19 Gsk jobs in the United Kingdom

Our client, a leading pharmaceutical company dedicated to advancing healthcare through innovative drug development, is seeking an experienced and highly skilled Principal Formulation Scientist to join their dynamic R&D team in Nottingham, Nottinghamshire, UK . This critical role will involve leading the development of novel drug delivery systems and innovative formulations for a diverse pipeline of pharmaceutical products. You will be at the forefront of designing, optimizing, and scaling up formulations, ensuring product efficacy, stability, and bioavailability. The ideal candidate will possess a deep understanding of pharmaceutical sciences, particularly in pre-formulation, formulation development, and manufacturing processes. Responsibilities include conducting pre-formulation studies, designing and executing experiments for solid dosage forms, sterile injectables, or other relevant delivery routes, and characterizing formulation performance. You will lead the troubleshooting of formulation challenges and provide expert scientific guidance to project teams. The Principal Formulation Scientist will play a key role in the transition of formulations from laboratory scale to clinical manufacturing and beyond. Collaboration with cross-functional teams, including analytical development, DMPK, regulatory affairs, and manufacturing, is essential. You will also contribute to the scientific strategy of the formulation department, stay abreast of emerging technologies, and potentially mentor junior scientists. A strong publication record and experience with intellectual property development are desirable. This hybrid role offers a blend of essential lab-based work and remote strategic planning and analysis, providing a balanced and productive work environment. This is an excellent opportunity to contribute to life-changing medicines within a supportive and scientifically driven organization in Nottingham .
Qualifications:

• Ph.D. in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related field
• Minimum of 7 years of progressive experience in pharmaceutical formulation development
• Proven expertise in developing various dosage forms (e.g., oral solids, injectables, topical)
• Strong understanding of pre-formulation, excipient selection, and drug-excipient compatibility
• Hands-on experience with formulation characterization techniques (e.g., DSC, TGA, XRPD, dissolution)
• Experience with pilot-scale formulation manufacturing and technology transfer
• Knowledge of GMP guidelines and regulatory requirements for drug development
• Excellent problem-solving, analytical, and critical thinking skills
• Strong project management and organizational abilities
• Effective communication and interpersonal skills for cross-functional collaboration
• Ability to mentor junior scientists and contribute to scientific strategy
• Experience with specific therapeutic areas is a plus

Our client, a leading pharmaceutical company dedicated to advancing healthcare solutions, is seeking a skilled and innovative Pharmaceutical Formulation Scientist to join their research and development team in Milton Keynes, Buckinghamshire, UK . This role is pivotal in the early-stage development of novel drug formulations, contributing to the creation of effective and patient-centric medicines. The ideal candidate will possess a strong background in pharmaceutical sciences, with hands-on experience in formulation development and characterization. Responsibilities will include:

• Designing, developing, and optimizing oral solid dosage forms (tablets, capsules) and potentially other dosage forms.
• Conducting pre-formulation studies to understand the physicochemical properties of active pharmaceutical ingredients (APIs) and excipients.
• Evaluating and selecting appropriate excipients to achieve desired drug release profiles and stability.
• Utilizing various laboratory techniques for formulation preparation and characterization (e.g., particle size analysis, dissolution testing, differential scanning calorimetry).
• Developing and validating analytical methods for drug product testing.
• Conducting stability studies to assess the shelf-life and performance of formulations under various conditions.
• Troubleshooting formulation challenges and proposing innovative solutions.
• Collaborating with analytical development, process development, and regulatory affairs teams.
• Documenting experimental procedures, results, and reports in accordance with company standards and regulatory guidelines.
• Staying current with scientific literature and industry trends in pharmaceutical formulation and drug delivery.

The successful candidate will hold a Bachelor's or Master's degree in Pharmacy, Pharmaceutical Sciences, Chemistry, or a related discipline. A minimum of 3-5 years of relevant experience in pharmaceutical formulation development within the industry is required. Hands-on experience with common formulation equipment and analytical instrumentation is essential. Knowledge of regulatory guidelines related to drug product development (e.g., ICH) is highly desirable. Excellent problem-solving, critical thinking, and organizational skills are necessary. Strong written and verbal communication abilities are important for effective collaboration within the R&D team. This role offers a competitive salary, comprehensive benefits, and the opportunity to contribute to the development of impactful medicines within our client's state-of-the-art facilities in Milton Keynes, Buckinghamshire, UK , with a hybrid working model.

Our client, a leading innovator in pharmaceutical research and development, is seeking a highly skilled and motivated Senior Formulation Scientist to join their dynamic team. This is an exciting opportunity to contribute to the development of cutting-edge therapeutic agents from pre-clinical stages through to clinical trials. The role will involve extensive laboratory work, data analysis, and collaboration with cross-functional teams.

Key Responsibilities:

• Design, develop, and optimize novel drug delivery systems and formulations for various routes of administration (e.g., oral, injectable, topical).
• Conduct pre-formulation studies, including API characterization, solubility enhancement, and stability assessment.
• Perform compatibility studies and develop analytical methods for drug substance and drug product characterization.
• Utilize a range of formulation technologies and equipment, including granulation, coating, lyophilization, and sterile manufacturing processes.
• Execute experiments meticulously, document all findings accurately in laboratory notebooks and reports, and present results to project teams and management.
• Troubleshoot formulation challenges and propose innovative solutions.
• Collaborate closely with analytical chemists, process engineers, and clinical development teams to ensure successful project progression.
• Stay abreast of the latest scientific literature, regulatory guidelines, and industry trends in pharmaceutical formulation.
• Contribute to the preparation of regulatory submission documents (e.g., IND, NDA).

Qualifications and Experience:

• PhD or MSc in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related field.
• Minimum of 5 years of relevant experience in pharmaceutical formulation development, preferably within an R&D setting.
• Proven track record in developing various dosage forms, with a strong understanding of formulation science principles.
• Hands-on experience with laboratory equipment for formulation development and characterization.
• Proficiency in relevant analytical techniques (e.g., HPLC, GC, DSC, TGA, XRPD).
• Excellent understanding of Good Manufacturing Practice (GMP) and regulatory requirements.
• Strong problem-solving skills, attention to detail, and ability to work independently and as part of a team.
• Effective communication and interpersonal skills.

This role is based in Leicester, Leicestershire, UK and offers a hybrid working model, balancing in-office collaboration with remote flexibility. Join us and make a tangible impact on patient lives through groundbreaking pharmaceutical innovations.

Our client, a leading biopharmaceutical innovator, is seeking a highly motivated Senior Clinical Research Scientist to join their cutting-edge oncology research team. This fully remote position offers the unique opportunity to contribute significantly to the development of novel cancer therapies from anywhere in the UK. You will be at the forefront of scientific advancement, playing a pivotal role in the design, execution, and interpretation of clinical trials that have the potential to transform patient lives.

Key Responsibilities:

• Design and develop clinical trial protocols for oncology assets, ensuring scientific rigor and regulatory compliance.
• Oversee the execution of clinical studies, providing scientific and medical expertise to cross-functional teams.
• Analyze and interpret complex clinical trial data, including efficacy and safety endpoints.
• Collaborate with regulatory affairs, statistics, and medical writing teams to prepare submissions and publications.
• Stay abreast of the latest scientific advancements, emerging trends, and competitive landscape in oncology drug development.
• Identify and engage with key opinion leaders (KOLs) and investigators in the field.
• Contribute to the strategic planning and decision-making processes for the oncology portfolio.
• Develop and present scientific data internally and externally at conferences and meetings.
• Ensure adherence to Good Clinical Practice (GCP) guidelines and all relevant regulations.
• Mentor junior scientists and contribute to the growth of the research department.

Qualifications and Experience:

• Ph.D. or M.D. in a relevant life science discipline (e.g., Oncology, Immunology, Pharmacology).
• Minimum of 5-7 years of experience in clinical research and drug development, with a significant focus on oncology.
• Demonstrated experience in designing and managing complex clinical trials (Phase I-III).
• In-depth knowledge of oncology disease areas, drug mechanisms, and current treatment paradigms.
• Strong understanding of regulatory requirements (FDA, EMA) and GCP.
• Excellent analytical, statistical interpretation, and problem-solving skills.
• Exceptional written and verbal communication skills, with a proven track record of scientific publications and presentations.
• Ability to work effectively in a remote, fast-paced, and collaborative environment.
• Experience with data management systems and statistical analysis software is a plus.
• Strong leadership potential and ability to influence cross-functional teams.

This is a crucial role for an accomplished scientist passionate about making a difference in the fight against cancer. Join our innovative client and shape the future of oncology treatments.

Our client, a leading pharmaceutical innovator, is seeking a highly accomplished Principal Clinical Research Scientist to spearhead critical oncology drug development programs. This role requires a deep scientific understanding of cancer biology, extensive experience in clinical trial design and execution, and a passion for bringing life-changing therapies to patients. You will collaborate with world-class researchers and clinicians to advance novel treatments from early-stage research through to regulatory submission.

Responsibilities:

• Lead the scientific strategy and design of Phase I-III clinical trials for novel oncology therapeutics.
• Oversee the development of clinical protocols, investigator brochures, and other essential study documents.
• Provide scientific and clinical expertise to cross-functional teams, including clinical operations, data management, regulatory affairs, and biomarker development.
• Analyze and interpret complex clinical trial data, translating findings into strategic recommendations for drug development.
• Prepare high-quality scientific publications, abstracts, and presentations for key medical conferences and journals.
• Engage with key opinion leaders (KOLs) in oncology to gather insights and foster collaboration.
• Contribute to regulatory submissions (e.g., IND, NDA) by preparing relevant clinical sections.
• Stay abreast of the latest advancements in oncology research, emerging therapeutic modalities, and competitive landscape.
• Mentor and guide junior scientists and clinical development professionals.
• Ensure all clinical research activities comply with GCP, regulatory guidelines, and company policies.

Qualifications:

• Ph.D. or M.D. in a relevant life sciences discipline (e.g., Oncology, Immunology, Molecular Biology).
• Minimum of 10 years of experience in clinical drug development, with a strong focus on oncology.
• Demonstrated success in designing and leading complex clinical trials.
• Expertise in cancer biology, tumor microenvironment, and current therapeutic strategies.
• In-depth knowledge of GCP, regulatory requirements, and clinical trial methodologies.
• Proven ability to analyze and interpret clinical data effectively.
• Excellent scientific writing and communication skills, with a track record of publications and presentations.
• Strong leadership capabilities and experience working in a matrixed environment.
• Ability to travel to Glasgow, Scotland, UK as required for key meetings and site visits.
• Experience with immuno-oncology and targeted therapies is highly desirable.

This is a key role within our client's innovative pipeline, offering the chance to shape the future of cancer treatment.

**Work Schedule**
Standard (Mon-Fri)
**Environmental Conditions**
Office
**Job Description**
At Thermo Fisher Scientific, you'll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on - now and in the future.
**The PPD FSP Solution:**
PPD's Functional Service Provider division partner with and serve as an extension of our PPD team, supporting our customers key functions. We cover customer needs on every level, allowing them to do more with less, with an uncompromising commitment to quality. We deploy the same top-tier talent in ALL engagement models. Exceptionally trained, rigorously supported and technologically empowered to help customers manage capacity and set programs up for success.
Joining within our PPD FSP functional area, allows you to join the renowned PPD CRO and still gain invaluable client dedicated experience.
_Our client, a global mid-sized biotech company, focuses on developing innovative treatments for patients with autoimmune diseases. This fast-growing, international organization has a strong scientific foundation. If you're looking for a place where your work, in partnership with others, can have real impact-and where you're encouraged challenge yourself and contribute to breakthrough solutions , the_ **_A_** **_ssociate Director, Drug Development_** _role could be a great fit._
**Discover Impactful Work:**
The Associate Director within Drug Development will oversee high-level plans and progress for asset development, from pre-clinical stages to commercial launch. This role involves close collaboration with various stakeholders to ensure timely availability of documents and alignment with corporate strategy. Act as primary point of contact when concerning integrated cross-functional project planning and status. They closely collaborate with stakeholders who own, contribute to, and/or manage the project and the impact of decisions and changing circumstances. This to drive timely availability of documents as planned.
**A day in the Life:**
_Project Lead responsibilities:_
+ Serves as the primary contact between the sponsor and the organization at the project level.
+ On projects where the scope requires, ensures clear delineation in responsibilities and communication pathways for secondary project leads (such as lead in a specific region, lead for a specific vendor(s) or subset of delivery).
+ Drives and owns the overall delivery of the cross-functional project (time, cost, quality).
+ Ensures financial stewardship at a project level by demonstrating an intimate understanding of the contract, resource alignment to budget, management of Out of Scope activity, drive the Con Mod process/negotiations and team execution to timelines.
+ Establishes, communicates and manages customer expectations to achieve optimal delivery during the project.
+ Drives Risk Identification and Issue Resolution at project level (RBQM/RESOLVE).
+ Ensures project team compliance with organization policies, SOPs, ICH- GCP, regulatory and project specific requirements
_Oversight Director responsibilities:_
+ Accountable for strategic indication or client-specific portfolio management within a Therapeutic Unit.
+ Expertly navigates the need to dive in/dive out of situations while ensuring the Project Lead remains empowered .
+ Provokes critical thinking in Project Lead related to execution of delivery, financial negotiations and prioritization.
+ Provides insight into proposal strategy in prep for bid defense.
+ Works with Therapeutic Unit Head in development of business growth strategies.
+ Maintains awareness and engages as appropriate in the Con Mod process.
+ Communicates with People Manager(s) to support the development of the employee providing expertise and perspective related to client needs, indication and therapeutic knowledge.
_People Manager responsibilities:_
+ Accountable for the career development and performance management of a group of project delivery direct reports in line with The Core People Manager Expectations at the organization.
+ Partners with project team leadership and key stakeholders (i.e OD, SLT, BPL, DevOps, functional leadership) to ensure areas of development, training needs and coaching are aligned through routine and active engagement.
+ Provides coaching, soft skill and technical skill development to grow our Project Delivery talent.
+ Provides support/direction to direct report(s) with regards to knowledge of organization systems, processes and tools within Project Delivery.
+ Liaises with Resourcing Leads, TU Leadership and other key stakeholders to advocate for direct report(s), ensuring appropriate project assignment(s) and balance between career development and business needs.
+ Fosters collaboration and connections amongst peers.
+ Cultivates high quality relationships with each direct report to create a trusting environment.
+ Participates in Initiatives to foster talent development.
**Keys to Success:**
+ Advanced degree (Master or PhD) in a health-related discipline or equivalent experience.
+ At least 10 years of drug development experience across different disease areas.
+ At least 5 years of program management experience in the pharmaceutical or biotech industry.
**Knowledge, Skills, Abilities**
+ Strong leadership, communication, and collaborative skills.
+ Proven ability to mediate conflict and manage change.
+ Advanced project management skills and experience with MS Project.
+ PMP certification is an advantage.
+ Fluent in English (verbal and written).
+ Experience in Regulatory Affairs and/or Clinical Development is a plus.
PPD values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive. Below is listed the working environment/requirements for this role:
+ Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
+ Able to work upright and stationary for typical working hours.
+ Ability to use and learn standard office equipment and technology with proficiency.
+ May have exposure to potentially hazardous elements typically found in healthcare or laboratory environments.
+ Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.
+ May require travel. (Recruiter will provide more details.)
Our Mission is to enable our customers to make the world healthier, cleaner and safer. Watch as our colleagues explain 5 reasons to work with us. As one team of 100,000+ colleagues, we share a common set of values - Integrity, Intensity, Innovation and Involvement - working together to accelerate research, solve complex scientific challenges, drive technological innovation and support patients in need. #StartYourStory with PPD, part of Thermo Fisher Scientific, where diverse experiences, backgrounds and perspectives are valued.
Apply today! Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.
Accessibility/Disability Access
Job Seekers with a Disability: Thermo Fisher Scientific offers accessibility service for job seekers requiring accommodations in the job application process. For example, this may include individuals requiring assistance because of hearing, vision, mobility, or cognitive impairments. If you are a job seeker with a disability, or assisting a person with a disability, and require accessibility assistance or an accommodation to apply for one of our jobs, please submit a request by telephone at *. Please include your contact information and specific details about your required accommodation to support you during the job application process.
This telephone line is reserved solely for job seekers with disabilities requiring accessibility assistance or an accommodation in the job application process. Messages left for other purposes, such as not being able to get into the career website, following up on an application, or other non-disability related technical issues will not receive a response.
Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

Our client, a pioneering biotechnology company at the forefront of therapeutic innovation, is seeking a highly accomplished Principal Scientist to lead critical research initiatives within their Drug Discovery & Development division. Based in Milton Keynes, Buckinghamshire, UK , this role is integral to advancing novel treatment modalities from early-stage research through to preclinical development. The successful candidate will bring a wealth of scientific expertise, a proven track record in research leadership, and a passion for translating scientific breakthroughs into life-changing medicines. This is a lab-based role requiring hands-on involvement and direct oversight of research activities.

Key Responsibilities:

• Design, execute, and interpret complex experiments to drive drug discovery programmes forward.
• Lead and mentor a team of talented research scientists and technicians, fostering a culture of scientific excellence and collaboration.
• Develop and validate novel assays and technologies to support drug discovery efforts.
• Identify and evaluate promising therapeutic targets and lead compounds.
• Oversee preclinical studies, including in vitro and in vivo models, to assess compound efficacy and safety.
• Collaborate effectively with cross-functional teams, including chemistry, pharmacology, toxicology, and translational science.
• Author high-quality scientific reports, manuscripts, and patent applications.
• Present research findings at internal meetings and external scientific conferences.
• Manage external collaborations with academic institutions and contract research organizations (CROs).
• Contribute to strategic planning for the R&D pipeline and portfolio management.
• Ensure compliance with all relevant laboratory safety regulations and best practices.
• Stay abreast of the latest scientific advancements and competitive landscape in relevant therapeutic areas.

Required Qualifications and Expertise:

• Ph.D. in Pharmacology, Molecular Biology, Biochemistry, Immunology, or a related life science discipline.
• Minimum of 10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry, with a strong focus on drug discovery.
• Demonstrated leadership experience in managing scientific teams and projects.
• Deep expertise in (Specific therapeutic area relevant to fictional company, e.g., oncology, infectious diseases, neuroscience) and associated drug discovery methodologies.
• Proficiency in a wide range of in vitro and in vivo experimental techniques.
• Proven ability to design and execute complex research strategies and troubleshoot effectively.
• Excellent analytical, problem-solving, and critical thinking skills.
• Exceptional written and verbal communication skills, with a track record of publications and presentations.
• Experience with biostatistics and data analysis software.
• Strong project management skills and the ability to manage multiple priorities.
• A passion for scientific innovation and a commitment to developing novel therapeutics.

This is an exceptional opportunity for a distinguished scientist to make a significant impact on the future of medicine. Join a world-class research team and contribute to the development of groundbreaking therapies.

Our client, a renowned pharmaceutical research and development company located in Glasgow, Scotland, UK , is seeking a highly accomplished Principal Scientist to lead critical initiatives in drug discovery and development. This senior role is responsible for driving innovation, designing experimental strategies, and executing complex research projects aimed at identifying and advancing novel therapeutic candidates. You will play a key part in shaping the company's R&D pipeline, leveraging your deep scientific expertise to overcome research challenges and accelerate the progression of drug candidates through preclinical and early clinical stages. The ideal candidate will possess a strong track record in medicinal chemistry, pharmacology, or a related discipline, with a comprehensive understanding of the drug discovery process from target identification to candidate selection. Proven experience in leading scientific teams, managing research projects, and mentoring junior scientists is essential. You must demonstrate excellent analytical and problem-solving skills, with the ability to interpret complex data, draw insightful conclusions, and make critical research decisions. Strong communication and presentation skills are required to effectively convey scientific findings to internal stakeholders, including senior management and cross-functional teams, as well as external collaborators. Proficiency with relevant laboratory techniques, data analysis software, and scientific literature databases is expected. This hybrid position offers the benefit of collaborative laboratory work and team meetings, combined with the flexibility of focused remote work. We are looking for a visionary scientific leader with a passion for innovation and a commitment to developing life-changing medicines. A Ph.D. in a relevant scientific field (e.g., Pharmacology, Medicinal Chemistry, Biochemistry) and a minimum of 10 years of progressive experience in the pharmaceutical industry are required. Join our esteemed team in Glasgow and make a significant impact on global health.

Our client, a rapidly growing pharmaceutical company dedicated to discovering and developing life-changing medicines, is seeking a highly accomplished Principal Scientist to join their remote-first research team. This pivotal role is essential for driving innovation in drug discovery and development. You will leverage your deep scientific expertise to design and execute complex research projects, mentor junior scientists, and contribute to strategic decision-making. This is an exceptional opportunity to make a tangible impact on patient lives from the comfort of your home office.

Key Responsibilities:

• Lead and execute complex research projects focused on novel therapeutic targets and drug candidates.
• Design and implement in vitro and in vivo experimental studies to assess drug efficacy, safety, and pharmacokinetics.
• Analyze and interpret complex biological data, drawing insightful conclusions and proposing next steps.
• Develop and validate new assays and methodologies to support drug discovery programs.
• Collaborate effectively with internal teams (chemistry, biology, DMPK) and external partners to advance pipeline projects.
• Provide scientific leadership and mentorship to junior scientists and research associates.
• Stay at the forefront of scientific literature, identifying emerging trends and opportunities in pharmaceutical research.
• Prepare high-quality scientific reports, presentations, and manuscripts for internal and external dissemination.
• Contribute to the strategic direction of the company's research pipeline and portfolio.

Qualifications:

• PhD in Molecular Biology, Pharmacology, Biochemistry, or a related life science discipline.
• 10+ years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
• Proven track record of successfully leading drug discovery projects from target identification through preclinical development.
• Extensive experience with various biological assays, molecular biology techniques, and cell-based models.
• Strong understanding of immunology, oncology, or other relevant therapeutic areas.
• Demonstrated ability to design, execute, and interpret complex experiments.
• Exceptional critical thinking, problem-solving, and analytical skills.
• Excellent written and verbal communication skills, with a talent for presenting complex scientific information.
• Experience mentoring and managing scientific staff is essential.

This fully remote position, located conceptually near Stoke-on-Trent, Staffordshire, UK , offers a unique chance to join a forward-thinking organisation committed to scientific excellence and innovation in pharmaceutical research. If you are a visionary scientist ready to lead groundbreaking research, we want to hear from you.