459 Icon Plc jobs in the United Kingdom

• Design and develop pharmaceutical formulations for various dosage forms.
• Conduct pre-formulation studies and excipient compatibility testing.
• Optimize formulation parameters and manufacturing processes.
• Perform physical and chemical characterization of drug products.
• Conduct and interpret stability studies according to ICH guidelines.
• Troubleshoot formulation and manufacturing issues.
• Collaborate with analytical development and quality control teams.
• Prepare technical reports, development summaries, and regulatory documentation.
• Stay current with advancements in drug delivery technologies and formulation science.
• Mentor and guide junior formulation scientists.

• MSc or PhD in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related field.
• Minimum of 5 years of experience in pharmaceutical formulation development.
• Strong knowledge of drug delivery systems and dosage form design.
• Proficiency in formulation characterization techniques and analytical methods.
• Understanding of GMP principles and regulatory requirements.
• Excellent problem-solving and critical thinking skills.
• Effective communication and collaboration abilities.
• Experience with solid dosage forms (e.g., tablets, capsules) is highly preferred.

• Design and develop innovative drug formulations and dosage forms.
• Conduct pre-formulation studies and physicochemical characterization.
• Optimize formulation parameters to achieve desired drug product performance.
• Perform stability studies and analyze results to ensure product quality.
• Collaborate with analytical and process development teams.
• Troubleshoot formulation challenges and propose effective solutions.
• Contribute to the preparation of regulatory documentation.
• Stay updated on new technologies and scientific advancements in drug formulation.
• Mentor junior scientists and contribute to team knowledge sharing.

• PhD or Master's degree in Pharmaceutical Sciences, Pharmaceutics, or a related discipline.
• Minimum of 7 years of experience in pharmaceutical formulation development.
• Proven expertise in developing various dosage forms (e.g., oral, parenteral).
• Proficiency in formulation techniques and analytical characterization methods.
• Knowledge of regulatory requirements and guidelines (ICH).
• Strong problem-solving and critical thinking skills.
• Excellent written and verbal communication abilities.
• Experience with advanced drug delivery systems is a plus.

• Lead and manage multiple drug discovery projects, ensuring scientific excellence and timely delivery.
• Design and implement innovative experimental strategies to identify and validate novel drug targets and lead compounds.
• Conduct advanced biochemical, cellular, and pharmacological assays to characterize compound activity and selectivity.
• Develop and optimize synthetic routes for medicinal chemistry programs.
• Analyze complex biological and chemical data, drawing robust conclusions and making data-driven decisions.
• Prepare comprehensive study reports, manuscripts for publication, and regulatory filings.
• Present research findings clearly and effectively to internal teams, senior management, and external collaborators.
• Mentor and train junior scientists and research associates, fostering a collaborative and high-performing team environment.
• Collaborate closely with cross-functional teams including DMPK, toxicology, and clinical development.
• Contribute to the strategic planning of the R&D pipeline and identify new therapeutic opportunities.
• Maintain a deep understanding of the latest scientific literature and technological advancements in the field.

• Ph.D. in Pharmacology, Medicinal Chemistry, Biochemistry, Molecular Biology, or a closely related discipline.
• A minimum of 8 years of post-doctoral research experience in the pharmaceutical or biotechnology industry, with a focus on small molecule drug discovery.
• Demonstrated success in leading preclinical drug discovery projects from initiation to candidate selection.
• Expertise in a specific therapeutic area (e.g., oncology, neuroscience, infectious diseases) is highly desirable.
• Proficiency in modern drug discovery techniques, including high-throughput screening, structure-based drug design, and lead optimization strategies.
• Strong understanding of pharmacokinetics, pharmacodynamics, and drug metabolism.
• Excellent leadership, project management, and communication skills.
• Ability to work effectively in a fast-paced, matrixed organization.
• Strong publication record in peer-reviewed journals and presentations at scientific meetings.

• Lead and manage drug discovery research projects.
• Design and execute complex experimental strategies.
• Identify and validate novel therapeutic targets.
• Develop and optimise assays for compound screening and characterisation.
• Analyse and interpret experimental data, ensuring scientific rigour.
• Guide preclinical development of drug candidates.
• Collaborate with cross-functional research and development teams.
• Mentor and supervise junior scientific staff.

• Lead the development of innovative drug delivery systems and formulations for various dosage forms (e.g., oral, injectable, topical).
• Conduct pre-formulation studies to characterise active pharmaceutical ingredients (APIs) and excipients.
• Design and execute experiments to develop stable and bioavailable drug products.
• Utilise various formulation technologies, including solid dispersions, nanotechnology, and controlled-release systems.
• Perform comprehensive stability studies according to ICH guidelines.
• Characterise formulated drug products using advanced analytical techniques (e.g., HPLC, dissolution testing, particle size analysis).
• Collaborate closely with analytical development, manufacturing, and regulatory affairs teams.
• Prepare scientific reports, technical documentation, and regulatory submission documents.
• Stay abreast of the latest advancements in pharmaceutical formulation and drug delivery.
• Mentor junior scientists and contribute to the scientific growth of the team.

• PhD in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related discipline.
• Minimum of 5-7 years of industry experience in pharmaceutical formulation development.
• Demonstrated expertise in developing various dosage forms and drug delivery systems.
• In-depth understanding of API characterization, excipient compatibility, and formulation stability.
• Proficiency with pharmaceutical analytical techniques and instrumentation.
• Strong knowledge of regulatory guidelines (e.g., FDA, EMA) pertaining to drug product development.
• Excellent scientific thinking, problem-solving, and experimental design skills.
• Effective communication and interpersonal skills, with the ability to work collaboratively in a multidisciplinary team.
• Experience working in a hybrid environment.

• Lead and execute research projects focused on novel drug delivery systems and formulation development.
• Design and conduct experiments to evaluate drug product performance, stability, and bioavailability.
• Develop and validate analytical methods for drug substance and drug product characterisation.
• Prepare comprehensive technical reports, research summaries, and regulatory documentation (e.g., CMC sections).
• Collaborate closely with cross-functional teams including medicinal chemistry, pharmacology, and clinical development.
• Mentor junior scientists and provide technical guidance on research activities.
• Stay abreast of scientific literature, regulatory guidelines, and industry trends in pharmaceutical development.
• Troubleshoot formulation and analytical challenges, proposing innovative solutions.
• Contribute to intellectual property generation through invention disclosures.
• Represent the company at scientific conferences and external meetings.
• Ensure all laboratory activities comply with Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) standards.
• Assist in the scale-up of manufacturing processes from laboratory to pilot and commercial scale.

Help bring science to life and join a leading pharmaceutical company to play a key role in delivering impactful medicines that drives healthcare innovation!

Hobson Prior is seeking a Drug Product Development Specialist to join a dynamic team within Pharmaceutical Development Sciences. This role focuses on injectable drug product manufacturing processes, supporting clinical and regulatory activities. You will collaborate with internal teams and external partners to ensure the successful development and production of sterile drug products.

Please note that to be considered for this role you must have the right to work in this location.

Responsibilities:

• Develop and refine manufacturing processes for injectable drug products from early studies to regulatory approval.
• Select and define manufacturing parameters for clinical production.
• Collaborate with internal teams and external manufacturers to meet project goals.
• Conduct lab studies, analyse data, and document findings (e.g., filter selection, fill volume assessments, compatibility tests).
• Analyse manufacturing data to improve process understanding and performance.
• Perform risk assessments for manufacturing processes.
• Design processes for sterile injectable products in various forms (e.g., liquid, lyophilized powder, pre-filled syringes).
• Support clinical trial preparation and ensure timely production of stability and clinical batches.
• Assist in process validation and ensure compliance with quality standards and regulations.
• Contribute to regulatory submissions and respond to authority queries.
• Investigate and resolve quality-related issues, such as deviations or complaints.
• Facilitate knowledge transfer from late-phase development to commercial production.
• Help improve departmental processes and ways of working.

Key Skills and Requirements:

• Experience in developing or manufacturing liquid drug products in the pharmaceutical industry.
• Familiarity with biopharmaceuticals is a plus.
• Knowledge of aseptic manufacturing processes, including vial, cartridge, and pre-filled syringe filling, is advantageous.
• Understanding of sterile drug product development, including components, process transfer, scale-up, and optimization, is beneficial.

For more information, please contact Jessica Taylor.

If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists visit the 'Contact Us' page.

Hobson Prior is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Hobson Prior is acting as an Employment Agency in relation to this vacancy.

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Job Title: Junior Clinical Research Associate (CRA)

Location: London, UK (Field-based with regular site visits)

Employment Type: Full-time

About the Role:

We are seeking a motivated Junior Clinical Research Associate (CRA) with a minimum of 2 years of independent monitoring experience to join our London-based team. The successful candidate will play a vital role in ensuring the quality and integrity of clinical trials across multiple therapeutic areas. You will conduct 4–6 monitoring visits per month , providing oversight of study sites while maintaining compliance with ICH-GCP, local regulations, and study protocols.

Key Responsibilities:

• Perform routine monitoring visits (site initiation, interim, and close-out) across assigned sites in London and surrounding regions.
• Ensure adherence to protocol, ICH-GCP, and applicable regulatory requirements.
• Verify accuracy and completeness of case report forms (CRFs) against source data.
• Identify and resolve data discrepancies and protocol deviations in collaboration with site staff.
• Maintain effective communication with investigators, site personnel, and internal study teams.
• Prepare and submit timely monitoring reports and follow-up documentation.
• Support investigators and sites in resolving queries and ensuring readiness for audits and inspections.
• Contribute to trial start-up activities when required (e.g., site feasibility, essential document collection).

Requirements:

• Bachelor’s degree in Life Sciences, Nursing, Pharmacy, or related field.
• Minimum 2 years of independent monitoring experience within a CRO, pharmaceutical, or biotech environment.
• Strong knowledge of ICH-GCP and UK clinical trial regulations.
• Excellent organizational and time management skills with the ability to manage multiple sites.
• Willingness to travel frequently (4–6 site visits per month).
• Strong interpersonal and communication skills, both written and verbal.

What We Offer:

• Competitive salary and benefits package.
• Professional development opportunities within a growing clinical operations team.
• Exposure to diverse therapeutic areas and phases of clinical development.
• Supportive work environment with mentorship from senior CRAs.