21 Gsk jobs in the United Kingdom

Our client, a leading pharmaceutical company, is seeking an accomplished Senior Formulation Scientist to join their cutting-edge research and development department based in Leicester, Leicestershire . This is a crucial laboratory-based role focused on developing innovative drug formulations that enhance therapeutic efficacy and patient compliance. You will be instrumental in the entire lifecycle of formulation development, from early-stage concept to late-stage clinical support.

Responsibilities:

• Design and execute experiments to develop novel drug formulations (e.g., oral solid dosage forms, injectables, topical preparations) for small molecules and biologics.
• Investigate and optimize pre-formulation properties, including solubility, stability, and compatibility studies.
• Develop and validate analytical methods for characterizing drug substances and drug products.
• Conduct stability studies according to ICH guidelines and interpret results to establish shelf-life.
• Prepare formulation development reports, present findings at internal meetings, and contribute to regulatory submissions.
• Collaborate with cross-functional teams, including analytical development, process development, regulatory affairs, and manufacturing.
• Troubleshoot formulation-related issues encountered during development and scale-up.
• Stay abreast of scientific literature, emerging technologies, and industry best practices in pharmaceutical formulation.
• Supervise and mentor junior scientists and technicians within the formulation team.
• Ensure all laboratory activities are conducted in compliance with GMP and safety regulations.
• Participate in technology transfer activities to manufacturing sites.

Qualifications:

• Ph.D. or Master's degree in Pharmaceutics, Chemistry, Pharmaceutical Sciences, or a related discipline.
• Minimum of 5-7 years of progressive experience in pharmaceutical formulation development.
• Hands-on experience with a variety of dosage forms and formulation techniques.
• Strong understanding of physical chemistry, materials science, and drug delivery principles.
• Proficiency in analytical techniques such as HPLC, DSC, TGA, XRPD, and microscopy.
• Experience with formulation development software and statistical analysis tools.
• Excellent problem-solving, analytical, and critical thinking skills.
• Strong written and verbal communication skills, with the ability to effectively present technical information.
• Ability to work effectively in a fast-paced, collaborative laboratory environment.
• Knowledge of regulatory requirements (e.g., FDA, EMA) related to drug development and manufacturing.

This is an exciting opportunity for a seasoned formulation scientist to contribute to the development of life-changing medicines within a renowned pharmaceutical organisation located in Leicester, Leicestershire .

Our client, a pioneering biopharmaceutical company based in the vibrant scientific hub of **Cambridge**, is seeking an exceptional Principal Formulation Scientist to lead innovative drug development initiatives. This is a fully remote, high-impact role offering the chance to work at the forefront of pharmaceutical research and development from your preferred location. You will be responsible for the design, development, and optimization of novel drug delivery systems and formulations, driving projects from early-stage concept through to preclinical and clinical evaluation. This position requires deep scientific expertise, a rigorous experimental approach, and a strategic vision for advancing therapeutic solutions.

Responsibilities:

• Lead the formulation development of complex pharmaceutical products, including small molecules, biologics, and advanced therapies.
• Design and execute experimental strategies to optimize drug solubility, stability, bioavailability, and release profiles.
• Utilize a range of characterization techniques (e.g., HPLC, DLS, DSC, SEM) to assess formulation performance.
• Develop and validate analytical methods for formulation analysis.
• Manage and mentor a team of formulation scientists and technicians.
• Collaborate closely with cross-functional teams including medicinal chemistry, process development, DMPK, and clinical operations.
• Interpret experimental data, troubleshoot formulation challenges, and propose innovative solutions.
• Prepare comprehensive technical reports, protocols, and regulatory submission documents.
• Stay abreast of scientific literature, emerging technologies, and industry trends in formulation science.
• Contribute to the strategic direction of the R&D pipeline and intellectual property development.

Qualifications:

• Ph.D. in Pharmaceutical Sciences, Chemical Engineering, Materials Science, or a related discipline.
• Minimum of 8 years of progressive experience in pharmaceutical formulation development within the biotech or pharmaceutical industry.
• Demonstrated expertise in a variety of dosage forms (e.g., oral, injectable, topical) and delivery technologies.
• In-depth understanding of drug substance properties and their impact on formulation.
• Proficiency with common laboratory equipment and analytical instrumentation used in formulation science.
• Strong project management skills and experience leading R&D projects.
• Excellent written and verbal communication skills, with a proven ability to present complex scientific information.
• Experience with preclinical and/or early-phase clinical studies is highly advantageous.
• Ability to work independently and as part of a distributed, global team.
• A strong publication record or patent contributions is a plus.

This is a unique opportunity to join a dynamic research organization and contribute significantly to the development of life-changing medicines. If you are a visionary scientist passionate about pushing the boundaries of pharmaceutical formulation, we invite you to apply for this exciting remote role.

Our client is seeking an accomplished Senior Formulation Scientist to join their innovative pharmaceutical research and development team based in **Liverpool, Merseyside, UK**. This critical role involves leading the design, development, and optimization of novel drug formulations, from early-stage research through to clinical trial supply. You will be instrumental in translating scientific concepts into viable drug products, addressing complex formulation challenges, and ensuring regulatory compliance. The ideal candidate possesses extensive experience in pharmaceutical formulation, a strong understanding of drug delivery systems, and a proven ability to lead projects and mentor junior scientists.

Key Responsibilities:

• Lead the formulation development of new drug candidates, including small molecules and biologics.
• Design and execute experiments to characterize drug substances and excipients.
• Develop and optimize dosage forms (e.g., oral solids, injectables, topical).
• Investigate and resolve formulation-related issues encountered during development.
• Develop and validate analytical methods for formulation characterization.
• Conduct stability studies and interpret results to define shelf-life.
• Prepare comprehensive formulation development reports and regulatory submission documents.
• Collaborate closely with analytical development, DMPK, and manufacturing teams.
• Stay current with scientific literature, industry trends, and regulatory guidelines.
• Mentor and guide junior formulation scientists, fostering a culture of scientific excellence.

Qualifications:

• A Ph.D. or Master's degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related field.
• A minimum of 5-7 years of experience in pharmaceutical formulation development.
• In-depth knowledge of various dosage forms, drug delivery technologies, and excipient functionalities.
• Experience with pre-formulation studies, solubility enhancement techniques, and analytical characterization.
• Proficiency in experimental design and statistical analysis.
• Strong understanding of regulatory requirements (e.g., ICH guidelines).
• Excellent problem-solving, organizational, and project management skills.
• Effective written and verbal communication abilities, with experience presenting to cross-functional teams and stakeholders.
• Demonstrated leadership potential and experience mentoring team members.

This hybrid role offers a balanced approach to work, combining essential in-lab activities with the flexibility to work remotely. You will be part of a dynamic and collaborative environment at the forefront of pharmaceutical innovation, contributing directly to the development of life-changing medicines. Our client offers a competitive compensation package, excellent benefits, and significant opportunities for professional growth and career advancement within the pharmaceutical industry.

Our client is seeking an experienced and visionary Lead Formulation Scientist to drive innovation within their Pharmaceutical division in **Liverpool, Merseyside, UK**. This hybrid role combines essential on-site laboratory work with flexible remote responsibilities. You will be instrumental in the design, development, and optimization of novel drug delivery systems and formulations, from early-stage research through to clinical development and commercialization. This position requires a deep understanding of pharmaceutical sciences, material science, and drug product manufacturing processes. You will lead a team of scientists, manage projects, and collaborate with cross-functional teams to advance pipeline assets.

Key Responsibilities:

• Lead the formulation development of new chemical entities and complex drug products (e.g., injectables, oral solids, biologics).
• Design and execute experimental studies to evaluate drug solubility, stability, bioavailability, and manufacturability.
• Develop and optimize formulation strategies to achieve desired therapeutic profiles and patient compliance.
• Characterize drug product performance using a range of analytical techniques.
• Oversee technology transfer activities to manufacturing sites and support process validation.
• Manage project timelines, resources, and budgets, ensuring timely delivery of milestones.
• Mentor and guide junior formulation scientists, fostering a culture of scientific excellence and innovation.
• Collaborate closely with preclinical, clinical, regulatory, and manufacturing teams.
• Author and review technical reports, protocols, and regulatory submission documents.
• Stay current with industry trends, new technologies, and regulatory guidelines in pharmaceutical formulation.

The ideal candidate will possess a Ph.D. in Pharmaceutical Sciences, Chemical Engineering, Materials Science, or a related discipline, with a minimum of 7 years of relevant industry experience. Demonstrated success in leading formulation development projects and a strong understanding of GMP principles are essential. Expertise in various dosage forms, particularly parenteral and oral drug delivery, is required. Excellent problem-solving, critical thinking, and communication skills are crucial for success in this role. Experience with statistical analysis and design of experiments (DoE) is highly desirable. Join a leading pharmaceutical company in **Liverpool, Merseyside, UK**, and make a significant impact on the future of medicine.

Our client, a cutting-edge pharmaceutical research and development company, is seeking a highly experienced Principal Formulation Scientist to join their fully remote R&D team. This senior role is instrumental in driving the innovation and development of novel drug delivery systems and pharmaceutical formulations. You will lead the scientific direction for formulation development projects, from early-stage concept through to pre-clinical and clinical readiness, contributing significantly to the company's pipeline.

Key Responsibilities:

• Lead the design, development, and optimization of complex pharmaceutical formulations (e.g., oral solid dosage, parenteral, topical) for new chemical entities and existing drug products.
• Develop and execute comprehensive experimental plans to assess formulation performance, stability, and manufacturability.
• Provide strategic scientific leadership and technical guidance to a team of formulation scientists and technicians.
• Troubleshoot formulation challenges and identify innovative solutions to overcome development hurdles.
• Conduct in-depth literature reviews and stay current with emerging technologies and scientific advancements in pharmaceutics and drug delivery.
• Prepare and review detailed technical reports, study protocols, and regulatory submission documents (e.g., IND, NDA).
• Collaborate effectively with cross-functional teams, including analytical development, process chemistry, DMPK, and clinical operations, in a remote setting.
• Present scientific findings and project updates to internal stakeholders and external partners.
• Contribute to the intellectual property strategy through patent filings and publications.
• Ensure all activities are conducted in compliance with GMP, GLP, and other relevant regulatory guidelines.

The ideal candidate will possess a Ph.D. or Master's degree in Pharmaceutics, Pharmaceutical Sciences, Chemistry, or a related discipline, with a minimum of 8 years of progressive experience in pharmaceutical formulation development. A deep understanding of formulation science principles, excipient functionality, and various drug delivery technologies is crucial. Proven experience in leading complex R&D projects and mentoring scientific staff is required. Excellent communication, problem-solving, and organizational skills are essential for success in this remote-first environment. Proficiency in relevant laboratory techniques and analytical methods is expected. This position, though located conceptually near Sunderland, Tyne and Wear, UK , operates entirely remotely.

Our client, a pioneering pharmaceutical company at the forefront of medical innovation, is seeking a highly skilled Senior Formulation Scientist to join their fully remote drug development team. This role is integral to the design, development, and optimisation of novel drug delivery systems and pharmaceutical formulations. You will work independently and collaboratively with a distributed team of experts to advance candidate drugs from pre-clinical stages through to clinical trials and beyond.

The Senior Formulation Scientist will be responsible for developing robust and scalable formulations for various routes of administration, including oral, parenteral, and topical delivery. This involves selecting appropriate excipients, conducting pre-formulation studies, and optimising formulation parameters to achieve desired physicochemical properties, bioavailability, and stability. You will design and execute experimental plans, analyse data using statistical methods, and interpret results to make informed decisions. A key aspect of this role is troubleshooting formulation challenges and proposing innovative solutions. The Senior Formulation Scientist will prepare detailed documentation, including formulation development reports, protocols, and relevant sections for regulatory submissions (e.g., IND, NDA). You will stay abreast of the latest advancements in formulation science, drug delivery technologies, and regulatory guidelines. As a remote position, excellent self-management, communication, and collaboration skills are essential. You will be expected to actively participate in virtual team meetings, present findings effectively, and contribute to a dynamic, science-driven culture. This role requires a deep understanding of pharmaceutics, material science, and analytical techniques commonly used in drug development. The ability to work autonomously while contributing to team goals is critical for success.

We are at the forefront of innovation and seeking a distinguished Principal Research Scientist to lead our initiatives in applying Artificial Intelligence (AI) and Machine Learning (ML) to drug development. This fully remote role is a unique opportunity to shape the future of pharmaceutical research by integrating cutting-edge computational approaches with biological and chemical data. You will guide research strategies, mentor a team of scientists, and collaborate with industry leaders to accelerate the discovery and development of life-saving medicines. As a remote-first organization, we foster an environment of innovation, collaboration, and impact.

Responsibilities:

• Lead the design and implementation of AI/ML models and algorithms for various stages of drug discovery and development (e.g., target identification, hit identification, lead optimization, clinical trial design).
• Develop and execute research roadmaps, setting ambitious yet achievable scientific goals.
• Analyze large, complex biological, chemical, and clinical datasets to extract meaningful insights.
• Collaborate with domain experts (biologists, chemists, clinicians) to translate complex problems into AI/ML solutions.
• Mentor and guide a team of data scientists and research scientists, fostering their technical and scientific growth.
• Stay abreast of the latest advancements in AI/ML, computational biology, cheminformatics, and drug discovery.
• Develop and present research findings to internal stakeholders, leadership, and at external scientific forums.
• Contribute to the intellectual property strategy through patent applications and publications.
• Ensure the ethical and responsible application of AI/ML in drug development.
• Evaluate and integrate new technologies and tools to enhance research capabilities.
• Manage research projects, timelines, and resources effectively in a remote setting.

Qualifications:

• Ph.D. in Computer Science, Data Science, Computational Biology, Cheminformatics, Bioinformatics, or a related quantitative field.
• Minimum of 8+ years of relevant research experience in AI/ML, with a significant focus on pharmaceutical or life sciences applications.
• Demonstrated expertise in developing and deploying machine learning models for predictive tasks in drug discovery (e.g., QSAR, molecular property prediction, generative models).
• Proficiency in programming languages such as Python and R, and familiarity with AI/ML frameworks (e.g., TensorFlow, PyTorch).
• Experience working with large-scale biological, chemical, and clinical datasets.
• Strong understanding of drug discovery processes and relevant scientific disciplines.
• Excellent leadership, communication, and interpersonal skills, with the ability to influence and collaborate across diverse teams.
• Proven track record of scientific innovation, publications, and/or patents.
• Ability to work autonomously and lead research efforts in a remote environment.

This impactful, fully remote position is associated with our hub in **Birmingham, West Midlands, UK**, offering flexibility and global reach.

**Work Schedule**
Standard (Mon-Fri)
**Environmental Conditions**
Office
**Job Description**
At Thermo Fisher Scientific, you'll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on - now and in the future.
**The PPD FSP Solution:**
PPD's Functional Service Provider division partner with and serve as an extension of our PPD team, supporting our customers key functions. We cover customer needs on every level, allowing them to do more with less, with an uncompromising commitment to quality. We deploy the same top-tier talent in ALL engagement models. Exceptionally trained, rigorously supported and technologically empowered to help customers manage capacity and set programs up for success.
Joining within our PPD FSP functional area, allows you to join the renowned PPD CRO and still gain invaluable client dedicated experience.
_Our client, a global mid-sized biotech company, focuses on developing innovative treatments for patients with autoimmune diseases. This fast-growing, international organization has a strong scientific foundation. If you're looking for a place where your work, in partnership with others, can have real impact-and where you're encouraged challenge yourself and contribute to breakthrough solutions , the_ **_A_** **_ssociate Director, Drug Development_** _role could be a great fit._
**Discover Impactful Work:**
The Associate Director within Drug Development will oversee high-level plans and progress for asset development, from pre-clinical stages to commercial launch. This role involves close collaboration with various stakeholders to ensure timely availability of documents and alignment with corporate strategy. Act as primary point of contact when concerning integrated cross-functional project planning and status. They closely collaborate with stakeholders who own, contribute to, and/or manage the project and the impact of decisions and changing circumstances. This to drive timely availability of documents as planned.
**A day in the Life:**
_Project Lead responsibilities:_
+ Serves as the primary contact between the sponsor and the organization at the project level.
+ On projects where the scope requires, ensures clear delineation in responsibilities and communication pathways for secondary project leads (such as lead in a specific region, lead for a specific vendor(s) or subset of delivery).
+ Drives and owns the overall delivery of the cross-functional project (time, cost, quality).
+ Ensures financial stewardship at a project level by demonstrating an intimate understanding of the contract, resource alignment to budget, management of Out of Scope activity, drive the Con Mod process/negotiations and team execution to timelines.
+ Establishes, communicates and manages customer expectations to achieve optimal delivery during the project.
+ Drives Risk Identification and Issue Resolution at project level (RBQM/RESOLVE).
+ Ensures project team compliance with organization policies, SOPs, ICH- GCP, regulatory and project specific requirements
_Oversight Director responsibilities:_
+ Accountable for strategic indication or client-specific portfolio management within a Therapeutic Unit.
+ Expertly navigates the need to dive in/dive out of situations while ensuring the Project Lead remains empowered .
+ Provokes critical thinking in Project Lead related to execution of delivery, financial negotiations and prioritization.
+ Provides insight into proposal strategy in prep for bid defense.
+ Works with Therapeutic Unit Head in development of business growth strategies.
+ Maintains awareness and engages as appropriate in the Con Mod process.
+ Communicates with People Manager(s) to support the development of the employee providing expertise and perspective related to client needs, indication and therapeutic knowledge.
_People Manager responsibilities:_
+ Accountable for the career development and performance management of a group of project delivery direct reports in line with The Core People Manager Expectations at the organization.
+ Partners with project team leadership and key stakeholders (i.e OD, SLT, BPL, DevOps, functional leadership) to ensure areas of development, training needs and coaching are aligned through routine and active engagement.
+ Provides coaching, soft skill and technical skill development to grow our Project Delivery talent.
+ Provides support/direction to direct report(s) with regards to knowledge of organization systems, processes and tools within Project Delivery.
+ Liaises with Resourcing Leads, TU Leadership and other key stakeholders to advocate for direct report(s), ensuring appropriate project assignment(s) and balance between career development and business needs.
+ Fosters collaboration and connections amongst peers.
+ Cultivates high quality relationships with each direct report to create a trusting environment.
+ Participates in Initiatives to foster talent development.
**Keys to Success:**
+ Advanced degree (Master or PhD) in a health-related discipline or equivalent experience.
+ At least 10 years of drug development experience across different disease areas.
+ At least 5 years of program management experience in the pharmaceutical or biotech industry.
**Knowledge, Skills, Abilities**
+ Strong leadership, communication, and collaborative skills.
+ Proven ability to mediate conflict and manage change.
+ Advanced project management skills and experience with MS Project.
+ PMP certification is an advantage.
+ Fluent in English (verbal and written).
+ Experience in Regulatory Affairs and/or Clinical Development is a plus.
PPD values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive. Below is listed the working environment/requirements for this role:
+ Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
+ Able to work upright and stationary for typical working hours.
+ Ability to use and learn standard office equipment and technology with proficiency.
+ May have exposure to potentially hazardous elements typically found in healthcare or laboratory environments.
+ Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.
+ May require travel. (Recruiter will provide more details.)
Our Mission is to enable our customers to make the world healthier, cleaner and safer. Watch as our colleagues explain 5 reasons to work with us. As one team of 100,000+ colleagues, we share a common set of values - Integrity, Intensity, Innovation and Involvement - working together to accelerate research, solve complex scientific challenges, drive technological innovation and support patients in need. #StartYourStory with PPD, part of Thermo Fisher Scientific, where diverse experiences, backgrounds and perspectives are valued.
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Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

Our client is a leading pharmaceutical innovator seeking a highly accomplished Principal Scientist to drive critical drug discovery and development initiatives within their state-of-the-art research facility located in **Bradford, West Yorkshire, UK**. This pivotal role involves leading complex research projects, from target identification and validation through to preclinical development, contributing significantly to the company's pipeline of novel therapeutics. You will leverage your deep scientific expertise and extensive experience to guide research strategies, foster innovation, and ensure the efficient progression of drug candidates.

Key Responsibilities:

• Lead and manage multiple drug discovery projects from concept to preclinical candidate selection.
• Design and execute complex biological experiments to investigate disease mechanisms and identify novel therapeutic targets.
• Develop and optimize assay development strategies for high-throughput screening and compound characterization.
• Analyze and interpret experimental data, making critical decisions on project direction and go/no-go criteria.
• Collaborate closely with internal teams (e.g., medicinal chemistry, pharmacology, DMPK) and external partners to advance drug candidates.
• Stay current with scientific literature and emerging technologies in relevant therapeutic areas and drug discovery methodologies.
• Prepare and present research findings to senior management, scientific committees, and at external conferences.
• Contribute to the development of intellectual property and regulatory submissions.
• Mentor and guide junior scientists, fostering a culture of scientific excellence and collaboration.
• Ensure compliance with all relevant safety, ethical, and regulatory guidelines.

Required Qualifications:

• Ph.D. in Molecular Biology, Biochemistry, Pharmacology, or a closely related life science discipline.
• A minimum of 8-10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
• Demonstrated success in leading drug discovery projects and bringing candidates into preclinical development.
• Extensive knowledge of various drug discovery platforms and modalities (e.g., small molecules, biologics).
• Proficiency in experimental design, data analysis, and interpretation using relevant software.
• Excellent understanding of relevant therapeutic areas (e.g., oncology, immunology, neuroscience).
• Strong leadership, project management, and communication skills.
• Proven ability to work effectively in a multidisciplinary, matrixed environment.
• Experience with manuscript preparation and scientific presentation is essential.
• A strong publication record in peer-reviewed journals is highly desirable.

This is a challenging and rewarding role for a seasoned scientist eager to make a substantial impact on the development of life-saving medicines. Join a dynamic team dedicated to advancing pharmaceutical science in **Bradford, West Yorkshire, UK**.