348 Drug jobs in the United Kingdom
Formulation Scientist - Drug Development
Posted 2 days ago
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Job Description
Responsibilities:
- Design and develop innovative drug formulations for various dosage forms, including oral solids, liquids, and injectables.
- Evaluate and select appropriate excipients to achieve desired drug product performance (e.g., solubility, stability, bioavailability).
- Conduct experimental studies to optimize formulation parameters and manufacturing processes.
- Characterize drug product properties using various analytical techniques (e.g., DSC, TGA, XRPD, particle size analysis).
- Develop and validate analytical methods for formulation analysis.
- Troubleshoot formulation and process-related issues.
- Prepare comprehensive reports, study protocols, and regulatory submission documents (e.g., IND, NDA).
- Collaborate effectively with analytical, preclinical, and clinical development teams.
- Stay abreast of current scientific literature, regulatory guidelines, and industry best practices in formulation science.
- Contribute to intellectual property generation through patent filings.
Qualifications:
- Ph.D. or Master's degree in Pharmaceutics, Pharmaceutical Sciences, Chemistry, or a related field.
- Minimum of 5 years of hands-on experience in pharmaceutical formulation development.
- Proven track record in developing various dosage forms and understanding drug delivery principles.
- Strong knowledge of material science, excipients, and their impact on formulation performance.
- Experience with formulation development techniques and analytical characterization methods.
- Familiarity with regulatory guidelines (FDA, EMA) for drug product development.
- Excellent scientific writing, data analysis, and problem-solving skills.
- Ability to work independently and manage projects effectively in a remote environment.
- Strong communication and collaboration skills for working with diverse teams.
- Experience with lyophilization and sterile product development is a plus.
Senior Formulation Scientist, Drug Development
Posted 2 days ago
Job Viewed
Job Description
Key Responsibilities:
- Design and develop pharmaceutical formulations for various dosage forms.
- Conduct pre-formulation studies and excipient compatibility testing.
- Optimize formulation parameters and manufacturing processes.
- Perform physical and chemical characterization of drug products.
- Conduct and interpret stability studies according to ICH guidelines.
- Troubleshoot formulation and manufacturing issues.
- Collaborate with analytical development and quality control teams.
- Prepare technical reports, development summaries, and regulatory documentation.
- Stay current with advancements in drug delivery technologies and formulation science.
- Mentor and guide junior formulation scientists.
Qualifications:
- MSc or PhD in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related field.
- Minimum of 5 years of experience in pharmaceutical formulation development.
- Strong knowledge of drug delivery systems and dosage form design.
- Proficiency in formulation characterization techniques and analytical methods.
- Understanding of GMP principles and regulatory requirements.
- Excellent problem-solving and critical thinking skills.
- Effective communication and collaboration abilities.
- Experience with solid dosage forms (e.g., tablets, capsules) is highly preferred.
Senior Formulation Scientist - Drug Development
Posted 5 days ago
Job Viewed
Job Description
Key Responsibilities:
- Design and develop innovative drug formulations and dosage forms.
- Conduct pre-formulation studies and physicochemical characterization.
- Optimize formulation parameters to achieve desired drug product performance.
- Perform stability studies and analyze results to ensure product quality.
- Collaborate with analytical and process development teams.
- Troubleshoot formulation challenges and propose effective solutions.
- Contribute to the preparation of regulatory documentation.
- Stay updated on new technologies and scientific advancements in drug formulation.
- Mentor junior scientists and contribute to team knowledge sharing.
Qualifications:
- PhD or Master's degree in Pharmaceutical Sciences, Pharmaceutics, or a related discipline.
- Minimum of 7 years of experience in pharmaceutical formulation development.
- Proven expertise in developing various dosage forms (e.g., oral, parenteral).
- Proficiency in formulation techniques and analytical characterization methods.
- Knowledge of regulatory requirements and guidelines (ICH).
- Strong problem-solving and critical thinking skills.
- Excellent written and verbal communication abilities.
- Experience with advanced drug delivery systems is a plus.
Principal Scientist - Drug Discovery & Development
Posted 5 days ago
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Job Description
As a Principal Scientist, you will lead critical research projects, driving the discovery and optimization of novel therapeutic candidates from target validation through to candidate selection. You will design and execute complex experiments, interpret scientific data, and contribute significantly to the intellectual property strategy of the company. The ideal candidate will possess exceptional scientific rigor, a deep understanding of molecular biology, pharmacology, and chemistry, and strong leadership capabilities. You will be expected to mentor junior scientists, collaborate effectively with internal and external partners, and present findings at international conferences.
Key Responsibilities:
- Lead and manage multiple drug discovery projects, ensuring scientific excellence and timely delivery.
- Design and implement innovative experimental strategies to identify and validate novel drug targets and lead compounds.
- Conduct advanced biochemical, cellular, and pharmacological assays to characterize compound activity and selectivity.
- Develop and optimize synthetic routes for medicinal chemistry programs.
- Analyze complex biological and chemical data, drawing robust conclusions and making data-driven decisions.
- Prepare comprehensive study reports, manuscripts for publication, and regulatory filings.
- Present research findings clearly and effectively to internal teams, senior management, and external collaborators.
- Mentor and train junior scientists and research associates, fostering a collaborative and high-performing team environment.
- Collaborate closely with cross-functional teams including DMPK, toxicology, and clinical development.
- Contribute to the strategic planning of the R&D pipeline and identify new therapeutic opportunities.
- Maintain a deep understanding of the latest scientific literature and technological advancements in the field.
Qualifications:
- Ph.D. in Pharmacology, Medicinal Chemistry, Biochemistry, Molecular Biology, or a closely related discipline.
- A minimum of 8 years of post-doctoral research experience in the pharmaceutical or biotechnology industry, with a focus on small molecule drug discovery.
- Demonstrated success in leading preclinical drug discovery projects from initiation to candidate selection.
- Expertise in a specific therapeutic area (e.g., oncology, neuroscience, infectious diseases) is highly desirable.
- Proficiency in modern drug discovery techniques, including high-throughput screening, structure-based drug design, and lead optimization strategies.
- Strong understanding of pharmacokinetics, pharmacodynamics, and drug metabolism.
- Excellent leadership, project management, and communication skills.
- Ability to work effectively in a fast-paced, matrixed organization.
- Strong publication record in peer-reviewed journals and presentations at scientific meetings.
This role offers a competitive salary, excellent benefits, and the opportunity to make a tangible impact on patient lives within a dynamic and supportive scientific environment.
Principal Scientist, Drug Discovery & Development
Posted 5 days ago
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Job Description
The ideal candidate will possess a PhD in Pharmacology, Biochemistry, Molecular Biology, or a related life science discipline, complemented by substantial post-doctoral and industry experience in drug discovery. A deep understanding of relevant therapeutic areas, assay development, and preclinical models is essential. Proven experience in managing research projects, leading small teams, and mentoring junior scientists is a requirement. You should have a strong track record of scientific achievement, demonstrated through publications, patents, and successful progression of drug candidates. Excellent critical thinking, problem-solving, and communication skills are paramount for collaborating with multidisciplinary teams, including chemists, biologists, toxicologists, and clinical scientists. Experience with data analysis software and statistical methods is crucial. This role offers the opportunity to make a significant impact on the development of life-saving medicines and to contribute to cutting-edge scientific advancements in the pharmaceutical industry.
Key responsibilities:
- Lead and manage drug discovery research projects.
- Design and execute complex experimental strategies.
- Identify and validate novel therapeutic targets.
- Develop and optimise assays for compound screening and characterisation.
- Analyse and interpret experimental data, ensuring scientific rigour.
- Guide preclinical development of drug candidates.
- Collaborate with cross-functional research and development teams.
- Mentor and supervise junior scientific staff.
Senior Formulation Scientist - Drug Product Development
Posted 1 day ago
Job Viewed
Job Description
Key Responsibilities:
- Lead the development of innovative drug delivery systems and formulations for various dosage forms (e.g., oral, injectable, topical).
- Conduct pre-formulation studies to characterise active pharmaceutical ingredients (APIs) and excipients.
- Design and execute experiments to develop stable and bioavailable drug products.
- Utilise various formulation technologies, including solid dispersions, nanotechnology, and controlled-release systems.
- Perform comprehensive stability studies according to ICH guidelines.
- Characterise formulated drug products using advanced analytical techniques (e.g., HPLC, dissolution testing, particle size analysis).
- Collaborate closely with analytical development, manufacturing, and regulatory affairs teams.
- Prepare scientific reports, technical documentation, and regulatory submission documents.
- Stay abreast of the latest advancements in pharmaceutical formulation and drug delivery.
- Mentor junior scientists and contribute to the scientific growth of the team.
Qualifications:
- PhD in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related discipline.
- Minimum of 5-7 years of industry experience in pharmaceutical formulation development.
- Demonstrated expertise in developing various dosage forms and drug delivery systems.
- In-depth understanding of API characterization, excipient compatibility, and formulation stability.
- Proficiency with pharmaceutical analytical techniques and instrumentation.
- Strong knowledge of regulatory guidelines (e.g., FDA, EMA) pertaining to drug product development.
- Excellent scientific thinking, problem-solving, and experimental design skills.
- Effective communication and interpersonal skills, with the ability to work collaboratively in a multidisciplinary team.
- Experience working in a hybrid environment.
Senior Pharmaceutical Scientist - Drug Discovery & Development
Posted 5 days ago
Job Viewed
Job Description
Key Responsibilities:
- Lead and execute research projects focused on novel drug delivery systems and formulation development.
- Design and conduct experiments to evaluate drug product performance, stability, and bioavailability.
- Develop and validate analytical methods for drug substance and drug product characterisation.
- Prepare comprehensive technical reports, research summaries, and regulatory documentation (e.g., CMC sections).
- Collaborate closely with cross-functional teams including medicinal chemistry, pharmacology, and clinical development.
- Mentor junior scientists and provide technical guidance on research activities.
- Stay abreast of scientific literature, regulatory guidelines, and industry trends in pharmaceutical development.
- Troubleshoot formulation and analytical challenges, proposing innovative solutions.
- Contribute to intellectual property generation through invention disclosures.
- Represent the company at scientific conferences and external meetings.
- Ensure all laboratory activities comply with Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) standards.
- Assist in the scale-up of manufacturing processes from laboratory to pilot and commercial scale.
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Scientist - Injectable Drug Product Process Development
Posted today
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Job Description
Help bring science to life and join a leading pharmaceutical company to play a key role in delivering impactful medicines that drives healthcare innovation!
Hobson Prior is seeking a Drug Product Development Specialist to join a dynamic team within Pharmaceutical Development Sciences. This role focuses on injectable drug product manufacturing processes, supporting clinical and regulatory activities. You will collaborate with internal teams and external partners to ensure the successful development and production of sterile drug products.
Please note that to be considered for this role you must have the right to work in this location.
Responsibilities:
- Develop and refine manufacturing processes for injectable drug products from early studies to regulatory approval.
- Select and define manufacturing parameters for clinical production.
- Collaborate with internal teams and external manufacturers to meet project goals.
- Conduct lab studies, analyse data, and document findings (e.g., filter selection, fill volume assessments, compatibility tests).
- Analyse manufacturing data to improve process understanding and performance.
- Perform risk assessments for manufacturing processes.
- Design processes for sterile injectable products in various forms (e.g., liquid, lyophilized powder, pre-filled syringes).
- Support clinical trial preparation and ensure timely production of stability and clinical batches.
- Assist in process validation and ensure compliance with quality standards and regulations.
- Contribute to regulatory submissions and respond to authority queries.
- Investigate and resolve quality-related issues, such as deviations or complaints.
- Facilitate knowledge transfer from late-phase development to commercial production.
- Help improve departmental processes and ways of working.
Key Skills and Requirements:
- Experience in developing or manufacturing liquid drug products in the pharmaceutical industry.
- Familiarity with biopharmaceuticals is a plus.
- Knowledge of aseptic manufacturing processes, including vial, cartridge, and pre-filled syringe filling, is advantageous.
- Understanding of sterile drug product development, including components, process transfer, scale-up, and optimization, is beneficial.
For more information, please contact Jessica Taylor.
If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists visit the 'Contact Us' page.
Hobson Prior is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Hobson Prior is acting as an Employment Agency in relation to this vacancy.
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Drug Safety Administrator
Posted 6 days ago
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Job Description
Our client is a market leader within the Pharma Covigilance market. They are looking to recruit a Drug Safety Administrator who will be an active participant in meetings and assist the PV Manager in maintaining standard operating procedures or working practices. During their daily activities, the Drug Safety Administrator will be required to liaise with pharmaceutical companies and other business partners.
Daily tasks:
- Keeping the Pharmacovigilance Manager fully informed of problems and issues that may arise related to the product, adverse events, the patients, prescribers or the marketing authorisation holder.
- Processing selected case reports in the database.
- Checking all literature case reports have the appropriate AE terms assigned for MedDRA coding. Notifying the QPPV of cases where the appropriate MedDRA term cannot be identified independently.
- Reconciliation both with clients and/or with PV partners on behalf of clients (as required).
- Processing reports from any source in the drug safety database.
- Assessing adverse events and carry out listedness and causality assessments.
- Exchanging a PV case reference from the database with PV partners.
- Conducting follow-up investigation for direct reports from either patients or healthcare professionals.
- Maintaining Continued Professional Development in support of your role and responsibilities.
- Participate in various team meetings and liaise with other colleagues about on-going projects.
- Assist with documentation such as Working Practices and Standard Operating Procedures, where required.
- Develop a thorough knowledge of medicinal products and with regulations and guidelines within the industry.
- An organised, proactive person with excellent attention to detail.
- Excellent oral and written communication with proficiency in standard software programs.
Minimum Requirements:
- Life science or Bio medical graduate (1-2 years working experience desirable) or other allied healthcare professional.
Please note candidates will only be considered with the above skills and unfortunately this company cannot consider sponsorship, or a visa status that will need renewing.
Drug Safety Administrator
Posted 6 days ago
Job Viewed
Job Description
Our client is a market leader within the Pharma Covigilance market. They are looking to recruit a Drug Safety Administrator who will be an active participant in meetings and assist the PV Manager in maintaining standard operating procedures or working practices. During their daily activities, the Drug Safety Administrator will be required to liaise with pharmaceutical companies and other business partners.
Daily tasks:
- Keeping the Pharmacovigilance Manager fully informed of problems and issues that may arise related to the product, adverse events, the patients, prescribers or the marketing authorisation holder.
- Processing selected case reports in the database.
- Checking all literature case reports have the appropriate AE terms assigned for MedDRA coding. Notifying the QPPV of cases where the appropriate MedDRA term cannot be identified independently.
- Reconciliation both with clients and/or with PV partners on behalf of clients (as required).
- Processing reports from any source in the drug safety database.
- Assessing adverse events and carry out listedness and causality assessments.
- Exchanging a PV case reference from the database with PV partners.
- Conducting follow-up investigation for direct reports from either patients or healthcare professionals.
- Maintaining Continued Professional Development in support of your role and responsibilities.
- Participate in various team meetings and liaise with other colleagues about on-going projects.
- Assist with documentation such as Working Practices and Standard Operating Procedures, where required.
- Develop a thorough knowledge of medicinal products and with regulations and guidelines within the industry.
- An organised, proactive person with excellent attention to detail.
- Excellent oral and written communication with proficiency in standard software programs.
Minimum Requirements:
- Life science or Bio medical graduate (1-2 years working experience desirable) or other allied healthcare professional.
Please note candidates will only be considered with the above skills and unfortunately this company cannot consider sponsorship, or a visa status that will need renewing.