6,584 National Physical Laboratory jobs in the United Kingdom

Job Title : Research Scientist - Protein

Working Location : Bracknell

Rate : £18.41 per hour

Contract Length : 12 months

Start Date : 19th January 2026

We are looking for a hardworking, motivated individual who is quick to learn and apply themselves to join our dynamic, collaborative and industrious protein production team. This is a one-year contract to support the delivery of a critical protein production process. This role offers the opportunity for the successful candidate to gain hands on experience with an array of downstream processing techniques including protein chromatography and membrane filtration methods.

Role profile and expectations:

• Work as part of a protein production team to deliver gram quantities of purified recombinant protein to support one of Syngenta’s critical commercial projects
• Provide hands-on support during this large-scale protein production campaign
• Learn and conduct the necessary analytical methods to validate final outputs meet defined specifications
• Accurately record results to agreed company standards
• Prepare technical reports, present findings within project groups and be an active communicator within the wider Syngenta scientific community
• Work safely and with due care to others ensuring compliance with company HSE policies

Essential education & experience:

• Bachelor’s degree in relevant science e.g. Biology, Biochemistry, Biomedical or other similar disciplines
• Good theoretical understanding of recombinant protein expression
• Good theoretical understanding of chromatography techniques including affinity, ion exchange (IEX), hydrophobic interaction (HIC) and size exclusion (SEC) chromatography
• Strong evidence of troubleshooting and innovative problem solving
• Ability to work independently and as part of a team
• Good communication and planning skills

Desirable experience:

• Master’s degree or 1-2 years’ experience working in a laboratory environment
• 1-2 years lab experience working in any of the core areas highlighted in the above job description
• Experience with data management tools (e.g. Benchling) and data analysis software (e.g. JMP)
• Experience of working with scalable bioprocess technologies e.g. TFF, Hollow fibre

Research Scientist

Oxford

About Exogene

At Exogene, we’re reimagining what’s possible in cancer immunotherapy. Our mission is to engineer T-cell receptor therapies that can precisely and powerfully target advanced solid tumours.

To do this, we’ve built a proprietary lab-in-the-loop platform that merges generative AI, biophysical modelling, and high-throughput TCR screening to rapidly design, test, and optimise TCRs with exceptional affinity and specificity. This convergence of computation and wet-lab experimentation allows us to go from concept to candidate molecules in record time.

We’re developing TCR-based trispecific T cell engagers (TCR-TriTCEs)—a new therapeutic modality designed to overcome the unique challenges of the solid tumour microenvironment. This work spans multiple disciplines, from protein engineering and AI-driven design to in vivo validation and translational development.

We are looking for a dynamic research scientist who will help drive the TCR engineering processes and development. The successful candidate will contribute to in vivo and in vitro validation of TCEs. You’ll get involved in purifying recombinant TCRs to perform high-throughput TCR display methods and deep sequencing.

Responsibilities

• Contribute to in vivo and in vitro validation of TCEs.
• Collaboratively design and characterise TCRs for proprietary and partnered disease targets.
• Conduct a suite of protein science operations, including expression, purification, and biophysical analysis.
• Tackle molecular biology duties: cloning, mutagenesis, DNA isolation, and preparing libraries for deep sequencing.
• Manage tissue culture assignments, spanning from media prep and cell line care to cryopreservation.
• Join forces with founders, R&D, academia, and industrial stakeholders to fulfil ambitious R&D objectives.
• Draft, revise, and oversee repertoire of lab protocols.
• Offer essential lab support and uphold facility upkeep.

Skills and Qualifications

• PhD in Immunology, Cell Biology, Biochemistry, or an alike field, paired with at least 1-2 years of relevant lab experience is required.
• Knowledge of molecular biology protocols, with an emphasis on cloning and PCR is preferred.
• A background in molecular biology, protein expression, purification and biophysical characterisation is preferred.
• Experience in cell and immunological assays (flow cytometry, ELISA etc.) is desired.
• Experience with in vivo and in vitro validation of TCEs (T-cell engagers) in some or all aspects of investigational new drug (IND) approval is desired.
• Experience TCR engineering is desired.
• SOP documentation experience is desired.
• The highest standards in lab precision, record maintenance, and documentation.
• Excellent written and oral communication skills.

Attributes

• Self-starter with sound analytical skills, who values scientific integrity and novelty.
• Collaborative spirit within the lab, open to both giving and receiving actionable feedback.
• Exceptional at diagnosing and overcoming unforeseen technical challenges.
• Adept at juggling and prioritising multiple projects to meet deadlines.
• Versatile and efficient within an interdisciplinary, fast-paced team setup.

What We Offer

• Market-competitive salary and stock option package.
• A generous leave policy: 25 days holiday, public holidays, plus a day off for your birthday!
• Access to fully equipped private lab.
• Flexibility to work from home as project demands allow.
• A supportive, cross-disciplinary team fostering a highly collaborative work environment.

How to apply

Launch your journey with Exogene by submitting your CV and a brief cover letter (maximum 400 words) to m.hasan at exogene.co.uk

Research Scientist | Series A BioTech Startup | £16M+ Raised

Salary: £0,000 – £8 000

Location: London / Hybrid

About the Opportunity

We’re proud to be partnered with a Series A BioTech startup that has raised over £1 million to accelerate the development of next-generation therapeutics through cutting-edge biological and technological innovation.

Backed by leading investors and built by a world-class founding team, this company is entering an exciting phase of growth, expanding its R&D capabilities and scaling breakthrough science into real-world impact.

As a Research Scientist , you’ll join a small, mission-driven team working at the intersection of biology, technology, and data. You’ll take a hands-on role in the lab, designing and executing experiments that drive discovery and shape the company’s R&D pipeline.

Key Responsibilities

• Design, execute, and analyse experiments supporting the company’s core discovery programs.
• Develop, optimise, and validate assays, workflows, and protocols to advance R&D.
• Maintain accurate and organised documentation (ELNs, reports, and presentations).
• Present experimental findings to the leadership and cross-functional teams.
• Collaborate with computational scientists, engineers, and biologists to translate data into insight.
• Stay current on emerging methods and technologies that can accelerate innovation.
• Contribute to building scientific culture, infrastructure, and lab best practices in a growing startup.

About You

Education & Experience

• PhD (or MSc with strong hands-on experience) in Molecular Biology, Biotechnology, Biochemistry, or Life Sciences .
• Postdoctoral or early-stage industry experience preferred — but scientific curiosity, creativity, and rigour matter most.

Technical Skills

• Proficiency in molecular and/or cellular biology techniques.
• Previous experience in a biotech or startup research environment advantageous.

Soft Skills

• Self-starter who thrives in a fast-paced, collaborative setting.
• Excellent communicator and problem-solver with a rigorous scientific mindset.
• Adaptable team player who enjoys contributing across multiple disciplines.
• Driven by innovation and the opportunity to create meaningful impact through science.

Why Join?

Mission-Driven Impact – Contribute to the discovery of breakthrough therapies in a high-growth BioTech.

Research Scientist

Excellerate Bioscience Ltd are currently seeking a highly motivated candidate with an in vitro pharmacology background to join our team. We offer a dynamic team environment, working in partnership with our clients to provide flexible solutions from early-stage target identification to late stage detailed mechanism of action studies, across a range of different drug target classes and disease areas.

Role and Responsibilities

As a Scientist and member of a pharmacology group, you will work as part of a team to develop cell-based, biochemical or pharmacology assays to enable quantitative and rigorous characterization of complex protein-ligand interactions at the molecular level to aid target identification, validation and lead optimisation strategies in support of drug discovery programs across a variety of target classes.

Skills and Experience:

• A BSc / MSc focused on biochemistry, cell biology, pharmacology or related discipline (Essential). Previous industrial or research/academic laboratory experience would be advantageous.
• Familiarity with one or more of the following areas: a) Compound Profiling/in vitro assay development, b) Receptor Pharmacology c) Protein-protein interactions d) Cellular Pharmacology.
• Familiarity with methodologies such as cell culture, cell signalling assays, reporter assays, western blotting, molecular biology.
• Knowledge of working with semi-automated liquid handling systems, preferably working in a 96/384 well format.
• A strong ability to problem-solve and take the lead on project work when needed.
• Excellent interpersonal, collaborative and communication skills.

What we Offer:

Our benefits package includes a competitive salary, pension contribution, plus additional benefits. This position is based at our new state-of-the-art central Nottingham facility.

Only applicants that have eligibility to work in the UK will be considered for the role. Please send your CV with a covering letter outlining why you feel you would be suitable for this role.

Job Type: Full-time

Pay: From £25,000.00 per year

Benefits:

• On-site parking

Ability to commute/relocate:

• Nottingham, NG2 1AE: reliably commute or plan to relocate before starting work (required)

Education:

• Bachelor's (required)

Work authorisation:

• United Kingdom (required)

Work Location: In person

Reference ID: EXCResearchScientist 25

Research Scientist

Oxford

About Exogene

At Exogene, we’re reimagining what’s possible in cancer immunotherapy. Our mission is to engineer T-cell receptor therapies that can precisely and powerfully target advanced solid tumours.

To do this, we’ve built a proprietary lab-in-the-loop platform that merges generative AI, biophysical modelling, and high-throughput TCR screening to rapidly design, test, and optimise TCRs with exceptional affinity and specificity. This convergence of computation and wet-lab experimentation allows us to go from concept to candidate molecules in record time.

We’re developing TCR-based trispecific T cell engagers (TCR-TriTCEs)—a new therapeutic modality designed to overcome the unique challenges of the solid tumour microenvironment. This work spans multiple disciplines, from protein engineering and AI-driven design to in vivo validation and translational development.

We are looking for a dynamic research scientist who will help drive the TCR engineering processes and development. The successful candidate will contribute to in vivo and in vitro validation of TCEs. You’ll get involved in purifying recombinant TCRs to perform high-throughput TCR display methods and deep sequencing.

Responsibilities

• Contribute to in vivo and in vitro validation of TCEs.
• Collaboratively design and characterise TCRs for proprietary and partnered disease targets.
• Conduct a suite of protein science operations, including expression, purification, and biophysical analysis.
• Tackle molecular biology duties: cloning, mutagenesis, DNA isolation, and preparing libraries for deep sequencing.
• Manage tissue culture assignments, spanning from media prep and cell line care to cryopreservation.
• Join forces with founders, R&D, academia, and industrial stakeholders to fulfil ambitious R&D objectives.
• Draft, revise, and oversee repertoire of lab protocols.
• Offer essential lab support and uphold facility upkeep.

Skills and Qualifications

• PhD in Immunology, Cell Biology, Biochemistry, or an alike field, paired with at least 1-2 years of relevant lab experience is required.
• Knowledge of molecular biology protocols, with an emphasis on cloning and PCR is preferred.
• A background in molecular biology, protein expression, purification and biophysical characterisation is preferred.
• Experience in cell and immunological assays (flow cytometry, ELISA etc.) is desired.
• Experience with in vivo and in vitro validation of TCEs (T-cell engagers) in some or all aspects of investigational new drug (IND) approval is desired.
• Experience TCR engineering is desired.
• SOP documentation experience is desired.
• The highest standards in lab precision, record maintenance, and documentation.
• Excellent written and oral communication skills.

Attributes

• Self-starter with sound analytical skills, who values scientific integrity and novelty.
• Collaborative spirit within the lab, open to both giving and receiving actionable feedback.
• Exceptional at diagnosing and overcoming unforeseen technical challenges.
• Adept at juggling and prioritising multiple projects to meet deadlines.
• Versatile and efficient within an interdisciplinary, fast-paced team setup.

What We Offer

• Market-competitive salary and stock option package.
• A generous leave policy: 25 days holiday, public holidays, plus a day off for your birthday!
• Access to fully equipped private lab.
• Flexibility to work from home as project demands allow.
• A supportive, cross-disciplinary team fostering a highly collaborative work environment.

How to apply

Launch your journey with Exogene by submitting your CV and a brief cover letter (maximum 400 words) to m.hasan at exogene.co.uk

Job Title : Research Scientist - Protein

Working Location : Bracknell

Rate : £18.41 per hour

Contract Length : 12 months

Start Date : 19th January 2026

We are looking for a hardworking, motivated individual who is quick to learn and apply themselves to join our dynamic, collaborative and industrious protein production team. This is a one-year contract to support the delivery of a critical protein production process. This role offers the opportunity for the successful candidate to gain hands on experience with an array of downstream processing techniques including protein chromatography and membrane filtration methods.

Role profile and expectations:

• Work as part of a protein production team to deliver gram quantities of purified recombinant protein to support one of Syngenta’s critical commercial projects
• Provide hands-on support during this large-scale protein production campaign
• Learn and conduct the necessary analytical methods to validate final outputs meet defined specifications
• Accurately record results to agreed company standards
• Prepare technical reports, present findings within project groups and be an active communicator within the wider Syngenta scientific community
• Work safely and with due care to others ensuring compliance with company HSE policies

Essential education & experience:

• Bachelor’s degree in relevant science e.g. Biology, Biochemistry, Biomedical or other similar disciplines
• Good theoretical understanding of recombinant protein expression
• Good theoretical understanding of chromatography techniques including affinity, ion exchange (IEX), hydrophobic interaction (HIC) and size exclusion (SEC) chromatography
• Strong evidence of troubleshooting and innovative problem solving
• Ability to work independently and as part of a team
• Good communication and planning skills

Desirable experience:

• Master’s degree or 1-2 years’ experience working in a laboratory environment
• 1-2 years lab experience working in any of the core areas highlighted in the above job description
• Experience with data management tools (e.g. Benchling) and data analysis software (e.g. JMP)
• Experience of working with scalable bioprocess technologies e.g. TFF, Hollow fibre

About Lumirithmic

Lumirithmic, an Imperial College London spin-out, is redefining computer graphics by making Hollywood-grade CGI accessible to everyone. Led by an industry pioneer behind some of the most hyper-realistic VFX ever created, we're building cutting-edge technology that empowers studios in VFX, gaming, and tech to deliver world-class content at a fraction of today's cost.

We are looking for a PhD-level researcher/engineer with expertise in facial appearance capture, skin modelling, and real-time rendering. You will join our world-class team of scientists and engineers, working on cutting-edge methods to capture and render faces with unparalleled accuracy and realism.

In this role, you will not only design novel algorithms and optimise pipelines for mobile and desktop but also take an active role in managing and communicating across client projects. You will ensure research outcomes are translated into production-ready technology while maintaining clear, effective collaboration with both internal teams and external partners — directly impacting Lumirithmic's core products.

Key Responsibilities

• Research and develop advanced algorithms for skin reflectance modelling, facial deformation, and material appearance capture.
• Build and optimise capture-to-animation pipelines for mobile and desktop platforms.
• Develop GPU-accelerated rendering and shader implementations for realistic faces.
• Manage client-facing projects and communicate technical progress, results, and challenges clearly to stakeholders.
• Collaborate with internal teams on patents, publications, and prototypes.
• Translate research into production features integrated into Lumirithmic products.

Required Qualifications

·   PhD in Computer Graphics, Computer Vision, Computational Imaging, or related fields.

·   Strong background in facial appearance, reflectance, or skin modelling.

·   Expertise in C++ and GPU programming (CUDA, GLSL, HLSL, Vulkan, or similar).

·   Strong knowledge of 3D geometry, linear algebra, and numerical optimisation.

·   Experience with deep learning frameworks (PyTorch, TensorFlow) for graphics/vision.

·   Proven track record via publications, patents, or impactful projects.

Preferred Qualifications

·   Hands-on experience with spectral or multispectral reflectance measurement.

·   Knowledge of neural rendering (e.g., NeRF, NeuS, diffusion-based methods).

·   Familiarity with DCC tools and pipelines (Maya, Blender, Houdini).

·   Contributions to open-source graphics/vision projects.

·   Prior industry collaboration or technology transfer experience.

What we offer

·   A chance to shape the future of digital humans.

·   Work alongside leading researchers in computer graphics and vision.

·   Competitive salary, benefits, and research resources.

·   Support for publishing, patents, and conference participation.

• Impactful projects spanning film, gaming, AR/VR, and digital cosmetics.

How to Apply

To streamline your application, please follow this two-step process:

1. Answer Screening Questions:
   Complete our short screening form here to fast-track your application:

2. Submit your CV:
   Email your CV and a brief cover letter directly to

3. Please note that both steps are required for your application to be considered.

Origin Sciences is a start-up biotechnology company based in Granta Park, south of Cambridge. We develop our own innovative medical devices, which we use in clinical trials to collect a biobank of mucus-based biospecimens. This biobank provides a valuable source of clinical material that is used for fundamental research, method/technology development and the creation of diagnostic assays.

Currently, our diagnostic development programs primary focus is the detection of Colorectal Cancer (CRC) and pre-cancerous lesions. Our motivation is to streamline the colorectal cancer detection pathway, enabling healthcare systems to focus on those patients with serious pathologies, ultimately reducing waiting times, enabling earlier detection, and minimising unnecessary investigations performed on healthy patients.

The role:
Origin Sciences is a medical technology company that develops innovative devices and IVD tests to aid in the detection and diagnosis of gastrointestinal diseases. Our current focus is on the diagnosis of colorectal cancer (CRC). The Senior Research Scientist is an experienced laboratory scientist in the field of life sciences, with a proven track record in molecular diagnostics, biomarker validation, PCR-based assays, NGS technologies and cancer genetics.

Requirements
The Senior Research Scientist will support and lead laboratory processes and developments, with a particular focus on molecular biology and Next Generation Sequencing (NGS), as such a proven track record of PCR and NGS is essential. An honours degree in biological sciences, biomedical sciences, biochemistry or equivalent is required in addition to; practical knowledge of biomarker discovery, assay optimization, immunological techniques and working with clinical samples. Education to MSc/PhD level would be preferred, but extensive relevant laboratory experience is also acceptable for the role.

This position is part of the Development Team working to deliver a molecular diagnostics assay with associated NGS technologies. The Senior Research Scientist will work to develop and optimise laboratory processes and participate in the design and implementation of research and development programs. This position requires high attention to detail, the ability to critically assess data, to work to SOPs and a strong focus on quality and reproducibility. Skilled project and time management and the capacity to work well individually or as part of a team are essential.

Additionally, the Senior Scientist will have the opportunity to work in the commercial area of the scientific process; scoping technologies, providers, forging commercial alliances and participating in the delivery of appropriate documentation for notified body submission.

The specific duties of a Senior Research Scientist are:

• Perform nucleic acid extraction and store biobank clinical samples
• Lead the development and testing of new detection technologies
• Liaise with the clinical trial teams to coordinate clinical sample deliveries
• Complete stability, performance, and validation assays, followed by analysis and reporting
• Design, develop and test assays for use in product development
• Work towards the goals of collaborative projects with external partners
• Be accountable for the time, cost, and quality of agreed deliverables
• Provide updates on the progress, risks, and opportunities of the agreed deliverables
• Working in a regulated environment, e.g. Good Laboratory Practice or other GxP
• Assessments of related diagnostic technologies and products
• Contribute to scientific communication, peer reviewed publications, leaflets and poster
• To ensure projects are carried out in accordance with Origin's Quality Systems and Regulatory Standards

We are seeking a
Field Research Scientist
to join a global research team focused on advancing biodiversity science through innovative fieldwork and international collaboration. This position has two main components: managing international research partnerships and leading field expeditions to biodiversity hotspots worldwide.

Both activities support the collection of microbial diversity data that contributes to one of the world's largest and fastest-growing databases of protein sequences.

This ethically sourced database underpins advanced AI foundation models designed to build a "digital twin" of Earth's biodiversity. Because of our strong emphasis on traceable, responsible data sourcing, part of this role will also focus on coordinating the knowledge-sharing aspects of our biodiversity partnerships—from data collection through to potential commercialization.

The position combines field-based molecular biology work (including DNA extraction and processing) with collaboration management. You'll work closely with experts across disciplines including data science, biotechnology, and biodiversity research, within a dynamic and passionate international team based in London and Boston.

Roles and Responsibilities

Collaboration Project Management

• Work with international research groups, NGOs, academic institutions, and private partners to plan and execute environmental sampling projects that generate extracted DNA for research databases and provide valuable insights for biodiversity partners (e.g., for conservation or academic purposes).
• Deliver environmental sampling and DNA extraction training to global biodiversity partners.
• Manage and apply for research and sampling permits, collaborating with governing bodies, national parks, and conservation areas to expand global sampling access.
• Coordinate DNA biobanking activities in London to support sequencing workflows and production teams.

Field Expeditions

• Plan and lead scientific expeditions to national parks, private lands, and conservation areas where sampling permits have been obtained.
• Expeditions may range from short day trips to multi-week fieldwork, including:
• Coordinating logistics for travel, accommodation, and equipment.
• Conducting fieldwork safely in a variety of environments (hiking, boating, driving, etc.).
• Collecting samples and metadata accurately and consistently.
• Managing expedition documentation (customs paperwork, packing lists, equipment tracking).
• Performing in-situ DNA extraction using portable laboratory equipment.

Key Skills and Experience

Preferred Background

• Degree or equivalent experience in Environmental Science, Biodiversity, or related Life Sciences (e.g., ecology, molecular biology, climate science, or geology).

Interpersonal Skills

• Strong communication skills, with the ability to engage clearly and professionally with internal and external stakeholders.
• Proven ability to manage multiple concurrent projects and deadlines.
• A strong motivation to contribute to global biodiversity and conservation research.

Field Skills

• Experience safely operating scientific and technical equipment in the field and in remote environments.
• Proven ability to plan and execute sampling fieldwork, including logistics, safety, and compliance.
• Knowledge of expedition planning (customs procedures, packing, first aid, lone working protocols).
• Experience leading and coordinating field teams, ensuring safety, efficiency, and data integrity.
• Skilled in data recording, management, and quality control for post-field analysis.
• Adaptability and troubleshooting skills for unpredictable field conditions.

Other Desirable Experience

• General molecular biology or microbiology skills (e.g., DNA extraction, sequencing preparation, sample processing).
• Familiarity with lab administration, biosecurity, and permitting processes.

Working Style

• Location:
  Office-based in London, UK (non-remote).
• Travel:
  Regular international travel required (approximately 2 weeks every 2 months).