206 Principal Investigator jobs in the United Kingdom

Principal Investigator (PI)

Doncaster, Yorkshire and the Humber Clerkenwell Health

Posted 8 days ago

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Job Description

Who are we?

Clerkenwell Health is an innovative and leading Research Organisation specialising in the delivery of scientifically grounded Clinical Trials using its collaborative Contract Research Organisation, extensive Site Network and leading Therapy Development Programme. We focus on supporting Mental Health and CNS research, with particular expertise in psychedelic drug development.


The role

We are seeking an experienced Principal Investigator (PI) to lead the medical oversight and delivery of psychedelic-assisted psychotherapy clinical trials. The post holder will play a critical leadership role in ensuring the highest standards of clinical and research integrity, regulatory compliance, and participant care throughout the study lifecycle.


What will the role entail?

  • Serve as the Principal Investigator on psychedelic clinical trials, fulfilling all responsibilities outlined under ICH-GCP, including governance, oversight, pharmacovigilance, and reporting.
  • Promote and ensure adherence to Good Clinical Practice (GCP) and all protocol requirements across trial operations.
  • Oversee the medical and psychiatric evaluation of participants at screening, dosing, and follow-up stages; manage referrals to GP or specialist services as needed.
  • Ensure full protocol compliance during trial procedures; identify and document any deviations appropriately.
  • Accurately report serious adverse events (SAEs) and adverse events (AEs) to the trial sponsor and Chief Investigator.
  • Supervise and mentor clinical staff involved in study-specific assessments and procedures.
  • Provide clinical leadership, training, and ongoing mentorship to trial staff to uphold GCP and protocol standards.
  • Foster a positive and collaborative team environment within Clerkenwell Health and with external stakeholders.
  • Ensure accurate and complete documentation in source notes and clinical trial case report forms (CRFs).
  • Oversee the use, storage, dispensing, and accountability of Investigational Medicinal Products (IMP) and non-IMPs.
  • Monitor and review the completion of psychometric and structured interview assessments conducted with trial participants.
  • Maintain current knowledge of psychedelic-assisted therapies, relevant clinical protocols, and therapeutic innovations.


What will you need?

  • To be able to travel to Doncaster at least once a week
  • Medical degree (e.g., MBBS, MD)
  • GMC full registration with licence to practise
  • MRCPsych, MRCP, or equivalent medical college membership
  • Previous Experience as a Principal Investigator (PI)
  • Experience in mental health or CNS therapeutic areas would be advantageous
  • In-depth knowledge of clinical research regulations (FDA, EMA, MHRA), ICH-GCP guidelines, and local/international laws
  • Excellent communication and interpersonal skills for liaising with sponsors, CROs, and site teams
  • Familiarity with ethical research conduct, informed consent, and IRB/Ethics Committee review processes
  • Sound risk management and safety practices
  • Experience with rating tools such as MINI, CAPS-5, and C-SSRS


What will the process be?

An initial screening call with the recruiter followed by a 2 stage interview process over Teams.


Is This the Role for You?

At Clerkenwell Health, our core values are Compassion, Collaboration, Innovation , and Integrity . If you're passionate about improving mental health outcomes through research and ready to take a lead role in pioneering psychedelic-assisted therapies - we’d love to hear from you.

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Principal Digital Forensic Investigator

Manchester, North West £50000 - £60000 Annually Alexander Associates

Posted 1 day ago

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Job Description

permanent

Are you a seasoned digital forensics professional ready to take on challenging and impactful investigations? Do you thrive in an environment where every day brings a new case, new technology, and new insights? If so, we want to hear from you.

We’re currently recruiting on behalf of a leading digital forensics organisation that is seeking a Principal Digital Forensic Investigator to join their expert team. This is a unique opportunity to be part of a dynamic and forward-thinking company that places innovation, professional growth, and collaboration at the core of everything it does.

Please note: This role is not suitable for recent graduates. A minimum of 7 years of industry experience in digital forensics (public or private sector) is required.

The Role

As a Principal Digital Forensic Investigator, you will play a critical role in identifying, acquiring, analysing, and presenting electronic evidence across a wide range of devices and cases. From criminal investigations to civil litigation, your findings will have real-world implications, supporting justice and organisational security.

You’ll be based in a cutting-edge ISO 17025 accredited forensic laboratory, with occasional travel and on-site work when required.

Security Clearance Requirements

Due to the nature of this work, NPPV3 and SC (Security Check) clearance are mandatory.
To be eligible, you must be a British National and have resided in the UK for at least 5 years. Exceptions may apply for overseas service with HM Government.

Key Responsibilities

  • Conduct forensic acquisition, analysis, and reporting on digital evidence (computers, mobile devices, etc.).
  • Ensure chain-of-custody and evidential integrity is maintained throughout investigations.
  • Use tools like EnCase, FTK, X-Ways, NUIX, Magnet Axiom, Cellebrite UFED, MSAB XRY.
  • Compile comprehensive technical reports suitable for court.
  • Provide clear and professional expert witness testimony.
  • Collaborate with law enforcement and legal professionals.
  • Mentor junior team members and participate in ongoing technical development.
  • Support eDiscovery and Cyber Security services as needed.
  • Uphold high standards in security, documentation, and quality assurance.

Ideal Candidate Profile

  • 7+ years hands-on experience in digital forensics investigations.
  • Proven knowledge of forensic principles, ISO 17025, and ACPO guidelines.
  • Intermediate-level training in one or more major forensic software platforms.
  • Strong analytical and problem-solving abilities.
  • Excellent report writing and verbal communication skills.
  • Experience working under pressure with attention to detail.
  • Willingness to occasionally work outside normal hours or travel as required.

Benefits & Perks

  • Flexible Working Options
  • Company Pension Scheme (3% employer contribution)
  • 24 Days Annual Leave + Bank Holidays
  • Holiday Loyalty Bonus (Up to 30 days after 3 years)
  • Birthday Day Off
  • MediCash Cash Plan
  • Life Insurance (Death in Service)
  • Annual Media Subscription Package (Netflix, Amazon Prime, Spotify, etc.)
This advertiser has chosen not to accept applicants from your region.

Principal Digital Forensic Investigator

Leicester, East Midlands £50000 - £60000 Annually Alexander Associates

Posted 1 day ago

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Job Description

permanent

Are you a seasoned digital forensics professional ready to take on challenging and impactful investigations? Do you thrive in an environment where every day brings a new case, new technology, and new insights? If so, we want to hear from you.

We’re currently recruiting on behalf of a leading digital forensics organisation that is seeking a Principal Digital Forensic Investigator to join their expert team. This is a unique opportunity to be part of a dynamic and forward-thinking company that places innovation, professional growth, and collaboration at the core of everything it does.

Please note: This role is not suitable for recent graduates. A minimum of 7 years of industry experience in digital forensics (public or private sector) is required.

The Role

As a Principal Digital Forensic Investigator, you will play a critical role in identifying, acquiring, analysing, and presenting electronic evidence across a wide range of devices and cases. From criminal investigations to civil litigation, your findings will have real-world implications, supporting justice and organisational security.

You’ll be based in a cutting-edge ISO 17025 accredited forensic laboratory, with occasional travel and on-site work when required.

Security Clearance Requirements

Due to the nature of this work, NPPV3 and SC (Security Check) clearance are mandatory.
To be eligible, you must be a British National and have resided in the UK for at least 5 years. Exceptions may apply for overseas service with HM Government.

Key Responsibilities

  • Conduct forensic acquisition, analysis, and reporting on digital evidence (computers, mobile devices, etc.).
  • Ensure chain-of-custody and evidential integrity is maintained throughout investigations.
  • Use tools like EnCase, FTK, X-Ways, NUIX, Magnet Axiom, Cellebrite UFED, MSAB XRY.
  • Compile comprehensive technical reports suitable for court.
  • Provide clear and professional expert witness testimony.
  • Collaborate with law enforcement and legal professionals.
  • Mentor junior team members and participate in ongoing technical development.
  • Support eDiscovery and Cyber Security services as needed.
  • Uphold high standards in security, documentation, and quality assurance.

Ideal Candidate Profile

  • 7+ years hands-on experience in digital forensics investigations.
  • Proven knowledge of forensic principles, ISO 17025, and ACPO guidelines.
  • Intermediate-level training in one or more major forensic software platforms.
  • Strong analytical and problem-solving abilities.
  • Excellent report writing and verbal communication skills.
  • Experience working under pressure with attention to detail.
  • Willingness to occasionally work outside normal hours or travel as required.

Benefits & Perks

  • Flexible Working Options
  • Company Pension Scheme (3% employer contribution)
  • 24 Days Annual Leave + Bank Holidays
  • Holiday Loyalty Bonus (Up to 30 days after 3 years)
  • Birthday Day Off
  • MediCash Cash Plan
  • Life Insurance (Death in Service)
  • Annual Media Subscription Package (Netflix, Amazon Prime, Spotify, etc.)
This advertiser has chosen not to accept applicants from your region.

Principal Digital Forensic Investigator

M1 Ancoats, North West Alexander Associates

Posted 4 days ago

Job Viewed

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Job Description

full time

Are you a seasoned digital forensics professional ready to take on challenging and impactful investigations? Do you thrive in an environment where every day brings a new case, new technology, and new insights? If so, we want to hear from you.

We’re currently recruiting on behalf of a leading digital forensics organisation that is seeking a Principal Digital Forensic Investigator to join their expert team. This is a unique opportunity to be part of a dynamic and forward-thinking company that places innovation, professional growth, and collaboration at the core of everything it does.

Please note: This role is not suitable for recent graduates. A minimum of 7 years of industry experience in digital forensics (public or private sector) is required.

The Role

As a Principal Digital Forensic Investigator, you will play a critical role in identifying, acquiring, analysing, and presenting electronic evidence across a wide range of devices and cases. From criminal investigations to civil litigation, your findings will have real-world implications, supporting justice and organisational security.

You’ll be based in a cutting-edge ISO 17025 accredited forensic laboratory, with occasional travel and on-site work when required.

Security Clearance Requirements

Due to the nature of this work, NPPV3 and SC (Security Check) clearance are mandatory.
To be eligible, you must be a British National and have resided in the UK for at least 5 years. Exceptions may apply for overseas service with HM Government.

Key Responsibilities

  • Conduct forensic acquisition, analysis, and reporting on digital evidence (computers, mobile devices, etc.).
  • Ensure chain-of-custody and evidential integrity is maintained throughout investigations.
  • Use tools like EnCase, FTK, X-Ways, NUIX, Magnet Axiom, Cellebrite UFED, MSAB XRY.
  • Compile comprehensive technical reports suitable for court.
  • Provide clear and professional expert witness testimony.
  • Collaborate with law enforcement and legal professionals.
  • Mentor junior team members and participate in ongoing technical development.
  • Support eDiscovery and Cyber Security services as needed.
  • Uphold high standards in security, documentation, and quality assurance.

Ideal Candidate Profile

  • 7+ years hands-on experience in digital forensics investigations.
  • Proven knowledge of forensic principles, ISO 17025, and ACPO guidelines.
  • Intermediate-level training in one or more major forensic software platforms.
  • Strong analytical and problem-solving abilities.
  • Excellent report writing and verbal communication skills.
  • Experience working under pressure with attention to detail.
  • Willingness to occasionally work outside normal hours or travel as required.

Benefits & Perks

  • Flexible Working Options
  • Company Pension Scheme (3% employer contribution)
  • 24 Days Annual Leave + Bank Holidays
  • Holiday Loyalty Bonus (Up to 30 days after 3 years)
  • Birthday Day Off
  • MediCash Cash Plan
  • Life Insurance (Death in Service)
  • Annual Media Subscription Package (Netflix, Amazon Prime, Spotify, etc.)
This advertiser has chosen not to accept applicants from your region.

Principal Digital Forensic Investigator

LE1 Leicester, East Midlands Alexander Associates

Posted 4 days ago

Job Viewed

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Job Description

full time

Are you a seasoned digital forensics professional ready to take on challenging and impactful investigations? Do you thrive in an environment where every day brings a new case, new technology, and new insights? If so, we want to hear from you.

We’re currently recruiting on behalf of a leading digital forensics organisation that is seeking a Principal Digital Forensic Investigator to join their expert team. This is a unique opportunity to be part of a dynamic and forward-thinking company that places innovation, professional growth, and collaboration at the core of everything it does.

Please note: This role is not suitable for recent graduates. A minimum of 7 years of industry experience in digital forensics (public or private sector) is required.

The Role

As a Principal Digital Forensic Investigator, you will play a critical role in identifying, acquiring, analysing, and presenting electronic evidence across a wide range of devices and cases. From criminal investigations to civil litigation, your findings will have real-world implications, supporting justice and organisational security.

You’ll be based in a cutting-edge ISO 17025 accredited forensic laboratory, with occasional travel and on-site work when required.

Security Clearance Requirements

Due to the nature of this work, NPPV3 and SC (Security Check) clearance are mandatory.
To be eligible, you must be a British National and have resided in the UK for at least 5 years. Exceptions may apply for overseas service with HM Government.

Key Responsibilities

  • Conduct forensic acquisition, analysis, and reporting on digital evidence (computers, mobile devices, etc.).
  • Ensure chain-of-custody and evidential integrity is maintained throughout investigations.
  • Use tools like EnCase, FTK, X-Ways, NUIX, Magnet Axiom, Cellebrite UFED, MSAB XRY.
  • Compile comprehensive technical reports suitable for court.
  • Provide clear and professional expert witness testimony.
  • Collaborate with law enforcement and legal professionals.
  • Mentor junior team members and participate in ongoing technical development.
  • Support eDiscovery and Cyber Security services as needed.
  • Uphold high standards in security, documentation, and quality assurance.

Ideal Candidate Profile

  • 7+ years hands-on experience in digital forensics investigations.
  • Proven knowledge of forensic principles, ISO 17025, and ACPO guidelines.
  • Intermediate-level training in one or more major forensic software platforms.
  • Strong analytical and problem-solving abilities.
  • Excellent report writing and verbal communication skills.
  • Experience working under pressure with attention to detail.
  • Willingness to occasionally work outside normal hours or travel as required.

Benefits & Perks

  • Flexible Working Options
  • Company Pension Scheme (3% employer contribution)
  • 24 Days Annual Leave + Bank Holidays
  • Holiday Loyalty Bonus (Up to 30 days after 3 years)
  • Birthday Day Off
  • MediCash Cash Plan
  • Life Insurance (Death in Service)
  • Annual Media Subscription Package (Netflix, Amazon Prime, Spotify, etc.)
This advertiser has chosen not to accept applicants from your region.

Principal Digital Forensic Investigator

Manchester, North West Alexander Associates Technical Recruitment

Posted 7 days ago

Job Viewed

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Job Description

permanent

Are you a seasoned digital forensics professional ready to take on challenging and impactful investigations? Do you thrive in an environment where every day brings a new case, new technology, and new insights? If so, we want to hear from you.

We're currently recruiting on behalf of a leading digital forensics organisation that is seeking a Principal Digital Forensic Investigator to join their exper.


This advertiser has chosen not to accept applicants from your region.

Project Lead

Oxfordshire, South East £72000 - £82000 Annually PDQ Engineering Recruitment & Training Services Lt

Posted today

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Job Description

permanent

Your current Job title could be:-

Project managerOR Program managerOR project LeadOR project Leader OR Project Planning manager OR Project Planning LeadOR Programme leadOR Head of ProjectsOR Principal project engineer

Scientific Instrumentation company

FULL Details available to suitable candidates

Open to British/EU & ILR candidates - No Sponsorship Available.

This advertiser has chosen not to accept applicants from your region.
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Project Lead

South East, South East You Recruitment

Posted 1 day ago

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Job Description

contract

Project Lead 18-Month FTC

Kent

We're working with a leading manufacturing business looking for a hands-on Project Lead to deliver medium-to-large capital projects with minimal disruption to operations.

Key Responsibilities:

Manage a team of engineers and specialists from proposal and budgeting, through design and installation, to training and commissioning of project concepts

Lead the delivery of capital projects across a live production environment, ensuring minimal operational impact

Coordinate suppliers, budgets, schedules, and on-site work

Ensure Health & Safety compliance from design through to implementation

Supervise contractor activity and engage cross-functional teams

Collaborate closely with internal departments and purchasing to define project scope and ensure contractual compliance

What You'll Need:

Proven experience managing capital projects in industrial/manufacturing environments

Strong leadership and stakeholder engagement skills

Knowledge across civil, mechanical, electrical, and controls systems

Proactive, well-organised, and safety-conscious approach to work

Project Management qualification

Health and Safety Qualification

Apply now to (url removed)

This advertiser has chosen not to accept applicants from your region.

Project Lead

Coventry, West Midlands Futura Design

Posted 1 day ago

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Job Description

contract

Our OEM Client based in Coventry, is searching for a Project Lead to join their team, Inside IR35. This is a contract position until 31st March 2026.

Umbrella Pay Rate: £27.03 per hour.

The role is for a project leader with a background in support of cross-functional projects with multi-stakeholder requirements.

The primary purpose of the role within Research is to support the collaborative R&D strategy development, planning and delivery of collaborative R&D projects working cross-functionally with partner organisations in industry and academia and leveraging government funding to accelerate and scale up R&D projects.

Duties:

  • High degree of numeracy, attention to detail. 
  • Planning and co-ordination of work across multiple projects to meet deadlines.
  • High level of organisational skills.
  • Effective communication across internal cross functional teams and external customer facing.

Experience Required:

  • Previous work experience within a business planning / project management office environment.
  • Proficient in use of Microsoft Office applications, especially Excel, previous use of enterprise systems (e.g. SAP).
  • Cross-functional working - planning own work and responsive to support requests.
  • Self-motivated and able to operate with low supervision.
  • Preparation of formal documentation to prescribed standards.
  • Control and management of confidential information including GDPR compliance.

Desirable Experience Requested:

  • Previously worked in/around government funded collaborative R&D projects, e.g. Innovate UK and EU.
  • Previously worked within an accountancy audit / regulated finance framework.
  • Role is based at National Automotive Innovation Centre at University of Warwick (NAIC).
  • Parking permit included for University of Warwick managed carparks.
  • Some occasional travel to our other client sites may be required.
  • Some hybrid work arrangements possible for remote/home working.
This advertiser has chosen not to accept applicants from your region.

Project Lead

Derbyshire, East Midlands Alexander Mann Solutions - Contingency

Posted 1 day ago

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Job Description

contract

AMS is a global workforce solutions partner committed to creating inclusive, dynamic, and future-ready workplaces. We help organisations adapt, grow, and thrive in an ever-evolving world by building, shaping, and optimising diverse talent strategies.

Our Contingent Workforce Solution (CWS) is one way we support our clients. Acting as an extension of their recruitment teams, we connect them with skilled interim and temporary professionals, fostering workplaces where everyone can contribute and succeed.

On behalf of our globally respected client who develop cutting-edge technologies that deliver clean, safe and competitive solutions to meet the planet's vital power needs we are looking for a Project Lead for a 12 month contract based in Derby (3 days per week on site, 2 days remote working).

As a Project Lead, your primary responsibilities will include:

  • Accountable for the successful delivery to cost, specification & time for defined
    projects/workstreams.
  • Establish, develop & maintain Project Management processes & documentation
    necessary to deliver projects (e.g., schedules, WBS, performance reports, budgets,
    risk registers, resource plans etc.).
  • Support management and key stakeholders in decision making.
  • Develop & implement Project Management best practice.
  • Provide guidance & tutoring to colleagues on Project Management systems, tools
    & methods.

Key skills required for the Project Lead role:

  • Degree level qualification preferable or equivalent industry experience.
  • Member of a professional body and working towards a APMPQ qualification or
    equivalent.
  • Significant experience gained in previous project management role (Project Lead)
    or experience gained within a relevant discipline, preferably on project work
    (Project Controller).
  • Desirable to have a familiarisation with enterprise project management systems
    and tools, such as Primavera P6 and Business Map.

Next steps

We will only accept workers operating via an Umbrella or PAYE engagement model.

If you are interested in applying for the Project Lead position and meet the criteria outlined above, please click the link to apply and we will contact you with an update in due course.


AMS, a Recruitment Process Outsourcing Company, may in the delivery of some of its services be deemed to operate as an Employment Agency or an Employment Business

This advertiser has chosen not to accept applicants from your region.
 

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