1,117 High Throughput Screening jobs in the United Kingdom
Senior Molecular Biologist - Assay Development
Posted 20 days ago
Job Viewed
Job Description
Responsibilities:
- Design, develop, optimize, and validate novel molecular assays for various applications (e.g., target identification, biomarker discovery, drug screening).
- Perform hands-on laboratory experiments using a range of molecular biology techniques, including PCR, qPCR, ddPCR, cloning, DNA/RNA extraction, and library preparation for NGS.
- Develop and optimize immunoassay formats (e.g., ELISA, Western Blot) and cell-based assays.
- Troubleshoot experimental issues and implement solutions to ensure assay robustness and reproducibility.
- Analyze and interpret complex experimental data, generate high-quality reports, and present findings to internal teams and stakeholders.
- Contribute to the scientific strategy and project planning for assay development initiatives.
- Stay current with the latest advancements in molecular biology, assay technologies, and relevant scientific literature.
- Collaborate effectively with computational biologists, chemists, and other scientists.
- Ensure compliance with laboratory safety protocols and maintain accurate experimental records.
- Mentor and guide junior research associates and scientists.
- Ph.D. in Molecular Biology, Biochemistry, Genetics, or a related life science discipline.
- Minimum of 6-8 years of relevant post-doctoral or industry experience in molecular biology assay development.
- Extensive hands-on experience with a broad spectrum of molecular biology techniques.
- Proven expertise in designing, optimizing, and validating assays, particularly qPCR, ddPCR, and NGS library preparation.
- Experience with immunoassay and/or cell-based assay development is highly desirable.
- Strong data analysis and interpretation skills, with proficiency in relevant software.
- Excellent problem-solving, critical thinking, and communication skills.
- Ability to work independently and collaboratively in a remote research environment.
- Strong publication record in peer-reviewed journals.
Clinical Assay Development Scientist | IVD | Diagnostics | AI | Blood-Based Assays | HealthTech |...
Posted today
Job Viewed
Job Description
Hello!
We're looking for an awesome Clinical Assay Development Scientist to join our team on our journey to revolutionize personalized medicine.
About your Role
- Lead the identification, validation, and application of novel blood biomarkers for disease prediction, prognosis, and treatment stratification
- Direct large-scale clinical studies, ensuring compliance with regulatory and ethical standards (GCP/GLP, ISO 13485, IVDR, UKCA)
- Design, optimize, and validate blood-based clinical assays with high robustness, accuracy, and reproducibility.
- Oversee biological sample preparation and processing under biosafety standards, and safety compliance.
- Ensure data integrity through rigorous documentation (validation plans, reports, SOPs, lab notebooks), keeping outputs audit-ready.
- Provide scientific and strategic guidance on biomarker development, clinical study design, and AI/photonics-based diagnostics.
- Establish and manage collaborations with academic, clinical, and industry partners to accelerate biomarker discovery and validation.
- Provide scientific and strategic guidance to internal and external stakeholders on biomarker development, clinical study design, and regulatory requirements specific to photonics and AI-based diagnostics
- Communicate findings and technical insights clearly to both specialist and non-technical audiences; author validation protocols, technical summaries, and regulatory documentation.
Cultural Skills ️
- Builder’s mindset with high ownership, urgency, and empathy.
- Low‑ego, highly collaborative leader who elevates others.
- Mission‑driven and patient‑centered.
This role is based in London and collaborates with teams across the UK and Europe.
Technical / Professional Skills ️
- PhD in a relevant Life Sciences field - biology, medicine, biomedical engineering, molecular biology, others.
- + 3 years relevant experience in the development/validation of blood biomarkers. Bonus: Spectral or AI Biomarkers
- Extensive knowledge and hands-on experience in blood biomarker discovery, validation, and clinical translation. Bonus: analytical assay development
- Familiarity with ISO 13485, IVDR, UKCA, and GCP/GLP expectations.
- Proficiency in applying statistical analysis and data interpretation methods to biomarker discovery and validation studies.
- Strong hands‑on experience with biosafety protocols, clinical sample handling, and assay preparation.
- Exceptional attention to detail and documentation discipline supporting data integrity.
- Excellent communicator; comfortable collaborating with cross‑functional teams and external partners.
Bonus Skills
- Industry experience is highly desirable, particularly in startup environments. Backgrounds in health tech or deep tech are especially valued.
- Exposure to immunoassays, molecular diagnostics, or multi‑omic platforms.
- Contributions to clinical studies or tech‑transfer in regulated settings.
- Understanding of Optics (spectroscopy, Raman, FTIR or similar techniques)
- Understanding of AI (machine learning, deep learning)
- Experience in IVD blood assay development
iLoF in a nutshell
As personalized medicine becomes the norm, scientists, patients, and healthcare systems worldwide face massive barriers in providing the right treatment to the right patient.
Recognized by CB Insights and Financial Times as one of the most promising Digital Health companies in the world, iLoF is building an AI-powered platform capable of transforming precision medicine.
Our goal is to become the platform that democratizes access to personalized medicine for millions of people living with complex diseases around the globe.
Thanks to our proprietary optical fingerprint library of disease biomarkers and biological profiles we can offer personalized patient screening and stratification in a faster and more affordable way, saving up to 40% of the cost and 70% of the time while enabling a more human patient experience.
Supported by leading institutions like Microsoft Ventures, Mayfield, and the Oxford University, iLoF is currently focusing on validating its platform technology in one of the biggest challenges of our times: Alzheimer's, while maintaining ongoing verticals on Digestive Cancer, Stroke, and Infectious diseases.
Our Team
Clinical Assay Development Scientist | IVD | Diagnostics | AI | Blood-Based Assays | HealthTech |...
Posted today
Job Viewed
Job Description
Hello!
We're looking for an awesome Clinical Assay Development Scientist to join our team on our journey to revolutionize personalized medicine.
About your Role
- Lead the identification, validation, and application of novel blood biomarkers for disease prediction, prognosis, and treatment stratification
- Direct large-scale clinical studies, ensuring compliance with regulatory and ethical standards (GCP/GLP, ISO 13485, IVDR, UKCA)
- Design, optimize, and validate blood-based clinical assays with high robustness, accuracy, and reproducibility.
- Oversee biological sample preparation and processing under biosafety standards, and safety compliance.
- Ensure data integrity through rigorous documentation (validation plans, reports, SOPs, lab notebooks), keeping outputs audit-ready.
- Provide scientific and strategic guidance on biomarker development, clinical study design, and AI/photonics-based diagnostics.
- Establish and manage collaborations with academic, clinical, and industry partners to accelerate biomarker discovery and validation.
- Provide scientific and strategic guidance to internal and external stakeholders on biomarker development, clinical study design, and regulatory requirements specific to photonics and AI-based diagnostics
- Communicate findings and technical insights clearly to both specialist and non-technical audiences; author validation protocols, technical summaries, and regulatory documentation.
Cultural Skills ️
- Builder’s mindset with high ownership, urgency, and empathy.
- Low‑ego, highly collaborative leader who elevates others.
- Mission‑driven and patient‑centered.
This role is based in London and collaborates with teams across the UK and Europe.
Technical / Professional Skills ️
- PhD in a relevant Life Sciences field - biology, medicine, biomedical engineering, molecular biology, others.
- + 3 years relevant experience in the development/validation of blood biomarkers. Bonus: Spectral or AI Biomarkers
- Extensive knowledge and hands-on experience in blood biomarker discovery, validation, and clinical translation. Bonus: analytical assay development
- Familiarity with ISO 13485, IVDR, UKCA, and GCP/GLP expectations.
- Proficiency in applying statistical analysis and data interpretation methods to biomarker discovery and validation studies.
- Strong hands‑on experience with biosafety protocols, clinical sample handling, and assay preparation.
- Exceptional attention to detail and documentation discipline supporting data integrity.
- Excellent communicator; comfortable collaborating with cross‑functional teams and external partners.
Bonus Skills
- Industry experience is highly desirable, particularly in startup environments. Backgrounds in health tech or deep tech are especially valued.
- Exposure to immunoassays, molecular diagnostics, or multi‑omic platforms.
- Contributions to clinical studies or tech‑transfer in regulated settings.
- Understanding of Optics (spectroscopy, Raman, FTIR or similar techniques)
- Understanding of AI (machine learning, deep learning)
- Experience in IVD blood assay development
iLoF in a nutshell
As personalized medicine becomes the norm, scientists, patients, and healthcare systems worldwide face massive barriers in providing the right treatment to the right patient.
Recognized by CB Insights and Financial Times as one of the most promising Digital Health companies in the world, iLoF is building an AI-powered platform capable of transforming precision medicine.
Our goal is to become the platform that democratizes access to personalized medicine for millions of people living with complex diseases around the globe.
Thanks to our proprietary optical fingerprint library of disease biomarkers and biological profiles we can offer personalized patient screening and stratification in a faster and more affordable way, saving up to 40% of the cost and 70% of the time while enabling a more human patient experience.
Supported by leading institutions like Microsoft Ventures, Mayfield, and the Oxford University, iLoF is currently focusing on validating its platform technology in one of the biggest challenges of our times: Alzheimer's, while maintaining ongoing verticals on Digestive Cancer, Stroke, and Infectious diseases.
Our Team
Clinical Assay Development Scientist | IVD | Diagnostics | AI | Blood-Based Assays | HealthTech |...
Posted today
Job Viewed
Job Description
Hello!
We're looking for an awesome Clinical Assay Development Scientist to join our team on our journey to revolutionize personalized medicine.
About your Role
- Lead the identification, validation, and application of novel blood biomarkers for disease prediction, prognosis, and treatment stratification
- Direct large-scale clinical studies, ensuring compliance with regulatory and ethical standards (GCP/GLP, ISO 13485, IVDR, UKCA)
- Design, optimize, and validate blood-based clinical assays with high robustness, accuracy, and reproducibility.
- Oversee biological sample preparation and processing under biosafety standards, and safety compliance.
- Ensure data integrity through rigorous documentation (validation plans, reports, SOPs, lab notebooks), keeping outputs audit-ready.
- Provide scientific and strategic guidance on biomarker development, clinical study design, and AI/photonics-based diagnostics.
- Establish and manage collaborations with academic, clinical, and industry partners to accelerate biomarker discovery and validation.
- Provide scientific and strategic guidance to internal and external stakeholders on biomarker development, clinical study design, and regulatory requirements specific to photonics and AI-based diagnostics
- Communicate findings and technical insights clearly to both specialist and non-technical audiences; author validation protocols, technical summaries, and regulatory documentation.
Cultural Skills ️
- Builder’s mindset with high ownership, urgency, and empathy.
- Low‑ego, highly collaborative leader who elevates others.
- Mission‑driven and patient‑centered.
This role is based in London and collaborates with teams across the UK and Europe.
Technical / Professional Skills ️
- PhD in a relevant Life Sciences field - biology, medicine, biomedical engineering, molecular biology, others.
- + 3 years relevant experience in the development/validation of blood biomarkers. Bonus: Spectral or AI Biomarkers
- Extensive knowledge and hands-on experience in blood biomarker discovery, validation, and clinical translation. Bonus: analytical assay development
- Familiarity with ISO 13485, IVDR, UKCA, and GCP/GLP expectations.
- Proficiency in applying statistical analysis and data interpretation methods to biomarker discovery and validation studies.
- Strong hands‑on experience with biosafety protocols, clinical sample handling, and assay preparation.
- Exceptional attention to detail and documentation discipline supporting data integrity.
- Excellent communicator; comfortable collaborating with cross‑functional teams and external partners.
Bonus Skills
- Industry experience is highly desirable, particularly in startup environments. Backgrounds in health tech or deep tech are especially valued.
- Exposure to immunoassays, molecular diagnostics, or multi‑omic platforms.
- Contributions to clinical studies or tech‑transfer in regulated settings.
- Understanding of Optics (spectroscopy, Raman, FTIR or similar techniques)
- Understanding of AI (machine learning, deep learning)
- Experience in IVD blood assay development
iLoF in a nutshell
As personalized medicine becomes the norm, scientists, patients, and healthcare systems worldwide face massive barriers in providing the right treatment to the right patient.
Recognized by CB Insights and Financial Times as one of the most promising Digital Health companies in the world, iLoF is building an AI-powered platform capable of transforming precision medicine.
Our goal is to become the platform that democratizes access to personalized medicine for millions of people living with complex diseases around the globe.
Thanks to our proprietary optical fingerprint library of disease biomarkers and biological profiles we can offer personalized patient screening and stratification in a faster and more affordable way, saving up to 40% of the cost and 70% of the time while enabling a more human patient experience.
Supported by leading institutions like Microsoft Ventures, Mayfield, and the Oxford University, iLoF is currently focusing on validating its platform technology in one of the biggest challenges of our times: Alzheimer's, while maintaining ongoing verticals on Digestive Cancer, Stroke, and Infectious diseases.
Our Team
Clinical Assay Development Scientist | IVD | Diagnostics | AI | Blood-Based Assays | HealthTech |...
Posted today
Job Viewed
Job Description
Hello!
We're looking for an awesome Clinical Assay Development Scientist to join our team on our journey to revolutionize personalized medicine.
About your Role
- Lead the identification, validation, and application of novel blood biomarkers for disease prediction, prognosis, and treatment stratification
- Direct large-scale clinical studies, ensuring compliance with regulatory and ethical standards (GCP/GLP, ISO 13485, IVDR, UKCA)
- Design, optimize, and validate blood-based clinical assays with high robustness, accuracy, and reproducibility.
- Oversee biological sample preparation and processing under biosafety standards, and safety compliance.
- Ensure data integrity through rigorous documentation (validation plans, reports, SOPs, lab notebooks), keeping outputs audit-ready.
- Provide scientific and strategic guidance on biomarker development, clinical study design, and AI/photonics-based diagnostics.
- Establish and manage collaborations with academic, clinical, and industry partners to accelerate biomarker discovery and validation.
- Provide scientific and strategic guidance to internal and external stakeholders on biomarker development, clinical study design, and regulatory requirements specific to photonics and AI-based diagnostics
- Communicate findings and technical insights clearly to both specialist and non-technical audiences; author validation protocols, technical summaries, and regulatory documentation.
Cultural Skills ️
- Builder’s mindset with high ownership, urgency, and empathy.
- Low‑ego, highly collaborative leader who elevates others.
- Mission‑driven and patient‑centered.
This role is based in London and collaborates with teams across the UK and Europe.
Technical / Professional Skills ️
- PhD in a relevant Life Sciences field - biology, medicine, biomedical engineering, molecular biology, others.
- + 3 years relevant experience in the development/validation of blood biomarkers. Bonus: Spectral or AI Biomarkers
- Extensive knowledge and hands-on experience in blood biomarker discovery, validation, and clinical translation. Bonus: analytical assay development
- Familiarity with ISO 13485, IVDR, UKCA, and GCP/GLP expectations.
- Proficiency in applying statistical analysis and data interpretation methods to biomarker discovery and validation studies.
- Strong hands‑on experience with biosafety protocols, clinical sample handling, and assay preparation.
- Exceptional attention to detail and documentation discipline supporting data integrity.
- Excellent communicator; comfortable collaborating with cross‑functional teams and external partners.
Bonus Skills
- Industry experience is highly desirable, particularly in startup environments. Backgrounds in health tech or deep tech are especially valued.
- Exposure to immunoassays, molecular diagnostics, or multi‑omic platforms.
- Contributions to clinical studies or tech‑transfer in regulated settings.
- Understanding of Optics (spectroscopy, Raman, FTIR or similar techniques)
- Understanding of AI (machine learning, deep learning)
- Experience in IVD blood assay development
iLoF in a nutshell
As personalized medicine becomes the norm, scientists, patients, and healthcare systems worldwide face massive barriers in providing the right treatment to the right patient.
Recognized by CB Insights and Financial Times as one of the most promising Digital Health companies in the world, iLoF is building an AI-powered platform capable of transforming precision medicine.
Our goal is to become the platform that democratizes access to personalized medicine for millions of people living with complex diseases around the globe.
Thanks to our proprietary optical fingerprint library of disease biomarkers and biological profiles we can offer personalized patient screening and stratification in a faster and more affordable way, saving up to 40% of the cost and 70% of the time while enabling a more human patient experience.
Supported by leading institutions like Microsoft Ventures, Mayfield, and the Oxford University, iLoF is currently focusing on validating its platform technology in one of the biggest challenges of our times: Alzheimer's, while maintaining ongoing verticals on Digestive Cancer, Stroke, and Infectious diseases.
Our Team
Principal Scientist, Drug Discovery
Posted today
Job Viewed
Job Description
Responsibilities:
- Lead and design innovative drug discovery research programmes.
- Identify and validate novel therapeutic targets.
- Develop and execute experimental strategies for drug discovery and characterisation.
- Interpret complex biological and pharmacological data.
- Mentor and guide junior scientists and research associates.
- Collaborate effectively with internal teams, academic partners, and CROs.
- Contribute to patent filings and scientific publications.
- Stay abreast of scientific literature and emerging technologies in drug discovery.
- Contribute to strategic planning and decision-making for the R&D pipeline.
- PhD in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline.
- 10+ years of post-doctoral experience in drug discovery within the pharmaceutical or biotech industry.
- Demonstrated success in leading R&D projects from target identification to lead optimisation.
- Expertise in a specific therapeutic area (e.g., oncology, immunology, neuroscience).
- Proven ability to design and interpret complex biological experiments.
- Excellent scientific communication, presentation, and writing skills.
- Strong leadership and mentorship capabilities.
- Experience with remote collaboration tools and working autonomously.
- Publication record in high-impact scientific journals.
Principal Scientist, Drug Discovery
Posted 1 day ago
Job Viewed
Job Description
Key Responsibilities:
- Design, implement, and interpret complex biological assays and experiments to identify and validate novel drug targets and mechanisms of action.
- Lead cross-functional research teams in the discovery and optimization of small molecule or biologic drug candidates.
- Develop and implement cutting-edge research strategies aligned with therapeutic area objectives.
- Analyze and interpret large datasets using statistical and bioinformatics tools to guide experimental design and decision-making.
- Manage external collaborations with academic institutions and contract research organizations (CROs).
- Author high-quality research reports, manuscripts for publication, and presentations for scientific conferences.
- Contribute to the intellectual property strategy through invention disclosures and patent filings.
- Mentor and train junior scientists, fostering a collaborative and innovative research environment.
- Stay current with the latest scientific literature, technologies, and trends in drug discovery and relevant therapeutic areas.
- Ensure rigorous adherence to laboratory safety protocols and good experimental practices.
- Ph.D. in Molecular Biology, Biochemistry, Pharmacology, or a related life science discipline.
- A minimum of 8 years of post-doctoral and/or industry experience in drug discovery, with a strong publication record.
- Demonstrated expertise in a specific therapeutic area (e.g., oncology, immunology, neurology) and relevant disease biology.
- Proven track record of successfully leading drug discovery projects from target identification through lead optimization.
- Extensive experience with a range of biochemical, cellular, and phenotypic assay development and execution.
- Proficiency in data analysis software and bioinformatics tools.
- Excellent critical thinking, problem-solving, and experimental design skills.
- Strong written and verbal communication skills, with the ability to articulate complex scientific concepts to diverse audiences.
- Experience managing projects and mentoring scientific staff.
- Ability to thrive in a fast-paced, dynamic, and remote research environment.
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Principal Scientist - Drug Discovery
Posted 1 day ago
Job Viewed
Job Description
Responsibilities include leading research projects, mentoring junior scientists, collaborating with cross-functional teams, and presenting findings at international conferences. You will be expected to develop and validate assays, interpret complex data sets, and contribute to the intellectual property portfolio. Exceptional analytical, problem-solving, and communication skills are paramount. You must be adept at scientific literature review, experimental design, and manuscript preparation. Experience with specific therapeutic areas (e.g., oncology, immunology) and proficiency in relevant scientific software and data analysis tools are highly desirable. This role demands a high degree of autonomy, creativity, and scientific rigor. Our client is committed to fostering a collaborative and innovative remote work environment, providing cutting-edge resources and opportunities for professional growth. You will be at the forefront of developing life-changing medicines, contributing significantly to global health.
Principal Scientist - Drug Discovery
Posted 1 day ago
Job Viewed
Job Description
Key responsibilities:
- Lead and manage complex drug discovery projects from target identification through to lead optimization.
- Develop and implement innovative research strategies to address unmet medical needs.
- Design and conduct experiments using cutting-edge techniques in molecular biology, biochemistry, pharmacology, or related fields.
- Analyze and interpret complex datasets, drawing meaningful conclusions to guide research direction.
- Identify and validate novel drug targets and pathways relevant to various disease areas.
- Design and synthesize potential drug molecules, or oversee their design and synthesis by external partners.
- Contribute to the preparation of regulatory submissions and scientific publications.
- Mentor and provide technical guidance to junior scientists and research associates.
- Foster a collaborative research environment and build strong relationships with academic institutions and industry partners.
- Stay at the forefront of scientific literature and emerging technologies in drug discovery and development.
- Manage project budgets and resources effectively, ensuring timely project completion.
The ideal candidate will possess:
- A PhD in a relevant scientific discipline such as Molecular Biology, Biochemistry, Pharmacology, Medicinal Chemistry, or a related field.
- A minimum of 8-10 years of progressive experience in drug discovery within the pharmaceutical or biotechnology industry.
- A proven track record of successfully advancing drug candidates through the preclinical stages.
- Extensive experience in experimental design, data analysis, and interpretation.
- Deep understanding of disease biology and drug discovery principles.
- Expertise in one or more therapeutic areas (e.g., oncology, immunology, neurology, infectious diseases).
- Strong leadership, project management, and communication skills.
- Demonstrated ability to mentor and develop scientific talent.
- Excellent track record of scientific publications and presentations.
- Experience with external collaborations and partnership management is highly desirable.
- Ability to thrive in a remote-first, highly collaborative team environment.
Principal Scientist, Drug Discovery
Posted 2 days ago
Job Viewed
Job Description
The Principal Scientist will lead and execute complex research projects aimed at identifying and validating novel drug targets and developing small molecule therapeutics. This role requires a deep understanding of modern drug discovery principles, including target identification and validation, hit-to-lead optimisation, and preclinical development. You will be responsible for designing and interpreting experiments, analysing complex datasets, and contributing to the strategic direction of the drug discovery pipeline. Expertise in relevant therapeutic areas (e.g., oncology, immunology, neurology) is highly desirable. The ideal candidate will have a proven track record of scientific leadership, excellent problem-solving skills, and the ability to mentor junior scientists. We are looking for an individual who is passionate about scientific excellence and driven by the potential to impact patient lives.
Key Responsibilities:
- Lead and manage multiple drug discovery projects from inception to preclinical candidate nomination.
- Design, execute, and interpret complex experiments in areas such as medicinal chemistry, pharmacology, and biology.
- Identify and validate novel drug targets and therapeutic pathways.
- Drive hit identification and lead optimisation campaigns for small molecule therapeutics.
- Mentor and guide junior scientists, fostering a collaborative and innovative research environment.
- Author scientific publications, patent applications, and regulatory documents.
- Present research findings at internal meetings and external scientific conferences.
- Collaborate effectively with cross-functional teams, including biology, chemistry, DMPK, and toxicology.
- Contribute to the strategic planning and decision-making for the drug discovery portfolio.
- PhD in Pharmacology, Biochemistry, Molecular Biology, Medicinal Chemistry, or a related field.
- 10+ years of progressive experience in pharmaceutical or biotechnology drug discovery.
- Demonstrated success in leading discovery projects and delivering preclinical candidates.
- Expertise in a specific therapeutic area (e.g., oncology, infectious diseases, neuroscience) is highly advantageous.
- Strong understanding of assay development, screening technologies, and structure-activity relationships.
- Excellent written and verbal communication skills, with a strong publication record.
- Proven ability to manage projects, mentor staff, and work effectively in a remote team environment.