348 Drug jobs in the United Kingdom

Formulation Scientist - Drug Development

S1 4BS Sheffield, Yorkshire and the Humber £55000 Annually WhatJobs

Posted 2 days ago

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Job Description

full-time
Our client, a pioneering pharmaceutical company at the forefront of therapeutic innovation, is seeking a highly skilled Formulation Scientist to contribute to their drug development pipeline. This fully remote position allows you to leverage your expertise from anywhere, impacting the future of medicine. You will be instrumental in the design, development, and optimization of novel drug formulations for various therapeutic areas. This involves exploring and evaluating different dosage forms (e.g., oral solid dosage, injectables, topical) and excipients to achieve desired drug delivery profiles, stability, and bioavailability. You will conduct experimental studies, analyze data rigorously, and interpret results to guide formulation strategies. Collaboration with cross-functional teams, including analytical chemists, pharmacologists, and regulatory affairs specialists, is essential. The ideal candidate will possess a deep understanding of pharmaceutics, biopharmaceutics, and material science. Experience with formulation development techniques, characterization methods, and scale-up processes is crucial. You will be responsible for preparing comprehensive reports, technical documentation, and contributing to regulatory submissions. A commitment to scientific rigor, problem-solving, and staying current with industry advancements is key. This role offers a fantastic opportunity to work on cutting-edge projects and contribute to bringing life-changing therapies to patients worldwide. Your expertise in navigating the complexities of drug formulation and development will be highly valued in this remote role, allowing for flexible working arrangements.

Responsibilities:
  • Design and develop innovative drug formulations for various dosage forms, including oral solids, liquids, and injectables.
  • Evaluate and select appropriate excipients to achieve desired drug product performance (e.g., solubility, stability, bioavailability).
  • Conduct experimental studies to optimize formulation parameters and manufacturing processes.
  • Characterize drug product properties using various analytical techniques (e.g., DSC, TGA, XRPD, particle size analysis).
  • Develop and validate analytical methods for formulation analysis.
  • Troubleshoot formulation and process-related issues.
  • Prepare comprehensive reports, study protocols, and regulatory submission documents (e.g., IND, NDA).
  • Collaborate effectively with analytical, preclinical, and clinical development teams.
  • Stay abreast of current scientific literature, regulatory guidelines, and industry best practices in formulation science.
  • Contribute to intellectual property generation through patent filings.

Qualifications:
  • Ph.D. or Master's degree in Pharmaceutics, Pharmaceutical Sciences, Chemistry, or a related field.
  • Minimum of 5 years of hands-on experience in pharmaceutical formulation development.
  • Proven track record in developing various dosage forms and understanding drug delivery principles.
  • Strong knowledge of material science, excipients, and their impact on formulation performance.
  • Experience with formulation development techniques and analytical characterization methods.
  • Familiarity with regulatory guidelines (FDA, EMA) for drug product development.
  • Excellent scientific writing, data analysis, and problem-solving skills.
  • Ability to work independently and manage projects effectively in a remote environment.
  • Strong communication and collaboration skills for working with diverse teams.
  • Experience with lyophilization and sterile product development is a plus.
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Senior Formulation Scientist, Drug Development

LS1 1AA Leeds, Yorkshire and the Humber £60000 Annually WhatJobs

Posted 2 days ago

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full-time
Our client, a pioneering pharmaceutical company located in Leeds, West Yorkshire, UK , is seeking a highly skilled Senior Formulation Scientist to join their Drug Development team. This is a critical laboratory-based role focused on the development of innovative drug delivery systems. You will be responsible for designing, developing, and optimizing pharmaceutical formulations for various dosage forms, ensuring product efficacy, stability, and manufacturability. Key responsibilities include pre-formulation studies, excipient selection, formulation design, and process development. You will conduct physical and chemical characterization of raw materials and finished products, perform stability studies, and troubleshoot formulation challenges. The ideal candidate will possess a strong understanding of pharmaceutics, drug delivery technologies, and relevant regulatory guidelines (e.g., GMP). We are looking for individuals with excellent experimental skills, strong analytical abilities, and a proven track record in pharmaceutical formulation development. The ability to work independently, manage projects effectively, and collaborate with cross-functional teams including analytical development, quality control, and regulatory affairs is essential. This role requires a meticulous approach, a passion for scientific innovation, and a commitment to bringing life-changing medicines to patients. You will be instrumental in advancing pipeline projects from early development through to clinical trials and potential commercialization. The ability to mentor junior scientists and contribute to scientific strategy is also highly valued.

Key Responsibilities:
  • Design and develop pharmaceutical formulations for various dosage forms.
  • Conduct pre-formulation studies and excipient compatibility testing.
  • Optimize formulation parameters and manufacturing processes.
  • Perform physical and chemical characterization of drug products.
  • Conduct and interpret stability studies according to ICH guidelines.
  • Troubleshoot formulation and manufacturing issues.
  • Collaborate with analytical development and quality control teams.
  • Prepare technical reports, development summaries, and regulatory documentation.
  • Stay current with advancements in drug delivery technologies and formulation science.
  • Mentor and guide junior formulation scientists.

Qualifications:
  • MSc or PhD in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related field.
  • Minimum of 5 years of experience in pharmaceutical formulation development.
  • Strong knowledge of drug delivery systems and dosage form design.
  • Proficiency in formulation characterization techniques and analytical methods.
  • Understanding of GMP principles and regulatory requirements.
  • Excellent problem-solving and critical thinking skills.
  • Effective communication and collaboration abilities.
  • Experience with solid dosage forms (e.g., tablets, capsules) is highly preferred.
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Senior Formulation Scientist - Drug Development

RG1 1DQ Reading, South East £75000 Annually WhatJobs

Posted 5 days ago

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full-time
Our client, a leading pharmaceutical innovator, is seeking a highly skilled Senior Formulation Scientist to join their Research & Development team in Reading, Berkshire, UK . This critical role will focus on the design, development, and optimization of novel drug delivery systems and dosage forms for a range of therapeutic areas. You will be instrumental in advancing drug candidates from early-stage development through to clinical trials and regulatory submission. Responsibilities include conducting pre-formulation studies, developing solid, semi-solid, and liquid dosage forms, and performing comprehensive characterization and stability testing. The ideal candidate will possess a strong scientific background in pharmaceutical sciences, ideally with a PhD or Master's degree, and extensive experience in formulation development for oral, parenteral, or topical delivery. You will be proficient in a variety of formulation techniques and analytical methods, including HPLC, DSC, TGA, and dissolution testing. Experience with advanced drug delivery technologies, such as nanoparticles, liposomes, or controlled-release systems, is highly desirable. This role demands excellent problem-solving abilities, a deep understanding of drug product quality attributes, and regulatory guidelines (e.g., ICH). You will collaborate closely with analytical development, DMPK, process development, and regulatory affairs teams to ensure seamless project progression. The ability to critically evaluate experimental data, design robust experimental plans, and contribute to scientific publications and patent applications will be key. You will also be expected to stay current with scientific literature and industry best practices to drive innovation in formulation science.

Key Responsibilities:
  • Design and develop innovative drug formulations and dosage forms.
  • Conduct pre-formulation studies and physicochemical characterization.
  • Optimize formulation parameters to achieve desired drug product performance.
  • Perform stability studies and analyze results to ensure product quality.
  • Collaborate with analytical and process development teams.
  • Troubleshoot formulation challenges and propose effective solutions.
  • Contribute to the preparation of regulatory documentation.
  • Stay updated on new technologies and scientific advancements in drug formulation.
  • Mentor junior scientists and contribute to team knowledge sharing.

Qualifications:
  • PhD or Master's degree in Pharmaceutical Sciences, Pharmaceutics, or a related discipline.
  • Minimum of 7 years of experience in pharmaceutical formulation development.
  • Proven expertise in developing various dosage forms (e.g., oral, parenteral).
  • Proficiency in formulation techniques and analytical characterization methods.
  • Knowledge of regulatory requirements and guidelines (ICH).
  • Strong problem-solving and critical thinking skills.
  • Excellent written and verbal communication abilities.
  • Experience with advanced drug delivery systems is a plus.
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Principal Scientist - Drug Discovery & Development

CF10 1EP Cardiff, Wales £70000 Annually WhatJobs

Posted 5 days ago

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full-time
Our client, a cutting-edge pharmaceutical company at the forefront of innovative drug development, is seeking a highly experienced Principal Scientist to join their esteemed research and development team in Cardiff, Wales, UK . This is a key role for an individual with a proven track record in preclinical drug discovery, medicinal chemistry, or a related field, who is passionate about bringing life-changing therapies to patients.

As a Principal Scientist, you will lead critical research projects, driving the discovery and optimization of novel therapeutic candidates from target validation through to candidate selection. You will design and execute complex experiments, interpret scientific data, and contribute significantly to the intellectual property strategy of the company. The ideal candidate will possess exceptional scientific rigor, a deep understanding of molecular biology, pharmacology, and chemistry, and strong leadership capabilities. You will be expected to mentor junior scientists, collaborate effectively with internal and external partners, and present findings at international conferences.

Key Responsibilities:
  • Lead and manage multiple drug discovery projects, ensuring scientific excellence and timely delivery.
  • Design and implement innovative experimental strategies to identify and validate novel drug targets and lead compounds.
  • Conduct advanced biochemical, cellular, and pharmacological assays to characterize compound activity and selectivity.
  • Develop and optimize synthetic routes for medicinal chemistry programs.
  • Analyze complex biological and chemical data, drawing robust conclusions and making data-driven decisions.
  • Prepare comprehensive study reports, manuscripts for publication, and regulatory filings.
  • Present research findings clearly and effectively to internal teams, senior management, and external collaborators.
  • Mentor and train junior scientists and research associates, fostering a collaborative and high-performing team environment.
  • Collaborate closely with cross-functional teams including DMPK, toxicology, and clinical development.
  • Contribute to the strategic planning of the R&D pipeline and identify new therapeutic opportunities.
  • Maintain a deep understanding of the latest scientific literature and technological advancements in the field.

Qualifications:
  • Ph.D. in Pharmacology, Medicinal Chemistry, Biochemistry, Molecular Biology, or a closely related discipline.
  • A minimum of 8 years of post-doctoral research experience in the pharmaceutical or biotechnology industry, with a focus on small molecule drug discovery.
  • Demonstrated success in leading preclinical drug discovery projects from initiation to candidate selection.
  • Expertise in a specific therapeutic area (e.g., oncology, neuroscience, infectious diseases) is highly desirable.
  • Proficiency in modern drug discovery techniques, including high-throughput screening, structure-based drug design, and lead optimization strategies.
  • Strong understanding of pharmacokinetics, pharmacodynamics, and drug metabolism.
  • Excellent leadership, project management, and communication skills.
  • Ability to work effectively in a fast-paced, matrixed organization.
  • Strong publication record in peer-reviewed journals and presentations at scientific meetings.

This role offers a competitive salary, excellent benefits, and the opportunity to make a tangible impact on patient lives within a dynamic and supportive scientific environment.
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Principal Scientist, Drug Discovery & Development

NR1 1NA Norwich, Eastern £80000 Annually WhatJobs

Posted 5 days ago

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full-time
Our client, a rapidly growing pharmaceutical company, is seeking a highly accomplished Principal Scientist to lead critical initiatives in drug discovery and development within their Norwich, Norfolk, UK research facility. This senior role involves spearheading research programmes, designing experimental strategies, and advancing novel therapeutic candidates through the preclinical pipeline. You will be responsible for the scientific integrity and success of assigned projects, from target identification and validation through to early-stage drug development. Your expertise will be crucial in planning and executing complex experiments, analysing data, and interpreting results to guide decision-making.

The ideal candidate will possess a PhD in Pharmacology, Biochemistry, Molecular Biology, or a related life science discipline, complemented by substantial post-doctoral and industry experience in drug discovery. A deep understanding of relevant therapeutic areas, assay development, and preclinical models is essential. Proven experience in managing research projects, leading small teams, and mentoring junior scientists is a requirement. You should have a strong track record of scientific achievement, demonstrated through publications, patents, and successful progression of drug candidates. Excellent critical thinking, problem-solving, and communication skills are paramount for collaborating with multidisciplinary teams, including chemists, biologists, toxicologists, and clinical scientists. Experience with data analysis software and statistical methods is crucial. This role offers the opportunity to make a significant impact on the development of life-saving medicines and to contribute to cutting-edge scientific advancements in the pharmaceutical industry.

Key responsibilities:
  • Lead and manage drug discovery research projects.
  • Design and execute complex experimental strategies.
  • Identify and validate novel therapeutic targets.
  • Develop and optimise assays for compound screening and characterisation.
  • Analyse and interpret experimental data, ensuring scientific rigour.
  • Guide preclinical development of drug candidates.
  • Collaborate with cross-functional research and development teams.
  • Mentor and supervise junior scientific staff.
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Senior Formulation Scientist - Drug Product Development

WC1A 0AA London, London £70000 Annually WhatJobs

Posted 1 day ago

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full-time
Our client, a globally recognized pharmaceutical company at the forefront of therapeutic innovation, is seeking a highly accomplished Senior Formulation Scientist to join their distinguished Drug Product Development team. This role, located at our premier research and development centre in London, England, UK , will operate on a hybrid basis. You will be responsible for the design, development, and optimization of novel drug formulations that ensure drug efficacy, stability, and patient compliance. This position demands a meticulous scientist with extensive knowledge of pharmaceutical sciences, formulation technologies, and regulatory requirements.

Key Responsibilities:
  • Lead the development of innovative drug delivery systems and formulations for various dosage forms (e.g., oral, injectable, topical).
  • Conduct pre-formulation studies to characterise active pharmaceutical ingredients (APIs) and excipients.
  • Design and execute experiments to develop stable and bioavailable drug products.
  • Utilise various formulation technologies, including solid dispersions, nanotechnology, and controlled-release systems.
  • Perform comprehensive stability studies according to ICH guidelines.
  • Characterise formulated drug products using advanced analytical techniques (e.g., HPLC, dissolution testing, particle size analysis).
  • Collaborate closely with analytical development, manufacturing, and regulatory affairs teams.
  • Prepare scientific reports, technical documentation, and regulatory submission documents.
  • Stay abreast of the latest advancements in pharmaceutical formulation and drug delivery.
  • Mentor junior scientists and contribute to the scientific growth of the team.

Qualifications:
  • PhD in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related discipline.
  • Minimum of 5-7 years of industry experience in pharmaceutical formulation development.
  • Demonstrated expertise in developing various dosage forms and drug delivery systems.
  • In-depth understanding of API characterization, excipient compatibility, and formulation stability.
  • Proficiency with pharmaceutical analytical techniques and instrumentation.
  • Strong knowledge of regulatory guidelines (e.g., FDA, EMA) pertaining to drug product development.
  • Excellent scientific thinking, problem-solving, and experimental design skills.
  • Effective communication and interpersonal skills, with the ability to work collaboratively in a multidisciplinary team.
  • Experience working in a hybrid environment.
This is an exceptional opportunity for a seasoned formulation scientist to contribute to the development of life-changing medicines and advance their career within a prestigious organisation. The successful candidate will receive a competitive remuneration package and the chance to work at the cutting edge of pharmaceutical innovation.
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Senior Pharmaceutical Scientist - Drug Discovery & Development

CB2 1TN Cambridge, Eastern £75000 Annually WhatJobs

Posted 5 days ago

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Job Description

full-time
Our client, a leading pharmaceutical company, is looking for a highly skilled Senior Pharmaceutical Scientist to join their R&D team in **Cambridge, Cambridgeshire, UK**. This pivotal role will involve contributing to the drug discovery and development process, focusing on formulation science, pre-clinical studies, and regulatory submission support. The ideal candidate will possess a PhD or MSc in Pharmaceutical Sciences, Chemistry, or a related discipline, with extensive experience in pharmaceutical R&D.

Key Responsibilities:
  • Lead and execute research projects focused on novel drug delivery systems and formulation development.
  • Design and conduct experiments to evaluate drug product performance, stability, and bioavailability.
  • Develop and validate analytical methods for drug substance and drug product characterisation.
  • Prepare comprehensive technical reports, research summaries, and regulatory documentation (e.g., CMC sections).
  • Collaborate closely with cross-functional teams including medicinal chemistry, pharmacology, and clinical development.
  • Mentor junior scientists and provide technical guidance on research activities.
  • Stay abreast of scientific literature, regulatory guidelines, and industry trends in pharmaceutical development.
  • Troubleshoot formulation and analytical challenges, proposing innovative solutions.
  • Contribute to intellectual property generation through invention disclosures.
  • Represent the company at scientific conferences and external meetings.
  • Ensure all laboratory activities comply with Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) standards.
  • Assist in the scale-up of manufacturing processes from laboratory to pilot and commercial scale.
This is an exceptional opportunity to work at the forefront of pharmaceutical innovation in a highly collaborative and scientifically rigorous environment. We are seeking a motivated individual with strong scientific acumen, excellent problem-solving skills, and a proven ability to manage complex projects. The successful candidate will demonstrate leadership potential and a commitment to advancing patient health through cutting-edge pharmaceutical science. Experience with specific therapeutic areas or drug delivery technologies is highly desirable.
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Scientist - Injectable Drug Product Process Development

Hobson Prior

Posted today

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Help bring science to life and join a leading pharmaceutical company to play a key role in delivering impactful medicines that drives healthcare innovation!

Hobson Prior is seeking a Drug Product Development Specialist to join a dynamic team within Pharmaceutical Development Sciences. This role focuses on injectable drug product manufacturing processes, supporting clinical and regulatory activities. You will collaborate with internal teams and external partners to ensure the successful development and production of sterile drug products.

Please note that to be considered for this role you must have the right to work in this location.

Responsibilities:

  • Develop and refine manufacturing processes for injectable drug products from early studies to regulatory approval.
  • Select and define manufacturing parameters for clinical production.
  • Collaborate with internal teams and external manufacturers to meet project goals.
  • Conduct lab studies, analyse data, and document findings (e.g., filter selection, fill volume assessments, compatibility tests).
  • Analyse manufacturing data to improve process understanding and performance.
  • Perform risk assessments for manufacturing processes.
  • Design processes for sterile injectable products in various forms (e.g., liquid, lyophilized powder, pre-filled syringes).
  • Support clinical trial preparation and ensure timely production of stability and clinical batches.
  • Assist in process validation and ensure compliance with quality standards and regulations.
  • Contribute to regulatory submissions and respond to authority queries.
  • Investigate and resolve quality-related issues, such as deviations or complaints.
  • Facilitate knowledge transfer from late-phase development to commercial production.
  • Help improve departmental processes and ways of working.

Key Skills and Requirements:

  • Experience in developing or manufacturing liquid drug products in the pharmaceutical industry.
  • Familiarity with biopharmaceuticals is a plus.
  • Knowledge of aseptic manufacturing processes, including vial, cartridge, and pre-filled syringe filling, is advantageous.
  • Understanding of sterile drug product development, including components, process transfer, scale-up, and optimization, is beneficial.

For more information, please contact Jessica Taylor.

If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists visit the 'Contact Us' page.

Hobson Prior is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Hobson Prior is acting as an Employment Agency in relation to this vacancy.

By submitting this application, you confirm that you've read and understood our privacy policy, which informs you how we process and safeguard your data -

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Drug Safety Administrator

MK1 Milton Keynes, South East Aspire Personnel Ltd

Posted 6 days ago

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Job Description

full time

Our client is a market leader within the Pharma Covigilance market. They are looking to recruit a Drug Safety Administrator who will be an active participant in meetings and assist the PV Manager in maintaining standard operating procedures or working practices. During their daily activities, the Drug Safety Administrator will be required to liaise with pharmaceutical companies and other business partners.

Daily tasks:

  • Keeping the Pharmacovigilance Manager fully informed of problems and issues that may arise related to the product, adverse events, the patients, prescribers or the marketing authorisation holder.
  • Processing selected case reports in the database.
  • Checking all literature case reports have the appropriate AE terms assigned for MedDRA coding. Notifying the QPPV of cases where the appropriate MedDRA term cannot be identified independently.
  • Reconciliation both with clients and/or with PV partners on behalf of clients (as required).
  • Processing reports from any source in the drug safety database.
  • Assessing adverse events and carry out listedness and causality assessments.
  • Exchanging a PV case reference from the database with PV partners.
  • Conducting follow-up investigation for direct reports from either patients or healthcare professionals.
  • Maintaining Continued Professional Development in support of your role and responsibilities.
  • Participate in various team meetings and liaise with other colleagues about on-going projects.
  • Assist with documentation such as Working Practices and Standard Operating Procedures, where required.
  • Develop a thorough knowledge of medicinal products and with regulations and guidelines within the industry.
  • An organised, proactive person with excellent attention to detail.
  • Excellent oral and written communication with proficiency in standard software programs.

Minimum Requirements:

  • Life science or Bio medical graduate (1-2 years working experience desirable) or other allied healthcare professional.

Please note candidates will only be considered with the above skills and unfortunately this company cannot consider sponsorship, or a visa status that will need renewing.

This advertiser has chosen not to accept applicants from your region.

Drug Safety Administrator

Buckinghamshire, South East £26000 - £27000 Annually Aspire Personnel Ltd

Posted 6 days ago

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Job Description

permanent

Our client is a market leader within the Pharma Covigilance market. They are looking to recruit a Drug Safety Administrator who will be an active participant in meetings and assist the PV Manager in maintaining standard operating procedures or working practices. During their daily activities, the Drug Safety Administrator will be required to liaise with pharmaceutical companies and other business partners.

Daily tasks:

  • Keeping the Pharmacovigilance Manager fully informed of problems and issues that may arise related to the product, adverse events, the patients, prescribers or the marketing authorisation holder.
  • Processing selected case reports in the database.
  • Checking all literature case reports have the appropriate AE terms assigned for MedDRA coding. Notifying the QPPV of cases where the appropriate MedDRA term cannot be identified independently.
  • Reconciliation both with clients and/or with PV partners on behalf of clients (as required).
  • Processing reports from any source in the drug safety database.
  • Assessing adverse events and carry out listedness and causality assessments.
  • Exchanging a PV case reference from the database with PV partners.
  • Conducting follow-up investigation for direct reports from either patients or healthcare professionals.
  • Maintaining Continued Professional Development in support of your role and responsibilities.
  • Participate in various team meetings and liaise with other colleagues about on-going projects.
  • Assist with documentation such as Working Practices and Standard Operating Procedures, where required.
  • Develop a thorough knowledge of medicinal products and with regulations and guidelines within the industry.
  • An organised, proactive person with excellent attention to detail.
  • Excellent oral and written communication with proficiency in standard software programs.

Minimum Requirements:

  • Life science or Bio medical graduate (1-2 years working experience desirable) or other allied healthcare professional.

Please note candidates will only be considered with the above skills and unfortunately this company cannot consider sponsorship, or a visa status that will need renewing.

This advertiser has chosen not to accept applicants from your region.
 

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