211 Clinical Monitoring jobs in the United Kingdom

Carrot Recruitment are acting as a recruitment agency on the sourcing of a Clinical Data Manager for a clinical-stage biotechnology company at the forefront of cancer drug development. Our client combines cutting-edge science with a patient-centric approach, offering a dynamic and mission-driven work environment. With recent strategic investments from major pharmaceutical partners, the company is well-funded and poised for significant growth.

This is a unique opportunity to contribute to the development of transformational therapies that aim to improve the lives of people with difficult-to-treat cancers who are classified as a top biotech to watch in this space

Everything you need to know about the role

As the Clinical Data Manager, you’ll have significant recent experience of managing all activities related to clinical data, and at all stages of process. You will be the responsible for all elements of the clinical data management and be able to showcase your ability to work in an agile and fast paced environment, with integrity and accuracy

• Serve as the lead Data Manager on a study level and contribute to the design of the eCRF, collection of data and review of data for accuracy and completeness
• Interact with members of the multidisciplinary project teams to provide ongoing data management support for clinical trials
• Familiarity with risk-based data management process
• Oversee database builds, including UAT, ensuring data integrity and security
• Participate in the development and implementation of the standard processes and guidelines for the DM function
• Management of data management tasks, on a study level performed by the vendor, in adherence with established standards including third party vendor data reconciliation, protocol deviation collection, SAE reconciliation and data issue resolution
• Coordinate internal cross functional review of data management documents, as required
• Stays abreast of new and/or evolving local regulations, guidelines and policies related to clinical development

Experience and qualities that make you a strong fit

• Bachelor’s degree in computer science, life sciences or equivalent
• Recent relevant experience in a Clinical Data role
• Current and up-to-date GCP training
• Experience in setting up EDC systems is essential, and vendor management experience preferred
• Experience in oncology essential, multiple myeloma preferred.
• In-depth understanding of clinical trial processes and involved functional stakeholders
• Knowledge of FDA, EMA and ICH regulations/guidelines and the drug development process is preferred but not essential
• Proficient in Excel

What’s on offer?

• A competitive salary
• Comprehensive benefits package, including medical insurance, pension, bonus and share scheme.
• Hybrid working model - 2 days per week on site (Manchester location preferred, although commuting distant Cambridge would also be possible)
• Opportunities to be part of a fast-growing biotech at a significant part of their development.

Could this be the role for you?

If you’re ready to take on this exciting opportunity and bring your expertise to a company that’s listed as one to watch, we’d love to hear from you. Please apply with your most recent CV, to be considered.

Overview

We are seeking an experienced Clinical Data Manager to join our Clinical Operations team. In this pivotal role, you will oversee and manage fully outsourced data management activities to ensure high-quality, timely, and compliant clinical data to support regulatory submissions and clinical development goals. This is a new role where you will take ownership of data oversight across all clinical studies. You will collaborate closely with CROs, vendors, internal cross-functional teams, and external stakeholders to ensure data integrity and operational excellence.

Key Responsibilities

• Serve as the primary data management contact for assigned clinical studies.
• Oversee CROs and vendors to ensure timely, high-quality delivery of all data management activities in compliance with GCP, ICH, and regulatory requirements.
• Review and approve essential data management documentation, including Data Management Plans (DMPs) and validation specifications.
• Ensure efficient execution of database go-live, interim reviews, and database lock processes.
• Monitor data quality and resolve issues proactively to maintain data integrity.
• Support regulatory submissions by ensuring availability of clean, compliant datasets.
• Stay current with industry standards and regulatory trends to drive continuous improvement in data management practices.

Must Haves

• Significant clinical data management experience, preferably in a biotech or pharmaceutical environment.
• Experience overseeing fully outsourced data management with CRO oversight.
• Strong understanding of GCP, ICH guidelines, and regulatory requirements for clinical data.
• Proficiency in EDC systems (e.g., Medidata Rave, Veeva EDC, Oracle Inform) and data review tools.

Why Join Us?

• Make a significant impact in an innovative and growing biotech company .
• Collaborative and innovative work environment.
• Competitive salary and benefits package.
• Remote working with regular team meetings.

Advanced analytics. Intelligent insights.

IXICO plc (AIM: IXI), is a leading neuroimaging Contract Research Organization (CRO), delivering advanced Ai analytical insights in neuroscience to the global clinical trials market. Established in 2004, listed as a public company in 2013, IXICO has firmly established itself as a trusted partner to the global life sciences industry, supporting the development of new therapies for neurological conditions such as Alzheimer’s, Parkinson’s, Huntington’s Disease and Multiple Sclerosis.

With our focus on neuroscience, our purpose is to advance human health by turning data into clinically valuable insights; helping our clients reduce clinical development risk and improve return on investment from their clinical development programmes. We achieve this by combining Ai machine learning imaging biomarker analysis, together with centralised neuroimaging CRO services to provide an integrated service covering every stage of clinical development through to post-marketing surveillance. We are committed to invest in continuously enhancing our validated and peer reviewed disease optimised machine learning Ai analytics services and our infrastructure and technology to support our ambitious growth strategy. Our people are empowered to enable us to achieve our company goals and their own personal development through the “4A” values at the heart of our culture: Aspiration, Ability, Agility and Accountability.

To help us deliver our medical image analysis solutions to large clinical trials we are hiring a Associate Data Manager on a permanent full-time capacity.

Purpose of the Role:

Working closely with the Project Manager and Science Lead, the Associate Clinical Data Manager will be responsible for data cleaning and transfer of clinical neuroimaging data on a varied portfolio of neurology clinical trials.

The Associate Clinical Data Manager will ensure the data management process on each new Project is setup, quality controlled, and managed robustly; meeting regularly with the Site Manager and Image Analyst to maintain oversight of this dataflow and support with issue resolutions, as and when they arise throughout the Project. The Associate Clinical Data Manager will be the escalation point and point of contact for the Sponsor and IXICO Project Manager on all data-related questions and is directly responsible for performing data checks/reconciliations, and execution of data and image transfers.

IXICO operates its own in-house Clinical Data Management (CDM) System called TrialTrackerTM along with cutting-edge Artificial Intelligence algorithms for analysing brain scans. IXICO’s processes are tailored for managing neuroimaging data and IXICO Clinical Data Managers have the opportunity to become specialised in handling neuroimaging data within a unique CDM system.

Essential Duties and Responsibilities:

The duties and responsibilities listed below are representative, but not exhaustive of the role. There may be some variation and/or development of these duties and responsibilities without changing the general nature of the role.

• Performs data management activities, focusing on data cleaning and data transfer of imaging data sent through to IXICO for assigned projects.
• Ensure the data cleaning and transfer processes on each new project is setup, quality controlled, and managed robustly.
• Attend and participate in sponsor meetings as requested.
• Act as the escalation point and point of contact for the Sponsor and IXICO project Manager on all data related questions.
• Perform QC on all aspects of work performed in Site Management, Image Analysis and Data Management teams to ensure that data quality and integrity is maintained.
• Run and perform routine ad hoc data cleaning checks on Project data, identifying errors, inconsistencies and discrepant data for resolution.
• Track outstanding issues and following-up until resolution.
• Maintain, organize, complete, and update study documentation, including writing Data Transfer Agreements and Image Transfer Agreements and configuring associated extracts for data transfer output.
• Write project-specific transfer work instructions and perform test/production transfers.
• Assist in standardising and documenting data management procedures.
• Follow all IXICO data management (DM) procedures, policies, and work instructions.
• Read, understand, and follow applicable Standard Operating Procedures (SOPs).

Qualifications and skills required for the role:

Essential

• Bachelor’s degree in Computer Science, Life Sciences or related field preferred, or equivalent experience required.
• 1+ years’ experience of working in data management within the Pharmaceutical, Biotech or CRO industry recommended.
• Strong IT skills (working within cloud-based database systems desirable) and demonstrate experience of working with a variety of data formats.
• Experience working with Microsoft Office tools including Word and in particular Excel.
• Ability to learn other computer systems, including databases.
• Strong attention to detail and excellent communication and interpersonal skills, both verbal and written.
• Team oriented and flexible; ability to function in high volume environment with competing priorities.
• Ability to perform multiple tasks simultaneously under direction and prioritise workload.
• Ability to work independently in a group setting; ability to adjust to changing priorities.
• Maintain a professional and positive attitude.

Desirable

• SAS Experience.
• SQL Experience.

Benefits

• Competitive remuneration package including benchmarked salaries.
• Staff Annual Bonus Plans and Annual Salary Review.
• Generous employer pension contribution of 6%.
• 25 days annual leave, increasing up to 28 days with every year at IXICO.
• BUPA private medical insurance scheme.
• Life Assurance of 4x annual salary.
• Employee Benefits Portal, Perkbox offering various discounts in retail, food & drink, and entertainment.
• Engaging and social environment, with fundraising and sporting activities and seasonal events such as Summer and Christmas parties.
• Wellbeing initiatives such as eye tests, flu jabs, and Mental Health Awareness Training.
• Employee Assistance Programme offering advice and support on a wide range of topics.
• Hybrid working model pattern split between working at our vibrant head office in the City of London and remotely.
• Reimbursement allowance to purchase equipment to support working from home.
• Generous employee referral scheme offering £2,000 for referring a successful candidate to the company.
• Financial assistance for professional qualifications.
• A company in an industry where your work has an impact every single day.

How to Apply

IXICO is working hard to create a representative, inclusive and empowered team, because we believe different experiences, perspectives and backgrounds make a better workplace, and ultimately better services.

IXICO doesn’t discriminate on the basis of race, colour, religion or belief, gender, national origin, age, sexual orientation, marital status, disability or any other protected class.

This is a great opportunity for a motivated Associate Data Manager in a permanent full-time capacity to thrive in an engaging and fast-paced environment, to make a difference on an everyday basis.

If you think IXICO should meet you, please send us your CV and covering letter by email to or apply directly via LinkedIn . We are looking forward to your application.

Please note that our entire business is operating under a Hybrid-Working Model , where UK-based employees are required to attend our London office 2 days a week . If you have got any questions, please reach out to our careers team.

Please note that IXICO will process the data provided by you only in order to perform the outlined recruitment exercise. For more details on what data we process and on what legal basis this happens please view our Recruitment Privacy Policy or contact

• Oversee the end-to-end clinical data management process for oncology studies.
• Design, build, and validate clinical databases (e.g., EDC systems) in accordance with study protocols and standards.
• Develop data management plans (DMPs) and data review guidelines.
• Execute data validation checks, identify data discrepancies, and generate/resolve data queries.
• Perform SAE reconciliation and ensure timely reporting of serious adverse events.
• Collaborate with clinical operations and medical teams to ensure data accuracy and completeness.
• Manage database lock processes and ensure data integrity for statistical analysis.
• Contribute to the development and maintenance of data management SOPs.
• Ensure compliance with ICH-GCP guidelines and other relevant regulatory requirements.
• Train and mentor junior data management staff as needed.

• Bachelor's degree in Life Sciences, Health Information Management, or a related field.
• Minimum of 5 years of experience as a Clinical Data Manager in pharmaceutical or CRO settings.
• Extensive experience with Electronic Data Capture (EDC) systems (e.g., Medidata Rave, Oracle Clinical).
• Strong understanding of CDISC standards (SDTM, ADaM) is essential.
• Experience managing oncology clinical trials is highly preferred.
• Proficiency in data analysis and reporting tools.
• Excellent understanding of ICH-GCP and other relevant regulatory guidelines.
• Exceptional attention to detail and organizational skills.
• Strong written and verbal communication skills for effective remote collaboration.
• Ability to work independently and manage multiple priorities in a remote setting.

• Develop and implement comprehensive Clinical Data Management Plans (CDMPs).
• Oversee the design, build, and validation of clinical databases using EDC systems.
• Develop data validation specifications and perform data review and cleaning activities.
• Manage query generation, resolution, and tracking to ensure data accuracy.
• Lead the process for database lock, ensuring all data is complete and validated.
• Ensure compliance with relevant regulatory guidelines (e.g., GCP, ICH, CDISC) and company SOPs.
• Liaise with clinical operations, biostatistics, and programming teams to ensure seamless data flow.
• Provide technical expertise and guidance to junior data managers and study team members.
• Contribute to the development and maintenance of data management tools and processes.
• Manage outsourced data management activities with CROs, as applicable.

An exciting opportunity to join Veramed's Data Management Business Unit! As we continue to grow and build on our success, we're looking to recruit a passionate and driven Senior Clinical Data Manager. You'll be required to have strong and indepth expereince of Data Management Study Start Up, Medidata Rave (including eCOA) and experience of vendor management. This role can be based in our UK offices or a hybrid working model.

Veramed prides itself on two key areas: providing the highest quality Data Management, Statistics and Programming consultancy for its clients, and giving its employees an industry leading working environment with support and training for career growth.

Purpose:

The role of the Senior Clinical Data Manager is to provide data management support to the data management department across a range of projects, sponsors and therapeutic areas. Provide expertise and manage the start up of new data management studies.

Key Responsibilities:

The job tasks listed below outline the scope of the position. The application of these tasks may vary, based on current business needs.

Technical:

• Review of clinical protocols
• Create or review Case Report Forms for data collection and compare with the protocol to ensure consistency
• Create or review Edit Check Specification document
• Preparation of UAT documentation and perform UAT of EDC and communication of findings
• Creation of study specific documents such as Data Management Plan, Data Review Plan, eCRF Completion Guidelines, etc.
• Create or review specifications for data review listings and / or customized reports to facilitate data cleaning
• Ongoing review of data entered in EDC to ensure the data is clean for analysis
• Issue queries to clinical monitors or investigational sites as appropriate
• Resolve standard queries
• Perform medical coding
• Work with external vendors on data transfer agreements / specifications
• Ensure external data is reconciled as required
• Track queries and data cleaning activities to ensure ongoing review of data entered is completed and data is fit for analysis.
• Maintain study master file documents and any other documents that are required to be audit ready
• Work in accordance with internal (or sponsor, where applicable) SOPs and procedures

Project Management:

• May serve as the main contact for the sponsor
• Awareness of study budget and proactive identification of scope changes
• Ensure key project milestones are delivered on time with the highest quality
• Maintain timelines and communicate risks / updates to the Data Management Project Manager
• Collaborate with cross-functional team members to ensure that the study deliverables are provided on time and with quality

General:

• Lead internal and client study team meetings effectively
• Present study updates internally and at sponsor meetings
• Share scientific, technical and practical knowledge within the team and with colleagues
• Perform work in full compliance with applicable legislation, regulations, company policies, procedures, and training
• Build effective collaborative working relationships with internal and sponsor team members
• Seek opportunities to develop innovative ideas and sharing when appropriate
• Mentorship of more junior team members
• Contribution to development of internal training materials
• Contribution to internal process improvement initiatives

Minimum Qualification Requirements

• BSc or MSc in numerical discipline (or relevant equivalent industry experience).
• At least 7 years of relevant industry experience.
• Understanding of clinical drug development process, relevant disease areas, endpoints, and different study designs
• Awareness of industry and project standards & ICH guidelines
• Excellent verbal and written communication skills
• Interpersonal/teamwork skills for effective interactions
• Self-management skills with a focus on results for timely and accurate completion of competing deliverables
• Demonstrated problem solving ability and attention to detail
• Project leadership experience
• Ability to make informed and appropriate decisions