46 Participant Role jobs in the United Kingdom

UAT Test Analyst - £300pd (Outside IR35) - ASAP Start - Hybrid (3 days pw central London)

A contract Test Analyst is needed to join an established entertainment client and work on their Service Now offering.

You will be joining an existing team, organising/coordinating UAT and organising test scripts.

The role will be hybrid requiring 3 days PW in their office in central London. Due to this being an immediate need, the interview stage will just be one round meeting with the Test Manager and Program Director.

Please upload your CV if this is of interest and we can run through the requirement in fuller detail.

UAT Test Analyst - £300pd (Outside IR35) - ASAP Start - Hybrid (3 days pw central London)

A contract Test Analyst is needed to join an established entertainment client and work on their Service Now offering.

You will be joining an existing team, organising/coordinating UAT and organising test scripts.

The role will be hybrid requiring 3 days PW in their office in central London. Due to this being an immediate need, the interview stage will just be one round meeting with the Test Manager and Program Director.

Please upload your CV if this is of interest and we can run through the requirement in fuller detail.

Who are we?

Clerkenwell Health is an innovative and leading Research Organisation specialising in the delivery of scientifically grounded clinical trials through our collaborative Contract Research Organisation, extensive Site Network, and pioneering Therapy Development Programme. We focus on supporting mental health and central nervous system (CNS) research, with a particular emphasis on psychedelic drug development.

The Role

We are seeking a skilled and motivated Clinical Pharmacist to join our research delivery team. You’ll play a key role in supporting the safe and effective management of Investigational Medicinal Products (IMPs) across early and late-phase clinical trials, contributing to ground-breaking research in mental health.

This position offers an exciting opportunity to work at the forefront of CNS and psychedelic clinical research, within a highly collaborative and mission-driven environment. You will be central to the delivery of clinical trials, ensuring compliance with Good Clinical Practice (GCP), Good Manufacturing Practice (GMP), and Home Office regulations.

What will the role entail?

• Lead and support the full IMP management cycle: procurement, receipt, storage, dispensing, final checking, accountability, quarantine, disposal, and returns.
• Support feasibility assessments, trial start-up, amendment reviews, and site readiness for new and ongoing studies.
• Ensure compliance with GCP, GMP, GDP, and ICH-GCP, and maintain accurate, inspection-ready documentation.
• Collaborate closely with Principal Investigators, research teams, and external sponsors to ensure timely and high-quality trial delivery.
• Act as a pharmacy representative in Sponsor and regulatory meetings including SIVs, IMs, and audits.
• Support training and supervision of junior staff, and deliver clinical trial training across teams.
• Contribute to internal audits, quality assurance, and continuous improvement of pharmacy and research operations.
• Support Home Office controlled drug compliance and contribute to audit preparation and reporting.

What will you need?

• GPhC registered pharmacist.
• MPharm degree (or equivalent).
• Research experience is desirable, but not essential.
• Strong interpersonal, documentation, and organisational skills.

The process?

An initial screening call with the recruiter followed by a two-stage process with the team via Teams.

Is this the role for you?

At Clerkenwell Health, our core values are Compassion , Collaboration , Innovation , and Integrity . If you're passionate about improving mental health outcomes through research and ready to lead pharmacy excellence in clinical trials - we’d love to hear from you.

Job purpose

At Blue Earth Diagnostics , which is part of the Bracco Group, our mission is to transform the clinical management of patients with cancer by developing innovative molecular imaging technologies. Our team is made up of industry leaders in the field of radiopharmaceutical development and commercialization. Blue Earth Diagnostics is a dynamic and growing company with an approved product already on the market in the USA and in Europe, and a development pipeline of diagnostic radiopharmaceuticals.

The Clinical Trial Administrator (CTA) is responsible for supporting the Clinical Trial Manager (CTM) and wider Clinical Operations team for their assigned projects. This position is fundamental to the efficient execution of trials and supports overall compliance with Good Clinical Practice (GCP) and company Standard Operating Procedures (SOP’s).

Main Responsibilities, Activities, Duties and Tasks

• Set-up, prepare, handle, distribute, file and archive all essential and supportive clinical study documentation within the TMF (Trial Master File; paper or electronic), and be the point of contact for all queries on the assigned TMF(s).
• Responsible for periodic reviews of the study files for completeness.
• Support the assigned studies by maintaining adequate tracking of study specific documentation including but not limited to BED specific study timelines, Protocols, Investigators Brochures, Trial Master File Configuration Manuals, Combined Project and Sponsor Oversight plans, Informed Consent/Assent Documents.
• Support the assigned studies by maintaining adequate tracking of study statuses including but not limited to site set-up and participant recruitment.
• Assist the CTM in preparation for any internal audits or inspections and responding to any findings.
• Assist the Clinical Operations Team with creating purchase order numbers & general set-up and tracking of study contracts & budgets within BED financial software (Accenture SAP).
• Support the Clinical Operations Team with setting up face-to-face meetings, video conferences (VCs), Teleconferences (TCs) or other meeting formats, take minutes for Internal Project Team meetings and any other meetings as required.
• Perform other Trial, Project or Department related duties, as assigned. Other duties as determined by business needs.

Education

Bachelor’s degree or equivalent in life science or allied health fields such as nursing, pharmacy or health science, or long-standing experience in a similar role.

Professional Experience, Knowledge & Technical Skills

• Industry or clinical trial setting as a trial/study coordinator
• In depth knowledge of Clinical Trial conduct and eTMF setup and management
• Knowledge of current ICH/GCP guidelines
• Proven skills in minute taking
• Excellent organisational skills
• Ability to effectively prioritise workload
• Previous experience working in a matrix organisation
• Demonstrates collaboration skills and flexibility
• Ability to work under pressure
• Flexibility to work in a rapidly growing/changing organisation
• Familiarity with Accenture SAP (preferable)

Soft Skills – Company Values & Behaviours

• Excellent oral & written communication skills.
• Ability to influence and build relationships/earn credibility quickly across broad global constituencies with competing priorities.
• Strong coaching, facilitation, and organizational skills.
• Team player.

Global Study Manager

Duration - 12 months (interim)

Location - Remote

Inside IR35

The Global Study Manager is responsible for supporting the delivery of clinical studies ensuring quality and compliance. The exact accountabilities will differ depending on the exact nature of the clinical program, so a high degree of flexibility is required.

Responsibilities:

• Contribute to the development of study documents as appropriate as well as any updates/amendments, ensuring template and version compliance.

• Lead the preparation of country specific agreements, confidentiality agreements, clinical trial applications and other applicable country documents.

• Manage the set-up of third-party vendors assessing initial statement of work and budget, as well as the change order process.

• Provide input to data management documents (e.g. Case Report Form, Data Validation Specifications), and interface with data management representatives and sites to facilitate the delivery of study data.

• Initiate contract/budget requests and track ongoing status; facilitate generation of purchase orders, review vendor invoices and assist in tracking spend against approved budget.

• Ensure the supply of Investigational product and study materials by liaising with Drug Supply or external service providers as appropriate.

• Oversight of third party vendors, global / local internal staff and investigator sites to support effective delivery of a study and its regulatory documents from development of the protocol through to the Clinical Study Report.

• Provide oversight of and support recruitment and data delivery as well as risk mitigation strategies.

• Assist in the clinical trial insurance process; track approvals, revisions and renewals of certificates.

• Monitor study conduct and progress, proactively identifying and resolving issues which may impact delivery of the study to the necessary quality, timelines or budget.

• Support risk management and quality efforts to ensure study compliance.

• Support set-up, maintenance, closeout and archiving of the Trial Master File (TMF), ensuring continual inspection readiness.

• Prepare presentation material for meetings, newsletters and websites.

• Support the study team in the implementation of audits and regulatory inspections.

• Contribute to review of new/amended/unique SOPs and guidance documents.

Essential Skills/Requirements:

University degree / Bachelor’s degree, preferably in medical or biological science, or discipline associated with Clinical Research, or equivalent experience

• Minimum of 3-4 years of progressive clinical trial experience

• Experience of working with and delivering through strategic partners and 3rd party vendors

• Excellent knowledge of ICH-GCP principles

• Demonstrated verbal and written communication skills

• Early Phase experience (phase I and IIa)

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, colour, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements

About Summit:

Ivonescimab, known as SMT112, is a novel, potential first-in-class investigational bispecific antibody combining the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects associated with blocking VEGF into a single molecule. Ivonescimab displays unique cooperative binding to each of its intended targets with multifold higher affinity when in the presence of both PD-1 and VEGF.

Summit has begun its clinical development of ivonescimab in non-small cell lung cancer (NSCLC), with three active Phase III trials:

• HARMONi is a Phase III clinical trial which intends to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who have progressed after treatment with a 3rd generation EGFR TKI (e.g., osimertinib).
• HARMONi-3 is a Phase III clinical trial which is designed to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.
• HARMONi-7 is a Phase III clinical trial which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC whose tumors have high PD-L1 expression.

Ivonescimab is an investigational therapy that is not approved by any regulatory authority in Summit’s license territories, including the United States and Europe. Ivonescimab was approved for marketing authorization in China in May 2024. Ivonescimab was granted Fast Track designation by the US Food & Drug Administration (FDA) for the HARMONi clinical trial setting .

Overview of Role:

The Clinical Trial Manager is a highly autonomous and experienced clinical operations professional responsible for all aspects of Clinical Trial Management for global studies. Responsible for study start up and maintenance through study close out. Coordinates, leads and drives leads Summit cross functional team members, CROs and vendors to successfully deliver clinical studies. Responsible for all performance metrics and quality of deliverables in the clinical trial.

Role and Responsibilities:

• Oversees study scope, quality, timelines, and budget with the internal Summit functional leads, CRO and vendors to ensure that overall project objectives are met
• Initiates and builds solid professional relationships with key opinion leaders and clinical site staff
• Partners with the CRO to ensure robust patient enrollment strategies are developed and carried out effectively to ensure patient enrollment is completed on time
• Partners with the CRO to ensure robust ongoing data monitoring strategies are developed and carried out effectively to ensure delivery of high-quality data
• Proactive identification and management of study related risks
• Responsible for the development and management of clinical trial documents including (but not limited to) protocols, Case Report Forms (CRFs), consent documents, confidentiality agreements
• Responsible for reviewing and managing study related plans, processes including
• Investigator agreements (CTA), CRFs, CRF guidelines, statistical / pharmacokinetic analysis plans, monitoring plan, data management, safety monitoring
• Responsible for reviewing CRO and vendor contracts/work orders and specifications to enable study objectives to be met
• Reviews and approves essential document packages to enable timely site activations
• Reviews pre-study, study initiation, interim monitoring visit and at study closeout visit report
• Provides close oversight on the findings on the monitoring reports and loops back with broader team to provide updates
• Directs investigator performance and adherence to protocol, and proactively addresses conduct issues and enrollment problems, as necessary
• Responsible for oversight on the maintenance of the TMF and completeness at the end of the study
• Perform periodic QC of the TMF
• Oversee the creation and execution of clinical trial activities in accordance with Good Clinical Practices. Ensure compliance of clinical trials with national and international regulatory requirements and co-monitoring the assigned clinical trial following company SOPs
• Ensures the study is “inspection ready” always
• Responsible for oversight and coaching of the functional activities of Clinical Trial Associates allocated to the project
• All other duties as assigned

Experience, Education and Specialized Knowledge and Skills:

• Bachelor’s degree or equivalent in life science, nursing, pharmacy, medical laboratory technology, or other health/medical related area preferred
• 5+ years of clinical project management experience in conducting international clinical trials in sponsor Pharma/Biotech organization
• Prior phase II and III experience required
• A solid understanding of the drug development process, ICH guidelines/GCP and specifically, each step within the clinical trial process
• Experience with budget forecasting and management
• Experience with clinical studies in oncology
• Ability to travel internationally to visit clinical sites and for study meetings. Amount will vary upon project needs (up to 20%)
• Proven proficiency in overseeing large complex studies being managed in house and by a CRO
• Demonstrated ability to lead teams and work in a fast-paced team environment
• Experienced and enjoys building relationships with KOLs and site personnel
• Ability to successfully engage and work collaboratively with overseas clinical operations team members/colleagues
• Demonstrated ability to build and deliver on patient enrollment strategies
• Excellent interpersonal and decision-making skills. Demonstrates innovation, possesses drive, energy, and enthusiasm to deliver the program objectives
• Demonstrated ability to comprehend complex scientific concepts and data
• Proficient in reviewing and assessing clinical data
• Possesses excellent planning, time management & coordination skills
• Demonstrated ability to problem solve and use clear judgment in relation to regulatory requirements, interactions with external parties, timelines, and complex clinical programs
• Experience in working in a small organization
• Excellent written and oral communication skills

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at to obtain prior written authorization before referring any candidates to Summit.

We are seeking an experienced Clinical Trial Manager to join a London-based biotech and lead the planning, execution, and delivery of clinical trials. The successful candidate will excel in fast-paced, dynamic biotech settings and be committed to driving trials that meet the highest standards of quality, compliance, and operational excellence.

Responsibilities:

• Lead the design, start-up, and execution of clinical trials, ensuring projects are completed on schedule, within scope, and aligned with budgetary expectations.
• Serve as the primary sponsor contact for CROs, investigators, and providers.
• Oversee CRO performance, including reviewing monitoring outputs and KPIs.
• Work closely with Regulatory Affairs on ethics/regulatory submissions, ensuring alignment with ICH-GCP guidelines and current UK/EU regulations.
• Maintain trial inspection readiness, overseeing safety reporting, audit response, and vendor governance.
• Develop and review protocols, informed consent forms, and study reports.
• Drive risk management, issue resolution, and collaboration across cross-functional teams.
• Play an active role in refining operational processes and SOPs within the Clinical Operations function.

Requirements:

• Bachelor’s degree (or equivalent) in a life science or health-related discipline.
• Minimum of 8 years in clinical trial management across pharma, biotech, or CROs.
• Site monitoring experience or proven ability to critically evaluate CRO monitoring performance.
• In-depth understanding of ICH-GCP and global regulatory requirements, with strong understanding of upcoming UK/EU regulatory changes (e.g., UK CTR 2026).
• Demonstrated success in managing CROs and vendors, including financial oversight.
• Skilled at balancing multiple priorities and tight timelines.
• Proficient in navigating lean, fast-paced environments; direct experience in biotech settings is valued.
• Strong interpersonal and communication skills, with proven ability to manage internal stakeholders with accountability and transparency.
• Able to work on-site in central London in a hybrid capacity.

We are seeking an experienced Clinical Trial Manager to join a London-based biotech and lead the planning, execution, and delivery of clinical trials. The successful candidate will excel in fast-paced, dynamic biotech settings and be committed to driving trials that meet the highest standards of quality, compliance, and operational excellence.

Responsibilities:

• Lead the design, start-up, and execution of clinical trials, ensuring projects are completed on schedule, within scope, and aligned with budgetary expectations.
• Serve as the primary sponsor contact for CROs, investigators, and providers.
• Oversee CRO performance, including reviewing monitoring outputs and KPIs.
• Work closely with Regulatory Affairs on ethics/regulatory submissions, ensuring alignment with ICH-GCP guidelines and current UK/EU regulations.
• Maintain trial inspection readiness, overseeing safety reporting, audit response, and vendor governance.
• Develop and review protocols, informed consent forms, and study reports.
• Drive risk management, issue resolution, and collaboration across cross-functional teams.
• Play an active role in refining operational processes and SOPs within the Clinical Operations function.

Requirements:

• Bachelor’s degree (or equivalent) in a life science or health-related discipline.
• Minimum of 8 years in clinical trial management across pharma, biotech, or CROs.
• Site monitoring experience or proven ability to critically evaluate CRO monitoring performance.
• In-depth understanding of ICH-GCP and global regulatory requirements, with strong understanding of upcoming UK/EU regulatory changes (e.g., UK CTR 2026).
• Demonstrated success in managing CROs and vendors, including financial oversight.
• Skilled at balancing multiple priorities and tight timelines.
• Proficient in navigating lean, fast-paced environments; direct experience in biotech settings is valued.
• Strong interpersonal and communication skills, with proven ability to manage internal stakeholders with accountability and transparency.
• Able to work on-site in central London in a hybrid capacity.

About Summit:

Ivonescimab, known as SMT112, is a novel, potential first-in-class investigational bispecific antibody combining the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects associated with blocking VEGF into a single molecule. Ivonescimab displays unique cooperative binding to each of its intended targets with multifold higher affinity when in the presence of both PD-1 and VEGF.

Summit has begun its clinical development of ivonescimab in non-small cell lung cancer (NSCLC), with three active Phase III trials:

• HARMONi is a Phase III clinical trial which intends to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who have progressed after treatment with a 3rd generation EGFR TKI (e.g., osimertinib).
• HARMONi-3 is a Phase III clinical trial which is designed to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.
• HARMONi-7 is a Phase III clinical trial which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC whose tumors have high PD-L1 expression.

Ivonescimab is an investigational therapy that is not approved by any regulatory authority in Summit’s license territories, including the United States and Europe. Ivonescimab was approved for marketing authorization in China in May 2024. Ivonescimab was granted Fast Track designation by the US Food & Drug Administration (FDA) for the HARMONi clinical trial setting .

Overview of Role:

The Clinical Trial Manager is a highly autonomous and experienced clinical operations professional responsible for all aspects of Clinical Trial Management for global studies. Responsible for study start up and maintenance through study close out. Coordinates, leads and drives leads Summit cross functional team members, CROs and vendors to successfully deliver clinical studies. Responsible for all performance metrics and quality of deliverables in the clinical trial.

Role and Responsibilities:

• Oversees study scope, quality, timelines, and budget with the internal Summit functional leads, CRO and vendors to ensure that overall project objectives are met
• Initiates and builds solid professional relationships with key opinion leaders and clinical site staff
• Partners with the CRO to ensure robust patient enrollment strategies are developed and carried out effectively to ensure patient enrollment is completed on time
• Partners with the CRO to ensure robust ongoing data monitoring strategies are developed and carried out effectively to ensure delivery of high-quality data
• Proactive identification and management of study related risks
• Responsible for the development and management of clinical trial documents including (but not limited to) protocols, Case Report Forms (CRFs), consent documents, confidentiality agreements
• Responsible for reviewing and managing study related plans, processes including
• Investigator agreements (CTA), CRFs, CRF guidelines, statistical / pharmacokinetic analysis plans, monitoring plan, data management, safety monitoring
• Responsible for reviewing CRO and vendor contracts/work orders and specifications to enable study objectives to be met
• Reviews and approves essential document packages to enable timely site activations
• Reviews pre-study, study initiation, interim monitoring visit and at study closeout visit report
• Provides close oversight on the findings on the monitoring reports and loops back with broader team to provide updates
• Directs investigator performance and adherence to protocol, and proactively addresses conduct issues and enrollment problems, as necessary
• Responsible for oversight on the maintenance of the TMF and completeness at the end of the study
• Perform periodic QC of the TMF
• Oversee the creation and execution of clinical trial activities in accordance with Good Clinical Practices. Ensure compliance of clinical trials with national and international regulatory requirements and co-monitoring the assigned clinical trial following company SOPs
• Ensures the study is “inspection ready” always
• Responsible for oversight and coaching of the functional activities of Clinical Trial Associates allocated to the project
• All other duties as assigned

Experience, Education and Specialized Knowledge and Skills:

• Bachelor’s degree or equivalent in life science, nursing, pharmacy, medical laboratory technology, or other health/medical related area preferred
• 5+ years of clinical project management experience in conducting international clinical trials in sponsor Pharma/Biotech organization
• Prior phase II and III experience required
• A solid understanding of the drug development process, ICH guidelines/GCP and specifically, each step within the clinical trial process
• Experience with budget forecasting and management
• Experience with clinical studies in oncology
• Ability to travel internationally to visit clinical sites and for study meetings. Amount will vary upon project needs (up to 20%)
• Proven proficiency in overseeing large complex studies being managed in house and by a CRO
• Demonstrated ability to lead teams and work in a fast-paced team environment
• Experienced and enjoys building relationships with KOLs and site personnel
• Ability to successfully engage and work collaboratively with overseas clinical operations team members/colleagues
• Demonstrated ability to build and deliver on patient enrollment strategies
• Excellent interpersonal and decision-making skills. Demonstrates innovation, possesses drive, energy, and enthusiasm to deliver the program objectives
• Demonstrated ability to comprehend complex scientific concepts and data
• Proficient in reviewing and assessing clinical data
• Possesses excellent planning, time management & coordination skills
• Demonstrated ability to problem solve and use clear judgment in relation to regulatory requirements, interactions with external parties, timelines, and complex clinical programs
• Experience in working in a small organization
• Excellent written and oral communication skills

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at to obtain prior written authorization before referring any candidates to Summit.