740 Pharmaceutical Development jobs in the United Kingdom
Pharmaceutical Development Chemist
Posted 20 days ago
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Principal Formulation Scientist - Pharmaceutical Development
Posted 3 days ago
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Responsibilities:
- Lead the formulation development of new chemical entities (NCEs) and complex dosage forms (e.g., oral solids, injectables, topical).
- Design and execute formulation studies, including pre-formulation, excipient compatibility, stability testing, and process development.
- Characterize drug substances and drug products using a range of analytical techniques.
- Develop and optimize manufacturing processes for pilot and commercial scale-up.
- Troubleshoot formulation and manufacturing issues, providing scientific expertise and solutions.
- Collaborate effectively with cross-functional teams, including analytical development, DMPK, regulatory affairs, and manufacturing.
- Author and review technical reports, development protocols, and regulatory submission documents.
- Stay abreast of scientific advancements, emerging technologies, and industry trends in pharmaceutical formulation and drug delivery.
- Mentor junior scientists and contribute to the scientific advancement and technical capabilities of the formulation department.
- Ensure all activities are conducted in compliance with GMP and relevant regulatory guidelines.
- PhD or Master's degree in Pharmaceutical Sciences, Pharmaceutics, Chemistry, Chemical Engineering, or a related field.
- Minimum of 8 years of hands-on experience in pharmaceutical formulation development within the industry.
- Proven track record in developing robust and scalable formulations for various dosage forms.
- In-depth knowledge of drug delivery principles, excipient science, and material characterization techniques.
- Experience with analytical techniques such as HPLC, DSC, TGA, XRPD, and dissolution testing.
- Familiarity with GMP requirements and regulatory guidelines (e.g., FDA, EMA).
- Strong understanding of process development and scale-up principles.
- Excellent analytical, problem-solving, and critical thinking skills.
- Superb written and verbal communication skills, with the ability to present complex scientific data clearly.
- Demonstrated leadership capabilities and the ability to manage multiple projects simultaneously.
Senior Formulation Scientist - Pharmaceutical Development
Posted 3 days ago
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Key Responsibilities:
- Design and develop innovative pharmaceutical formulations for various therapeutic areas.
- Conduct pre-formulation studies, including material characterization and stability assessments.
- Optimize existing formulations to improve efficacy, safety, and patient compliance.
- Oversee the preparation of preclinical batches and support in vivo studies.
- Troubleshoot formulation-related issues and implement effective solutions.
- Collaborate with analytical teams to develop and validate analytical methods for formulation characterization.
- Mentor and guide junior scientists in formulation development techniques and best practices.
- Prepare detailed technical reports, development summaries, and contribute to regulatory filings.
- Stay current with scientific literature, industry trends, and regulatory requirements relevant to pharmaceutical formulation.
- Manage project timelines and resources effectively to ensure timely project completion.
- Ph.D. or M.S. in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related discipline.
- Minimum of 5-7 years of progressive experience in pharmaceutical formulation development.
- Extensive knowledge of various dosage forms (e.g., tablets, capsules, injectables, sustained-release systems).
- Hands-on experience with formulation development equipment and techniques.
- Proficiency in statistical analysis and experimental design (DoE).
- Strong understanding of physical chemistry, material science, and drug delivery principles.
- Excellent written and verbal communication skills, with the ability to present complex data clearly.
- Proven project management skills and ability to lead scientific projects.
- Experience with regulatory guidelines (e.g., FDA, EMA) related to drug development.
- Ability to work effectively in a collaborative, multi-disciplinary team environment.
Senior Formulation Scientist - Pharmaceutical Development
Posted 4 days ago
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Key Responsibilities:
- Lead the development of new drug product formulations (e.g., tablets, capsules, injectables) from early-stage feasibility through to technology transfer.
- Design and execute formulation development studies, including pre-formulation, excipient compatibility, and stability testing.
- Characterize drug substances and formulated products using a range of analytical techniques (e.g., HPLC, dissolution testing, physical property analysis).
- Optimize formulations to achieve desired pharmacokinetic profiles, stability, and manufacturability.
- Troubleshoot formulation and process-related issues, providing expert scientific input.
- Prepare technical reports, development summaries, and relevant documentation for regulatory submissions.
- Collaborate closely with cross-functional teams, including analytical development, process development, manufacturing, and regulatory affairs.
- Evaluate and implement new formulation technologies and methodologies.
- Mentor junior scientists and contribute to the growth of the formulation development team.
Required Qualifications and Experience:
- MSc or PhD in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related discipline.
- Minimum of 5-7 years of experience in pharmaceutical formulation development, preferably within the pharmaceutical industry.
- Proven experience with oral solid dosage forms (tablets, capsules) and/or parenteral formulations.
- Hands-on experience with common pharmaceutical formulation equipment and analytical instruments.
- Strong understanding of drug delivery principles, pharmacokinetics, and product performance.
- Knowledge of GMP guidelines and regulatory requirements (e.g., FDA, EMA) for drug product development.
- Excellent problem-solving, analytical, and critical thinking skills.
- Strong written and oral communication skills, with the ability to present complex scientific information clearly.
- Ability to work independently and as part of a team in a fast-paced environment.
This hybrid role based in **Reading** offers an exciting opportunity to contribute to the development of life-changing medicines.
Senior Formulation Scientist - Pharmaceutical Development
Posted 10 days ago
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Responsibilities:
- Design, develop, and optimize pharmaceutical formulations for small molecules and/or biologics.
- Conduct pre-formulation studies, including solubility, stability, and compatibility assessments.
- Develop prototypes and perform formulation screening to identify optimal drug delivery systems.
- Execute and interpret stability studies according to ICH guidelines.
- Troubleshoot formulation-related issues and propose viable solutions.
- Collaborate with analytical development teams to define testing methods and specifications.
- Support scale-up activities and technology transfer to manufacturing.
- Prepare technical reports, development summaries, and regulatory documentation.
- Stay current with advancements in formulation science and drug delivery technologies.
- PhD or Master's degree in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related discipline.
- Significant experience in pharmaceutical formulation development, ideally within a GMP environment.
- Proven expertise in the development of specific dosage forms (e.g., tablets, capsules, injectables).
- Strong understanding of drug delivery principles, excipient functionality, and manufacturing processes.
- Familiarity with ICH guidelines and regulatory requirements for drug product development.
- Excellent analytical, problem-solving, and experimental design skills.
- Proficiency in relevant laboratory equipment and analytical techniques.
- Strong written and verbal communication skills.
Senior Pharmaceutical Development Scientist - Formulation
Posted 7 days ago
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Job Description
Responsibilities:
- Lead the formulation development of small molecules and/or biologics for various dosage forms (e.g., oral, injectable, topical), ensuring stability, bioavailability, and manufacturability.
- Design and execute experimental studies to investigate drug-excipient compatibility, solubility enhancement, and drug delivery mechanisms.
- Utilise DoE (Design of Experiments) principles to efficiently optimise formulation parameters and manufacturing processes.
- Develop and validate analytical methods for characterising formulated products and assessing drug release profiles.
- Troubleshoot formulation challenges and provide innovative solutions to overcome development hurdles.
- Collaborate closely with pre-clinical, clinical, analytical, and manufacturing sciences teams to ensure seamless project progression.
- Prepare comprehensive technical reports, development summaries, and regulatory submission documents.
- Stay abreast of the latest scientific literature, technological advancements, and regulatory guidelines in pharmaceutical formulation.
- Mentor junior scientists and contribute to a culture of scientific excellence and continuous learning.
- Manage multiple development projects concurrently, ensuring adherence to timelines and budgets in a remote setting.
- Contribute to intellectual property generation and patent applications related to novel formulations.
- Evaluate and implement new formulation technologies and platforms.
- Communicate effectively with internal stakeholders and external partners regarding project status and technical findings.
- A Master's degree or PhD in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related discipline.
- A minimum of 5-7 years of hands-on experience in pharmaceutical formulation development.
- Proven expertise in developing various dosage forms and understanding of their associated manufacturing processes.
- Strong knowledge of drug delivery systems, material science, and analytical techniques relevant to formulation characterisation.
- Experience with analytical instrumentation (e.g., HPLC, dissolution apparatus, DSC, TGA) is essential.
- Proficiency in statistical analysis software and DoE methodologies.
- Excellent problem-solving abilities and a systematic approach to experimental design and data interpretation.
- Strong written and verbal communication skills, with the ability to present complex scientific information clearly and concisely.
- Ability to work independently and collaboratively in a remote environment, demonstrating strong organisational and time management skills.
- Familiarity with regulatory requirements (e.g., ICH guidelines, FDA, EMA) pertaining to drug product development.
- Experience with biologics formulation is a significant plus.
Principal Pharmaceutical Development Scientist (Formulation)
Posted 18 days ago
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Job Description
Key Responsibilities:
- Lead the formulation development of new chemical entities (NCEs) and existing products, focusing on oral solid dosage forms (tablets, capsules).
- Design and execute pre-formulation studies, including physicochemical characterization, solubility enhancement techniques, and excipient compatibility.
- Develop robust, scalable, and manufacturable formulations, optimizing for dissolution, bioavailability, and stability.
- Plan and conduct pre-clinical and clinical formulation trials, ensuring timely delivery of materials.
- Troubleshoot formulation challenges and investigate root causes for product performance issues.
- Utilize advanced analytical techniques (e.g., HPLC, dissolution testing, DSC, TGA, XRPD) to characterize drug substances and formulated products.
- Collaborate closely with analytical development, process chemistry, manufacturing sciences, and regulatory affairs teams to ensure seamless project progression.
- Prepare comprehensive development reports, CMC documentation for regulatory submissions (IND, NDA), and present findings to internal and external stakeholders.
- Stay abreast of the latest advancements in pharmaceutical formulation, drug delivery technologies, and relevant scientific literature.
- Mentor and guide junior scientists, fostering a culture of scientific excellence and innovation.
- Contribute to strategic decision-making regarding drug development pipeline prioritization and technology platform selection.
- Ensure all activities are conducted in compliance with GMP and relevant regulatory guidelines.
- PhD in Pharmaceutics, Pharmaceutical Sciences, Chemistry, or a related discipline.
- A minimum of 10 years of hands-on experience in pharmaceutical formulation development, with a strong emphasis on solid dosage forms.
- Proven expertise in pre-formulation, formulation design, process development, and scale-up.
- In-depth knowledge of excipient science, drug-excipient interactions, and various drug delivery technologies.
- Experience with Good Manufacturing Practices (GMP) and regulatory guidelines (FDA, EMA).
- Proficiency in analytical techniques for characterization of drug substances and products.
- Excellent problem-solving skills and a systematic approach to experimental design and data analysis.
- Strong leadership, communication, and interpersonal skills, with the ability to influence and collaborate effectively across functions.
- Demonstrated ability to manage multiple projects and prioritize effectively.
- Experience with patent literature and intellectual property considerations is desirable.
- Must be eligible to work in the UK.
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Senior Pharmaceutical Development Scientist (Formulation)
Posted 20 days ago
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About the Role:
The Senior Pharmaceutical Development Scientist will be responsible for the design, development, and optimization of drug product formulations across various dosage forms. You will play a critical role in pre-formulation studies, formulation development, stability testing, and scale-up activities, contributing to the successful progression of drug candidates through the development pipeline. The ideal candidate will possess strong scientific expertise in pharmaceutics, excellent analytical skills, and a deep understanding of regulatory requirements.
Key Responsibilities:
- Design and execute pre-formulation studies to characterise active pharmaceutical ingredients (APIs) and excipients.
- Develop and optimize formulations for various dosage forms, including oral solid dosage forms (tablets, capsules), semi-solids, and liquids.
- Plan and conduct stability studies according to ICH guidelines and relevant regulatory expectations.
- Perform analytical testing to support formulation development, including dissolution testing, content uniformity, and impurity profiling.
- Collaborate with analytical development teams to establish appropriate analytical methods.
- Support technology transfer activities and the scale-up of manufacturing processes from lab to pilot and commercial scales.
- Troubleshoot formulation-related issues and propose scientifically sound solutions.
- Prepare technical reports, development summaries, and regulatory submission documents (e.g., IND, NDA sections).
- Stay abreast of scientific literature, new technologies, and industry trends in pharmaceutics and drug delivery.
- Work closely with cross-functional teams, including pre-clinical, clinical, regulatory affairs, and manufacturing.
- Mentor junior scientists and contribute to a culture of scientific excellence and innovation.
- Ensure all laboratory activities are conducted in compliance with Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) principles.
- Ph.D. or Master's degree in Pharmaceutics, Pharmaceutical Sciences, Chemistry, or a related discipline.
- A minimum of 5-7 years of relevant experience in pharmaceutical formulation development within the pharmaceutical industry.
- Proven track record in developing and characterizing various dosage forms.
- Strong understanding of physicochemical principles, drug delivery systems, and material science.
- Hands-on experience with formulation development equipment and analytical instrumentation.
- Knowledge of ICH guidelines and regulatory requirements for drug product development.
- Excellent problem-solving, analytical, and critical thinking skills.
- Strong written and verbal communication skills, with the ability to document scientific findings clearly and concisely.
- Ability to work independently and collaboratively in a fast-paced, team-oriented environment.
- Experience with statistical analysis and design of experiments (DoE) is a plus.
Senior Pharmaceutical Development Scientist
Posted today
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Senior Pharmaceutical Development Scientist
Posted 1 day ago
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Job Description
Responsibilities:
- Lead the formulation development of new drug products, from pre-clinical through to early clinical stages.
- Design and execute experiments to characterize drug substances and optimize formulations, ensuring stability, bioavailability, and manufacturability.
- Develop and validate analytical methods for assessing drug product quality and performance.
- Troubleshoot formulation-related issues and provide scientific expertise to manufacturing and regulatory teams.
- Interpret experimental data, draw scientifically sound conclusions, and prepare comprehensive reports for internal review and regulatory submissions.
- Stay abreast of the latest scientific literature, industry trends, and regulatory guidelines relevant to pharmaceutical development.
- Collaborate effectively with cross-functional teams, including medicinal chemists, process engineers, quality assurance, and regulatory affairs, in a remote setting.
- Contribute to the development of intellectual property and strategic research planning.
- Mentor junior scientists and contribute to a culture of scientific excellence and continuous improvement.
- Ensure all research activities comply with company policies, ethical standards, and regulatory requirements (e.g., GMP).
- Ph.D. or M.S. in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related field.
- Minimum of 5 years of experience in pharmaceutical formulation development, with a strong understanding of drug delivery systems.
- Proven experience in designing and conducting formulation studies for various dosage forms (e.g., oral, injectable, topical).
- Proficiency in relevant analytical techniques (e.g., HPLC, GC, dissolution testing, DSC).
- Excellent understanding of physicochemical properties of drugs and their impact on formulation.
- Strong knowledge of regulatory requirements (e.g., ICH guidelines, GMP) for drug development.
- Exceptional problem-solving, analytical, and critical thinking skills.
- Effective written and verbal communication skills, with the ability to present complex data clearly.
- Demonstrated ability to work independently and collaboratively within a remote team environment.
- Experience with pre-formulation studies and excipient selection is highly desirable.