1,812 Pharmacologist jobs in the United Kingdom

Clinical Pharmacologist (Remote)

L1 8JU Liverpool, North West £65000 Annually WhatJobs

Posted 11 days ago

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full-time
Our client, a leading pharmaceutical research organization, is seeking a highly qualified Clinical Pharmacologist to join their innovative and entirely remote team. This role is crucial for the design, execution, and interpretation of clinical pharmacology studies that inform drug development and optimization. You will be responsible for developing study protocols, overseeing data collection, and analyzing pharmacokinetic and pharmacodynamic data to understand drug behavior in humans. This position requires a deep understanding of drug metabolism, drug interactions, and dose-response relationships. You will collaborate closely with clinical investigators, statisticians, regulatory affairs specialists, and other scientists across the organization to ensure studies are conducted to the highest scientific and ethical standards. Key responsibilities include contributing to regulatory submissions, evaluating emerging drug candidates, and advising on optimal dosing strategies. Experience with various analytical techniques and biostatistical methods applied to clinical pharmacology data is essential. This role demands excellent analytical, problem-solving, and scientific writing skills. You will be expected to stay abreast of the latest advancements in clinical pharmacology, pharmacogenetics, and relevant therapeutic areas. As a remote-first position, you will leverage digital collaboration tools to effectively communicate and contribute to a global team. The ability to interpret complex scientific data and present findings clearly and concisely to both scientific and non-scientific audiences is paramount. We are looking for a self-directed, detail-oriented professional with a passion for advancing medical science through rigorous pharmacological research. This is an exceptional opportunity to contribute to the development of life-changing medicines within a flexible and supportive remote working environment.

Key Responsibilities:
  • Design and develop clinical pharmacology study protocols.
  • Oversee the execution of clinical pharmacology studies.
  • Analyze pharmacokinetic (PK) and pharmacodynamic (PD) data.
  • Interpret study results and assess drug behavior in human subjects.
  • Contribute to the development of optimal dosing regimens.
  • Evaluate drug interactions and potential safety risks.
  • Prepare clinical pharmacology sections for regulatory submissions (e.g., IND, NDA).
  • Collaborate with cross-functional teams including clinical, biostatistics, and regulatory affairs.
  • Stay current with scientific literature and advancements in clinical pharmacology.
  • Contribute to scientific publications and presentations.
Qualifications:
  • PhD or PharmD with a specialization in Pharmacology, Clinical Pharmacology, or a related life science field.
  • Minimum of 5 years of experience in clinical pharmacology in the pharmaceutical industry or academia.
  • Strong understanding of PK/PD principles, drug metabolism, and pharmacogenetics.
  • Experience with clinical trial design and execution.
  • Proficiency in data analysis software (e.g., NONMEM, Phoenix WinNonlin).
  • Excellent scientific writing and communication skills.
  • Ability to work independently and effectively in a remote team environment.
  • Knowledge of regulatory guidelines relevant to drug development.
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Principal Clinical Pharmacologist

SO14 0AA Southampton, South East £85000 Annually WhatJobs

Posted 15 days ago

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full-time
A leading pharmaceutical research and development company is seeking a highly experienced Principal Clinical Pharmacologist to join their innovative, fully remote team. This critical role offers a significant opportunity to influence drug development strategies and contribute to bringing life-changing medicines to patients globally. You will be responsible for the design, execution, and interpretation of clinical pharmacology studies, ensuring robust data generation and contributing to regulatory submissions. The ideal candidate will possess a deep understanding of drug metabolism and pharmacokinetics (DMPK), pharmacodynamics (PD), drug-drug interactions (DDIs), and clinical trial design. This position requires a visionary scientist with strong analytical skills, excellent leadership capabilities, and the ability to thrive in a fast-paced, remote research environment.

Key Responsibilities:
  • Lead the design and development of clinical pharmacology strategies for new drug candidates across various therapeutic areas.
  • Oversee the planning, execution, and analysis of Phase I-III clinical pharmacology studies, including first-in-human trials, dose escalation, and special population studies.
  • Develop and validate bioanalytical methods for drug and metabolite quantification.
  • Interpret complex clinical pharmacology data, including PK, PD, DDI, and drug-induced QT studies.
  • Provide expert guidance on dose selection, regimen optimization, and population PK/PD modeling.
  • Contribute to the preparation of regulatory documents (e.g., INDs, NDAs, CTDs) and interact with regulatory agencies.
  • Collaborate closely with multidisciplinary teams, including clinical operations, biostatistics, regulatory affairs, and project management.
  • Mentor and guide junior clinical pharmacologists and research staff.
  • Stay abreast of the latest scientific advancements, regulatory guidelines, and industry best practices in clinical pharmacology.
  • Publish research findings in peer-reviewed journals and present at scientific conferences.
  • Ensure compliance with Good Clinical Practice (GCP) and other relevant regulations.
  • Contribute to the strategic direction of the company's drug development pipeline.
Qualifications and Skills:
  • Ph.D. or Pharm.D. with significant postdoctoral training in Pharmacology, Clinical Pharmacology, Pharmaceutical Sciences, or a related discipline.
  • Minimum of 8-10 years of progressive experience in clinical pharmacology within the pharmaceutical industry or a related research setting.
  • Extensive experience in designing and conducting early-stage clinical trials and analyzing clinical pharmacology data.
  • In-depth knowledge of PK/PD principles, DMPK, DDI assessment, and drug safety.
  • Proficiency with clinical pharmacology data analysis software (e.g., NONMEM, Phoenix WinNonlin).
  • Experience with regulatory requirements and submission processes (FDA, EMA).
  • Strong leadership, communication, and interpersonal skills, with the ability to influence cross-functional teams.
  • Proven track record of scientific contributions, including publications and presentations.
  • Demonstrated ability to work independently and collaboratively in a remote, global team environment.
  • Experience in specific therapeutic areas (e.g., oncology, infectious diseases) is a plus.
This is a pivotal role for an experienced pharmacologist looking to make a substantial impact on drug development within a fully remote framework. We offer a highly competitive salary, comprehensive benefits, and the opportunity to work on cutting-edge pharmaceutical research.
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Principal Clinical Pharmacologist

PL1 1DN Plymouth, South West £90000 Annually WhatJobs

Posted 19 days ago

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full-time
Our client is seeking a highly accomplished Principal Clinical Pharmacologist to join their cutting-edge pharmaceutical research division. This is a key leadership position within a fully remote team, dedicated to advancing the understanding and application of pharmacological principles in drug development. You will play a critical role in designing, overseeing, and interpreting clinical pharmacology studies, ensuring the safe and effective use of novel therapeutics. Your expertise will guide the transition of compounds from pre-clinical development through to market approval.

Primary Responsibilities:
  • Lead the strategic planning and execution of clinical pharmacology programs, including study design, protocol development, and data analysis.
  • Provide expert interpretation of PK/PD data, safety assessments, and therapeutic dose selection.
  • Contribute to regulatory submissions (e.g., IND, NDA) by authoring relevant sections and engaging with health authorities.
  • Collaborate closely with internal teams (e.g., clinical operations, biostatistics, regulatory affairs) and external partners (e.g., CROs, investigators).
  • Mentor and develop junior clinical pharmacologists and contribute to scientific thought leadership within the company.
  • Ensure compliance with GCP, regulatory guidelines, and company SOPs across all clinical pharmacology activities.
  • Evaluate and implement novel methodologies and technologies to enhance clinical pharmacology studies.
  • Present findings at scientific conferences and contribute to peer-reviewed publications.

Essential Qualifications: A PhD or MD with extensive post-doctoral experience (minimum 10 years) in clinical pharmacology, pharmacokinetics, or a related discipline is required. A strong track record of successfully leading clinical pharmacology studies in the pharmaceutical industry, with a deep understanding of drug metabolism, pharmacogenomics, and therapeutic drug monitoring, is essential. Expertise in regulatory requirements and experience interacting with global health authorities (e.g., FDA, EMA) is critical. The ability to think strategically, solve complex problems, and communicate effectively, both verbally and in writing, is paramount. Given the fully remote nature of this role, candidates must possess exceptional self-management skills, a proactive approach, and a proven ability to work collaboratively and productively within a distributed team structure. A dedicated home office setup with high-speed internet is necessary. This exciting opportunity is based remotely, supporting operations in Plymouth, Devon, UK .
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Senior Clinical Pharmacologist (Remote)

L1 8JQ Liverpool, North West £75000 Annually WhatJobs

Posted 3 days ago

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Job Description

full-time
Our client, a pioneering global pharmaceutical company, is seeking a highly qualified Senior Clinical Pharmacologist to join their innovative research and development team on a fully remote basis. This crucial role involves designing, executing, and analyzing clinical pharmacology studies to support the development of novel therapeutics, all managed from your home office. You will be instrumental in defining the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of investigational drugs, ensuring their safety and efficacy in human subjects. The ideal candidate will possess deep expertise in clinical pharmacology, drug metabolism, and pharmacokinetic/pharmacodynamic (PK/PD) modeling. Your responsibilities will include developing study protocols, overseeing data collection and analysis, and interpreting study results to guide clinical development decisions. You will collaborate closely with cross-functional teams, including clinical operations, biostatistics, and regulatory affairs, to ensure the successful progression of drug candidates through the development pipeline. Experience with NONMEM or other population PK/PD modeling software is essential. This is an outstanding opportunity to contribute to cutting-edge pharmaceutical research and development while enjoying the benefits of a remote work arrangement. We are looking for a scientific leader with strong analytical skills, excellent written and verbal communication abilities, and a comprehensive understanding of drug discovery and development processes. Your contributions will directly shape the future of medicine and improve patient outcomes.
Responsibilities:
  • Design, develop, and execute clinical pharmacology studies.
  • Analyze pharmacokinetic (PK) and pharmacodynamic (PD) data.
  • Develop and apply population PK/PD models to characterize drug behavior.
  • Interpret study results and provide recommendations for clinical development strategies.
  • Collaborate with clinical teams, biostatisticians, and regulatory affairs.
  • Prepare study protocols, analysis plans, and clinical study reports.
  • Ensure compliance with regulatory guidelines and ethical standards.
  • Stay abreast of scientific literature and advancements in clinical pharmacology.
  • Mentor junior scientists and contribute to team development.
Qualifications:
  • PhD or PharmD in Pharmacology, Pharmaceutical Sciences, or a related discipline.
  • Minimum of 7 years of experience in clinical pharmacology within the pharmaceutical industry.
  • Extensive experience in designing and conducting Phase I-IV clinical pharmacology studies.
  • Proficiency in population PK/PD modeling software (e.g., NONMEM, Phoenix WinNonlin).
  • Strong understanding of drug metabolism, drug interactions, and bioanalytical methods.
  • Excellent scientific writing and presentation skills.
  • Ability to work independently and collaboratively in a remote environment.
  • Knowledge of regulatory requirements (FDA, EMA) related to drug development.
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Pharmaceutical Research Scientist

CB2 0AL Cambridge, Eastern £40000 Annually WhatJobs

Posted 4 days ago

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full-time
Our client, a pioneering pharmaceutical company, is seeking a talented Pharmaceutical Research Scientist to contribute to groundbreaking drug discovery and development programs. This role offers a dynamic hybrid working environment, combining essential laboratory work with analytical and data interpretation tasks that can be conducted remotely. You will play a key role in designing and executing experiments, analysing complex biological data, and contributing to the advancement of novel therapeutics. The ideal candidate will possess a strong academic background in a relevant scientific discipline, excellent laboratory skills, and a passion for innovation in the pharmaceutical industry. You will be joining a world-class research team focused on improving patient outcomes.

Key Responsibilities:
  • Design, conduct, and optimise in vitro and in vivo experiments to evaluate drug candidates.
  • Analyse and interpret experimental data, employing statistical methods and relevant software.
  • Contribute to the development of new assays and research methodologies.
  • Collaborate closely with cross-functional teams, including medicinal chemists, pharmacologists, and toxicologists.
  • Prepare detailed scientific reports, presentations, and publications.
  • Maintain accurate and comprehensive laboratory notebooks and records.
  • Ensure compliance with all relevant safety regulations and laboratory protocols.
  • Stay abreast of the latest scientific literature and technological advancements in the field.
  • Assist in the troubleshooting of experimental procedures and equipment.
  • Present research findings at internal meetings and external scientific conferences.
  • Contribute to intellectual property generation and patent filings.
  • Mentor junior research staff and provide technical guidance.

Qualifications:
  • Ph.D. or Master's degree in Pharmacology, Biochemistry, Molecular Biology, or a related life science discipline.
  • Proven experience in pharmaceutical research and drug discovery.
  • Hands-on experience with relevant laboratory techniques (e.g., cell culture, PCR, ELISA, chromatography).
  • Strong understanding of drug development processes and regulatory requirements.
  • Proficiency in data analysis software (e.g., GraphPad Prism, R, SPSS).
  • Excellent written and verbal communication skills, with a strong publication record or potential.
  • Ability to work independently and collaboratively in a team-oriented environment.
  • Strong problem-solving skills and a meticulous attention to detail.
  • Experience in a specific therapeutic area (e.g., oncology, immunology) is a plus.
  • Familiarity with biostatistics and experimental design principles.
Join our innovative team and contribute to the future of medicine from **Cambridge, Cambridgeshire, UK**.
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Pharmaceutical Research Scientist

ST1 1AA Staffordshire, West Midlands £55000 Annually WhatJobs

Posted 4 days ago

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full-time
Our client, a renowned pharmaceutical company, is looking for a dedicated Pharmaceutical Research Scientist to join their innovative R&D team. This role is based in our laboratory facilities in **Stoke-on-Trent, Staffordshire, UK**, and requires a hands-on approach. You will play a crucial role in the discovery and development of novel therapeutic agents. Responsibilities include designing and executing complex experiments, synthesizing and characterizing potential drug candidates, and analyzing biological and chemical data. You will be involved in all stages of the drug discovery pipeline, from target identification to preclinical evaluation. The ideal candidate will hold a Ph.D. or Master's degree in Chemistry, Pharmacology, Biochemistry, or a related life science discipline, with a strong academic record and practical laboratory experience. Proven expertise in medicinal chemistry, organic synthesis, or drug metabolism and pharmacokinetics (DMPK) is highly desirable. Experience with standard laboratory techniques, analytical instrumentation (e.g., HPLC, NMR, Mass Spectrometry), and data analysis software is essential. You must possess excellent problem-solving skills, meticulous attention to detail, and the ability to work independently and collaboratively within a multidisciplinary team. Strong written and verbal communication skills are required for documenting research findings and presenting results to scientific colleagues. This is an exciting opportunity to contribute to cutting-edge pharmaceutical research and development, working in a state-of-the-art facility. You will be part of a dynamic team focused on bringing life-changing medicines to patients. We are committed to fostering a culture of scientific excellence and continuous learning, providing ample opportunities for professional growth. The successful candidate will demonstrate a passion for scientific discovery and a commitment to advancing human health. Attention to safety protocols and regulatory compliance is paramount in this role. We offer a competitive salary and benefits package for the right candidate.
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Pharmaceutical Research Scientist

NR1 1BH Norwich, Eastern £60000 Annually WhatJobs

Posted 5 days ago

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full-time
Our client, a leading pharmaceutical company, is seeking a talented and innovative Pharmaceutical Research Scientist to join their state-of-the-art research facility in Norwich, Norfolk, UK . This role is central to driving forward groundbreaking research and development in novel therapeutic areas. The successful candidate will be responsible for designing and executing complex experiments, analyzing data, and contributing to the development of new drug candidates. This position offers an exciting opportunity to work within a collaborative scientific environment, contributing to significant advancements in healthcare.

Key responsibilities include:
  • Designing, planning, and executing in-vitro and in-vivo experiments to support drug discovery and development programs.
  • Developing and validating new assays and methodologies.
  • Collecting, analyzing, and interpreting experimental data, and generating comprehensive reports.
  • Collaborating closely with cross-functional teams, including medicinal chemists, biologists, and toxicologists.
  • Maintaining detailed laboratory notebooks and adhering to Good Laboratory Practices (GLP).
  • Troubleshooting experimental procedures and resolving technical challenges.
  • Presenting research findings at internal meetings and potentially external scientific conferences.
  • Staying abreast of the latest scientific literature and technological advancements in the field.
  • Contributing to patent applications and regulatory submissions.

The ideal candidate will possess a PhD in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline, with a strong track record of research achievements. Hands-on experience in relevant experimental techniques (e.g., cell culture, molecular cloning, protein analysis, small animal models) is essential. Excellent analytical, problem-solving, and communication skills are crucial for success in this role. Experience in a pharmaceutical or biotechnology industry setting is highly desirable. This is a laboratory-based role requiring a strong commitment to scientific rigor and innovation.

Qualifications:
  • PhD in Pharmacology, Molecular Biology, Biochemistry, or a related life science field.
  • Proven experience in designing and conducting complex research experiments.
  • Expertise in relevant scientific techniques and methodologies.
  • Strong data analysis and interpretation skills.
  • Excellent written and verbal communication skills.
  • Ability to work independently and collaboratively in a team environment.
  • Experience with pharmaceutical R&D is a plus.
  • Commitment to maintaining high scientific standards.
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Pharmaceutical Research Scientist

ST1 1AA Staffordshire, West Midlands £55000 Annually WhatJobs

Posted 8 days ago

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full-time
Our client, a pioneering pharmaceutical company, is seeking a dedicated Pharmaceutical Research Scientist to join their innovative R&D team in Stoke-on-Trent, Staffordshire, UK . This crucial role involves conducting cutting-edge research to develop novel therapeutics and enhance existing drug formulations. You will work in state-of-the-art laboratory facilities, contributing to projects that have a significant impact on patient health worldwide. The ideal candidate will possess a strong scientific background, a meticulous approach to research, and a passion for drug discovery and development. This is an on-site position, essential for laboratory-based activities.

Key Responsibilities:
  • Design and execute complex experiments to investigate biological pathways and drug mechanisms.
  • Analyze experimental data using advanced statistical methods and interpret results.
  • Develop and validate new analytical methods and protocols.
  • Contribute to the writing of research reports, scientific publications, and regulatory submissions.
  • Collaborate with cross-functional teams, including chemists, biologists, and clinicians.
  • Maintain accurate and detailed laboratory records and documentation.
  • Stay abreast of the latest scientific literature and technological advancements in the pharmaceutical field.
  • Ensure compliance with all laboratory safety regulations and company policies.
  • Present research findings at internal meetings and external scientific conferences.
  • Contribute to the intellectual property strategy of the company.

Qualifications:
  • Ph.D. or Master's degree in Pharmacology, Biochemistry, Molecular Biology, Chemistry, or a related life science discipline.
  • Proven experience in pharmaceutical research and drug discovery.
  • Strong practical skills in relevant laboratory techniques (e.g., cell culture, PCR, Western blotting, chromatography).
  • Proficiency in data analysis software (e.g., GraphPad Prism, R) is highly desirable.
  • Excellent problem-solving abilities and critical thinking skills.
  • Strong scientific writing and presentation skills.
  • Ability to work independently and as part of a collaborative research team.
  • Detail-oriented with a commitment to scientific rigor and accuracy.
  • Experience in a specific therapeutic area (e.g., oncology, immunology) is a plus.

This is an on-site role located in Stoke-on-Trent, Staffordshire, UK . Our client offers a challenging and rewarding career path within a leading pharmaceutical organization.
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Pharmaceutical Research Scientist

BS1 4 Bristol, South West £45000 Annually WhatJobs

Posted 10 days ago

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full-time
Our client, a leading pharmaceutical company, is seeking a dedicated and innovative Pharmaceutical Research Scientist to join their cutting-edge R&D team based in Bristol, South West England, UK . This role is crucial in advancing drug discovery and development projects, involving hands-on laboratory work, data analysis, and contributing to scientific publications. You will be involved in experimental design, execution of complex assays, and interpretation of results to support the identification and validation of novel therapeutic targets. A strong scientific background, meticulous attention to detail, and a passion for pharmaceutical research are essential.

Key Responsibilities:
  • Design, execute, and optimize experiments related to drug discovery and development.
  • Perform a variety of laboratory techniques and assays, including biochemical, cell-based, and molecular biology assays.
  • Analyze and interpret experimental data, drawing meaningful conclusions and proposing next steps.
  • Contribute to the development and validation of new assay methodologies.
  • Maintain accurate and detailed laboratory notebooks and records.
  • Collaborate effectively with a multidisciplinary team of scientists, chemists, and clinicians.
  • Prepare scientific reports, presentations, and contribute to manuscript writing for publications and patents.
  • Stay abreast of the latest scientific literature, technologies, and trends in the pharmaceutical industry.
  • Troubleshoot experimental issues and propose solutions to ensure project progression.
  • Ensure adherence to all laboratory safety protocols and regulatory guidelines.

The ideal candidate will hold a PhD or Master's degree in a relevant life science discipline (e.g., Pharmacology, Biochemistry, Molecular Biology, Medicinal Chemistry). Proven experience in pharmaceutical research or a related biotech setting is required, with a strong track record of experimental design and data analysis. Expertise in specific areas relevant to drug discovery (e.g., assay development, in vitro pharmacology, small molecule screening) is highly desirable. Excellent analytical, problem-solving, and critical thinking skills are essential. Strong written and verbal communication skills, with the ability to present complex scientific information clearly, are a must. The ability to work both independently and collaboratively within a team environment is key. This role requires a blend of on-site laboratory work and potential for remote data analysis/reporting, making it a hybrid position based out of our Bristol facility.
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Pharmaceutical Research Scientist

BT2 7JD Belfast, Northern Ireland £55000 Annually WhatJobs

Posted 10 days ago

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full-time
Our client, a cutting-edge pharmaceutical research company, is seeking a highly skilled Pharmaceutical Research Scientist to join their innovative and fully remote R&D team. This position offers an exceptional opportunity to contribute to the discovery and development of novel therapeutics. You will conduct advanced scientific research, design and execute experiments, analyze complex data sets, and contribute to the preparation of research reports and publications. This role is 100% remote, requiring a self-motivated individual with excellent scientific rigor and communication skills. You will collaborate closely with a global team of scientists, clinicians, and project managers, utilizing state-of-the-art virtual collaboration tools. The ideal candidate will possess a PhD in Pharmacology, Biochemistry, Molecular Biology, or a related life science discipline, coupled with significant post-doctoral or industry research experience. Expertise in drug discovery processes, assay development, molecular biology techniques, or computational drug design would be highly advantageous. You will be expected to troubleshoot experiments, interpret results, and propose new research directions. This is a chance to be at the forefront of pharmaceutical innovation, working on challenging projects with the potential to significantly impact patient health. The flexibility of this remote role allows for optimal work-life integration while maintaining high scientific productivity.
Key Responsibilities:
  • Conduct independent scientific research in drug discovery and development.
  • Design, optimize, and execute experiments using relevant biological and chemical assays.
  • Analyze and interpret complex experimental data, drawing sound conclusions.
  • Develop and validate novel research methodologies and techniques.
  • Prepare high-quality research reports, manuscripts for publication, and presentations.
  • Collaborate effectively with cross-functional research teams in a remote setting.
  • Stay abreast of the latest scientific literature and technological advancements in the field.
  • Troubleshoot experimental challenges and propose solutions.
  • Contribute to the intellectual property strategy of the company.
  • Mentor junior research staff and interns as needed.
Qualifications:
  • PhD in Pharmacology, Biochemistry, Molecular Biology, Medicinal Chemistry, or a related discipline.
  • Proven track record of scientific research with publications in reputable peer-reviewed journals.
  • Extensive experience in drug discovery or pharmaceutical R&D.
  • Expertise in relevant scientific techniques (e.g., cell culture, molecular biology, protein chemistry, high-throughput screening).
  • Strong analytical and data interpretation skills.
  • Excellent written and verbal communication skills for effective remote collaboration.
  • Ability to work independently, manage multiple projects, and meet deadlines.
  • Proficiency in scientific software and data analysis tools.
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