507 Pharmaceutical Development jobs in the United Kingdom
Principal Formulation Scientist - Pharmaceutical Development
NR3 1DE Norwich, Eastern
£70000 Annually
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Posted 5 days ago
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Our client, a leading pharmaceutical company, is seeking an experienced Principal Formulation Scientist to lead innovative drug development projects. This role is based in **Norwich, Norfolk, UK**. You will be responsible for designing, developing, and optimizing novel drug delivery systems and formulations across various therapeutic areas. Key responsibilities include planning and executing pre-formulation studies, developing solid dosage forms, parenteral products, or topical formulations, and conducting stability studies to ensure product quality and efficacy. You will work collaboratively with analytical development, process development, and regulatory affairs teams to advance candidates from early-stage development through to clinical trials and commercialization. The ideal candidate will have a PhD or Master's degree in Pharmaceutics, Chemistry, Chemical Engineering, or a related discipline, with a minimum of 7 years of experience in pharmaceutical formulation development. Proven expertise in various dosage forms, particularly oral solids and/or injectables, is required. Strong knowledge of excipient science, drug degradation pathways, and manufacturing processes is essential. Experience with analytical techniques used for formulation characterization (e.g., HPLC, DSC, XRD) and a solid understanding of GMP guidelines and regulatory requirements are crucial. Excellent leadership, problem-solving, and communication skills are necessary to mentor junior scientists and effectively present data and project updates to cross-functional teams and management. This is an exciting opportunity to contribute to the development of life-changing medicines within a dynamic research environment.
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0
Senior Formulation Scientist - Pharmaceutical Development
SR2 0SW Sunderland, North East
£55000 Annually
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Posted 17 days ago
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A leading pharmaceutical research and development company based in **Sunderland** is looking for a highly experienced Senior Formulation Scientist to join their innovative drug development team. This full-time role is critical in designing, developing, and optimizing novel drug formulations to enhance therapeutic efficacy and patient compliance. The ideal candidate will have a strong background in pharmaceutical sciences, a proven track record in formulation development, and a passion for bringing new medicines to patients.
Responsibilities:
Responsibilities:
- Lead the formulation development of new drug candidates, from pre-clinical through to clinical phases.
- Design and execute experimental studies to develop various dosage forms, including oral solid dosage forms, injectables, and topical preparations.
- Investigate and select appropriate excipients and formulation technologies to achieve desired drug product performance.
- Conduct pre-formulation studies, including solubility, stability, and compatibility assessments.
- Develop and validate analytical methods for characterizing formulations and drug products.
- Optimize formulations to ensure stability, bioavailability, and manufacturability.
- Prepare detailed study protocols, reports, and regulatory submission documents (e.g., CMC sections).
- Collaborate with analytical development, process development, and quality assurance teams.
- Stay abreast of regulatory guidelines (e.g., FDA, EMA) and industry best practices in formulation science.
- Mentor and guide junior scientists and technicians within the formulation team.
- Troubleshoot formulation and manufacturing issues, providing effective solutions.
- Contribute to the strategic direction of the formulation development pipeline.
- Ph.D. or Master's degree in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related discipline.
- Minimum of 5-7 years of hands-on experience in pharmaceutical formulation development.
- Proven expertise in developing various dosage forms, with a strong understanding of associated technologies and equipment.
- Proficiency in pre-formulation techniques, solid-state characterization, and drug delivery systems.
- Experience with analytical techniques commonly used in pharmaceutical development (e.g., HPLC, dissolution testing, particle size analysis).
- Familiarity with Good Manufacturing Practices (GMP) and regulatory requirements for drug development.
- Excellent scientific judgment, problem-solving, and critical thinking skills.
- Strong project management abilities and experience working in a team-oriented environment.
- Excellent written and verbal communication skills, with the ability to present complex scientific data clearly.
- Experience with controlled-release technologies or novel drug delivery systems is a significant advantage.
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1
Lead Pharmaceutical Development Scientist
NG1 1AA Nottingham, East Midlands
£70000 Annually
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We are looking for an accomplished Lead Pharmaceutical Development Scientist to join our client's innovative research and development team. This critical, non-remote role is based in the heart of **Nottingham, Nottinghamshire, UK**, and requires a hands-on approach to pioneering new drug formulations and manufacturing processes. You will lead a team of scientists and technicians, driving projects from early-stage concept development through to clinical trial material manufacturing and process validation.
As the Lead Pharmaceutical Development Scientist, you will be responsible for designing and executing experimental strategies, interpreting complex data, and troubleshooting development challenges. You will play a key role in ensuring that new pharmaceutical products meet stringent quality, efficacy, and safety standards. Collaboration with internal departments such as analytical development, regulatory affairs, and quality assurance will be vital to the success of your projects. Your leadership will be crucial in mentoring junior scientists, fostering a culture of scientific excellence, and ensuring the efficient and timely progression of development pipelines.
Key Responsibilities:
Qualifications:
This is a premier opportunity for a seasoned Pharmaceutical Development Scientist to lead critical R&D initiatives within a leading drug development organization. We are looking for individuals passionate about innovation and committed to making a difference in patient care.
As the Lead Pharmaceutical Development Scientist, you will be responsible for designing and executing experimental strategies, interpreting complex data, and troubleshooting development challenges. You will play a key role in ensuring that new pharmaceutical products meet stringent quality, efficacy, and safety standards. Collaboration with internal departments such as analytical development, regulatory affairs, and quality assurance will be vital to the success of your projects. Your leadership will be crucial in mentoring junior scientists, fostering a culture of scientific excellence, and ensuring the efficient and timely progression of development pipelines.
Key Responsibilities:
- Lead the formulation development of novel drug products, including solid dosage forms, injectables, and other relevant delivery systems.
- Design and execute pre-formulation studies, stability testing, and compatibility studies.
- Develop and optimize manufacturing processes for clinical trial materials and commercial production, ensuring scalability and robustness.
- Conduct comprehensive data analysis and interpretation to guide formulation and process decisions.
- Troubleshoot formulation and process-related issues encountered during development.
- Prepare technical documentation, including development reports, validation protocols, and regulatory submission documents (e.g., IND, NDA sections).
- Mentor and guide a team of pharmaceutical scientists and technicians, fostering their professional growth and technical expertise.
- Collaborate effectively with analytical development, quality control, quality assurance, and regulatory affairs teams.
- Stay abreast of the latest advancements in pharmaceutical sciences, drug delivery technologies, and manufacturing techniques.
- Ensure all activities are conducted in compliance with cGMP guidelines and relevant regulatory requirements.
Qualifications:
- A Master's or PhD in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related discipline.
- A minimum of 7 years of progressive experience in pharmaceutical formulation and process development, with at least 3 years in a leadership or supervisory role.
- Proven track record of successfully developing and scaling up pharmaceutical products.
- In-depth knowledge of drug product formulation, excipient selection, and drug delivery systems.
- Hands-on experience with various pharmaceutical manufacturing equipment and processes.
- Strong understanding of analytical techniques relevant to pharmaceutical characterization and quality control.
- Excellent problem-solving, critical thinking, and data interpretation skills.
- Strong leadership, team management, and communication abilities.
- Familiarity with cGMP regulations and regulatory submission requirements.
This is a premier opportunity for a seasoned Pharmaceutical Development Scientist to lead critical R&D initiatives within a leading drug development organization. We are looking for individuals passionate about innovation and committed to making a difference in patient care.
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2
Lead Pharmaceutical Development Scientist
AB10 1AA Aberdeen, Scotland
£70000 Annually
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Posted today
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Our client, a pioneering pharmaceutical company, is seeking an accomplished Lead Pharmaceutical Development Scientist to join their innovative R&D team. This hybrid role is instrumental in driving the development of novel drug formulations from early-stage research through to clinical trial readiness. You will lead a team of scientists and researchers, oversee critical laboratory work, and contribute significantly to the strategic direction of drug development projects. The ideal candidate will possess extensive expertise in pharmaceutical sciences, formulation development, and a strong understanding of regulatory requirements.
Key Responsibilities:
Qualifications:
Key Responsibilities:
- Lead and mentor a team of pharmaceutical scientists and technicians in formulation development activities.
- Design and execute experimental plans for the development of solid dosage forms, sterile products, or other relevant drug delivery systems.
- Conduct pre-formulation studies, including characterisation of active pharmaceutical ingredients (APIs) and excipients.
- Optimise formulations to achieve desired pharmacokinetic profiles, stability, and manufacturability.
- Oversee the scale-up of laboratory processes to pilot and manufacturing scales.
- Collaborate closely with analytical development, CMC, and regulatory affairs teams.
- Prepare and review technical reports, study protocols, and regulatory submission documents.
- Stay abreast of scientific advancements, new technologies, and regulatory guidelines in pharmaceutical development.
- Troubleshoot formulation and process-related issues.
- Contribute to the strategic planning and pipeline progression of drug development projects.
Qualifications:
- PhD or Master's degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related discipline.
- Minimum of 7 years of experience in pharmaceutical formulation development and drug product design.
- Proven experience in leading scientific projects and teams.
- In-depth knowledge of drug delivery systems, physical pharmaceutics, and process development.
- Familiarity with GMP guidelines and regulatory submission requirements (e.g., FDA, EMA).
- Excellent analytical, problem-solving, and critical thinking skills.
- Strong written and verbal communication skills.
- Ability to manage multiple projects and priorities effectively.
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3
Research Scientist - Pharmaceutical Development
OX1 3PT Oxford, South East
£45000 Annually
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Posted 2 days ago
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Our client, a world-renowned pharmaceutical research organisation, is seeking a talented Research Scientist to join their drug discovery and development team in Oxford, Oxfordshire, UK . This is a hands-on laboratory-based role focused on advancing innovative therapeutic candidates through the early stages of development. You will be responsible for designing and executing experiments, analysing complex data, and contributing to the scientific strategy for key projects.
Key Responsibilities:
Qualifications:
This role is based on-site and offers an exceptional opportunity to contribute to cutting-edge pharmaceutical research in the vibrant scientific hub of Oxford, Oxfordshire, UK .
Key Responsibilities:
- Design, optimise, and perform in vitro and ex vivo experiments to evaluate drug efficacy and mechanism of action.
- Develop and validate new assays for drug screening and characterisation.
- Conduct thorough data analysis, interpretation, and reporting of experimental results.
- Collaborate with cross-functional teams, including medicinal chemists, biologists, and pharmacologists.
- Contribute to the scientific literature through publications and presentations.
- Maintain accurate and detailed laboratory notebooks and project documentation.
- Ensure compliance with laboratory safety regulations and company policies.
- Troubleshoot experimental procedures and equipment.
- Stay updated with the latest scientific advancements in the relevant therapeutic areas.
- Present findings at internal project meetings and scientific conferences.
Qualifications:
- PhD or MSc in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline.
- Demonstrated experience in pharmaceutical research, with a focus on drug discovery or development.
- Hands-on experience with a variety of laboratory techniques relevant to the field (e.g., cell culture, ELISA, Western blotting, flow cytometry).
- Proficiency in data analysis software (e.g., GraphPad Prism, R).
- Strong understanding of biological pathways and disease mechanisms.
- Excellent written and verbal communication skills.
- Ability to work independently and as part of a collaborative research team.
- Problem-solving skills and a meticulous approach to experimental work.
- Experience in a specific therapeutic area (e.g., oncology, immunology) is a plus.
This role is based on-site and offers an exceptional opportunity to contribute to cutting-edge pharmaceutical research in the vibrant scientific hub of Oxford, Oxfordshire, UK .
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4
Lead Pharmaceutical Development Scientist
RG1 1NN Reading, South East
£75000 Annually
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Posted 5 days ago
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Our client, a pioneering pharmaceutical company, is actively searching for a highly accomplished Lead Pharmaceutical Development Scientist to join our innovative team. This is a fully remote position, offering the chance to contribute to critical drug development processes from anywhere in the world. You will be instrumental in driving the formulation and development of new drug products, from early-stage research through to pre-clinical and clinical stages. Your responsibilities will encompass leading the design, execution, and interpretation of experiments related to drug formulation, process development, and analytical method development. You will manage a portfolio of projects, ensuring timely delivery and adherence to stringent regulatory guidelines (e.g., GMP, ICH). This role requires a deep understanding of pharmaceutics, drug delivery systems, and relevant analytical techniques. You will also be responsible for mentoring junior scientists, fostering a collaborative and innovative research environment. Strong project management skills, excellent problem-solving capabilities, and a proven ability to communicate complex scientific information effectively to cross-functional teams and stakeholders are essential. The ideal candidate will possess a PhD or Master's degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related discipline, with a minimum of 8 years of experience in pharmaceutical R&D. Experience with various dosage forms (e.g., oral solids, injectables, topical formulations) and regulatory submissions is highly desirable. This is a remote-first opportunity, requiring exceptional self-discipline, communication, and collaboration skills to work effectively within a global, distributed team. You will leverage cutting-edge digital tools to collaborate, manage projects, and contribute to the advancement of life-saving medicines. The role is anchored conceptually to our client's operations in **Reading, Berkshire, UK**, but executed entirely remotely.
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5
Senior Pharmaceutical Development Scientist
BN1 1AA East Sussex, South East
£60000 Annually
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Posted 5 days ago
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Job Description
Our client is seeking an accomplished Senior Pharmaceutical Development Scientist to join their innovative R&D department in Brighton, East Sussex, UK . This role offers a unique opportunity to contribute to the development of novel pharmaceutical products from discovery through to clinical trials.
The Senior Pharmaceutical Development Scientist will be responsible for designing, executing, and optimizing formulation development studies for various dosage forms, including oral solids, injectables, and topical preparations. You will play a key role in characterizing drug substances and excipients, developing robust formulations, and conducting stability studies. The ideal candidate will possess a deep understanding of pharmaceutical sciences, regulatory requirements, and GMP principles.
Key Responsibilities:
Qualifications:
The Senior Pharmaceutical Development Scientist will be responsible for designing, executing, and optimizing formulation development studies for various dosage forms, including oral solids, injectables, and topical preparations. You will play a key role in characterizing drug substances and excipients, developing robust formulations, and conducting stability studies. The ideal candidate will possess a deep understanding of pharmaceutical sciences, regulatory requirements, and GMP principles.
Key Responsibilities:
- Lead the formulation development of new drug candidates, from pre-clinical through to clinical phases.
- Design and conduct experiments to characterize drug substances, excipients, and finished drug products.
- Develop and optimize robust manufacturing processes for various dosage forms.
- Perform stability studies according to ICH guidelines and analyze results.
- Prepare documentation for regulatory submissions (e.g., IND, NDA).
- Collaborate with analytical development, process chemistry, and manufacturing teams.
- Troubleshoot formulation and process-related issues.
- Stay current with advancements in pharmaceutical technology and regulatory landscape.
- Mentor junior scientists and contribute to a culture of scientific excellence.
- Ensure all activities are conducted in compliance with GMP and other relevant regulations.
Qualifications:
- Ph.D. or Master's degree in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related field.
- Minimum of 5 years of experience in pharmaceutical formulation development.
- Strong knowledge of formulation science, drug delivery systems, and dosage form design.
- Experience with GMP environments and regulatory guidelines (FDA, EMA).
- Proficiency in analytical techniques relevant to pharmaceutical development (e.g., HPLC, dissolution testing, particle size analysis).
- Excellent problem-solving, critical thinking, and data interpretation skills.
- Strong written and verbal communication abilities.
- Proven ability to manage projects and work effectively in a multidisciplinary team.
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6
Research Scientist (Pharmaceutical Development)
SR1 2AE Sunderland, North East
£50000 Annually
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Posted 5 days ago
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Our client is a pioneering pharmaceutical company at the forefront of drug discovery and development. We are seeking a talented and dedicated Research Scientist to join their innovative R&D team. This is a fully remote position, allowing you to contribute your expertise from any location within the UK. The successful candidate will play a key role in the early-stage development of novel therapeutic agents, contributing to critical research projects that aim to improve patient outcomes. This role offers an exciting opportunity to work with cutting-edge technologies and collaborate with a team of highly skilled scientists. Key responsibilities include:
- Designing and executing experiments to investigate biological pathways and therapeutic targets.
- Analyzing experimental data, interpreting results, and generating comprehensive reports.
- Developing and validating new assays and methodologies.
- Contributing to the planning and execution of research projects, adhering to timelines and objectives.
- Collaborating with internal and external research partners.
- Maintaining detailed laboratory notebooks and documentation in compliance with regulatory standards.
- Staying abreast of the latest scientific literature and advancements in the field.
- Presenting research findings at internal and external scientific meetings.
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7
Research Scientist - Pharmaceutical Development
BN1 2AA East Sussex, South East
£40000 Annually
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Posted 13 days ago
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Job Description
A pioneering pharmaceutical company is seeking a dedicated Research Scientist to join its dynamic drug discovery and development team based in Brighton, East Sussex, UK . This is an outstanding opportunity for a motivated scientist to contribute to the advancement of novel therapeutic agents within a cutting-edge research environment.
The Research Scientist will play a pivotal role in the design, execution, and analysis of experiments aimed at identifying and validating new drug targets and developing innovative pharmaceutical compounds. Responsibilities include conducting complex laboratory procedures, maintaining meticulous experimental records, and interpreting scientific data. The role requires a strong understanding of relevant scientific principles and methodologies, as well as the ability to work independently and as part of a collaborative research team.
Key contributions will involve literature reviews, experimental planning, data analysis using statistical software, and the preparation of reports and presentations for internal and external stakeholders. The scientist will be expected to stay abreast of the latest scientific advancements in their field and contribute to the intellectual property generation of the company. Adherence to stringent laboratory safety protocols and good laboratory practices (GLP) is paramount.
Key Responsibilities:
The Research Scientist will play a pivotal role in the design, execution, and analysis of experiments aimed at identifying and validating new drug targets and developing innovative pharmaceutical compounds. Responsibilities include conducting complex laboratory procedures, maintaining meticulous experimental records, and interpreting scientific data. The role requires a strong understanding of relevant scientific principles and methodologies, as well as the ability to work independently and as part of a collaborative research team.
Key contributions will involve literature reviews, experimental planning, data analysis using statistical software, and the preparation of reports and presentations for internal and external stakeholders. The scientist will be expected to stay abreast of the latest scientific advancements in their field and contribute to the intellectual property generation of the company. Adherence to stringent laboratory safety protocols and good laboratory practices (GLP) is paramount.
Key Responsibilities:
- Design, conduct, and optimize experiments in drug discovery and development.
- Perform complex laboratory techniques and assays relevant to pharmaceutical research.
- Analyze and interpret scientific data, drawing meaningful conclusions.
- Maintain accurate and comprehensive laboratory notebooks and reports.
- Contribute to the development of research strategies and experimental protocols.
- Stay current with scientific literature and emerging trends in the pharmaceutical industry.
- Collaborate effectively with cross-functional teams, including chemists, biologists, and clinicians.
- Prepare and present research findings at scientific meetings and conferences.
- Ensure compliance with all safety regulations and laboratory standards.
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8
Research Scientist - Pharmaceutical Development
G1 1AA Glasgow, Scotland
£45000 Annually
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Posted 13 days ago
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Join a leading pharmaceutical company as a Research Scientist focused on innovative drug development. This challenging role is based at our state-of-the-art research facility in Glasgow, Scotland, UK , requiring your presence on-site to leverage our advanced laboratory equipment and collaborative environment. You will be instrumental in the early-stage research and development of novel therapeutic agents, from target identification and validation through to preclinical studies. Your core responsibilities will include designing and executing complex experiments, analysing biological data, interpreting results, and contributing to the preparation of scientific publications and regulatory documents.
We seek highly motivated individuals with a PhD in Pharmacology, Biochemistry, Molecular Biology, or a closely related life science discipline. Proven experience in drug discovery methodologies, including assay development, in vitro and in vivo pharmacology, is essential. Strong understanding of cellular and molecular mechanisms relevant to disease pathways is required. The ideal candidate will possess excellent laboratory skills, a critical and analytical mind, and the ability to troubleshoot experimental challenges effectively. Familiarity with relevant scientific software and data analysis tools is a must. Excellent written and verbal communication skills are necessary for presenting findings to internal teams and external collaborators.
This is an exceptional opportunity to contribute to cutting-edge pharmaceutical research and make a tangible impact on patient health. You will work alongside a team of dedicated scientists and researchers, fostering a collaborative and intellectually stimulating atmosphere. We offer continuous professional development, access to advanced technologies, and a clear career path for growth within the organisation. Be part of a company that is committed to improving lives through scientific excellence and innovation.
We seek highly motivated individuals with a PhD in Pharmacology, Biochemistry, Molecular Biology, or a closely related life science discipline. Proven experience in drug discovery methodologies, including assay development, in vitro and in vivo pharmacology, is essential. Strong understanding of cellular and molecular mechanisms relevant to disease pathways is required. The ideal candidate will possess excellent laboratory skills, a critical and analytical mind, and the ability to troubleshoot experimental challenges effectively. Familiarity with relevant scientific software and data analysis tools is a must. Excellent written and verbal communication skills are necessary for presenting findings to internal teams and external collaborators.
This is an exceptional opportunity to contribute to cutting-edge pharmaceutical research and make a tangible impact on patient health. You will work alongside a team of dedicated scientists and researchers, fostering a collaborative and intellectually stimulating atmosphere. We offer continuous professional development, access to advanced technologies, and a clear career path for growth within the organisation. Be part of a company that is committed to improving lives through scientific excellence and innovation.
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