270 Informatics Nurse jobs in the United Kingdom

**HOW MIGHT YOU DEFY IMAGINATION?**
At Amgen, every challenge is an opportunity. And every opportunity brings the potential to change lives. Our shared mission-to serve patients-has driven our status as one of the world's preeminent biotechnology companies, reaching over 10 million patients worldwide. Leverage your high-level expertise to lead and forge partnerships that advance the biotechnical and biopharmaceutical science that can turn the tide of serious, life-interrupting illnesses.
**DIRECTOR CLINICAL DATA MANAGEMENT**
**Live**
**What You Will Do**
The Amgen Global Clinical Data Management team is looking for an experienced Director to lead our data management team on the aspiration of optimizing and delivering an industry admired clinical evidence platform to deliver innovative medicines to patients with unmet medical needs.
You will lead and manage Data Management (DM) teams within a specific DM operational business unit. The Director will set and drive forward the vision and strategy for DM as a member of the DM and GSO Leadership Team.
You will be accountable for leadership and oversight of the data management organization; ensuring operational excellence and consistency in clinical trial execution. In this role you will be accountable for building and developing a high performing internal data management team, as well as ensuring engagement and alignment of Amgen's strategy and priorities with the Functional Service Provider (FSP).
In this role you will be part of the Global Study Operations (GSO) leadership team, accountable for the delivery of quality clinical trials through industry-leading execution of innovative processes, strong cross-functional partnerships, and best-use of clinical systems and analytics to guide site and study operations. The role will support acceleration of clinical programs and other continuous improvement efforts, applying innovative thinking in shaping future strategy.
Our Global Clinical Data Management Team:
The Global Clinical Data Management Team comprises approximately 50 people. The three Directors, as part of the wider GSO organization and reporting into the Executive Director, Global Study Operations, work together to meet the demands of an industry leading, fast paced, high throughput organization with a commitment to compliance, quality and standards.
**Responsibilities:**
+ Oversight of a distinct DM operational unit (e.g. therapy area, cross-product area)
+ Recruiting, managing and developing staff
+ Global resource planning and assignments
+ Setting of functional goals and objectives
+ Creating and implementing GSO & DM strategies developing, reviewing, implementing and enforcing data standards
+ Ensuring DM processes/systems meet regulatory and business requirements
+ Be an active member of the Leadership Team to provide a foundation for GSO success
**Key activities will include:**
+ Team management including performance, coaching and development
+ Develop, review and implement policies, SOPs and associated documents affecting DM globally
+ Set vision, strategy and direction for DM group; develop annual goals and objectives
+ Accountable for and oversee DM FSP relationships; ensuring goals of product areas and systems groups can be met via the FSP
+ Define and maintain Service Level Agreements and Key Performance Indicators; including oversight of quality and CAPA management
+ Governance oversight -ensure visibility into performance of FSPs to the department
+ Sponsor, Lead and participate in cross functional working groups
+ Resource and budget management for global function Ensure adequate training and capability within area and be accountable for staff compliance with all DM processes
+ Vendor management (development of strategies, contract management, relationship management, etc)
+ Respond to audit/inspection findings
+ Be accountable for and oversee all study deliverables and submission activities for products within group
+ Ensure that status information on DM activities is available and is acted on as needed
**Win**
**What We Expect Of You**
We are all different, yet we all use our unique contributions to serve patients. The data management professional we seek is a collaborator with these qualifications.
+ Degree educated in relevant field or in life science, computer science, business administration or related discipline
+ Extensive experience in data management in the Pharmaceutical or Biotech arena
+ Experience in rare disease therapeutic area in a leadership role
+ Broad experience of working in a global organization
+ Experience at or oversight of outside vendors (CRO's, central labs, imaging vendors, etc)
+ Extensive managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources
+ Strategic and innovative thinker with experience of driving operational excellence
+ Excellent relationship building skills with the ability to influence and make business impact
+ Ability to work collaboratively cross functionally with ability to influence and drive decisions
+ Proven experience within oversight of clinical research suppliers
+ Project management
+ Previous experience in a global, matrix organization
+ Excellent organizational and interpersonal skills
+ Ability to anticipate and problem solve challenging issues
**THRIVE**
**What you can expect of us**
As we work to develop treatments that take care of others, so we work to care for our teammates' professional and personal growth and well-being.
+ Vast opportunities to learn and move up and across our global organization
+ Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
+ Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits
**LOCATION:** Ability to work flexibly from home with regular office work either from our Cambridge or Uxbridge next generation workspace.
**APPLY NOW**
**for a career that defies imagination**
In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.
**careers.amgen.com**
**Equal Opportunity Statement**
Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.

**RESPONSIBILITIES**
+ Serve as primary point of contact for customer on data management deliverables
+ Manage multiple large studies or program of studies (possibly global)
+ Provide leadership and senior support to DTLs on multiple large global programs of global studies
+ Provide project management expertise working with customer data managers, key decision makers, and internal team members to manage continuous process improvements, issue escalation, workload projections, and provide technical expertise
+ Lead direct negotiations with customer, e.g., timelines, financial, process, resources
+ Meet with Data Operations team members on a regular basis to ensure milestones meet timelines and quality deliverables
+ Independently manage DM service delivery with comprehensive DM process and technical expertise in executing projects
+ Serve as the escalation point for unresolved data issues
+ Ensure appropriate resources are assigned to meet project deliverables
+ Create and/or review and sign-off on all data management plan (DMP) documents
+ Manage service performance and provide leadership to identify root causes of issues and implement remedial actions
+ Serve as Subject Matter Expert (SME)
+ Provide leadership and expertise in a specific CDM task or technology
+ Independently manage SOW/budget
+ Independently bring process improvements and solutions to the CDM team/CDM department
+ Lead a focus team or global or local best practice team
+ Provide review and expert opinion in developing, revising, and maintaining core operating procedures and work instructions
**REQUIRED KNOWLEDGE, SKILLS AND ABILITIES**
+ Previous experience and proven competence in managing delivery of multiple global trials through full DM life-cycle (i.e. large trials of at least 1000 patients)
+ Demonstrated expert data management skills and advanced knowledge of the data management process (e.g., therapeutic area, extensive knowledge in DM processes, SAE reconciliation, external data vendor reconciliation)
+ Previous experience and proven competence in handling complex customer negotiations and bid defense meetings independently
+ Knowledge of Medical Terminology, Pharmacology, Anatomy, and/or Physiology
+ Knowledge of operating procedures and work instructions and the ability to apply them in practice
+ Knowledge of Good Clinical Practices and relevant regulatory guidelines
+ Excellent communication, interpersonal, customer service, and teamwork skills
+ Excellent organizational and problem-solving skills
+ Excellent project management skills
+ Ability to work independently
+ Comprehensive understanding of clinical drug development process
+ Ability to establish and maintain effective working relationships with co-workers, managers and customers
**MINIMUM REQUIRED EDUCATION AND EXPERIENCE**
+ Bachelor's Degree, or educational equivalent, in health, clinical, biological or mathematical sciences, or related field
+ Around 7 years direct Data Management experience, including 5 or more years as a CDM project lead; or equivalent combination of education, training and experience
IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create connections that accelerate the development and commercialization of innovative medical treatments. Everything we do is part of a journey to improve patient outcomes and population health worldwide.
To get there, we seek out diverse talent with curious minds and a relentless commitment to innovation and impact. No matter your role, everyone at IQVIA contributes to our shared goal of helping customers improve the lives of patients everywhere. Thank you for your interest in growing your career with us.
EEO Minorities/Females/Protected Veterans/Disabled

Our client, a leading biopharmaceutical company dedicated to advancing patient care through innovative therapies, is seeking a Principal Clinical Data Manager for their facility in Brighton, East Sussex, UK . This critical role involves overseeing the design, development, and implementation of clinical databases for global clinical trials. You will be responsible for ensuring the accuracy, integrity, and quality of clinical trial data in compliance with regulatory requirements (e.g., FDA, EMA) and Good Clinical Practice (GCP) guidelines. This position requires extensive experience in clinical data management, including database design, data validation strategies, and data cleaning processes. You will lead a team of data managers, providing guidance, mentorship, and technical expertise. Key responsibilities include developing and maintaining Data Management Plans (DMPs), establishing data standards, and ensuring adherence to study protocols. You will collaborate closely with clinical operations, biostatistics, and clinical programming teams to ensure timely database lock and efficient data analysis. The Principal Clinical Data Manager will also be involved in vendor management, evaluating and overseeing third-party data management service providers. Experience with Electronic Data Capture (EDC) systems is essential, and proficiency in statistical analysis software is a plus. This role demands strong leadership skills, excellent communication abilities, and a meticulous attention to detail. You will play a pivotal role in ensuring the successful execution of clinical trials, contributing directly to the development of life-saving medications. The role offers a dynamic and challenging work environment with opportunities for professional growth and development. We are looking for an experienced professional who can drive data management excellence and contribute significantly to our mission of improving global health. The hybrid work model allows for a balanced approach, combining essential in-office collaboration with remote flexibility.

Our client, a pioneering pharmaceutical research company, is seeking a talented and driven Senior Clinical Data Scientist to join their rapidly expanding global team. This is a fully remote position, offering the unique opportunity to contribute to life-saving drug development from anywhere in the UK. You will leverage vast datasets, advanced statistical methods, and machine learning techniques to extract critical insights from clinical trial data, accelerating the identification and validation of novel therapeutic targets. This role is crucial for informing clinical strategy, optimizing trial design, and ensuring the safety and efficacy of new treatments. The ideal candidate possesses a strong scientific background combined with exceptional data analytics and programming skills.

Responsibilities:

• Design, develop, and implement sophisticated statistical models and machine learning algorithms to analyze complex clinical trial data, identifying trends, patterns, and predictive indicators.
• Collaborate with clinical operations, biostatistics, and R&D teams to define analytical objectives, data requirements, and key performance indicators for clinical studies.
• Extract, transform, and integrate data from diverse sources, including electronic data capture (EDC) systems, laboratory results, imaging data, and real-world evidence (RWE).
• Develop data visualizations and dashboards to effectively communicate complex findings to both technical and non-technical stakeholders, including senior management and regulatory bodies.
• Contribute to the interpretation of clinical trial results, providing data-driven recommendations for decision-making regarding study progression, drug efficacy, and safety profiles.
• Mentor junior data scientists and analysts, fostering best practices in data science methodologies and code development.
• Stay at the forefront of scientific literature and industry trends in clinical data science, bioinformatics, and computational biology, proactively proposing innovative analytical approaches.
• Ensure the integrity, quality, and reproducibility of all analyses through rigorous validation, documentation, and adherence to data governance policies.
• Assist in the preparation of data sections for regulatory submissions and scientific publications.
• Participate in the evaluation and implementation of new data science tools and technologies to enhance analytical capabilities.
• Communicate complex analytical concepts clearly and concisely to cross-functional teams, ensuring a shared understanding of data-driven insights.
• Champion the ethical use of data and ensure compliance with all relevant data privacy regulations (e.g., GDPR, HIPAA).

Qualifications:

• PhD or Master's degree in a quantitative field such as Biostatistics, Statistics, Computer Science, Bioinformatics, Computational Biology, or a related discipline.
• 5+ years of relevant experience in clinical data analysis within the pharmaceutical or biotechnology industry.
• Proven expertise in statistical modeling, machine learning (e.g., regression, classification, clustering, deep learning), and experimental design.
• Strong programming skills in R and/or Python, including experience with relevant data science libraries (e.g., pandas, scikit-learn, TensorFlow, PyTorch).
• Experience with SQL for data extraction and manipulation.
• Familiarity with clinical trial phases, drug development processes, and regulatory requirements.
• Excellent understanding of data visualization tools and techniques.
• Demonstrated ability to manage and analyze large, complex datasets from multiple sources.
• Strong analytical, problem-solving, and critical thinking skills.
• Exceptional communication and presentation skills, with the ability to explain technical concepts to diverse audiences.
• Ability to work independently and proactively in a remote setting, demonstrating strong organizational and time management skills.
• Experience with cloud computing platforms (AWS, Azure, GCP) is a plus.
• Knowledge of pharmacokinetics/pharmacodynamics (PK/PD) modeling is advantageous.

This is a fully remote role, empowering you to make a significant impact on global health from the comfort of your home.

Our client is looking for a meticulous and experienced Remote Clinical Data Manager to join their innovative pharmaceutical team. This position is fully remote, offering flexibility and the opportunity to work from anywhere within the UK. You will be responsible for overseeing the collection, quality, and integrity of clinical trial data, ensuring compliance with regulatory standards (e.g., GCP, ICH). This role involves close collaboration with clinical operations, biostatistics, and programming teams to design data collection systems, develop data management plans, and manage database lock procedures.

Key responsibilities include developing clinical data management system (CDMS) specifications, creating electronic data capture (EDC) forms, and implementing data validation checks. You will also be responsible for querying data discrepancies, ensuring timely resolution, and performing quality control reviews of datasets. The Remote Clinical Data Manager will contribute to the development of standard operating procedures (SOPs) and work instructions related to data management. Furthermore, you will ensure that all data management activities are documented thoroughly and maintained in accordance with regulatory requirements.

The ideal candidate will possess a Bachelor's degree in a scientific or healthcare-related field, with a minimum of 5 years of experience in clinical data management within the pharmaceutical or biotech industry. Proven experience with EDC systems (e.g., Medidata Rave, Veeva Vault EDC) and a strong understanding of clinical trial processes and regulatory guidelines are essential. Excellent analytical, problem-solving, and organizational skills are required, along with strong attention to detail. The ability to work independently, manage multiple priorities effectively, and communicate clearly in a remote environment is crucial. This is an excellent opportunity for a skilled professional to make a significant impact in drug development while enjoying the benefits of a remote-first work culture.

Our client, a leading pharmaceutical research organisation, is seeking a highly skilled and meticulous Senior Clinical Data Manager to join their innovative global team. This is a critical, fully remote position requiring extensive experience in clinical data management within the pharmaceutical or biotech industry. You will be responsible for ensuring the quality, integrity, and accuracy of clinical trial data from study start-up through database lock and submission. The role involves leading data management activities, developing data management plans, performing data review and cleaning, and ensuring compliance with regulatory standards (e.g., GCP, ICH). As a remote-first role, you will collaborate extensively with study teams, clinical operations, biostatistics, and external vendors to achieve project milestones. This is an exceptional opportunity to contribute to life-saving research from the comfort of your home.

Key Responsibilities:

• Lead and manage clinical data management activities for assigned clinical trials.
• Develop and maintain Data Management Plans (DMPs) in collaboration with cross-functional study teams.
• Design, build, and validate clinical databases (e.g., EDC systems) and data collection tools.
• Oversee data entry, data validation, query generation, and data cleaning processes to ensure data accuracy and completeness.
• Perform data review and reconciliation activities, including SAE reconciliation and external data reconciliation.
• Ensure compliance with all applicable regulatory requirements (GCP, ICH, FDA, EMA) and company SOPs.
• Manage vendor activities related to data management, including EDC providers and central labs.
• Prepare and present data management status updates to project teams and management.
• Participate in the development and implementation of data management standards and best practices.
• Contribute to the validation of data management systems and tools.
• Support database lock activities and ensure the quality of the final clinical database.

Qualifications:

• Bachelor's degree in a scientific, medical, or computational field. Advanced degree preferred.
• Minimum of 7 years of experience in clinical data management in the pharmaceutical or biotech industry.
• Extensive experience with Electronic Data Capture (EDC) systems (e.g., Medidata Rave, Oracle InForm, Veeva EDC).
• Thorough understanding of clinical trial processes, regulatory guidelines (GCP, ICH), and data standards (CDISC).
• Proven ability to manage complex clinical datasets and ensure data quality.
• Strong analytical, problem-solving, and critical thinking skills.
• Excellent communication, interpersonal, and organisational skills.
• Experience in developing DMPs, edit checks, and data validation plans.
• Ability to work independently, manage multiple projects, and meet tight deadlines in a remote environment.
• Proficiency in database management principles.

This role is crucial for our client's success and is based in Belfast, Northern Ireland, UK , though it is a fully remote position, offering maximum flexibility.

Associate Clinical Data Science Programmer
ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.
We are currently seeking an Associate Clinical Data Science Programmer to join our diverse and dynamic team. As an Associate Clinical Data Science Programmer at ICON, you will be instrumental in developing and optimizing clinical data analysis processes and tools that support the delivery of high-quality clinical trial data. Your work will contribute directly to the success of clinical trials by ensuring the accuracy, consistency, and integrity of data, enabling the advancement of innovative treatments and therapies.
**What You Will Be Doing:**
+ Collaborating with clinical teams to develop and implement data processing programs for clinical trials.
+ Programming and validating datasets, tables, listings, and figures (TLFs) for clinical study reports and regulatory submissions.
+ Ensuring data quality and consistency by performing rigorous checks and validation on clinical trial data.
+ Supporting the integration of various data sources to enable comprehensive data analysis and reporting.
+ Contributing to the development of standard operating procedures (SOPs) and best practices for clinical data programming.
**Your Profile:**
+ Bachelor's degree in computer science, data science, statistics, or a related field.
+ Proficiency in programming languages such as SAS, R, or Python, with experience in clinical data management.
+ Strong analytical skills with attention to detail and a commitment to data accuracy.
+ Ability to work collaboratively in a cross-functional team environment.
+ Excellent communication skills, with the ability to explain complex technical concepts to non-technical stakeholders.
**What ICON can offer you:**
Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.
In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.
Our benefits examples include:
+ Various annual leave entitlements
+ A range of health insurance offerings to suit you and your family's needs.
+ Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
+ Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family's well-being.
+ Life assurance
+ Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.
Visit our careers site ( to read more about the benefits ICON offers.
At ICON, inclusion & belonging are fundamental to our culture and values. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here ( in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless - there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.
Are you a current ICON Employee? Please click here ( to apply

The CDM will perform scientific (complex) clinical data review in close collaboration with the Study Responsible Physicians (SRP) and Study Responsible Scientists (SRS).
Deliverables:
- Services rendered will adhere to applicable Client SOPs, WIs, policies, local regulatory requirements, ICH-GCP, etc.
- Provides scientific data review support for more than one low to moderate complexity trial or one high complexity trial.
- The data management expert who, within the therapeutic area, is performing scientific (complex) clinical data review in close collaboration with the Study Responsible Physicians (SRP) and Study Responsible Scientists (SRS). Tapping into technical and clinical expertise, closely collaborating with the SRP, SRS, Data Management functions and the rest of the study team members when implementing the data management related activities for protocols, with focus on more complex indication and therapy related elements of the study. Reviews all necessary data flows, the Data Management Plans and performs continuous (complex) data review activities on the studies in the assigned program.
- Involved in study related activities from the protocol design stage onwards, providing input into the study specific and/or indication specific data collection tools.
- Reviews (complex) scientific study data, manages CDM and SRS/SRP related queries in eDC system and holds discussions with SRS/SRP. Involvement in other review activities (e.g., Coding, SAE reconciliation) is possible. Leads and/or attends meetings as appropriate.
- Takes a leadership role with SRP/SRS and collaborates with the GDM to establish, align and confirm scientific clinical data review expectations for assigned trial(s).
- With the trial customer, CRO and other functional partners in relation to CDM related activities:
o Reviews content and integration requirements for eCRF and other data collection tools
o Establishes conventions and quality expectations for clinical data.
o Set timelines and follow‐up regularly to ensure delivery of all Clinical Data Management milestones
- Creates the Integrated Review Plan ensuring appropriate quality, scientific content, organization, clarity, accuracy, format, and consistency. Reviews related clinical data management documents. Ensures compliance with regulatory guidelines and documentation requirements.
- Ensures real‐time inspection readiness of all assigned deliverables for the trial; participate in Regulatory Agency inspection and Client internal audits as necessary.
- Plans and tracks applicable CDM deliverables. Ensures CDM deliverables are on time.
- Takes a leadership role in collaborating with the SRS/SRP to ensure that DM and Therapeutic Area trial needs and deliverables are met.
- Identifies and communicates lessons learned, best practices and frequently asked questions at the trial level.
- Identifies and participates in process, system, and tool improvement initiatives within clinical data management.
Therapeutic Area - Oncology, Cardiovascular and Immunology
**Education/Experience**
- BS/BA degree or higher preferably in Health Sciences, or BS/BA degree or higher with professional clinical experience/exposure.
- 5 years Data management experience. Data Management experience preferably including clinical data review or significant experience with clinical data review. Knowledge in medical terminology would be preferable
- Collaboration with Clinical teams.
IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create connections that accelerate the development and commercialization of innovative medical treatments. Everything we do is part of a journey to improve patient outcomes and population health worldwide.
To get there, we seek out diverse talent with curious minds and a relentless commitment to innovation and impact. No matter your role, everyone at IQVIA contributes to our shared goal of helping customers improve the lives of patients everywhere. Thank you for your interest in growing your career with us.
EEO Minorities/Females/Protected Veterans/Disabled