49 Organic Synthesis jobs in the United Kingdom
Senior Research Scientist - Organic Synthesis
Posted 1 day ago
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Job Description
Key Responsibilities:
- Design and execute multi-step synthetic routes for novel small molecules with potential therapeutic applications.
- Optimize existing synthetic procedures to improve yield, purity, and scalability.
- Characterize synthesized compounds using various analytical techniques, including NMR, Mass Spectrometry, and HPLC.
- Collaborate with medicinal chemists and biologists to support drug discovery programs.
- Troubleshoot synthetic challenges and develop innovative solutions.
- Maintain meticulous laboratory notebooks and document all experimental procedures and results.
- Stay current with the latest advancements in synthetic organic chemistry and related fields.
- Mentor and guide junior research scientists and technicians in the laboratory.
- Contribute to intellectual property generation through invention disclosures and patent applications.
- Ensure compliance with all safety regulations and laboratory best practices.
Qualifications:
- Ph.D. in Organic Chemistry or a closely related field.
- Minimum of 5 years of postdoctoral or industry experience in synthetic organic chemistry.
- Demonstrated expertise in modern synthetic methodologies, including asymmetric synthesis and organometallic chemistry.
- Strong proficiency in spectroscopic characterization techniques (NMR, MS, IR).
- Experience with process development and scale-up is highly desirable.
- Excellent problem-solving skills and a creative approach to synthetic challenges.
- Strong written and verbal communication skills.
- Ability to work independently and as part of a collaborative research team.
- Proficiency in literature searching and data analysis.
- Commitment to laboratory safety and quality standards.
This is an excellent opportunity for a skilled synthetic chemist to contribute to impactful pharmaceutical research. The role is based in the region of Leicester, Leicestershire, UK .
Lead Research Chemist - Organic Synthesis
Posted 2 days ago
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Job Description
Key Responsibilities:
- Lead and manage organic synthesis research projects.
- Design and execute novel synthetic routes for complex molecules.
- Troubleshoot and optimize synthetic procedures.
- Characterize newly synthesized compounds using advanced analytical techniques.
- Supervise and mentor junior research chemists.
- Contribute to scientific publications and patent applications.
- Collaborate with cross-functional teams to meet project objectives.
- Ensure adherence to laboratory safety protocols and best practices.
- PhD in Organic Chemistry or a related field.
- Minimum 7 years of relevant research experience, with demonstrated leadership.
- Extensive expertise in modern organic synthesis methodologies.
- Proficiency with analytical techniques (NMR, MS, HPLC, etc.).
- Proven ability to design and execute complex synthetic projects.
- Strong problem-solving and critical thinking skills.
- Excellent written and verbal communication abilities.
- Track record of scientific publications or patents.
Senior Research Scientist - Organic Synthesis
Posted 3 days ago
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Job Description
Key Responsibilities:
- Design and synthesize novel organic molecules using a variety of synthetic methodologies.
- Develop and optimize multi-step synthetic routes for target compounds.
- Characterize synthesized compounds using advanced spectroscopic and analytical techniques (e.g., NMR, MS, HPLC, GC).
- Troubleshoot synthetic challenges and develop innovative solutions.
- Perform literature searches and stay current with the latest advancements in organic synthesis.
- Collaborate with cross-functional teams to advance research projects.
- Prepare detailed research reports, scientific presentations, and contribute to patent applications.
- Mentor and guide junior scientists and technicians in the laboratory.
- Ensure safe laboratory practices and compliance with environmental health and safety regulations.
- Contribute to the development of scalable and cost-effective chemical processes.
- Ph.D. in Organic Chemistry or a closely related field.
- Minimum of 5 years of relevant industrial or post-doctoral research experience in organic synthesis.
- Demonstrated expertise in modern synthetic organic chemistry, including asymmetric synthesis, catalysis, and heterocycle chemistry.
- Proficiency in NMR, MS, IR, HPLC, and GC techniques for structural elucidation and purity assessment.
- Strong understanding of reaction mechanisms and kinetics.
- Excellent problem-solving abilities and critical thinking skills.
- Effective written and verbal communication skills, with the ability to present complex scientific information.
- Proven ability to manage multiple projects and prioritize effectively.
- Experience with computational chemistry tools is a plus.
- Ability to work independently and collaboratively in a research team environment.
Senior Research Scientist - Organic Synthesis
Posted 3 days ago
Job Viewed
Job Description
Key Responsibilities:
- Design and execute synthetic routes for novel small molecules, including complex heterocyclic compounds and natural product analogues.
- Optimize reaction conditions to improve yield, purity, and scalability.
- Purify synthesized compounds using various chromatographic techniques (e.g., column chromatography, HPLC).
- Characterize compounds using analytical methods such as NMR, Mass Spectrometry, and IR spectroscopy.
- Troubleshoot synthetic challenges and proactively seek solutions.
- Maintain detailed and accurate laboratory notebooks and research records.
- Collaborate effectively with medicinal chemists, biologists, and other research staff.
- Evaluate new synthetic methodologies and technologies for potential application.
- Contribute to the preparation of research reports, publications, and patent applications.
- Manage laboratory inventory and ensure compliance with safety regulations.
- Participate in team meetings, presenting research progress and discussing experimental strategies.
Required Qualifications:
- PhD in Organic Chemistry or a closely related field.
- Minimum of 5 years of post-doctoral or industry experience in synthetic organic chemistry.
- Demonstrated expertise in modern organic synthesis techniques, including asymmetric synthesis, organometallic chemistry, and catalysis.
- Strong proficiency in spectroscopic characterization techniques (NMR, MS, IR).
- Experience with purification techniques like chromatography (flash, HPLC).
- Excellent problem-solving skills and a strong ability to critically analyze experimental data.
- Proven track record of successfully synthesizing complex target molecules.
- Ability to work independently and as part of a multidisciplinary research team.
- Strong written and verbal communication skills.
- Experience with computational chemistry tools is a plus.
- Familiarity with process chemistry principles for scale-up is advantageous.
This role requires a commitment to hybrid working, with a blend of on-site laboratory work in **Brighton, East Sussex, UK**, and opportunities for remote data analysis and report writing.
Senior Research Scientist - Organic Synthesis
Posted 10 days ago
Job Viewed
Job Description
Responsibilities:
- Design and execute multi-step organic syntheses to produce target molecules with high purity and yield.
- Develop and optimize existing synthetic procedures, improving efficiency and reducing costs.
- Characterize synthesized compounds using a range of analytical techniques (NMR, MS, HPLC, GC, IR).
- Interpret complex analytical data and troubleshoot synthetic challenges.
- Conduct literature searches to identify relevant synthetic methodologies and stay updated on scientific advancements.
- Collaborate with interdisciplinary teams, including analytical chemists, process engineers, and formulation scientists.
- Prepare detailed technical reports, research summaries, and presentations.
- Maintain accurate and up-to-date laboratory notebooks and records in compliance with company standards.
- Contribute to the intellectual property strategy through the identification of novel compounds and processes.
- Mentor junior research scientists and provide technical guidance.
- Ensure adherence to all laboratory safety protocols and procedures.
- Ph.D. in Organic Chemistry or a closely related field from a reputable institution.
- Minimum of 5 years of post-doctoral or industrial research experience focused on organic synthesis.
- Demonstrated expertise in modern synthetic organic chemistry techniques and reaction mechanisms.
- Extensive hands-on experience with a wide array of synthetic transformations and purification methods (e.g., chromatography, crystallization).
- Proficiency in spectroscopic and chromatographic analytical techniques (e.g., 1D/2D NMR, LC-MS, GC-MS, HPLC).
- Proven ability to design synthetic routes and troubleshoot complex chemical problems.
- Excellent written and verbal communication skills, with the ability to present complex scientific information clearly.
- Strong collaborative skills and experience working effectively in a team environment.
- Proficiency in using chemical drawing software (e.g., ChemDraw) and literature databases (e.g., SciFinder, Reaxys).
- Experience in medicinal chemistry, process chemistry, or materials science is a plus.
Senior Research Scientist - Organic Synthesis
Posted 10 days ago
Job Viewed
Job Description
Location: Fully remote within the UK, with research connections to Edinburgh, Scotland, UK .
Responsibilities:
- Design and execute complex multi-step organic syntheses.
- Develop novel synthetic methodologies and pathways.
- Synthesize target molecules for research and development purposes.
- Characterize synthesized compounds using analytical techniques (NMR, MS, HPLC, etc.).
- Optimize reaction conditions and purification procedures.
- Troubleshoot synthetic challenges and devise solutions.
- Collaborate with cross-functional research teams.
- Maintain detailed laboratory notebooks and prepare technical reports.
- Stay current with advancements in synthetic organic chemistry.
- PhD in Organic Chemistry or a closely related field.
- Significant experience in synthetic organic chemistry, including multi-step synthesis.
- Proficiency in modern synthetic techniques and reaction mechanisms.
- Expertise in compound characterization using spectroscopic and chromatographic methods.
- Strong analytical and problem-solving abilities.
- Excellent laboratory skills and meticulous documentation habits.
- Ability to work independently and manage project timelines effectively in a remote setting.
- Strong communication and collaboration skills.
Advanced Research Scientist - Organic Synthesis
Posted 20 days ago
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Job Description
Key Responsibilities:
- Design, synthesize, and purify novel organic molecules using a wide range of synthetic methodologies.
- Develop and optimize synthetic routes for target compounds, with a focus on efficiency, scalability, and safety.
- Characterize synthesized compounds using advanced analytical techniques, including NMR, Mass Spectrometry, HPLC, and GC.
- Conduct literature searches and stay abreast of the latest advancements in synthetic organic chemistry and medicinal chemistry.
- Troubleshoot synthetic challenges and develop innovative solutions to overcome experimental hurdles.
- Collaborate effectively with medicinal chemists, biologists, and other research scientists to advance drug discovery programs.
- Maintain detailed and accurate laboratory notebooks and prepare technical reports and presentations.
- Contribute to the preparation of patent applications and scientific publications.
- Ensure compliance with laboratory safety protocols and procedures.
- Mentor and guide junior research assistants or post-doctoral fellows as needed.
- PhD in Organic Chemistry or a closely related field.
- Post-doctoral experience or equivalent industry experience in synthetic organic chemistry is highly desirable.
- Demonstrated expertise in multi-step synthesis, retrosynthesis, and modern synthetic techniques.
- Proficiency in spectroscopic and chromatographic techniques for compound characterization.
- Strong understanding of reaction mechanisms and stereochemistry.
- Excellent problem-solving skills and a creative approach to synthetic challenges.
- Ability to work independently and as part of a collaborative research team.
- Strong written and verbal communication skills.
- Familiarity with drug discovery processes and medicinal chemistry is a plus.
- Experience with purification techniques such as chromatography (flash, HPLC) and crystallization.
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Principal Research Scientist - Organic Synthesis
Posted 20 days ago
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Job Description
As a Principal Research Scientist, you will be responsible for designing complex synthetic routes, executing challenging multi-step syntheses, and characterizing novel molecules. You will leverage your extensive expertise in modern organic chemistry to solve intricate synthetic problems and drive projects from early-stage discovery through to pre-clinical development. This role requires a deep understanding of reaction mechanisms, stereochemistry, and the application of various synthetic methodologies. You will mentor junior scientists, present your findings to internal teams and stakeholders, and contribute to the strategic direction of research programs.
Key responsibilities:
- Lead the design and execution of complex synthetic strategies for novel drug candidates.
- Perform challenging multi-step organic syntheses and purification of target compounds.
- Characterize synthesized compounds using advanced analytical techniques (e.g., NMR, Mass Spectrometry, HPLC).
- Develop and troubleshoot synthetic routes to improve efficiency, yield, and purity.
- Stay abreast of the latest advancements in synthetic organic chemistry and apply them to research challenges.
- Mentor and guide junior research scientists in synthetic methodologies and project execution.
- Collaborate effectively with medicinal chemists, biologists, and other research team members.
- Prepare comprehensive research reports, presentations, and contribute to scientific publications and patent filings.
- Contribute to strategic planning and target identification for new research programs.
- Ensure rigorous adherence to laboratory safety protocols and data integrity standards.
Essential qualifications and experience:
- PhD in Organic Chemistry or a related field.
- A minimum of 8 years of post-doctoral or industry experience in synthetic organic chemistry, preferably within the pharmaceutical or biotech sector.
- Demonstrated track record of successfully designing and executing complex organic syntheses.
- Expertise in a wide range of synthetic organic reactions and techniques.
- Proficiency in modern analytical techniques for compound characterization.
- Strong understanding of medicinal chemistry principles and drug discovery processes.
- Excellent problem-solving skills and creativity in synthetic design.
- Outstanding written and verbal communication skills.
- Proven ability to lead research projects and mentor team members.
- Ability to work independently and manage multiple research priorities in a remote environment.
This is a unique opportunity for a highly skilled organic chemist to contribute to impactful drug discovery in a flexible, remote setting. If you are passionate about synthetic chemistry and driven by scientific innovation, we encourage you to apply.
Senior Chemistry Lecturer - Organic Synthesis Focus
Posted 20 days ago
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Job Description
Key Responsibilities:
- Develop and deliver engaging undergraduate and postgraduate lectures and laboratory courses in Organic Chemistry and related fields.
- Design and implement innovative teaching methodologies and assessment strategies to enhance student learning outcomes.
- Supervise student research projects, including dissertations and theses.
- Contribute to curriculum development and course revisions to ensure alignment with current scientific advancements and industry needs.
- Mentor and advise students on academic and career pathways.
- Conduct and publish high-quality research in the field of organic synthesis or a related area.
- Actively participate in departmental meetings, committees, and academic initiatives.
- Seek opportunities for external funding and collaborative research projects.
- Contribute to the broader academic life of the university through outreach activities and public engagement.
- Maintain up-to-date knowledge of developments in organic chemistry and higher education pedagogy.
- PhD in Organic Chemistry or a closely related discipline.
- A strong publication record in peer-reviewed journals, demonstrating expertise in organic synthesis.
- Minimum of 3-5 years of teaching experience at the university level, with a proven ability to engage and inspire students.
- Demonstrated excellence in lecturing, curriculum design, and student supervision.
- Excellent communication, presentation, and interpersonal skills.
- A commitment to pedagogical research and evidence-based teaching practices.
- Ability to work independently and collaboratively within a team environment.
- Experience in securing research grants is advantageous.
- This position is structured as a fully remote role, allowing for flexibility in work location, though occasional on-site presence for specific academic events or meetings may be requested.
Senior R&D Chemist (Organic Synthesis)
Posted 7 days ago
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Job Description
Key responsibilities include:
- Designing and executing multi-step synthetic routes for novel organic molecules and advanced materials.
- Developing and optimizing synthetic procedures for improved yield, purity, and efficiency.
- Performing characterization of synthesized compounds using spectroscopic techniques (NMR, MS, IR, UV-Vis) and chromatographic methods (HPLC, GC).
- Troubleshooting challenging synthetic problems and developing innovative solutions.
- Collaborating with analytical chemists to ensure rigorous characterization and quality control of products.
- Conducting literature searches and patent landscape analyses to identify new synthetic strategies and research opportunities.
- Mentoring junior chemists and providing technical guidance on synthetic methodologies.
- Working with process chemists and engineers to evaluate the scalability of synthetic routes.
- Ensuring all laboratory activities are conducted safely and in compliance with relevant regulations and company policies.
- Preparing detailed technical reports, presentations, and scientific publications.
- Managing laboratory resources and maintaining a well-organized and equipped laboratory environment.
- Staying up-to-date with the latest advancements in synthetic organic chemistry and related fields.