376 Experimental Scientist jobs in the United Kingdom
Associate Experimental Scientist - NGS & Library Preparation (1 year Fixed Term)
Posted 1 day ago
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Job Description
CoSyne Therapeutics is a biotech innovator operating at the intersection of biology, AI and finance to unlock and rapidly advance overlooked treatments for patients with rare neurological disorders. Our multidisciplinary team spanning computational biology, AI, cellular science, and clinical expertise is united by a shared mission to bring hope to patients with unmet medical needs. Current programmes span neuro-oncology (low- and high-grade gliomas), genetic epilepsies, neuropathic pain, and demyelinating diseases.
The roleWe are seeking a motivated Associate Experimental Scientist with hands-on experience in next-generation sequencing (NGS) sample and library preparation. You will generate high-quality DNA and RNA libraries for WGS, bulk RNA-seq, and single-cell sequencing (with a strong preference for experience using the Parse Biosciences workflow). You will work closely with our Computational Biology and Experimental teams to deliver reproducible datasets, maintain rigorous QC, and support study designs that power our discovery engine. Cell culture and broader molecular biology skills are welcome but not essential for this role.
You will be based primarily at the Milner Therapeutics Institute (Cambridge Biomedical Campus), working in a collaborative, fast-moving environment with access to excellent facilities.
Requirements
NGS sample and library preparation- Extract, purify and quantify DNA and RNA from diverse sample types (cells, tissues, organoids) following SOPs.
- Prepare sequencing libraries for WGS, bulk RNA-seq and single-cell assays; strong preference for experience with Parse Biosciences single-cell chemistry.
- Perform fragmentation, end-repair/A-tailing, adaptor ligation, barcoding/indexing, PCR amplification and cleanup (SPRI bead-based).
- Optimise protocols for yield and quality; implement positive/negative controls and spike-ins as appropriate.
- Carry out stringent QC using Qubit/UV spectrophotometry, TapeStation (size distributions, RIN/DIN), and qPCR-based quantification.
- Calculate molarity, normalise and pool libraries; prepare final pools for sequencing.
- Coordinate submissions to core facilities and vendors; ensure accurate metadata capture and chain-of-custody.
- Record all procedures, parameters and results in the ELN/LIMS (e.g., Benchling) with version-controlled SOP adherence.
- Generate concise run reports and QC summaries for cross-functional reviews; hand off data and metadata cleanly to Computational Biology for downstream analysis.
- Maintain an organised NGS lab area; manage inventories of kits, enzymes and consumables; track lot numbers and expiry.
- Support ordering and invoice processing; contribute to equipment maintenance and calibrations.
- Uphold biosafety and contamination-control best practices (e.g., unidirectional workflows, UV decontamination).
- Partner with Experimental and Computational colleagues on experimental design, sample randomisation and batch-effect mitigation.
- Pilot new kits and chemistries; contribute to SOP creation/refinement and troubleshooting.
- Optional: support basic molecular biology (cloning, qPCR).
- BSc or MSc in Molecular Biology, Genomics, Biotechnology or related discipline or equivalent industry experience.
- Proven hands-on experience preparing NGS libraries (WGS, bulk RNA-seq, single-cell); strong preference for Parse Biosciences single-cell library prep.
- Proficiency with QC instrumentation (Qubit/NanoDrop, TapeStation) and qPCR-based quantification; confident with molarity calculations and pooling strategies.
- Meticulous record-keeping, excellent organisational skills, and high standards for data integrity and reproducibility.
- Thrive in a fast-paced environment; proactive, curious, and solutions-oriented.
- Collaborative mindset; value diverse viewpoints; be kind.
- Right to work in the UK.
- Familiarity with Illumina-ecosystem chemistries and indexing strategies; awareness of UMIs and index hopping considerations.
- Experience interfacing with sequencing cores and managing sample manifests/metadata.
- Exposure to automation (e.g., Opentrons, Agilent Bravo) and liquid-handling best practices.
- Experience with ELN/LIMS (e.g., Benchling) and basic scripting (R/Python) for QC plots highly desirable.
- Basic cell culture and general molecular biology skills.
Benefits
Benefits and working arrangements- Private health insurance and company life insurance policy.
- Enhanced holiday package (25 days plus Christmas/New Year closure).
- All the perks of a start-up: team dinners/socials, flexible working, and a dynamic environment.
- Offices in Soho, London; laboratory operations at the Milner Therapeutics Institute in Cambridge.
- This role is primarily onsite in Cambridge and offered on a 12-month fixed-term contract.
We are an inclusive workplace and Equal Opportunity Employer; all qualified applicants will receive consideration for employment regardless of age, disability, sex, race, religion or belief, gender reassignment, marriage/civil partnership, pregnancy/maternity, or sexual orientation.
Right to workApplicants must already have the right to work in the UK; we are unable to sponsor visas for this position. All applicants will be required to provide evidence of their right to work in the UK as part of the recruitment process.
Data privacyBy applying you understand that, even if unsuccessful, the personal documentation and information you supply will be held in our recruitment system for a 6-month period, after which it will be permanently deleted.
Senior Scientist - Research & Development
Posted 12 days ago
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Job Description
Leica Biosystems is proud to work alongside a community of six fellow Diagnostics Companies at Danaher. Together, we're working at the pace of change to improve patient lives with diagnostic tools that address the world's biggest health challenges.
The Senior Research & Development Scientist - Advanced Staining Reagents is a key technical contributor to the development of immunochemistry technology and advanced staining reagent products. This position forms part of LBS initiative as a leading-edge cancer diagnostics partner with a vision to advance cancer diagnostics and improve lives.
This position is part of the Research and Development (R&D) team located in Newcastle and will be an on-site, position. You will be a part of the Advanced Staining Reagents (ASR) R&D team and report to the R&D Manager. In this role you are a resource for all New Product Development projects and Compliance work performed in the R&D team.
If you thrive in an innovative research and development environment and want to be part of a world-class R&D organization, read on.
In this role, you will have the opportunity to:
+ Lead projects and gain insight from other department SMEs.
+ Become part of a team responsible for the delivery of cutting edge new diagnostic products.
+ Become an expert on designing, performing and interpreting experiments on the automated staining instrumentation.
+ Be part of a wider R&D organisation, gaining exposure to a variety of different project types.
+ Learn and implement the process of developing products within a regulatory environment.
The essential requirements of the job include:
+ Significant prior lab experience within a regulated environment and understanding of IHC and molecular biology techniques (e.g.FISH).
+ Possess a Degree in a scientific subject
+ Have knowledge of H&S and how this applies to Laboratory environments
+ Have experience of project delivery in a high-pressure environment
It would be a plus if you also possess previous experience in:
+ In-depth experience of Molecular Biology
+ Experience of working within a regulated environment
+ A higher degree
Join our winning team today. Together, we'll accelerate the real-life impact of tomorrow's science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.
For more information, visit .
At Danaher, we value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve. Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes.
Join our winning team today. Together, we'll accelerate the real-life impact of tomorrow's science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.
For more information, visit .
Research & Development Engineer
Posted 4 days ago
Job Viewed
Job Description
We’re looking for a talented R&D Engineer to join a forward-thinking engineering team. You’ll take products from concept through design, prototyping, testing, and into production—using customer feedback and performance data to shape results.
What You’ll Do:
- p>Develop and improve products from concept to launch
-
Analyse market and user feedback for design improvements
-
Use data to solve engineering challenges and measure results
-
Manage bespoke projects from design to delivery
-
Provide technical support for products in the field
-
Keep up to date with emerging tech and market trends
What You’ll Bring:
- < i>
-
Extensive product development or engineering support experience
-
3D CAD skills (Autodesk Inventor ideal)
-
Confident with technical documentation and MS Office (ERP/MRP a bonus)
-
Proactive problem-solver with a drive for improvement
-
Excellent communicator and team player
Degree in Mechanical Engineering or similar
Must have UK work eligibility and a full UK driving licence.
Apply now and turn ideas into real-world solutions.
Research & Development Engineer
Posted 11 days ago
Job Viewed
Job Description
White Label is exclusively representing an engineering and manufacturing business in Bradford that requires a Design & Development Engineer to join their team.
The role will be varied and involve design and testing of products so this role would suit someone who enjoys being hands-on with the full design and development process.
Package/Benefits
- A salary of up to £35,000 - £40,000 depending on experience. li>Working hours – 36.25 per week. 08.30 am to 4.30 pm Monday to Thursday and 8.30 am to 3.15 pm Friday.
- Pension - Employee contribution 5%, Employer contribution 3%
- Other benefits - Life assurance of 4x salary after 3 months of continuous service.
Responsibilities of the Design & Development Engineer
- 3D Solid modelling using SolidWorks 2025
- FEA of 3D Models using Solidworks.
- Design of castings, pressings & turned/cold formed assemblies.
- Design calculations using Excel spreadsheets incorporating load distribution and stress calculations.
- Use of industry standards; Eurocode 3, AISC /ASTM etc
- Production of manufacturing drawings using Solidworks.
- Produce product specifications & technical reports.
- Communicate with customers, approval bodies and independent test laboratories.
- To assist in product testing using 50kN/1000 kN/2000kN Test machine.
- Prepare test reports including graphs and test data.
- Formulate answers to technical questions from customers and assist the Technical Support and Quality departments.
- Production of illustrations and technical data for marketing.
Experience required of the Design & Development Engineer
- Educated to degree/HNC level in Mechanical Engineering or similar.
- Solidworks experience is essential.
- 2 years minimum experience in a mechanical engineering, structural or construction environment.
This vacancy is being managed by Paul Smith. Apply now for immediate consideration.
Research & Development Engineer
Posted 8 days ago
Job Viewed
Job Description
We’re looking for a talented R&D Engineer to join a forward-thinking engineering team. You’ll take products from concept through design, prototyping, testing, and into production—using customer feedback and performance data to shape results.
What You’ll Do:
- p>Develop and improve products from concept to launch
-
Analyse market and user feedback for design improvements
-
Use data to solve engineering challenges and measure results
-
Manage bespoke projects from design to delivery
-
Provide technical support for products in the field
-
Keep up to date with emerging tech and market trends
What You’ll Bring:
- < i>
-
Extensive product development or engineering support experience
-
3D CAD skills (Autodesk Inventor ideal)
-
Confident with technical documentation and MS Office (ERP/MRP a bonus)
-
Proactive problem-solver with a drive for improvement
-
Excellent communicator and team player
Degree in Mechanical Engineering or similar
Must have UK work eligibility and a full UK driving licence.
Apply now and turn ideas into real-world solutions.
Research & Development Engineer
Posted 14 days ago
Job Viewed
Job Description
White Label is exclusively representing an engineering and manufacturing business in Bradford that requires a Design & Development Engineer to join their team.
The role will be varied and involve design and testing of products so this role would suit someone who enjoys being hands-on with the full design and development process.
Package/Benefits
- A salary of up to £35,000 - £40,000 depending on experience. li>Working hours – 36.25 per week. 08.30 am to 4.30 pm Monday to Thursday and 8.30 am to 3.15 pm Friday.
- Pension - Employee contribution 5%, Employer contribution 3%
- Other benefits - Life assurance of 4x salary after 3 months of continuous service.
Responsibilities of the Design & Development Engineer
- 3D Solid modelling using SolidWorks 2025
- FEA of 3D Models using Solidworks.
- Design of castings, pressings & turned/cold formed assemblies.
- Design calculations using Excel spreadsheets incorporating load distribution and stress calculations.
- Use of industry standards; Eurocode 3, AISC /ASTM etc
- Production of manufacturing drawings using Solidworks.
- Produce product specifications & technical reports.
- Communicate with customers, approval bodies and independent test laboratories.
- To assist in product testing using 50kN/1000 kN/2000kN Test machine.
- Prepare test reports including graphs and test data.
- Formulate answers to technical questions from customers and assist the Technical Support and Quality departments.
- Production of illustrations and technical data for marketing.
Experience required of the Design & Development Engineer
- Educated to degree/HNC level in Mechanical Engineering or similar.
- Solidworks experience is essential.
- 2 years minimum experience in a mechanical engineering, structural or construction environment.
This vacancy is being managed by Paul Smith. Apply now for immediate consideration.
Research Development Project Engineer
Posted today
Job Viewed
Job Description
R&D Project Engineer – Bristol – Aerospace - £48,000 to £55,000
Melbreck Technical are seeking an experienced Project Engineer to join our clients cutting-edge Research & Development team, where you will be leading projects that have a significant commercial and technical importance. They are a large global aerospace company, who are renowned for their market leading expertise in aircraft systems.
This is a full-time position is based in their Bristol, UK office, where you will join a small team of engineers working on new technology developments, managed locally by the senior leadership team. Your role will be crucial in the business as you will be directly responsible for leading and delivering on key research and development projects.
You will play a key part in the development of novel technologies and system solutions, commencing from concept to prototype, as well as attend and leading regular team meetings to review progress against project goals and budgets. You will also work closely with US team members as well as suppliers and customers across the world.
R&D Project Engineer - Role description:
Plan, lead, and deliver on key research and development projects.
Developing new technology strategies to support business needs.
Liaise with both internal and external stakeholders, to ensure that the direction of projects and products is communicated in a timely manner.
Take a technical stance on projects and products to ensure feasibility and continuity.
Supporting the wider business in technological advances.
Support the wider leadership team in helping to mentor and develop more junior engineers who are earlier on in their career.
R&D Project Engineer - Required background and experience:
Degree in Aerospace Engineering is of preference, but Mechanical Engineering, or other relevant technical or scientific subject would be considered.
Understanding and experience of Cryogenics would be a significant advantage.
Previous experience of taking a technology from concept to prototype e.g. Technology Readiness Level 2 through 6.
Between 5 and 10 years’ experience in aerospace is preferred, but experience in cryogenic systems would also be considered.
Ability to interpret complex engineering drawings and technical design information.
Knowledge and understanding of validation and verification.
Demonstrated ability to solve complex problems and conduct investigations.
Proficiency in technical report writing and presentations.
Desirable experience:
Previous experience with sensor design and sensor networks
Previous experience with aircraft fuel systems
Knowledge of specific Aerospace standards, ARP4754, ARP4761 and ARINC611
Experience of a wide range of testing, ranging from bench and lab tests, through to large scale ground and flight testing.
R&D Project Engineer - Required characteristics:
A desire to learn new skills, to grow, or to become a Chartered Engineer
Ability to work within a geographically diverse team using remote tools (e.g. video conferencing)
Ability to travel within the UK, to the US, and to Europe to support the projects, customers, and suppliers
R&D Project Engineer – Hours and Benefits:
37.5 hours per week – Monday to Friday
4 days in the office, 1 day working from home
Up to 10% bonus
Up to 15% pension
Excellent employee welfare schemes and programs
If you are looking to work for a business that truly values your efforts and where you can be a part of the strategic success of a global outfit, then click APPLY NOW
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Senior Research Scientist - Biopharmaceutical Development
Posted today
Job Viewed
Job Description
Key Responsibilities:
- Design and conduct advanced research experiments in biopharmaceutical development.
- Develop, validate, and implement novel biological assays and methodologies.
- Analyze complex experimental data using statistical software and provide insightful interpretations.
- Contribute to the preclinical evaluation of therapeutic candidates.
- Troubleshoot technical challenges and propose innovative solutions.
- Collaborate with internal teams on process development and optimisation.
- Prepare scientific reports, manuscripts for publication, and contribute to regulatory filings.
- Stay abreast of the latest scientific literature and technological advancements.
- Mentor junior scientists and provide technical guidance.
- Ensure strict adherence to laboratory safety protocols and GLP standards.
- Ph.D. in Biochemistry, Molecular Biology, Pharmacology, or related field.
- 5+ years of post-doctoral or industry experience in biopharmaceutical R&D.
- Expertise in areas such as antibody engineering, protein expression, or cell-based assays.
- Proven ability to design, execute, and analyze complex experiments.
- Strong publication record in reputable scientific journals.
- Experience with statistical analysis and data interpretation software.
- Excellent critical thinking, problem-solving, and communication skills.
- Ability to work effectively in a team-oriented research environment.
Senior Research Scientist - Pharmaceutical Development
Posted today
Job Viewed
Job Description
The Senior Research Scientist will lead and conduct research projects focused on the discovery and optimization of new drug candidates. You will be responsible for designing and executing experiments, analyzing complex biological and chemical data, and contributing to the development of pre-clinical and clinical strategies. This role requires a strong background in medicinal chemistry, pharmacology, or a related life science discipline, with a proven ability to conduct independent research and contribute to team-based projects.
Key responsibilities include designing and synthesizing novel chemical entities, evaluating their biological activity in vitro and in vivo, and characterizing their pharmacokinetic and pharmacodynamic properties. You will also be involved in literature reviews, identifying new research opportunities, and presenting findings at internal meetings and scientific conferences. The ideal candidate will have a PhD in a relevant scientific discipline, extensive hands-on laboratory experience, and a deep understanding of drug discovery processes. Proficiency in analytical techniques such as HPLC, LC-MS, NMR, and bioassays is essential. Excellent scientific judgment, strong problem-solving skills, and the ability to manage multiple research activities simultaneously are critical. Experience with specific therapeutic areas or target classes would be advantageous.
We are seeking a scientifically rigorous and results-oriented individual with a passion for pharmaceutical research and a commitment to improving patient outcomes. The ability to work collaboratively in a multidisciplinary team and to mentor junior scientists is highly valued. You will be expected to maintain detailed laboratory notebooks and contribute to the writing of research reports and publications.
Responsibilities:
- Lead and conduct research projects in drug discovery and development.
- Design, synthesize, and characterize novel chemical compounds.
- Evaluate the biological activity of drug candidates using in vitro and in vivo models.
- Perform pharmacokinetic and pharmacodynamic studies.
- Analyze complex scientific data and interpret experimental results.
- Contribute to the development of pre-clinical and clinical research strategies.
- Stay current with scientific literature and emerging trends in pharmaceutical research.
- Present research findings at internal meetings and scientific conferences.
- Collaborate effectively with cross-functional teams (e.g., biology, DMPK, CMC).
- Mentor and guide junior research scientists.
- PhD in Medicinal Chemistry, Pharmacology, Biochemistry, or a related life science field.
- Minimum of 5 years of post-doctoral or industry research experience in drug discovery.
- Proven track record of contributing to novel drug candidate identification and optimization.
- Expertise in synthetic organic chemistry and/or various bioassay techniques.
- Proficiency with analytical instrumentation (HPLC, LC-MS, NMR).
- Strong understanding of drug development processes and regulatory requirements.
- Excellent analytical, problem-solving, and critical thinking skills.
- Strong written and verbal communication skills.
Pharmaceutical Research Scientist - Formulation Development
Posted today
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Job Description
Key Responsibilities:
- Design, develop, and optimize pharmaceutical formulations for various dosage forms (e.g., oral solids, injectables, topical).
- Conduct pre-formulation studies to understand drug substance characteristics.
- Perform formulation experiments, analyze results, and document findings meticulously.
- Utilize a range of analytical techniques (e.g., HPLC, dissolution testing, particle size analysis) to characterize formulations.
- Collaborate with analytical development and quality control teams to ensure successful transfer of formulations to manufacturing.
- Prepare technical reports, protocols, and regulatory documentation.
- Stay current with scientific literature, industry trends, and regulatory guidelines in formulation development.
- Participate in project team meetings and contribute scientific expertise.
- Troubleshoot formulation and process-related issues.
- Assist in the scale-up and technology transfer of formulations to pilot and commercial manufacturing.
- Contribute to the selection of appropriate excipients and manufacturing processes.
- Maintain a safe and organized laboratory environment.
The ideal candidate will possess:
- A Bachelor's or Master's degree in Pharmacy, Pharmaceutical Sciences, Chemistry, or a related discipline. A PhD is highly desirable.
- Proven experience (3+ years) in pharmaceutical formulation development within an R&D setting.
- Hands-on experience with various dosage forms and formulation techniques.
- Proficiency in relevant analytical instrumentation and techniques.
- Strong understanding of pharmaceutics, drug delivery systems, and CMC regulations.
- Excellent data analysis, problem-solving, and critical thinking skills.
- Effective written and verbal communication skills.
- Ability to work independently and as part of a collaborative research team.
- Meticulous attention to detail and a commitment to scientific rigor.
- Experience with Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) is beneficial.
This is a superb opportunity to contribute to cutting-edge pharmaceutical research and development in Southampton, Hampshire, UK . If you are a dedicated scientist eager to make a tangible impact on human health, we encourage you to apply.