1,692 Drug Delivery Systems jobs in the United Kingdom
Senior Formulation Scientist - Novel Drug Delivery Systems
PL4 0AU Plymouth, South West
£70000 Annually
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Posted today
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Job Description
Our client, a highly respected pharmaceutical company, is seeking an experienced Senior Formulation Scientist to spearhead the development of innovative drug delivery systems. This is a fully remote opportunity, perfect for an individual seeking to leverage their expertise from anywhere within the UK.
As a Senior Formulation Scientist, you will be instrumental in designing, developing, and optimizing novel formulations for small molecules and biologics. Your work will focus on enhancing drug efficacy, improving patient compliance, and overcoming formulation challenges. You will lead projects from concept through to preclinical development, working closely with analytical development, DMPK, and manufacturing teams. This role demands a deep understanding of pharmaceutical sciences, a creative approach to problem-solving, and a commitment to advancing patient care.
Key Responsibilities:
As a Senior Formulation Scientist, you will be instrumental in designing, developing, and optimizing novel formulations for small molecules and biologics. Your work will focus on enhancing drug efficacy, improving patient compliance, and overcoming formulation challenges. You will lead projects from concept through to preclinical development, working closely with analytical development, DMPK, and manufacturing teams. This role demands a deep understanding of pharmaceutical sciences, a creative approach to problem-solving, and a commitment to advancing patient care.
Key Responsibilities:
- Design, develop, and optimize novel pharmaceutical formulations (e.g., oral, injectable, topical) for various therapeutic modalities.
- Investigate and apply advanced drug delivery technologies to improve bioavailability, stability, and targeted delivery.
- Characterize formulations using a range of analytical techniques (e.g., HPLC, dissolution, particle size analysis).
- Plan and execute formulation development studies, including pre-formulation, stability testing, and scale-up activities.
- Troubleshoot formulation challenges and identify appropriate solutions.
- Collaborate effectively with cross-functional teams, including analytical development, regulatory affairs, and manufacturing sciences.
- Prepare comprehensive reports, regulatory submission documents, and contribute to intellectual property filings.
- Stay current with scientific literature, industry trends, and new technologies in pharmaceutical formulation and drug delivery.
- Mentor junior scientists and provide technical guidance.
- Ensure compliance with GMP regulations and quality standards throughout the development process.
- Present research findings to internal stakeholders and at scientific conferences.
- Ph.D. or Master's degree in Pharmaceutical Sciences, Pharmaceutics, Chemistry, Chemical Engineering, or a related discipline.
- Minimum of 6 years of hands-on experience in pharmaceutical formulation development.
- Proven expertise in developing various dosage forms and understanding of drug delivery principles.
- Proficiency in common analytical techniques used for formulation characterization.
- Experience with experimental design and data analysis.
- Strong understanding of GMP principles and regulatory requirements.
- Excellent problem-solving skills and the ability to think creatively and innovatively.
- Strong written and verbal communication skills, with the ability to present complex information clearly.
- Ability to work independently and collaboratively in a remote setting.
- Experience with biologics formulation is a significant advantage.
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0
Senior Formulation Scientist - Drug Development
M1 4BE Manchester, North West
£60000 Annually
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Posted 1 day ago
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Job Description
Our client, a leading pharmaceutical company, is seeking a highly experienced Senior Formulation Scientist to join their Research and Development team in Manchester, Greater Manchester, UK . This role is critical in the development of innovative drug delivery systems and solid dosage forms. You will lead the formulation development process from early-stage research through to clinical trial material production and potentially commercialisation. Key responsibilities include designing and executing experiments to develop stable, effective, and patient-compliant pharmaceutical formulations. This involves extensive hands-on laboratory work, including pre-formulation studies, excipient screening, process development, and optimisation. You will utilise a range of analytical techniques to characterise formulations and drug substances. Collaboration with analytical development, solid-state chemistry, and project management teams is essential to ensure project timelines are met. The Senior Formulation Scientist will also be responsible for troubleshooting formulation challenges, providing scientific expertise, and documenting all experimental work thoroughly. Mentoring junior scientists and contributing to the scientific direction of the department are also key aspects of this role. A deep understanding of pharmaceutical sciences, drug delivery principles, and regulatory requirements (e.g., GMP) is mandatory. This is an exciting opportunity to contribute to the advancement of novel therapeutics and make a real difference to patient lives.
Responsibilities:
Responsibilities:
- Lead the development of new pharmaceutical formulations for various therapeutic areas.
- Design, conduct, and interpret pre-formulation and formulation development studies.
- Develop and optimise manufacturing processes for solid dosage forms (e.g., tablets, capsules).
- Perform characterisation of raw materials, intermediates, and finished products.
- Troubleshoot formulation and process-related issues.
- Prepare scientific reports, development protocols, and regulatory submission documents.
- Collaborate with cross-functional teams including analytical, QA/QC, and regulatory affairs.
- Stay updated on the latest advancements in pharmaceutical formulation and drug delivery technologies.
- Mentor and guide junior members of the formulation team.
- Ensure all laboratory activities comply with Good Manufacturing Practices (GMP).
- PhD or Master's degree in Pharmaceutical Sciences, Chemistry, or a related discipline.
- Minimum of 5 years of experience in pharmaceutical formulation development.
- Proven track record in developing solid oral dosage forms.
- Hands-on experience with laboratory equipment for formulation and analysis (e.g., HPLC, dissolution apparatus, rheometers).
- Strong knowledge of excipients, drug solubility enhancement techniques, and stability testing.
- Familiarity with GMP guidelines and regulatory requirements.
- Excellent scientific writing, presentation, and problem-solving skills.
- Ability to work independently and collaboratively in a team environment.
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Lead Formulation Scientist - Drug Development
ST1 2BE Staffordshire, West Midlands
£60000 Annually
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Posted 2 days ago
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Our client, a dynamic pharmaceutical company renowned for its commitment to developing life-changing medicines, is seeking an experienced Lead Formulation Scientist to join their R&D team in Stoke-on-Trent, Staffordshire, UK . This role offers an exciting opportunity to drive the formulation development of novel drug products from early-stage research through to clinical manufacturing. The successful candidate will play a crucial role in designing, optimizing, and scaling up innovative drug delivery systems, ensuring product quality, stability, and efficacy.
Responsibilities:
Responsibilities:
- Lead the formulation development of various dosage forms, including oral solids, injectables, and topical preparations.
- Design and execute pre-formulation studies to understand drug substance properties and their impact on formulation.
- Develop and optimize formulations using a range of excipients and processing techniques.
- Conduct stability studies to assess product shelf-life and storage conditions.
- Investigate and troubleshoot formulation-related issues encountered during development and manufacturing.
- Collaborate closely with analytical development, manufacturing sciences, and regulatory affairs teams.
- Prepare comprehensive formulation development reports, protocols, and CMC documentation for regulatory submissions.
- Evaluate and implement new formulation technologies and analytical methods.
- Manage external contract research organisations (CROs) for specific formulation development activities.
- Mentor and guide junior formulation scientists, fostering scientific excellence and professional growth.
- Stay updated with the latest advancements in pharmaceutical formulation and drug delivery.
- PhD or MSc in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related discipline.
- Minimum of 5-7 years of hands-on experience in pharmaceutical formulation development.
- Proven expertise in developing multiple dosage forms (e.g., tablets, capsules, sterile injectables).
- Strong understanding of drug delivery principles, excipient functionality, and manufacturing processes.
- Experience with analytical techniques relevant to formulation characterization (e.g., HPLC, dissolution testing, particle size analysis).
- Proficiency in GMP/GLP environments and experience with regulatory guidelines (e.g., ICH).
- Excellent problem-solving skills and a methodical approach to scientific investigation.
- Strong project management skills and the ability to manage multiple priorities effectively.
- Outstanding communication and interpersonal skills, with the ability to present complex data clearly.
- Experience in leading scientific projects or teams is highly desirable.
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2
Senior Formulation Scientist - Drug Development
OX1 3QG Oxford, South East
£65000 Annually
WhatJobs
Posted 15 days ago
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Job Description
Our client, a groundbreaking pharmaceutical company at the forefront of medical innovation, is seeking a highly experienced Senior Formulation Scientist to join their dynamic research and development team. This is a fully remote position, offering an exceptional opportunity to contribute to the development of novel drug delivery systems and pharmaceutical products from your home laboratory or approved remote workspace. You will play a critical role in designing, optimizing, and characterizing drug formulations to meet stringent efficacy, safety, and regulatory standards.
Responsibilities:
Responsibilities:
- Lead the design, development, and optimization of innovative drug formulations (e.g., oral solid dosage forms, injectables, topical applications) for various therapeutic areas.
- Conduct pre-formulation studies to understand drug-excipient compatibility, physicochemical properties, and stability.
- Develop and validate analytical methods for characterizing formulations and assessing drug release profiles.
- Oversee formulation scale-up activities, ensuring successful technology transfer from lab to pilot and manufacturing scales.
- Prepare comprehensive technical documentation, including formulation development reports, analytical method validation reports, and regulatory submission documents.
- Collaborate closely with cross-functional teams, including analytical chemistry, process development, quality assurance, and regulatory affairs.
- Troubleshoot formulation challenges and implement robust solutions to ensure product quality and performance.
- Stay abreast of the latest advancements in pharmaceutical formulation science, drug delivery technologies, and relevant regulatory guidelines.
- Mentor and guide junior scientists, fostering a culture of scientific excellence and continuous learning.
- Manage external contract research organizations (CROs) for specific formulation development activities, ensuring project timelines and deliverables are met.
- PhD or Master's degree in Pharmaceutical Sciences, Pharmaceutics, Chemical Engineering, or a related discipline.
- Minimum of 7 years of hands-on experience in pharmaceutical formulation development, with a proven track record in bringing drug products from concept to clinical trial stages.
- In-depth knowledge of various drug delivery systems and formulation techniques.
- Proficiency in relevant analytical techniques (e.g., HPLC, GC, DSC, XRPD) for formulation characterization.
- Strong understanding of pharmaceutical manufacturing processes and GMP requirements.
- Experience with regulatory guidelines (e.g., ICH, FDA, EMA) pertaining to drug development.
- Excellent problem-solving skills, with a keen attention to detail and the ability to interpret complex data.
- Exceptional written and verbal communication skills, with the ability to effectively present scientific findings.
- Proven ability to work independently and manage multiple projects in a remote research environment.
- Experience with statistical analysis software and design of experiments (DoE) is advantageous.
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3
Principal Formulation Scientist - Drug Development
NG1 6AE Nottingham, East Midlands
£80000 Annually
WhatJobs
Posted 25 days ago
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Job Description
Our client, a leading pharmaceutical company dedicated to advancing healthcare through innovative drug development, is seeking an experienced and highly skilled Principal Formulation Scientist to join their dynamic R&D team in Nottingham, Nottinghamshire, UK . This critical role will involve leading the development of novel drug delivery systems and innovative formulations for a diverse pipeline of pharmaceutical products. You will be at the forefront of designing, optimizing, and scaling up formulations, ensuring product efficacy, stability, and bioavailability. The ideal candidate will possess a deep understanding of pharmaceutical sciences, particularly in pre-formulation, formulation development, and manufacturing processes. Responsibilities include conducting pre-formulation studies, designing and executing experiments for solid dosage forms, sterile injectables, or other relevant delivery routes, and characterizing formulation performance. You will lead the troubleshooting of formulation challenges and provide expert scientific guidance to project teams. The Principal Formulation Scientist will play a key role in the transition of formulations from laboratory scale to clinical manufacturing and beyond. Collaboration with cross-functional teams, including analytical development, DMPK, regulatory affairs, and manufacturing, is essential. You will also contribute to the scientific strategy of the formulation department, stay abreast of emerging technologies, and potentially mentor junior scientists. A strong publication record and experience with intellectual property development are desirable. This hybrid role offers a blend of essential lab-based work and remote strategic planning and analysis, providing a balanced and productive work environment. This is an excellent opportunity to contribute to life-changing medicines within a supportive and scientifically driven organization in Nottingham .
Qualifications:
Qualifications:
- Ph.D. in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related field
- Minimum of 7 years of progressive experience in pharmaceutical formulation development
- Proven expertise in developing various dosage forms (e.g., oral solids, injectables, topical)
- Strong understanding of pre-formulation, excipient selection, and drug-excipient compatibility
- Hands-on experience with formulation characterization techniques (e.g., DSC, TGA, XRPD, dissolution)
- Experience with pilot-scale formulation manufacturing and technology transfer
- Knowledge of GMP guidelines and regulatory requirements for drug development
- Excellent problem-solving, analytical, and critical thinking skills
- Strong project management and organizational abilities
- Effective communication and interpersonal skills for cross-functional collaboration
- Ability to mentor junior scientists and contribute to scientific strategy
- Experience with specific therapeutic areas is a plus
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4
Pharmaceutical Formulation Scientist - Drug Development
MK9 2EZ Milton Keynes, South East
£60000 Annually
WhatJobs
Posted 25 days ago
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Job Description
Our client, a leading pharmaceutical company dedicated to advancing healthcare solutions, is seeking a skilled and innovative Pharmaceutical Formulation Scientist to join their research and development team in Milton Keynes, Buckinghamshire, UK . This role is pivotal in the early-stage development of novel drug formulations, contributing to the creation of effective and patient-centric medicines. The ideal candidate will possess a strong background in pharmaceutical sciences, with hands-on experience in formulation development and characterization. Responsibilities will include:
- Designing, developing, and optimizing oral solid dosage forms (tablets, capsules) and potentially other dosage forms.
- Conducting pre-formulation studies to understand the physicochemical properties of active pharmaceutical ingredients (APIs) and excipients.
- Evaluating and selecting appropriate excipients to achieve desired drug release profiles and stability.
- Utilizing various laboratory techniques for formulation preparation and characterization (e.g., particle size analysis, dissolution testing, differential scanning calorimetry).
- Developing and validating analytical methods for drug product testing.
- Conducting stability studies to assess the shelf-life and performance of formulations under various conditions.
- Troubleshooting formulation challenges and proposing innovative solutions.
- Collaborating with analytical development, process development, and regulatory affairs teams.
- Documenting experimental procedures, results, and reports in accordance with company standards and regulatory guidelines.
- Staying current with scientific literature and industry trends in pharmaceutical formulation and drug delivery.
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5
Senior Formulation Scientist - Innovative Drug Development
LE2 0AA Leicester, East Midlands
£55000 Annually
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Posted 9 days ago
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Job Description
Our client, a leading innovator in pharmaceutical research and development, is seeking a highly skilled and motivated Senior Formulation Scientist to join their dynamic team. This is an exciting opportunity to contribute to the development of cutting-edge therapeutic agents from pre-clinical stages through to clinical trials. The role will involve extensive laboratory work, data analysis, and collaboration with cross-functional teams.
Key Responsibilities:
Key Responsibilities:
- Design, develop, and optimize novel drug delivery systems and formulations for various routes of administration (e.g., oral, injectable, topical).
- Conduct pre-formulation studies, including API characterization, solubility enhancement, and stability assessment.
- Perform compatibility studies and develop analytical methods for drug substance and drug product characterization.
- Utilize a range of formulation technologies and equipment, including granulation, coating, lyophilization, and sterile manufacturing processes.
- Execute experiments meticulously, document all findings accurately in laboratory notebooks and reports, and present results to project teams and management.
- Troubleshoot formulation challenges and propose innovative solutions.
- Collaborate closely with analytical chemists, process engineers, and clinical development teams to ensure successful project progression.
- Stay abreast of the latest scientific literature, regulatory guidelines, and industry trends in pharmaceutical formulation.
- Contribute to the preparation of regulatory submission documents (e.g., IND, NDA).
- PhD or MSc in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related field.
- Minimum of 5 years of relevant experience in pharmaceutical formulation development, preferably within an R&D setting.
- Proven track record in developing various dosage forms, with a strong understanding of formulation science principles.
- Hands-on experience with laboratory equipment for formulation development and characterization.
- Proficiency in relevant analytical techniques (e.g., HPLC, GC, DSC, TGA, XRPD).
- Excellent understanding of Good Manufacturing Practice (GMP) and regulatory requirements.
- Strong problem-solving skills, attention to detail, and ability to work independently and as part of a team.
- Effective communication and interpersonal skills.
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Lead Clinical Research Scientist - Oncology Drug Development
PO1 3DT Portsmouth, South East
£70000 Annually
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Posted 4 days ago
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Job Description
Our client, a pioneering pharmaceutical company at the forefront of innovative cancer therapies, is seeking a highly accomplished Lead Clinical Research Scientist to join their fully remote R&D team. This critical role will focus on the strategic design, execution, and analysis of clinical trials for novel oncology therapeutics. You will be instrumental in driving the drug development pipeline forward, ensuring scientific rigor and compliance with all regulatory standards. The ideal candidate will possess a PhD or equivalent in a relevant life science discipline, coupled with extensive experience in clinical trial management, data analysis, and interpretation within the oncology field. Responsibilities include developing clinical trial protocols, overseeing study conduct, collaborating with cross-functional teams (including biostatistics, data management, and regulatory affairs), and authoring clinical study reports and regulatory submissions. You will be expected to provide scientific leadership, mentor junior researchers, and stay abreast of the latest advancements in cancer biology, pharmacodynamics, and clinical trial methodologies. This position requires exceptional analytical skills, a strong understanding of statistical principles, and the ability to communicate complex scientific information effectively to both scientific and non-scientific audiences. Working in a fully remote capacity, you must demonstrate excellent organizational skills, proactivity, and the ability to manage multiple projects simultaneously while maintaining high standards of quality and compliance. You will play a key role in shaping the future of cancer treatment, contributing to life-saving therapies. This is a significant opportunity to join a world-class organisation and make a profound impact on patient lives globally. The role demands a deep understanding of both pre-clinical and clinical development phases, with a focus on translating scientific discoveries into effective treatments. Expertise in specific oncology sub-specialties, such as immunotherapy or targeted therapy, is highly desirable. You will be at the cutting edge of pharmaceutical research, contributing to a culture of innovation and scientific excellence.
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7
Senior Clinical Research Scientist - Oncology Drug Development
M1 1AA Manchester, North West
£70000 Annually
WhatJobs
Posted 8 days ago
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Job Description
Our client, a leading biopharmaceutical innovator, is seeking a highly motivated Senior Clinical Research Scientist to join their cutting-edge oncology research team. This fully remote position offers the unique opportunity to contribute significantly to the development of novel cancer therapies from anywhere in the UK. You will be at the forefront of scientific advancement, playing a pivotal role in the design, execution, and interpretation of clinical trials that have the potential to transform patient lives.
Key Responsibilities:
Qualifications and Experience:
This is a crucial role for an accomplished scientist passionate about making a difference in the fight against cancer. Join our innovative client and shape the future of oncology treatments.
Key Responsibilities:
- Design and develop clinical trial protocols for oncology assets, ensuring scientific rigor and regulatory compliance.
- Oversee the execution of clinical studies, providing scientific and medical expertise to cross-functional teams.
- Analyze and interpret complex clinical trial data, including efficacy and safety endpoints.
- Collaborate with regulatory affairs, statistics, and medical writing teams to prepare submissions and publications.
- Stay abreast of the latest scientific advancements, emerging trends, and competitive landscape in oncology drug development.
- Identify and engage with key opinion leaders (KOLs) and investigators in the field.
- Contribute to the strategic planning and decision-making processes for the oncology portfolio.
- Develop and present scientific data internally and externally at conferences and meetings.
- Ensure adherence to Good Clinical Practice (GCP) guidelines and all relevant regulations.
- Mentor junior scientists and contribute to the growth of the research department.
Qualifications and Experience:
- Ph.D. or M.D. in a relevant life science discipline (e.g., Oncology, Immunology, Pharmacology).
- Minimum of 5-7 years of experience in clinical research and drug development, with a significant focus on oncology.
- Demonstrated experience in designing and managing complex clinical trials (Phase I-III).
- In-depth knowledge of oncology disease areas, drug mechanisms, and current treatment paradigms.
- Strong understanding of regulatory requirements (FDA, EMA) and GCP.
- Excellent analytical, statistical interpretation, and problem-solving skills.
- Exceptional written and verbal communication skills, with a proven track record of scientific publications and presentations.
- Ability to work effectively in a remote, fast-paced, and collaborative environment.
- Experience with data management systems and statistical analysis software is a plus.
- Strong leadership potential and ability to influence cross-functional teams.
This is a crucial role for an accomplished scientist passionate about making a difference in the fight against cancer. Join our innovative client and shape the future of oncology treatments.
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8
Principal Clinical Research Scientist - Oncology Drug Development
G1 1AA Glasgow, Scotland
£90000 Annually
WhatJobs
Posted 15 days ago
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Job Description
Our client, a leading pharmaceutical innovator, is seeking a highly accomplished Principal Clinical Research Scientist to spearhead critical oncology drug development programs. This role requires a deep scientific understanding of cancer biology, extensive experience in clinical trial design and execution, and a passion for bringing life-changing therapies to patients. You will collaborate with world-class researchers and clinicians to advance novel treatments from early-stage research through to regulatory submission.
Responsibilities:
Responsibilities:
- Lead the scientific strategy and design of Phase I-III clinical trials for novel oncology therapeutics.
- Oversee the development of clinical protocols, investigator brochures, and other essential study documents.
- Provide scientific and clinical expertise to cross-functional teams, including clinical operations, data management, regulatory affairs, and biomarker development.
- Analyze and interpret complex clinical trial data, translating findings into strategic recommendations for drug development.
- Prepare high-quality scientific publications, abstracts, and presentations for key medical conferences and journals.
- Engage with key opinion leaders (KOLs) in oncology to gather insights and foster collaboration.
- Contribute to regulatory submissions (e.g., IND, NDA) by preparing relevant clinical sections.
- Stay abreast of the latest advancements in oncology research, emerging therapeutic modalities, and competitive landscape.
- Mentor and guide junior scientists and clinical development professionals.
- Ensure all clinical research activities comply with GCP, regulatory guidelines, and company policies.
- Ph.D. or M.D. in a relevant life sciences discipline (e.g., Oncology, Immunology, Molecular Biology).
- Minimum of 10 years of experience in clinical drug development, with a strong focus on oncology.
- Demonstrated success in designing and leading complex clinical trials.
- Expertise in cancer biology, tumor microenvironment, and current therapeutic strategies.
- In-depth knowledge of GCP, regulatory requirements, and clinical trial methodologies.
- Proven ability to analyze and interpret clinical data effectively.
- Excellent scientific writing and communication skills, with a track record of publications and presentations.
- Strong leadership capabilities and experience working in a matrixed environment.
- Ability to travel to Glasgow, Scotland, UK as required for key meetings and site visits.
- Experience with immuno-oncology and targeted therapies is highly desirable.
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