Provides support to Sr CDMD and/or GPCH in monitoring and safety data and signals the molecule for the assigned section of the clinical trial, may be a member of the Safety Management Team (SMT), and supports overall program safety reporting (e.g., Periodic Safety Update Reports (PSURs), Drug Safety Update Reports (DSURs), and other safety related documents) in collaboration with the medical monitor, CDMD and Patient Safety
• Ensures career development of Program reports and other clinical colleagues through active participation in the performance management and talent planning processes. Provides on-boarding, training, & mentoring support.
• Contributes to medical/scientific training of relevant stakeholders on the disease area and compound/molecule. May serve as speaker for franchise medical/scientific training
• May be assigned to lead clinical trial(s) as Clinical Scientific Lead and provide leadership and guidance for all clinical aspects of a clinical trial in close collaboration with the assigned medical monitor and/or CDMD.

Requirements

• PhD in Neuroscience (or similar)
• Experience in Neuroscience, Cell & Gene, Neurodegeneration, Rare or neuromuscular diseases, or Neuroinflammation (preferred).
• Preferred experience in Multiple Sclerosis, Huntington's Disease, Myasthenia Gravis, or similar conditions.
• Clinical Development Experience - Required - i.e. protocol and protocol documentation development
• Clinical Data Review Experience - ESSENTIAL: Oversees/conducts ongoing clinical and scientific review of clinical trial data with medical monitor, Clinical Scientific Expert(s) with appropriate oversight from Medical Lead. Work in close collaboration with the data management and statistics teams to ensure proper data quality and analysis of clinical trial results.
• At least 5 years or more in role of (or similar to) Clinical Development Director
• ≥ 7 years of involvement in clinical research or drug development in an academic or industry environment spanning clinical activities in Phases I through IV.
• ≥ 3 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry.

Interested candidates should submit an updated CV.

***Please note our client cannot assist with any visa sponsorship and candidates must have the correct visa to live and work in UK***

PE Global is currently recruiting for a Clinical Development Director (Neurology) for an 18 month contract role with a leading multinational Pharma client based in London – hybrid.

The Clinical Development Director (CDD) is the clinical/scientific and clinical development expert and provides leadership and support to clinical development deliverables and activities within a defined global clinical development program and/or global clinical trial (e.g. clinical development plan, clinical trial protocol), under the leadership of the GPCH.

Job Responsibilities

• Supports and if assigned leads delivery of all assigned clinical deliverables in the assigned section of a clinical program.
• Provides input into final analyses and interpretation including the development of the Clinical Study Report(s) (CSRs), publications and internal/external presentations.
• Leads development of clinical sections of trial and program level regulatory documents (e.g., Investigator’s Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities)
• Oversees/conducts ongoing clinical and scientific review of clinical trial data with medical monitor, Clinical Scientific Expert(s) with appropriate oversight from Medical Lead.
• Inspection Readiness and interaction with QA - risk assessments, audit preparation, mock interviews, storyboard and presentation prep; Author and/or review abstracts, presentations and manuscripts for accuracy of clinical data and content
• Provides support to Sr CDMD and/or GPCH in monitoring and safety data and signals the molecule for the assigned section of the clinical trial, may be a member of the Safety Management Team (SMT), and supports overall program safety reporting (e.g., Periodic Safety Update Reports (PSURs), Drug Safety Update Reports (DSURs), and other safety related documents) in collaboration with the medical monitor, CDMD and Patient Safety
• Ensures career development of Program reports and other clinical colleagues through active participation in the performance management and talent planning processes. Provides on-boarding, training, & mentoring support.
• Contributes to medical/scientific training of relevant stakeholders on the disease area and compound/molecule. May serve as speaker for franchise medical/scientific training
• May be assigned to lead clinical trial(s) as Clinical Scientific Lead and provide leadership and guidance for all clinical aspects of a clinical trial in close collaboration with the assigned medical monitor and/or CDMD.

Requirements

• PhD in Neuroscience (or similar)
• Experience in Neuroscience, Cell & Gene, Neurodegeneration, Rare or neuromuscular diseases, or Neuroinflammation (preferred).
• Preferred experience in Multiple Sclerosis, Huntington's Disease, Myasthenia Gravis, or similar conditions.
• Clinical Development Experience - Required - i.e. protocol and protocol documentation development
• Clinical Data Review Experience - ESSENTIAL: Oversees/conducts ongoing clinical and scientific review of clinical trial data with medical monitor, Clinical Scientific Expert(s) with appropriate oversight from Medical Lead. Work in close collaboration with the data management and statistics teams to ensure proper data quality and analysis of clinical trial results.
• At least 5 years or more in role of (or similar to) Clinical Development Director
• ≥ 7 years of involvement in clinical research or drug development in an academic or industry environment spanning clinical activities in Phases I through IV.
• ≥ 3 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry.

Interested candidates should submit an updated CV.

***Please note our client cannot assist with any visa sponsorship and candidates must have the correct visa to live and work in UK***

CPL Life Sciences are partnering with one of our long standing clients, a well-reputable global pharma, who are seeking a number of experienced Clinical Development Directors to provide strategic and scientific leadership across a range of their global clinical development programs in neurology, immunology, and cardiology . The role spans all phases of clinical research, from early to late phase.

• 18 month contract
• Fully remote
• £700 per day (Umbrella)

The successful individuals will oversee clinical strategy, protocol development, data interpretation, and contribute to regulatory interactions and documentation. The role requires cross-functional collaboration across data management, biostatistics, medical affairs, and regulatory functions. The successful candidate will also support inspection readiness, audit preparation, and stakeholder engagement (e.g., advisory boards, regulatory agencies, KOLs).

This is not a clinical operations position, and is instead responsible for the scientific input and clinical development progress of the current live studies. This will be in close collaboration with a wider development team.

Key Experience:

• Experience in one or more of; neurology, immunology, or cardiovascular indications
• Authoring and reviewing clinical trial protocols, investigator brochures, and study reports
• Oversight of medical monitoring and clinical data review activities
• Experience in contributing to global regulatory submissions and responses
• Strong background in safety data evaluation, risk management, and benefit-risk assessments
• Collaboration with cross-functional study teams and external stakeholders (e.g., CROs, regulatory bodies)
• Strategic input into clinical development plans and translational strategies
• Familiarity with inspection readiness, GCP audits, and regulatory compliance
• Development of publication strategies and review of scientific communications
• Ability to lead, mentor, and develop clinical team members within a matrix environment
• No line management required.
• Masters or PHD is preferable, but not essential

This is an excellent opportunity for an experienced clinical leader to make a significant impact within high-priority therapeutic areas and help shape the future of innovative treatments.

This is an exciting leadership role for a global pharmaceutical company with an international footprint in Neurology.

Our client is looking for a candidate who has experience in running and overseeing early stage clinical programs in the area of Neurology. You will be managing a team as well as project teams.

See the requirements below:

• Medical Doctor Degree, Neurology focus preferred.
• Experience in therapy area of Neurology (10+yrs)
• Experience running clinical programs - phase I-III
• Experience working in cross functional teams
• Experience managing high level projects
• Able to travel across Europe, (10-20%)