47 Clinical Trial Manager jobs in London

We are seeking an experienced Clinical Trial Manager to join a London-based biotech and lead the planning, execution, and delivery of clinical trials. The successful candidate will excel in fast-paced, dynamic biotech settings and be committed to driving trials that meet the highest standards of quality, compliance, and operational excellence. Responsibilities: Lead the design, start-up, and execution of clinical trials, ensuring projects are completed on schedule, within scope, and aligned with budgetary expectations. Serve as the primary sponsor contact for CROs, investigators, and providers. Oversee CRO performance, including reviewing monitoring outputs and KPIs. Work closely with Regulatory Affairs on ethics/regulatory submissions, ensuring alignment with ICH-GCP guidelines and current UK/EU regulations. Maintain trial inspection readiness, overseeing safety reporting, audit response, and vendor governance. Develop and review protocols, informed consent forms, and study reports. Drive risk management, issue resolution, and collaboration across cross-functional teams. Play an active role in refining operational processes and SOPs within the Clinical Operations function. Requirements: Bachelor’s degree (or equivalent) in a life science or health-related discipline. Minimum of 8 years in clinical trial management across pharma, biotech, or CROs. Site monitoring experience or proven ability to critically evaluate CRO monitoring performance. In-depth understanding of ICH-GCP and global regulatory requirements, with strong understanding of upcoming UK/EU regulatory changes (e.g., UK CTR 2026). Demonstrated success in managing CROs and vendors, including financial oversight. Skilled at balancing multiple priorities and tight timelines. Proficient in navigating lean, fast-paced environments; direct experience in biotech settings is valued. Strong interpersonal and communication skills, with proven ability to manage internal stakeholders with accountability and transparency. Able to work on-site in central London in a hybrid capacity.

We are seeking an experienced Clinical Trial Manager to join a London-based biotech and lead the planning, execution, and delivery of clinical trials. The successful candidate will excel in fast-paced, dynamic biotech settings and be committed to driving trials that meet the highest standards of quality, compliance, and operational excellence.

Responsibilities:

• Lead the design, start-up, and execution of clinical trials, ensuring projects are completed on schedule, within scope, and aligned with budgetary expectations.
• Serve as the primary sponsor contact for CROs, investigators, and providers.
• Oversee CRO performance, including reviewing monitoring outputs and KPIs.
• Work closely with Regulatory Affairs on ethics/regulatory submissions, ensuring alignment with ICH-GCP guidelines and current UK/EU regulations.
• Maintain trial inspection readiness, overseeing safety reporting, audit response, and vendor governance.
• Develop and review protocols, informed consent forms, and study reports.
• Drive risk management, issue resolution, and collaboration across cross-functional teams.
• Play an active role in refining operational processes and SOPs within the Clinical Operations function.

Requirements:

• Bachelor’s degree (or equivalent) in a life science or health-related discipline.
• Minimum of 8 years in clinical trial management across pharma, biotech, or CROs.
• Site monitoring experience or proven ability to critically evaluate CRO monitoring performance.
• In-depth understanding of ICH-GCP and global regulatory requirements, with strong understanding of upcoming UK/EU regulatory changes (e.g., UK CTR 2026).
• Demonstrated success in managing CROs and vendors, including financial oversight.
• Skilled at balancing multiple priorities and tight timelines.
• Proficient in navigating lean, fast-paced environments; direct experience in biotech settings is valued.
• Strong interpersonal and communication skills, with proven ability to manage internal stakeholders with accountability and transparency.
• Able to work on-site in central London in a hybrid capacity.

Job Description

We are seeking an experienced Clinical Trial Manager to join a London-based biotech and lead the planning, execution, and delivery of clinical trials. The successful candidate will excel in fast-paced, dynamic biotech settings and be committed to driving trials that meet the highest standards of quality, compliance, and operational excellence.

Responsibilities:

• Lead the design, start-up, and execution of clinical trials, ensuring projects are completed on schedule, within scope, and aligned with budgetary expectations.
• Serve as the primary sponsor contact for CROs, investigators, and providers.
• Oversee CRO performance, including reviewing monitoring outputs and KPIs.
• Work closely with Regulatory Affairs on ethics/regulatory submissions, ensuring alignment with ICH-GCP guidelines and current UK/EU regulations.
• Maintain trial inspection readiness, overseeing safety reporting, audit response, and vendor governance.
• Develop and review protocols, informed consent forms, and study reports.
• Drive risk management, issue resolution, and collaboration across cross-functional teams.
• Play an active role in refining operational processes and SOPs within the Clinical Operations function.

Requirements:

• Bachelor’s degree (or equivalent) in a life science or health-related discipline.
• Minimum of 8 years in clinical trial management across pharma, biotech, or CROs.
• Site monitoring experience or proven ability to critically evaluate CRO monitoring performance.
• In-depth understanding of ICH-GCP and global regulatory requirements, with strong understanding of upcoming UK/EU regulatory changes (e.g., UK CTR 2026).
• Demonstrated success in managing CROs and vendors, including financial oversight.
• Skilled at balancing multiple priorities and tight timelines.
• Proficient in navigating lean, fast-paced environments; direct experience in biotech settings is valued.
• Strong interpersonal and communication skills, with proven ability to manage internal stakeholders with accountability and transparency.
• Able to work on-site in central London in a hybrid capacity.

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.
**Job Description**
**The Position**
Careers within the Clinical Operations team offers individuals the opportunity to develop their knowledge & experience rapidly whilst enjoying a supportive and team-focused working environment. Kite and Gilead's operational model allows each Clinical Operations professional to make a genuine impact on the business and ultimately our ability to deliver live changing therapeutics to those in need.
An exciting and challenging opportunity has arisen to join the European Headquarters based in Stockley Park, Uxbridge as a Clinical Trial Manager to be responsible for the management of European and/or global activities on assigned study(ies) within the Cell Therapy Area. **This role is Hybrid and requires 3 days per week at our Uxbridge offices**
**Essential Duties and Job Functions:**
+ Manages European component of global Phases II-III outsourced studies.
+ Drafts and coordinates review of relevant documents including protocols, informed consents, case report forms, monitoring plans, investigator brochures, and clinical study reports.
+ Maintains study timelines.
+ Contributes to development of study budget.
+ Contributes to development of RFPs and participate in selection of CROs/vendors.
+ Manages CROs/vendors.
+ Coordinates review of data listings and preparation of interim/final clinical study reports.
+ May contribute to development of abstracts, presentations, and manuscripts,
+ Ensures effectiveness of site budget/contract process.
+ May be asked to train CROs, vendors, investigators, and study coordinators on study requirements and cell therapy logistics.
+ Conducts oversight monitoring visits as required.
+ Assists in determining the activities to support a project's priorities within functional area.
+ Coordinates and supervises all aspects of a clinical study.
+ Under supervision, may design scientific communications within the company.
+ Contributes to Clinical Operations Europe team activities & initiatives
+ May serve as a resource for others within the company for clinical trials management expertise.
+ Under general supervision, is able to examine functional issues from an organizational perspective.
+ **Specific Responsibilities:**
+ Works with Clinical Program Managers and Global Clinical Trial Leads to manage the European component of global clinical trials and/or the entire process of a local clinical trial, with the ability to identify issues and adapt to changes. There might also be scope for global trial management.
+ Interacts with cross-functional teams internally and externally to ensure trial progress.
+ Will incorporate study logistics and planning to accomplish study objectives.
+ Will serve as the primary point of contact for CROs, addressing questions and applying knowledge to resolve problems
+ **Essential Functions:**
+ Oncology/Cell Therapy experience is highly preferable.
+ Must have multinational (preferably EU) clinical trials experience including study management/coordination.
+ Monitoring experience highly desirable as site oversight monitoring visits will be required.
+ Thorough knowledge and understanding of FDA and EU Regulations, ICH Guidelines, and GCPs governing the conduct of clinical trials is desirable.
+ Must be able to generally understand, interpret, and explain protocol requirements to others.
+ Must be able to prioritize multiple tasks.
+ Must be able to participate in multiple departmental or interdepartmental strategic initiatives under limited supervision.
+ Must have a general, functional expertise to support SOP development and implementation.
+ Must be able to resolve problems using national and international regulations, guidelines, and investigator interaction.
+ Excellent teamwork, communication, decision-making and organizational skills are required.
+ International travel is required (up to approximately 20%)
+ 3 days per week at Stockley Park
**_Gilead/Kite Core Values_**
INTEGRITY - Doing What's Right
INCLUSION - Encouraging Diversity
TEAMWORK - Working Together
EXCELLENCE - Being Your Best
ACCOUNTABILITY - Taking Personal Responsibility
**Equal Employment Opportunity (EEO)**
It is the policy of Gilead Sciences, Inc. and its subsidiaries and affiliates (collectively "Gilead" or the "Company") to recruit select and employ the most qualified persons available for positions throughout the Company. Except if otherwise provided by applicable law, all employment actions relating to issues such as compensation, benefits, transfers, layoffs, returns from layoffs, company-sponsored training, education assistance, social and recreational programs are administered on a non-discriminatory basis (i.e. without regard to protected characteristics or prohibited grounds, which may include an individual's gender, race, color, national origin, ancestry, religion, creed, physical or mental disability, marital status, sexual orientation, medical condition, veteran status, and age, unless such protection is prohibited by federal, state, municipal, provincial, local or other applicable laws). Gilead also prohibits discrimination based on any other characteristics protected by applicable laws.
**For Current Gilead Employees and Contractors:**
Please apply via the Internal Career Opportunities portal in Workday.
Gilead Sciences, Inc. is a biopharmaceutical company that has pursued and achieved breakthroughs in medicine for more than three decades, with the goal of creating a healthier world for all people. The company is committed to advancing innovative medicines to prevent and treat life-threatening diseases, including HIV, viral hepatitis and cancer. Gilead operates in more than 35 countries worldwide, with headquarters in Foster City, California.

Hobson Prior is seeking a Clinical Trial Supply Manager to join a dynamic team in Uxbridge, UK. In this role, you will play a key part in managing the supply chain for investigational products, ensuring timely delivery and alignment with clinical study goals. This position involves collaboration with internal teams and external partners to support global clinical trials in the cell and gene therapy/biologics space. Please note that to be considered for this role you must have the right to work in this location. Responsibilities: Develop and maintain supply strategies for investigational products based on clinical and regulatory requirements. Work closely with internal teams and external vendors to ensure all supply needs are met. Plan and communicate supply chain strategies to align with clinical study objectives. Monitor inventory, analyze drug usage, and adjust forecasts as needed. Oversee manufacturing, packaging, and labeling requests to meet protocol and regulatory standards. Support use date extensions and ensure compliance with country-specific regulations. Participate in meetings to provide updates, highlight risks, and propose mitigation strategies. Manage distribution strategies and maintain supply levels at depots and clinical sites. Collaborate on budget planning and procurement of commercial drugs. Act as the primary contact for clinical supply matters related to assigned studies. Ensure inspection readiness by preparing necessary documentation and addressing product complaints or deviations. Key Skills and Requirements: Strong understanding of global drug development processes and regulatory requirements. Proficient in forecasting, planning, and supply chain management. Knowledge of manufacturing, packaging, labeling, and logistics processes. Familiarity with industry systems such as IVRS and CTMS. Excellent communication, negotiation, and project management skills. Ability to analyze issues, resolve conflicts, and build consensus within teams. Experience in managing budgets and working with external vendors. For more information, please contact Emma Miles . If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists visit the 'Contact Us' page. Hobson Prior is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Hobson Prior is acting as an Employment Agency in relation to this vacancy. By submitting this application, you confirm that you've read and understood our privacy policy, which informs you how we process and safeguard your data -

Hobson Prior is seeking a Clinical Trial Supply Manager to join a dynamic team in Uxbridge, UK. In this role, you will play a key part in managing the supply chain for investigational products, ensuring timely delivery and alignment with clinical study goals. This position involves collaboration with internal teams and external partners to support global clinical trials in the cell and gene therapy/biologics space.

Please note that to be considered for this role you must have the right to work in this location.

Responsibilities:

• Develop and maintain supply strategies for investigational products based on clinical and regulatory requirements.
• Work closely with internal teams and external vendors to ensure all supply needs are met.
• Plan and communicate supply chain strategies to align with clinical study objectives.
• Monitor inventory, analyze drug usage, and adjust forecasts as needed.
• Oversee manufacturing, packaging, and labeling requests to meet protocol and regulatory standards.
• Support use date extensions and ensure compliance with country-specific regulations.
• Participate in meetings to provide updates, highlight risks, and propose mitigation strategies.
• Manage distribution strategies and maintain supply levels at depots and clinical sites.
• Collaborate on budget planning and procurement of commercial drugs.
• Act as the primary contact for clinical supply matters related to assigned studies.
• Ensure inspection readiness by preparing necessary documentation and addressing product complaints or deviations.

Key Skills and Requirements:

• Strong understanding of global drug development processes and regulatory requirements.
• Proficient in forecasting, planning, and supply chain management.
• Knowledge of manufacturing, packaging, labeling, and logistics processes.
• Familiarity with industry systems such as IVRS and CTMS.
• Excellent communication, negotiation, and project management skills.
• Ability to analyze issues, resolve conflicts, and build consensus within teams.
• Experience in managing budgets and working with external vendors.

For more information, please contact Emma Miles .

If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists visit the 'Contact Us' page.

Hobson Prior is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Hobson Prior is acting as an Employment Agency in relation to this vacancy.

By submitting this application, you confirm that you've read and understood our privacy policy, which informs you how we process and safeguard your data -

Job Description

Hobson Prior is seeking a Clinical Trial Supply Manager to join a dynamic team in Uxbridge, UK. In this role, you will play a key part in managing the supply chain for investigational products, ensuring timely delivery and alignment with clinical study goals. This position involves collaboration with internal teams and external partners to support global clinical trials in the cell and gene therapy/biologics space.

Please note that to be considered for this role you must have the right to work in this location.

Responsibilities:

• Develop and maintain supply strategies for investigational products based on clinical and regulatory requirements.
• Work closely with internal teams and external vendors to ensure all supply needs are met.
• Plan and communicate supply chain strategies to align with clinical study objectives.
• Monitor inventory, analyze drug usage, and adjust forecasts as needed.
• Oversee manufacturing, packaging, and labeling requests to meet protocol and regulatory standards.
• Support use date extensions and ensure compliance with country-specific regulations.
• Participate in meetings to provide updates, highlight risks, and propose mitigation strategies.
• Manage distribution strategies and maintain supply levels at depots and clinical sites.
• Collaborate on budget planning and procurement of commercial drugs.
• Act as the primary contact for clinical supply matters related to assigned studies.
• Ensure inspection readiness by preparing necessary documentation and addressing product complaints or deviations.

Key Skills and Requirements:

• Strong understanding of global drug development processes and regulatory requirements.
• Proficient in forecasting, planning, and supply chain management.
• Knowledge of manufacturing, packaging, labeling, and logistics processes.
• Familiarity with industry systems such as IVRS and CTMS.
• Excellent communication, negotiation, and project management skills.
• Ability to analyze issues, resolve conflicts, and build consensus within teams.
• Experience in managing budgets and working with external vendors.

For more information, please contact Emma Miles .

If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists visit the 'Contact Us' page.

Hobson Prior is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Hobson Prior is acting as an Employment Agency in relation to this vacancy.

By submitting this application, you confirm that you've read and understood our privacy policy, which informs you how we process and safeguard your data - -policy.

Our client, a rapidly expanding clinical research organization, is looking for an accomplished Director of Clinical Operations to lead their strategic initiatives on a fully remote basis. This senior leadership position offers a unique opportunity to drive operational excellence and shape the future of clinical trial management within a dynamic, global organization.

As the Director of Clinical Operations, you will be responsible for the overall planning, execution, and oversight of all clinical trial activities. You will lead a diverse team of clinical operations professionals, ensuring that trials are conducted on time, within budget, and in compliance with regulatory standards (GCP, FDA, EMA). Your role will involve developing and implementing strategic operational plans, optimizing resource allocation, and fostering strong relationships with investigative sites, vendors, and internal stakeholders. This position demands exceptional leadership, strategic thinking, and a deep understanding of the clinical research landscape.

Key responsibilities include:

• Developing and implementing comprehensive clinical operations strategies aligned with organizational goals.
• Overseeing the planning, execution, and monitoring of multiple clinical trials across various therapeutic areas.
• Leading, mentoring, and managing a high-performing team of clinical operations managers, CRAs, and study coordinators.
• Ensuring adherence to all relevant regulatory requirements, including Good Clinical Practice (GCP).
• Managing clinical trial budgets, timelines, and resource allocation effectively.
• Establishing and maintaining strong relationships with investigative sites, key opinion leaders, and vendors.
• Implementing and refining clinical operations processes and SOPs to enhance efficiency and quality.
• Driving continuous improvement initiatives within the clinical operations department.
• Managing vendor relationships and performance for critical study services.
• Reporting on clinical trial progress and operational performance to senior leadership and key stakeholders.

The ideal candidate will possess a Master's degree or PhD in a life science, healthcare, or related field, coupled with a minimum of 10-12 years of progressive experience in clinical operations management within the pharmaceutical or biotechnology industry. Proven experience in leading large-scale, complex clinical trials is essential. Demonstrated success in managing global clinical operations teams and budgets is required. Excellent strategic planning, problem-solving, and decision-making skills are critical. Strong understanding of regulatory requirements and a commitment to ethical research practices are paramount. This is a pivotal remote leadership role within a cutting-edge organization.