6,821 Drug Discovery Scientist jobs in the United Kingdom
Principal Drug Discovery Scientist
EH1 2LG Edinburgh, Scotland
£90000 Annually
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Posted 1 day ago
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Job Description
Our client is a leading biopharmaceutical company at the forefront of developing novel therapies for challenging diseases. We are seeking a highly innovative and experienced Principal Drug Discovery Scientist to lead key research programs. This role is fully remote, offering an exceptional opportunity for talented individuals to contribute to groundbreaking science from the convenience of their own location. You will be responsible for designing and executing cutting-edge research strategies, driving lead optimization, and advancing drug candidates through the preclinical pipeline. Your expertise will be vital in translating scientific insights into potential life-saving medicines.
Key Responsibilities:
Key Responsibilities:
- Lead and design innovative drug discovery projects from target validation through to preclinical candidate nomination.
- Develop and implement robust experimental strategies utilizing state-of-the-art biological assays and techniques.
- Critically evaluate and interpret complex biological data, identifying key trends and making informed decisions.
- Collaborate closely with medicinal chemists, pharmacologists, DMPK scientists, and other R&D functions.
- Manage external research collaborations and CRO relationships effectively.
- Stay abreast of the latest scientific advancements and emerging technologies in relevant therapeutic areas and drug discovery.
- Mentor and provide scientific guidance to junior scientists and research associates.
- Contribute to the strategic planning and prioritization of the drug discovery portfolio.
- Prepare high-quality research reports, manuscripts for publication, and presentations for internal and external audiences.
- Ensure compliance with all laboratory safety and regulatory guidelines.
- Ph.D. in Molecular Biology, Pharmacology, Biochemistry, Immunology, or a related life science discipline.
- A minimum of 10 years of post-doctoral research experience in drug discovery, preferably within the pharmaceutical or biotech industry.
- Proven track record of successfully advancing drug candidates into preclinical development.
- Extensive experience in assay development, target validation, and small molecule/biologics discovery.
- Expertise in specific therapeutic areas (e.g., oncology, immunology, CNS) is highly desirable.
- Strong understanding of medicinal chemistry, pharmacokinetics, and pharmacodynamics principles.
- Excellent analytical, problem-solving, and critical-thinking skills.
- Exceptional communication, presentation, and interpersonal skills.
- Demonstrated leadership capabilities and experience mentoring scientific teams.
- Proven ability to manage complex projects and drive results in a fast-paced environment.
- Experience working in a fully remote R&D setting is essential.
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0
Principal Drug Discovery Scientist
PL4 0BG Plymouth, South West
£75000 Annually
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Posted 5 days ago
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Job Description
Our client, a leading pharmaceutical innovator, is looking for a highly accomplished Principal Drug Discovery Scientist to spearhead critical research programs in Plymouth, Devon, UK . This pivotal role involves leading the identification, validation, and optimization of novel therapeutic targets and drug candidates across a range of disease areas. You will be instrumental in designing and executing cutting-edge discovery strategies, leveraging your deep understanding of medicinal chemistry, pharmacology, and molecular biology. The ideal candidate will have a PhD in a relevant life science discipline (e.g., Pharmacology, Biochemistry, Medicinal Chemistry) and a proven track record of successfully advancing drug candidates from early discovery through to preclinical development. You will manage a team of talented scientists, foster a culture of innovation, and collaborate extensively with internal and external partners. This position requires exceptional leadership qualities, strategic thinking, and a comprehensive knowledge of the drug discovery process. Responsibilities include:
Qualifications:
Join our client’s dynamic team and contribute to the development of life-changing medicines.
- Designing and leading integrated drug discovery projects.
- Identifying and validating novel therapeutic targets.
- Developing and optimizing small molecule drug candidates.
- Managing a team of research scientists and providing scientific mentorship.
- Collaborating with cross-functional teams including DMPK, toxicology, and clinical development.
- Establishing and maintaining relationships with key academic and industry partners.
- Overseeing the interpretation of complex biological and chemical data.
- Ensuring the highest standards of scientific rigor and ethical conduct.
- Contributing to the company's overall R&D strategy.
- Presenting research findings at internal and external scientific forums.
Qualifications:
- PhD in Pharmacology, Biochemistry, Medicinal Chemistry, or a related field.
- Extensive experience (10+ years) in pharmaceutical drug discovery.
- Demonstrated success in bringing drug candidates into preclinical or clinical development.
- Expertise in target identification and validation, lead generation, and lead optimization.
- Proven experience in managing and leading scientific teams.
- Strong understanding of biology, chemistry, and pharmacokinetics.
- Excellent communication, presentation, and interpersonal skills.
- Strategic thinker with strong problem-solving capabilities.
- Experience with biologics or other therapeutic modalities is a plus.
Join our client’s dynamic team and contribute to the development of life-changing medicines.
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1
Principal Drug Discovery Scientist
OX1 2JD Oxford, South East
£80000 Annually
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Posted 10 days ago
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Job Description
Our client, a cutting-edge biopharmaceutical company renowned for its innovative approach to drug discovery, is seeking a highly experienced Principal Drug Discovery Scientist. This is a fully remote position, enabling you to drive significant advancements in therapeutic research from your dedicated home office. You will be at the forefront of identifying and validating novel drug targets and advancing potential therapeutics through the early stages of development.
As a Principal Scientist, you will lead ambitious research projects, conceptualize and execute groundbreaking experiments, and interpret complex biological and chemical data to shape the company's pipeline. Your role will involve strategic direction-setting for discovery programs, mentoring talented scientists, and fostering collaboration across diverse scientific disciplines, including medicinal chemistry, biology, and pharmacology. You will play a key role in advancing our client's mission to develop life-changing medicines, supporting their research initiatives connected to the vibrant scientific community in Oxford, Oxfordshire, UK .
Key Responsibilities:
The ideal candidate will possess a Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related discipline, with a minimum of 7-10 years of relevant experience in the pharmaceutical or biotechnology industry, focused on small molecule or biologic drug discovery. A proven track record of successful project leadership and delivering preclinical candidates is essential. Expertise in specific therapeutic areas (e.g., oncology, neurodegenerative diseases, infectious diseases) is highly valued. Excellent leadership, communication, and problem-solving skills are critical. The ability to work independently, drive scientific innovation, and contribute effectively within a remote research environment is paramount.
As a Principal Scientist, you will lead ambitious research projects, conceptualize and execute groundbreaking experiments, and interpret complex biological and chemical data to shape the company's pipeline. Your role will involve strategic direction-setting for discovery programs, mentoring talented scientists, and fostering collaboration across diverse scientific disciplines, including medicinal chemistry, biology, and pharmacology. You will play a key role in advancing our client's mission to develop life-changing medicines, supporting their research initiatives connected to the vibrant scientific community in Oxford, Oxfordshire, UK .
Key Responsibilities:
- Leading the design and execution of innovative drug discovery projects.
- Identifying and validating novel therapeutic targets using a range of biological and biochemical techniques.
- Developing and implementing high-throughput screening (HTS) campaigns and hit-to-lead optimization strategies.
- Interpreting complex biological data and translating findings into actionable research plans.
- Mentoring and guiding a team of drug discovery scientists.
- Collaborating closely with medicinal chemists, pharmacologists, and other R&D professionals.
- Contributing to the strategic planning and prioritization of the company's R&D pipeline.
- Preparing compelling research reports, scientific publications, and patent applications.
- Presenting research findings effectively to internal stakeholders and at scientific conferences.
- Staying current with the latest advancements in drug discovery technologies and therapeutic modalities.
The ideal candidate will possess a Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related discipline, with a minimum of 7-10 years of relevant experience in the pharmaceutical or biotechnology industry, focused on small molecule or biologic drug discovery. A proven track record of successful project leadership and delivering preclinical candidates is essential. Expertise in specific therapeutic areas (e.g., oncology, neurodegenerative diseases, infectious diseases) is highly valued. Excellent leadership, communication, and problem-solving skills are critical. The ability to work independently, drive scientific innovation, and contribute effectively within a remote research environment is paramount.
This advertiser has chosen not to accept applicants from your region.
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Senior Drug Discovery Scientist
BD7 1GT Bradford, Yorkshire and the Humber
£65000 Annually
WhatJobs
Posted 18 days ago
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Job Description
Our client, a cutting-edge biotechnology company at the forefront of medical innovation, is seeking a highly motivated Senior Drug Discovery Scientist to join their esteemed research team in Bradford, West Yorkshire, UK . This hybrid role is integral to the advancement of novel therapeutic agents. You will be responsible for designing, executing, and interpreting complex experiments to identify and validate new drug targets and develop small molecule or biologic drug candidates. The ideal candidate will possess a strong scientific background in molecular biology, pharmacology, or a related discipline, coupled with significant hands-on experience in drug discovery. This role requires a blend of innovative thinking, rigorous experimental design, and a deep commitment to translating scientific breakthroughs into life-changing medicines.
Key Responsibilities:
Key Responsibilities:
- Design and implement innovative research strategies to identify and validate novel drug targets for unmet medical needs.
- Develop and optimise assays for high-throughput screening (HTS) and lead optimisation.
- Conduct experiments to characterise the mechanism of action of drug candidates and assess their efficacy in relevant preclinical models.
- Utilise a range of molecular biology, cell biology, and biochemical techniques to investigate disease pathways and therapeutic interventions.
- Analyse and interpret complex experimental data, draw robust conclusions, and present findings clearly to scientific teams and leadership.
- Collaborate effectively with cross-functional teams, including medicinal chemistry, DMPK, and toxicology, to advance drug candidates through the discovery pipeline.
- Stay current with the latest scientific literature, emerging technologies, and therapeutic trends in relevant disease areas.
- Contribute to the preparation of scientific publications, presentations, and patent applications.
- Mentor junior scientists and contribute to a positive and collaborative research environment.
- Manage external collaborations and CRO relationships as needed.
- Ensure all research activities are conducted in compliance with relevant ethical guidelines and safety protocols.
- PhD in Molecular Biology, Pharmacology, Biochemistry, or a related life science discipline.
- Minimum of 5 years of relevant post-doctoral or industry experience in drug discovery.
- Proven track record in identifying and validating drug targets and/or developing small molecule or biologic therapeutics.
- Extensive experience with assay development, screening, and compound evaluation.
- Strong understanding of drug discovery processes and preclinical development.
- Proficiency in relevant biological techniques, including cell culture, molecular cloning, protein expression and purification, and biochemical assays.
- Excellent data analysis and interpretation skills, with experience using relevant software.
- Strong written and verbal communication skills, with the ability to present complex scientific information effectively.
- Ability to work independently and as part of a multidisciplinary team in a hybrid setting.
- Demonstrated creativity, problem-solving skills, and a passion for scientific innovation.
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3
Lead Drug Discovery Scientist (Remote)
CB2 1AA Cambridge, Eastern
£70000 Annually
WhatJobs
Posted 4 days ago
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Job Description
Our client, a world-renowned pharmaceutical company at the forefront of therapeutic innovation, is seeking an exceptional Lead Drug Discovery Scientist to join their elite research team. This is a critical, fully remote position, offering the opportunity to shape the future of medicine from your home office. You will drive the identification and validation of novel drug targets and lead the early-stage development of groundbreaking therapies.
As a Lead Drug Discovery Scientist, you will be responsible for conceptualizing, designing, and executing innovative research projects aimed at discovering new medicines. You will lead a multidisciplinary team of scientists, fostering a collaborative and high-performance research environment. Your expertise will span across target identification, validation, lead generation, and early-stage optimization. You will play a pivotal role in defining project strategies, troubleshooting complex scientific challenges, and ensuring the timely progression of drug candidates through the discovery pipeline.
The ideal candidate will possess a PhD in a relevant scientific discipline (e.g., Pharmacology, Biochemistry, Molecular Biology, Medicinal Chemistry) with extensive experience in drug discovery within the pharmaceutical industry. You must demonstrate a strong track record of scientific leadership, project management, and the successful progression of drug candidates. Exceptional critical thinking, problem-solving abilities, and a deep understanding of disease biology and pharmacology are essential. Excellent communication and interpersonal skills are paramount for effective collaboration within a remote setting and with external partners.
Key Responsibilities:
As a Lead Drug Discovery Scientist, you will be responsible for conceptualizing, designing, and executing innovative research projects aimed at discovering new medicines. You will lead a multidisciplinary team of scientists, fostering a collaborative and high-performance research environment. Your expertise will span across target identification, validation, lead generation, and early-stage optimization. You will play a pivotal role in defining project strategies, troubleshooting complex scientific challenges, and ensuring the timely progression of drug candidates through the discovery pipeline.
The ideal candidate will possess a PhD in a relevant scientific discipline (e.g., Pharmacology, Biochemistry, Molecular Biology, Medicinal Chemistry) with extensive experience in drug discovery within the pharmaceutical industry. You must demonstrate a strong track record of scientific leadership, project management, and the successful progression of drug candidates. Exceptional critical thinking, problem-solving abilities, and a deep understanding of disease biology and pharmacology are essential. Excellent communication and interpersonal skills are paramount for effective collaboration within a remote setting and with external partners.
Key Responsibilities:
- Lead and manage early-stage drug discovery projects from target identification through to candidate selection.
- Design and implement innovative research strategies to identify and validate novel therapeutic targets.
- Oversee the execution of experiments using a range of biochemical, cellular, and pharmacological assays.
- Mentor and guide a team of research scientists, fostering a culture of scientific excellence and collaboration.
- Collaborate with chemists, biologists, and translational scientists to advance drug candidates.
- Analyze and interpret complex experimental data, making critical decisions on project direction.
- Prepare research proposals, reports, and presentations for internal and external stakeholders.
- Contribute to the strategic planning and portfolio management of the drug discovery unit.
- Stay abreast of scientific literature and emerging technologies in relevant therapeutic areas.
- PhD in Pharmacology, Biochemistry, Molecular Biology, Chemistry, or a related field.
- 10+ years of progressive experience in pharmaceutical drug discovery, with a focus on small molecules or biologics.
- Demonstrated success in leading and delivering drug discovery projects.
- Deep understanding of disease mechanisms and target validation strategies.
- Proficiency in a range of drug discovery techniques and assay development.
- Strong project management skills and experience managing multidisciplinary teams.
- Excellent critical thinking, analytical, and problem-solving abilities.
- Exceptional written and verbal communication skills, essential for effective remote leadership.
- Proven ability to publish in high-impact journals and present at scientific conferences.
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4
Principal Drug Discovery Scientist (Oncology)
G1 1AA Glasgow, Scotland
£70000 Annually
WhatJobs
Posted 9 days ago
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Job Description
Our client, a leading pharmaceutical innovator, is seeking a highly accomplished Principal Drug Discovery Scientist to spearhead critical research initiatives within their oncology division, based in **Glasgow, Scotland, UK**. This role offers a unique opportunity to drive the discovery and development of novel therapeutics targeting unmet needs in cancer treatment. You will lead a multidisciplinary team of scientists, fostering a collaborative and innovative research environment. Responsibilities will include designing and executing complex experiments, analyzing and interpreting large datasets, and contributing to the strategic direction of the oncology pipeline. The ideal candidate will possess a PhD in a relevant scientific discipline (e.g., Molecular Biology, Biochemistry, Pharmacology), coupled with extensive post-doctoral and industry experience in small molecule or biologic drug discovery, specifically within oncology. A proven track record of successful project leadership, a deep understanding of cancer biology, and expertise in modern drug discovery technologies are essential. You will be responsible for managing internal and external collaborations, presenting research findings at international conferences, and contributing to regulatory submissions. This is a hybrid role, requiring a balance of in-office collaboration and independent research. Key responsibilities include:
- Leading the design and execution of early-stage drug discovery projects in oncology.
- Mentoring and managing a team of research scientists.
- Developing and validating novel assays for target engagement and efficacy.
- Translating biological insights into actionable drug discovery strategies.
- Collaborating with medicinal chemists, DMPK scientists, and translational researchers.
- Analyzing and presenting complex experimental data to internal and external stakeholders.
- Contributing to the strategic planning and portfolio management of the oncology R&D pipeline.
- Staying abreast of the latest advancements in cancer biology and drug discovery.
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5
Principal Drug Discovery Scientist (Oncology)
SW1A 0AA London, London
£85000 Annually
WhatJobs
Posted 10 days ago
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Job Description
Our client, a world-renowned pharmaceutical research organization, is seeking a highly accomplished and innovative Principal Drug Discovery Scientist specializing in Oncology to join their cutting-edge research team. This is a fully remote position, offering an unparalleled opportunity to contribute to life-saving therapies from your dedicated home laboratory or office space. The successful candidate will lead critical projects, driving the discovery and development of novel anti-cancer agents. Key Responsibilities:
- Lead the design and execution of innovative drug discovery programs targeting various oncological pathways and mechanisms.
- Oversee the identification, validation, and optimization of novel drug targets and lead compounds within the oncology portfolio.
- Manage research projects from target identification through to preclinical candidate selection, ensuring scientific rigor and timely delivery.
- Utilize expertise in cancer biology, medicinal chemistry, and pharmacology to guide experimental strategies and interpret complex data.
- Supervise and mentor a team of talented research scientists and associates, fostering a collaborative and high-performance research environment.
- Develop and implement state-of-the-art assays and screening methodologies relevant to oncology drug discovery.
- Stay abreast of the latest scientific literature, emerging technologies, and competitive landscape in oncology drug development.
- Prepare high-quality scientific reports, publications, and presentations for internal stakeholders and external scientific conferences.
- Collaborate effectively with internal and external partners, including academic institutions and contract research organizations (CROs).
- Contribute to strategic planning and pipeline prioritization for the oncology drug discovery franchise.
- PhD in Cancer Biology, Molecular Pharmacology, Medicinal Chemistry, or a closely related field.
- A minimum of 10 years of progressive drug discovery experience in the pharmaceutical or biotechnology industry, with a strong focus on oncology.
- Demonstrated success in leading drug discovery projects from inception to candidate nomination.
- Expertise in key areas of oncology, including signaling pathways, tumor immunology, or small molecule/biologic therapeutics.
- Proficiency in modern drug discovery techniques, including high-throughput screening (HTS), structure-based drug design, and in vivo efficacy models.
- Proven ability to mentor and manage scientific teams.
- Excellent analytical, critical thinking, and problem-solving skills.
- Strong publication record and experience presenting at international scientific meetings.
- Exceptional communication and interpersonal skills, essential for remote collaboration.
- A genuine passion for advancing cancer treatment and improving patient outcomes.
This advertiser has chosen not to accept applicants from your region.
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Principal Drug Discovery Scientist - Oncology
G3 8DG Glasgow, Scotland
£95000 Annually
WhatJobs
Posted 11 days ago
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Job Description
Our client , a leading pharmaceutical innovator, is expanding its cutting-edge oncology research division and is seeking an exceptional Principal Drug Discovery Scientist. This role is crucial in driving the identification and validation of novel therapeutic targets and advancing pre-clinical drug candidates. This is a fully remote position, enabling you to contribute your expertise from anywhere in the UK.
As a Principal Drug Discovery Scientist, you will spearhead innovative research projects aimed at discovering and developing next-generation cancer therapies. You will utilize your deep scientific knowledge, extensive experience in molecular biology, biochemistry, and pharmacology, and a strong understanding of cancer biology to design and execute complex experiments. Your work will involve target identification and validation, hit-to-lead optimization, and guiding drug candidates through early development stages. This position offers a unique opportunity to work in a dynamic, collaborative, and remote-first environment.
Key Responsibilities:
As a Principal Drug Discovery Scientist, you will spearhead innovative research projects aimed at discovering and developing next-generation cancer therapies. You will utilize your deep scientific knowledge, extensive experience in molecular biology, biochemistry, and pharmacology, and a strong understanding of cancer biology to design and execute complex experiments. Your work will involve target identification and validation, hit-to-lead optimization, and guiding drug candidates through early development stages. This position offers a unique opportunity to work in a dynamic, collaborative, and remote-first environment.
Key Responsibilities:
- Lead and manage drug discovery programs in oncology, from target identification through to lead optimization.
- Design and implement rigorous experimental strategies to validate novel therapeutic targets and pathways.
- Develop and employ a range of in vitro and in vivo assays to assess drug efficacy, selectivity, and mechanism of action.
- Analyze complex biological data, interpret results, and make critical decisions to advance research programs.
- Collaborate closely with cross-functional teams, including medicinal chemists, DMPK scientists, and translational researchers.
- Supervise and mentor junior scientists, fostering a culture of scientific excellence and innovation.
- Prepare comprehensive research reports, presentations, and publications for internal and external audiences.
- Stay current with the latest scientific literature, emerging technologies, and competitive landscape in oncology drug discovery.
- Contribute to the strategic planning and direction of the oncology research portfolio.
- Ensure all research activities are conducted in compliance with ethical guidelines and company policies.
- PhD in Molecular Biology, Biochemistry, Pharmacology, Cancer Biology, or a closely related field.
- Minimum of 10 years of post-doctoral and industry experience in pharmaceutical or biotechnology drug discovery, with a strong focus on oncology.
- Proven track record of successfully delivering drug discovery projects, with contributions to candidates entering clinical development.
- Extensive hands-on experience with various molecular and cellular biology techniques, including but not limited to: target validation assays, cell-based assays, protein biochemistry, and signaling pathway analysis.
- Strong understanding of cancer biology, tumor microenvironment, and immunology.
- Experience with data analysis software and statistical methodologies.
- Excellent leadership, project management, and communication skills.
- Ability to thrive in a fast-paced, remote research environment and manage multiple projects simultaneously.
- Experience with antibody-drug conjugates (ADCs), small molecules, or immunotherapy is highly desirable.
- Must be eligible to work in the UK.
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7
Principal Drug Discovery Scientist (Oncology)
BN1 1AA East Sussex, South East
£75000 Annually
WhatJobs
Posted 11 days ago
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Job Description
Our client, a cutting-edge biopharmaceutical company, is actively seeking a highly motivated and experienced Principal Drug Discovery Scientist specializing in Oncology to join their innovative, fully remote research team. This critical role involves leading and executing ambitious drug discovery programs focused on developing novel therapeutics for cancer. You will be instrumental in identifying and validating new drug targets, designing and synthesizing small molecule inhibitors, and conducting preclinical studies to assess compound efficacy and safety. The ideal candidate will possess a Ph.D. in Medicinal Chemistry, Pharmacology, or a related life science discipline, coupled with a minimum of 8 years of progressive experience in oncology drug discovery within the pharmaceutical or biotech industry. Proven expertise in small molecule drug design, structure-activity relationship (SAR) analysis, and in vitro/in vivo pharmacology assays is essential. You should have a strong publication record in reputable scientific journals and a demonstrated ability to manage complex research projects independently. This role requires excellent leadership and mentorship skills, as you will guide and inspire junior scientists. Strong communication and collaboration skills are vital for working effectively within a distributed team and liaising with external partners. The position is entirely remote, offering the flexibility to work from anywhere in the UK. Responsibilities include designing and executing experimental strategies, interpreting complex data sets, contributing to patent filings, and presenting findings at international conferences. We are looking for a proactive, results-oriented scientist with a deep understanding of cancer biology and a passion for bringing life-changing medicines to patients. This is a unique opportunity to contribute significantly to groundbreaking research in a collaborative and supportive remote environment, impacting the future of cancer treatment from Brighton, East Sussex, UK , and beyond.
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Principal Drug Discovery Scientist - Oncology
SO14 0AA Southampton, South East
£90000 Annually
WhatJobs
Posted 15 days ago
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Job Description
Our client, a pioneering biopharmaceutical company at the forefront of innovative cancer therapeutics, is seeking a highly accomplished Principal Drug Discovery Scientist to join their world-class research team. This is a fully remote position, offering the flexibility to work from anywhere within the UK. You will be instrumental in driving our client's ambitious oncology pipeline, contributing to the discovery and development of groundbreaking medicines for patients in need.
As a Principal Drug Discovery Scientist, you will conceptualize, design, and execute innovative research strategies aimed at identifying novel therapeutic targets and developing first-in-class small molecule and biologics-based drugs for various cancer indications. Your deep scientific expertise will be leveraged to lead complex discovery projects from target validation through lead optimization. This role involves extensive collaboration with internal teams, including medicinal chemists, biologists, pharmacologists, and clinical development experts, as well as external academic collaborators and key opinion leaders.
Key responsibilities include designing and interpreting in vitro and in vivo experiments, managing external research collaborations, and critically evaluating emerging scientific literature to identify new research avenues. You will be responsible for presenting research findings at scientific conferences and publishing in high-impact peer-reviewed journals. The ability to mentor junior scientists, foster a culture of scientific rigor, and contribute to strategic decision-making regarding pipeline progression is essential. You will also play a key role in defining the scientific direction of the oncology discovery unit and identifying opportunities for strategic partnerships and acquisitions.
The ideal candidate will hold a PhD in Molecular Biology, Cancer Biology, Pharmacology, or a related discipline, with a strong publication record demonstrating significant contributions to the field of oncology drug discovery. A minimum of 10 years of post-doctoral and industry experience in drug discovery, with a proven track record of successfully advancing drug candidates through the preclinical stages, is required. Extensive experience in oncology target identification and validation, assay development, and small molecule or biologic drug discovery is mandatory. Exceptional understanding of cancer biology, tumor immunology, and resistance mechanisms is crucial. You must possess outstanding analytical and problem-solving skills, excellent written and verbal communication abilities, and a strong ability to lead and inspire research teams in a remote setting. Experience with data analysis software and bioinformatics tools is highly desirable.
As a Principal Drug Discovery Scientist, you will conceptualize, design, and execute innovative research strategies aimed at identifying novel therapeutic targets and developing first-in-class small molecule and biologics-based drugs for various cancer indications. Your deep scientific expertise will be leveraged to lead complex discovery projects from target validation through lead optimization. This role involves extensive collaboration with internal teams, including medicinal chemists, biologists, pharmacologists, and clinical development experts, as well as external academic collaborators and key opinion leaders.
Key responsibilities include designing and interpreting in vitro and in vivo experiments, managing external research collaborations, and critically evaluating emerging scientific literature to identify new research avenues. You will be responsible for presenting research findings at scientific conferences and publishing in high-impact peer-reviewed journals. The ability to mentor junior scientists, foster a culture of scientific rigor, and contribute to strategic decision-making regarding pipeline progression is essential. You will also play a key role in defining the scientific direction of the oncology discovery unit and identifying opportunities for strategic partnerships and acquisitions.
The ideal candidate will hold a PhD in Molecular Biology, Cancer Biology, Pharmacology, or a related discipline, with a strong publication record demonstrating significant contributions to the field of oncology drug discovery. A minimum of 10 years of post-doctoral and industry experience in drug discovery, with a proven track record of successfully advancing drug candidates through the preclinical stages, is required. Extensive experience in oncology target identification and validation, assay development, and small molecule or biologic drug discovery is mandatory. Exceptional understanding of cancer biology, tumor immunology, and resistance mechanisms is crucial. You must possess outstanding analytical and problem-solving skills, excellent written and verbal communication abilities, and a strong ability to lead and inspire research teams in a remote setting. Experience with data analysis software and bioinformatics tools is highly desirable.
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