194 Parexel jobs in the United Kingdom
Statistical Genetics Lead - Clinical Trials
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Your new company
A leading biotech company, with a well-established presence in multiple therapy areas is looking to hire a Lead Statistical Genetics Scientist to support the further development of their products.They have a track record of innovation and a highly collaborative, cross-functional work environment.You would be joining an established team with significant expertise within genetics and genomics research, partnering with colleagues in bioinformatics, clinical development and R&D.
Your new role
You will be responsible for the Statistical Genetics work required to support an asset being taken through late-stage trials.
Major responsibilities will include (but are not limited to):
- Formulate a genomics strategy for advancing late-stage therapeutic programs
- Lead generation of WGS and other omics data within clinical trials
- Conduct research within diverse teams, ensuring high levels of scientific rigour are applied
- Supervise a team providing data-driven insights to address critical business needs and technical questions
- Present findings to internal and external stakeholders, shaping decision-making processes
- Draft study synopses, protocols, reports, and regulatory documents to support clinical development
- Create and implement a publication strategy, including overseeing manuscript preparation
This role is based out of London with significant scope for home/remote working.
What you'll need to succeed
As well as strong communication and organisational skills, candidates should have:
- A PhD (or equivalent experience) in statistical genetics, bioinformatics or a related discipline
- Deep expertise in statistical genetics, especially in developing and applying polygenic risk scores to patient populations
- Demonstrated success in leading research projects independently, with a strong preference for those involving clinical trial data
- A good publication record, or demonstrable experience of presenting complex scientific results/ideas to non-technical stakeholders
- Ideally hands-on experience within the pharmaceutical, biotech, CRO or similar industry as a Statistical Geneticist
- A background of collaborating with partners to pinpoint and address critical scientific questions
What you'll get in return
A generous daily rate and the opportunity to make a significant impact on the company's portfolio as they advance an asset towards the market, working with a high-performing team.
What you need to do now
If you're interested in this role, click 'apply now' to forward an up-to-date copy of your CV, or call us now.
If this job isn't quite right for you but you are looking for a new position within bioinformatics or genetics, please contact us for a confidential discussion on your career.
Keywords: Statistical, Genetics, Genomic, Data, Clinical, Trial, WGS, Omics, Pharmaceutical, Industry, Biotech, Research, Development, PRS, Polygenic, Scores, Analysis, Patient, Stratification, Selection, Bioinformatics, Project, Leader, Principal, Cross-functional, Teams, Stakeholder, Scientific, Questions, Samples, Generation, Strategy, Expansion, Programme, Communication, Publications, Presentations, Leadership
Pharmaceutical Project Manager - Clinical Trials
Posted 4 days ago
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You will manage all phases of clinical trials, from initial protocol development and site selection to data analysis and final reporting. This involves developing detailed project plans, managing budgets, identifying and mitigating risks, and coordinating with cross-functional teams including clinical research associates (CRAs), data managers, statisticians, and medical writers. Building and maintaining strong relationships with investigators, ethics committees, and regulatory authorities will be paramount. You will also oversee vendor management, ensuring timely delivery of services.
Key Requirements:
- Bachelor's or Master's degree in a life science, pharmacy, or related discipline.
- Minimum of 5 years of experience in clinical trial management within the pharmaceutical or biotech industry.
- Proven track record of successfully managing Phase I, II, or III clinical trials.
- In-depth knowledge of GCP, ICH guidelines, and regulatory submission processes.
- Experience with clinical trial management systems (CTMS) and electronic data capture (EDC) systems.
- Excellent leadership, communication, and interpersonal skills.
- Ability to manage budgets and timelines effectively.
- This role requires your presence at our Edinburgh office for effective collaboration and operational oversight.
Statistical Genetics Lead - Clinical Trials
Posted 1 day ago
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Your new company
A leading biotech company, with a well-established presence in multiple therapy areas is looking to hire a Lead Statistical Genetics Scientist to support the further development of their products.They have a track record of innovation and a highly collaborative, cross-functional work environment.You would be joining an established team with significant expertise within genetics an.
Manager, Global Submission Management, Clinical Trials
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Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .
**Position Purpose**
The Submission Manager, Clinical Trials manages and coordinates the timely, compliant, and accurate delivery of the core submission documents and dossiers to Bristol Myers Squibb (BMS) HA/EC Applicants and CRO. The Submission Manager also participates in the preparation of the CTIS for CT under the EU Regulation
**Key Responsibilities**
+ Prepare and distribute the global Clinical Trial Application dossier and subsequent substantial amendments to country applicants and CROs for submission to ECs and HAs.
+ Prepare the data required in CTIS for global Clinical Trial Application dossiers and their subsequent substantial modifications.
+ Manage the CT Amendment log considering the EU Regulation and determine windows of opportunity for submissions, escalate within BMS
+ Provide support to the Submission Senior Manager/collaborate with the Submission Specialist in CTA preparation activities for initial filings and start up activities, protocol amendments, end of trials and CSR distributions.
+ Ensure consistency of the Clinical Trial application across projects, studies and countries.
+ Lead Program/Study level CTA Tracking Meetings, in preparation of the CTA dossier, ensuring timelines and dossier quality are managed according to expectations.
+ Liaise with country offices and central team (Clinical Supply Operations, Operation Leads, Protocol Managers, Medical Monitor, Safety, Quality Person) to ensure that Clinical trial application activities are in compliance with study timelines, BMS SOPs, worldwide regulatory guidelines and regulations.
+ Comply with the use and maintenance of the available planning & tracking tools (e.g. Veeva - HA submission and approval Tracking system) to generate reports and track the CTA content and associated dates.
+ Escalate to study teams and GSM-CT senior roles observed trends and issues that may impact timely and successful study approval and execution
+ Contribute to the Global Country Requirements Repository by collecting and sharing additional country requirements.
+ Support initiatives for innovation and simplification in the processes to improve the support to the study teams and GSM-CT.
+ Coordinate updates within a Program.
+ Support continuous improvement and compliance initiatives
+ Utilizes technology effectively to support the clinical trial application submission process. Proficient use of CTMS, Tracking systems, Excel trackers, to generate reports and track the CTAp content and associated dates
+ Contributes to other requirements as appropriate to allow proper functioning of the GSM-CT.
+ Support implementation of the EU CT REG Portal from Feb 2022.
+ Provide training/mentoring to the GSM-CT newcomers
**Required Qualifications & Experience**
+ BA/BS degree in a science or technology field, preferred
+ Extensive relevant regulatory submissions experience
**Key Competencies**
+ Expert knowledge of Regulatory Submissions and package content for non-US clinical trial applications to health authorities.
+ Assists in the development of short- and long-term goals for own workgroup in alignment with those of GSM and the R&D umbrella.
+ Resolves problems/difficulties with the assistance of senior team members.
+ Supports other functions as appropriate.
+ Independently facilitate compound/study team meetings.
+ Works Independently and collaborates with other functional areas.
#LI-Hybrid
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
**Uniquely Interesting Work, Life-changing Careers**
With a single vision as inspiring as Transforming patients' lives through science , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
**On-site Protocol**
BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to . Visit careers.bms.com/ ( eeo-accessibility to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
Bristol Myers Squibb is Disability Confident - Employer
A UK Government scheme
**Company:** Bristol-Myers Squibb
**Req Number:** R1594122
**Updated:** 2025-08-24 03:30:54.496 UTC
**Location:** Uxbridge-GB
Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.
Senior Consultant- Life Sciences- Clinical Trials - London
Posted today
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At Capgemini Invent, we believe difference drives change. As inventive transformation consultants, we blend our strategic, creative and scientific capabilities, collaborating closely with clients to deliver cutting-edge solutions. Join us to drive transformation tailored to our client's challenges of today and tomorrow. Informed and validated by science and data. Superpowered by creativity and design. All underpinned by technology created with purpose.
YOUR ROLE
In this role you will play a key role in:
Support the growth of early R&D and clinical areas within the Life Sciences and Pharma sector to expand current areas of work and projects within the team
Lead projects within the early R&D and clinical space for life sciences and pharmaceutical clients, delivering data-driven insights and strategic recommendations to enhance client outcomes
Develop and oversee the execution of go-to-market strategies and offers for supporting clients on emerging therapies, ensuring alignment with scientific validation and regulatory requirements.
Keep abreast of the latest industry trends, regulatory changes, and advancements in AI and GenAI technologies in the drug discovery space to maintain a competitive edge and continue providing meaningful support to clients
Mentor and lead a team of consultants and researchers, providing guidance and support in complex R&D projects and encouraging continuous professional growth.
As part of your role you will also have the opportunity to contribute to the business and your own personal growth, through activities that form part of the following categories:
Business Development – Leading/contributing to proposals, RFPs, bids, proposition development, client pitch contribution, client hosting at events.
Internal contribution – Campaign development, internal think-tanks, whitepapers, practice development (operations, recruitment, team events & activities), offering development.
Learning & development – Training to support your career development and the skills demand within the company, certifications etc.
YOUR PROFILE
To be successful you’ll bring strong consulting and personal skills with the ability to overcome internal barriers with drive, determination and influencing skills. You’ll have a natural ability to work in mixed teams of colleagues and senior executives and possess outstanding communication and interpersonal skills. You’ll understand the importance of developing a collaborative style and of having fun in the work we do.
Master’s or PhD in Life Sciences, Data Science, Bioinformatics, or related fields
Good understanding of Clinical R&D Phase processes, methodologies and innovation/technological advancement around them is desirable
Minimum of 4 years of consulting experience in the life sciences and pharmaceutical industry, with a proven track record of leading successful projects
Strong analytical and problem-solving skills, with the ability to translate complex data into actionable insights
Excellent interpersonal and communication skills, capable of effectively engaging and influencing senior stakeholders and clients
NEED TO KNOW
At Capgemini we don’t just believe in inclusion, we actively go out to making it a working reality. Driven by our core values and Inclusive Futures for All campaign, we build environments where you can bring you whole self to work.
We aim to build an environment where employees can enjoy a positive work-life balance. We embed hybrid working in all that we do and make flexible working arrangements the day-to-day reality for our people. All UK employees are eligible to request flexible working arrangements.
Employee wellbeing is vitally important to us as an organisation. We see a healthy and happy workforce a critical component for us to achieve our organisational ambitions. To help support wellbeing we have trained ‘Mental Health Champions’ across each of our business areas. We have also invested in wellbeing apps such as Thrive and Peppy.
CSR
We’re also focused on using tech to have a positive social impact. So, we’re working to reduce our own carbon footprint and improve everyone’s access to a digital world. It’s something we’re really serious about. In fact, we were even named as one of the world’s most ethical companies by the Ethisphere Institute for the 10th year. When you join Capgemini, you’ll join a team that does the right thing.
Whilst you will have London, Manchester or Glasgow as an office base location, you must be fully flexible in terms of assignment location, as these roles may involve periods of time away from home at short notice.
We offer a remuneration package which includes flexible benefits options for you to choose to suit your own personal circumstances and a variable element dependent grade and on company and personal performance.
ABOUT CAPGEMINI
Capgemini is a global business and technology transformation partner, helping organizations to accelerate their dual transition to a digital and sustainable world, while creating tangible impact for enterprises and society. It is a responsible and diverse group of 340,000 team members in more than 50 countries. With its strong over 55-year heritage, Capgemini is trusted by its clients to unlock the value of technology to address the entire breadth of their business needs. It delivers end-to-end services and solutions leveraging strengths from strategy and design to engineering, all fueled by its market leading capabilities in AI, cloud and data, combined with its deep industry expertise and partner ecosystem. The Group reported 2023 global revenues of €22.5 billion.
Clinical Research Associate - Pharmaceutical Trials
Posted 3 days ago
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- Monitoring clinical trial sites to ensure adherence to protocols, SOPs, and regulatory guidelines (e.g., ICH-GCP).
- Conducting site initiation visits, interim monitoring visits, and close-out visits.
- Verifying the accuracy, completeness, and consistency of source documentation and case report forms (CRFs).
- Ensuring the safety and well-being of study participants.
- Managing site communications and providing support to investigators and study staff.
- Identifying and resolving site-level issues and escalating them as needed.
- Ensuring timely data entry and query resolution.
- Reviewing study documents, including investigator site files and regulatory binders.
- Maintaining effective working relationships with clinical sites and internal project teams.
- Participating in team meetings and contributing to the overall success of the clinical trial.
Lead Clinical Research Associate - Oncology Trials
Posted 3 days ago
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Key Responsibilities:
- Conducting site initiation, routine, and close-out monitoring visits.
- Ensuring compliance with study protocols, SOPs, and regulatory requirements (e.g., ICH-GCP).
- Verifying data accuracy and completeness through source data verification (SDV).
- Managing study timelines and site performance metrics.
- Building and maintaining effective relationships with investigative sites.
- Mentoring and providing guidance to junior CRAs.
- Identifying and escalating potential study risks and issues.
- Preparing and presenting monitoring reports.
- Collaborating with internal study teams, including project managers and data managers.
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Clinical Research Associate (CRA) - Pharmaceutical Trials
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Clinical Research Associate (CRA), Oncology Trials
Posted 2 days ago
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Key Responsibilities:
- Performing site selection, initiation, monitoring, and close-out visits in accordance with protocol and regulatory requirements.
- Ensuring the accuracy, completeness, and quality of clinical data through source data verification.
- Training and mentoring investigators and site staff on study procedures and regulatory compliance.
- Managing and resolving data queries and discrepancies.
- Communicating effectively with investigators, study team members, and internal stakeholders.
- Preparing and presenting monitoring visit reports.
- Ensuring timely reporting of adverse events and safety information.
- Maintaining all study-related documentation and files according to GCP standards.
- Contributing to the development of study protocols and other essential study documents.
Qualifications:
- Bachelor's degree in Life Sciences, Nursing, Pharmacy, or a related field.
- Minimum of 3 years of experience as a Clinical Research Associate (CRA).
- In-depth knowledge of ICH-GCP guidelines and regulatory requirements.
- Experience in oncology clinical trials is a significant advantage.
- Excellent monitoring and data verification skills.
- Strong organizational and time management abilities.
- Proficiency in clinical trial management systems (CTMS) and electronic data capture (EDC) systems.
- Ability to work independently and as part of a remote team.
- Valid UK driving license and willingness to travel extensively.
Remote Clinical Data Manager - Oncology Trials
Posted 3 days ago
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As a remote team member, you will collaborate closely with clinical research associates (CRAs), biostatisticians, and study physicians in a virtual setting. Excellent communication and organizational skills are crucial for effective remote teamwork. You will be proficient in clinical data management software and possess a strong understanding of clinical trial processes. The ideal candidate will have a keen eye for detail, a systematic approach to data handling, and a commitment to upholding the highest standards of data accuracy and regulatory compliance. Experience in oncology trials is highly desirable.
Key Responsibilities:
- Oversee the end-to-end clinical data management process for oncology studies.
- Design, build, and validate clinical databases (e.g., EDC systems) in accordance with study protocols and standards.
- Develop data management plans (DMPs) and data review guidelines.
- Execute data validation checks, identify data discrepancies, and generate/resolve data queries.
- Perform SAE reconciliation and ensure timely reporting of serious adverse events.
- Collaborate with clinical operations and medical teams to ensure data accuracy and completeness.
- Manage database lock processes and ensure data integrity for statistical analysis.
- Contribute to the development and maintenance of data management SOPs.
- Ensure compliance with ICH-GCP guidelines and other relevant regulatory requirements.
- Train and mentor junior data management staff as needed.
Qualifications:
- Bachelor's degree in Life Sciences, Health Information Management, or a related field.
- Minimum of 5 years of experience as a Clinical Data Manager in pharmaceutical or CRO settings.
- Extensive experience with Electronic Data Capture (EDC) systems (e.g., Medidata Rave, Oracle Clinical).
- Strong understanding of CDISC standards (SDTM, ADaM) is essential.
- Experience managing oncology clinical trials is highly preferred.
- Proficiency in data analysis and reporting tools.
- Excellent understanding of ICH-GCP and other relevant regulatory guidelines.
- Exceptional attention to detail and organizational skills.
- Strong written and verbal communication skills for effective remote collaboration.
- Ability to work independently and manage multiple priorities in a remote setting.
This fully remote role, supporting our client's extensive research activities originating from their UK operations, particularly concerning studies linked to Newcastle upon Tyne, Tyne and Wear, UK , offers a competitive compensation package and the opportunity to make a significant impact in oncology clinical research.