6,518 Senior Research Scientist jobs in the United Kingdom

Principal Scientific Research Scientist (Biotechnology)

NE1 4XN Newcastle upon Tyne, North East £75000 Annually WhatJobs

Posted 11 days ago

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full-time
Our client, a globally recognized leader in scientific research and development, is seeking an exceptional Principal Scientific Research Scientist to join their state-of-the-art facility in Newcastle upon Tyne, Tyne and Wear, UK . This senior role is critical for driving innovation and leading research initiatives in the field of biotechnology, specifically focusing on novel therapeutic development. The successful candidate will possess a deep understanding of molecular biology, genetics, and advanced drug discovery techniques, coupled with a proven ability to lead research teams and secure funding. You will be responsible for conceptualizing, designing, and executing complex research projects from inception to potential clinical application.

Key Responsibilities:
  • Lead the design and execution of ambitious research projects in biotechnology, with a focus on developing novel therapeutics for unmet medical needs.
  • Direct and mentor a team of research scientists and technicians, fostering a collaborative and high-performance research environment.
  • Develop and implement innovative experimental strategies using advanced molecular biology, genomics, and proteomics techniques.
  • Critically analyse complex biological data, interpret results, and draw robust conclusions to guide research direction.
  • Contribute to the preparation of grant proposals and secure external funding for research initiatives.
  • Publish findings in high-impact peer-reviewed journals and present research at international conferences.
  • Collaborate effectively with cross-functional teams, including chemistry, pharmacology, and clinical development departments.
  • Ensure compliance with all relevant ethical guidelines, regulatory requirements, and safety protocols within the laboratory.
  • Identify emerging scientific trends and technologies relevant to the company's strategic goals.
  • Contribute to the intellectual property strategy through patent filings and disclosures.

Qualifications and Skills:
  • A Ph.D. in Molecular Biology, Biochemistry, Genetics, Biotechnology, or a closely related life science discipline.
  • A minimum of 10 years of post-doctoral research experience in an academic or industrial R&D setting.
  • A distinguished track record of publications in leading scientific journals and successful grant acquisition.
  • Extensive hands-on experience with advanced techniques such as CRISPR-Cas9, next-generation sequencing (NGS), mammalian cell culture, protein expression and purification, and various assay development platforms.
  • Proven experience in leading and managing research projects and scientific teams.
  • Strong understanding of drug discovery and development processes.
  • Exceptional analytical, critical thinking, and problem-solving skills.
  • Excellent written and verbal communication skills, with the ability to present complex scientific information effectively.
  • A strategic mindset with the ability to identify and pursue novel research opportunities.
  • Experience in bioinformatics and computational biology is advantageous.

This is a fantastic opportunity to make a significant impact on the future of medicine within a leading research organization. If you are a visionary scientist ready to lead groundbreaking discoveries, we want to hear from you.
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Senior Scientific Research Scientist - Genomics

LE1 7HQ Leicester, East Midlands £58000 Annually WhatJobs

Posted 13 days ago

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full-time
Join a world-class scientific research and development institution in **Leicester, Leicestershire, UK**, as a Senior Scientific Research Scientist specializing in Genomics. This exciting opportunity sits within a collaborative and innovative environment focused on pushing the boundaries of biological understanding and its applications. You will lead significant research projects, contribute to groundbreaking discoveries, and mentor a team of talented researchers.

Your key responsibilities will include:
  • Designing and implementing advanced genomic research projects, including Next-Generation Sequencing (NGS) experiments.
  • Developing and optimizing protocols for DNA/RNA extraction, library preparation, and sequencing.
  • Analyzing large-scale genomic datasets using bioinformatics tools and statistical methods.
  • Interpreting genomic data to identify disease markers, understand biological pathways, and drive therapeutic insights.
  • Managing and maintaining genomic research infrastructure, including sequencing platforms and bioinformatics pipelines.
  • Collaborating with internal and external research groups to foster new scientific partnerships.
  • Preparing high-impact research publications for peer-reviewed journals and presenting findings at scientific conferences.
  • Mentoring and providing technical guidance to junior scientists and research assistants.
  • Ensuring strict adherence to all laboratory safety protocols and ethical guidelines.
  • Contributing to the development of grant proposals and securing research funding.
We are seeking individuals with a Ph.D. in Genomics, Molecular Biology, Bioinformatics, or a closely related field. A minimum of 5 years of post-doctoral or industry research experience focused on genomics is essential, supported by a strong publication record. Expertise in NGS technologies (e.g., Illumina, PacBio), library preparation techniques, and a variety of sequencing applications (e.g., WGS, WES, RNA-Seq, ChIP-Seq) is required. Proficiency in bioinformatics analysis tools, programming languages (e.g., Python, R), and statistical software is crucial. Experience with data visualization and interpretation of complex genomic datasets is highly desirable. Excellent analytical, problem-solving, and critical thinking skills are a must. Outstanding written and verbal communication abilities, with experience in presenting scientific findings, are essential. The ability to lead research projects, manage multiple priorities, and foster a collaborative team environment is vital. If you are a passionate and experienced genomics researcher looking for a challenging and impactful role, we encourage you to apply.
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Senior Scientific Research Scientist - Genomics

MK14 6GD Milton Keynes, South East £65000 Annually WhatJobs

Posted 18 days ago

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full-time
Our client is seeking a highly motivated and experienced Senior Scientific Research Scientist specializing in Genomics for a fully remote, permanent position. This role offers an exceptional opportunity to contribute to groundbreaking research from the convenience of your home office, with a focus on advancing our understanding of complex biological systems. You will be integral to the research and development efforts of our client, contributing to projects that push the boundaries of scientific discovery. While working remotely, your insights and expertise will be critical to the success of research based in the Milton Keynes, Buckinghamshire, UK area and extending globally.

Your responsibilities will include designing and conducting complex experiments, analyzing large-scale genomic datasets, and developing innovative research methodologies. You will play a key role in interpreting experimental results, contributing to scientific publications, and presenting findings at conferences. Collaboration is key, and you will work closely with a multidisciplinary team of scientists, bioinformaticians, and clinicians, sharing knowledge and expertise effectively. Staying abreast of the latest advancements in genomics, molecular biology, and bioinformatics is essential.

The ideal candidate will possess a PhD in Genomics, Molecular Biology, Genetics, or a related field, with a strong publication record and extensive experience in experimental design and data analysis. Proven expertise in various genomic technologies (e.g., NGS, qPCR, microarrays) and bioinformatics tools is required. Excellent critical thinking, problem-solving skills, and the ability to manage multiple research projects simultaneously are paramount. Exceptional communication and collaboration skills are necessary to thrive in this remote research environment.

Qualifications:
  • PhD in Genomics, Molecular Biology, Genetics, or a related life science discipline.
  • Minimum of 5 years of post-doctoral research experience or equivalent industry experience.
  • Extensive hands-on experience with Next-Generation Sequencing (NGS) technologies and associated workflows.
  • Proficiency in bioinformatics tools and software for genomic data analysis (e.g., R, Python, Bioconductor).
  • Strong understanding of molecular biology techniques and genetic principles.
  • Proven ability to design, execute, and interpret complex scientific experiments.
  • Excellent analytical and problem-solving skills.
  • Strong publication record in reputable peer-reviewed journals.
  • Excellent written and verbal communication skills for scientific reporting and presentations.
  • Ability to work independently and as a collaborative member of a remote research team.
This is a prime opportunity for a driven scientist to make a significant impact on the field of genomics in a flexible, remote-first setting.
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Principal Scientific Research Scientist - Biologics

B1 1HL Birmingham, West Midlands £85000 Annually WhatJobs

Posted 20 days ago

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full-time
Our client, a leading biopharmaceutical company, is seeking an exceptional Principal Scientific Research Scientist with expertise in Biologics to join their innovative R&D department in Birmingham, West Midlands, UK . This senior role involves leading groundbreaking research projects focused on the discovery and development of novel biologic therapeutics. You will be responsible for designing and executing complex experiments, interpreting data, authoring publications, and guiding a team of talented scientists. This position is critical for advancing our pipeline and driving scientific innovation.

Key Responsibilities:
  • Lead independent research projects focused on the discovery and development of biologic drugs (e.g., antibodies, proteins, vaccines).
  • Design, optimize, and perform complex in vitro and in vivo experiments.
  • Analyze and interpret large datasets, employing advanced statistical methods.
  • Develop and implement novel assays and technologies for biological research.
  • Author high-impact publications in peer-reviewed journals and present findings at international conferences.
  • Mentor and guide junior research scientists and postdoctoral fellows.
  • Collaborate effectively with cross-functional teams, including medicinal chemistry, pharmacology, and clinical development.
  • Contribute to intellectual property generation and patent applications.
  • Ensure adherence to all laboratory safety regulations and ethical guidelines.
  • Manage research budgets and resources effectively.
  • Stay abreast of the latest scientific advancements and competitive landscape in biologics research.

Qualifications:
  • PhD in Molecular Biology, Immunology, Biochemistry, or a related life science discipline.
  • Minimum of 8 years of post-doctoral research experience in the biopharmaceutical industry or equivalent academic setting, with a strong focus on biologics.
  • Demonstrated track record of successfully leading research projects and delivering impactful scientific outcomes.
  • Extensive hands-on experience with a wide range of molecular and cellular biology techniques relevant to biologics development.
  • Proven expertise in assay development, validation, and characterization of biologic molecules.
  • Excellent scientific writing and presentation skills.
  • Strong leadership, mentorship, and team collaboration abilities.
  • Proficiency in data analysis software (e.g., GraphPad Prism, R).
  • Experience with bioinformatics tools is a plus.
  • Strong understanding of drug discovery and development processes.

This demanding role requires on-site presence at our state-of-the-art research facilities in Birmingham, West Midlands, UK , to foster intensive collaboration and hands-on experimentation. Our client offers a stimulating research environment, competitive compensation, and opportunities for significant career advancement.
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Principal Scientific Research Scientist (Biotechnology)

PO2 1AA Portsmouth, South East £70000 Annually WhatJobs

Posted 20 days ago

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full-time
Our client is seeking an accomplished and innovative Principal Scientific Research Scientist to join their pioneering team in a fully remote capacity. This is a unique opportunity for a highly experienced researcher to drive significant advancements in biotechnology and scientific innovation from anywhere. You will be responsible for leading complex research projects, designing and executing cutting-edge experiments, and contributing to the development of novel scientific solutions. The ideal candidate will possess deep expertise in a relevant area of biotechnology, such as molecular biology, genetic engineering, bioprocessing, or drug development. Responsibilities include conceptualizing research strategies, developing and validating new methodologies, analyzing and interpreting complex data, and preparing scientific publications and reports. You will collaborate closely with a global team of scientists and researchers, sharing knowledge and driving collaborative innovation. Experience in leading research teams, securing grants, and managing research projects from inception to completion is highly desirable. A proven track record of scientific achievement, including publications in high-impact journals and patents, is essential. Strong analytical, problem-solving, and communication skills are paramount for success in this remote, collaborative environment. A PhD in a relevant life science discipline (e.g., Biology, Biochemistry, Molecular Biology, Biotechnology), along with extensive post-doctoral and industry research experience, is required. If you are a visionary scientist eager to push the boundaries of biotechnology and contribute to impactful scientific discoveries remotely, we encourage you to apply.

Key Responsibilities:
  • Lead and direct scientific research projects in biotechnology.
  • Design and execute complex experiments and develop novel research methodologies.
  • Analyze and interpret sophisticated scientific data to derive meaningful conclusions.
  • Contribute to the development of new products, processes, or therapeutic solutions.
  • Author scientific manuscripts, patents, and research reports.
  • Collaborate with a global network of scientists and research partners.
  • Mentor and guide junior researchers, fostering scientific excellence.
  • Stay abreast of the latest scientific advancements and emerging technologies.

Qualifications:
  • PhD in a relevant life science discipline (e.g., Biology, Biochemistry, Molecular Biology, Biotechnology).
  • Minimum of 8 years of post-doctoral and industry research experience in biotechnology.
  • Proven track record of scientific innovation and achievement, including publications and/or patents.
  • Expertise in a specialized area of biotechnology (e.g., molecular biology, genetics, cell biology).
  • Strong experience in experimental design, data analysis, and scientific writing.
  • Demonstrated leadership skills and experience in managing research projects.
  • Excellent communication, collaboration, and problem-solving abilities.
  • Ability to work effectively and autonomously in a remote research environment.
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Senior Scientific Research Scientist - Remote

RG1 2NN Reading, South East £55000 Annually WhatJobs

Posted 20 days ago

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full-time
Our client is seeking an accomplished Senior Scientific Research Scientist to join their innovative R&D department. This hybrid role offers the flexibility to work both remotely and from their state-of-the-art facility located in **Reading, Berkshire, UK**. You will be instrumental in driving forward groundbreaking research initiatives, contributing to the design and execution of experimental protocols, and analyzing complex data sets to generate actionable insights. The ideal candidate possesses a Ph.D. in a relevant scientific discipline, a strong publication record, and a passion for scientific discovery. You will collaborate closely with a multidisciplinary team of scientists and engineers, both in person and virtually, to translate theoretical concepts into tangible advancements.

Responsibilities:
  • Design, conduct, and interpret complex scientific experiments and research projects within your area of expertise.
  • Develop and refine experimental methodologies, ensuring scientific rigor and reproducibility.
  • Analyze large and complex datasets using advanced statistical and computational techniques.
  • Collaborate with cross-functional teams, including chemists, biologists, physicists, and engineers, to achieve research objectives.
  • Prepare and present research findings through written reports, scientific publications, and oral presentations to internal and external stakeholders.
  • Contribute to the strategic planning and direction of research programs.
  • Maintain detailed and accurate laboratory notebooks and research records.
  • Stay abreast of the latest scientific literature, technological advancements, and emerging trends in relevant fields.
  • Mentor junior researchers and provide technical guidance and support.
  • Ensure compliance with all laboratory safety protocols and ethical guidelines.
  • Contribute to patent applications and intellectual property development.
  • Assist in the procurement and management of laboratory equipment and supplies.
  • Participate in collaborative research initiatives with external partners and academic institutions.
Qualifications:
  • Ph.D. in Chemistry, Biology, Physics, Materials Science, or a related scientific discipline.
  • A minimum of 5 years of post-doctoral or industry research experience, with a strong track record of independent research.
  • Proven experience in experimental design, execution, and data analysis.
  • Demonstrated expertise in relevant scientific techniques and instrumentation.
  • Strong publication record in peer-reviewed scientific journals.
  • Excellent analytical, critical thinking, and problem-solving skills.
  • Proficiency in data analysis software and statistical packages (e.g., R, Python, SPSS).
  • Exceptional written and verbal communication skills, with the ability to clearly articulate complex scientific concepts.
  • Experience working in a hybrid or collaborative team environment, with effective remote communication skills.
  • Ability to manage multiple research projects concurrently and meet deadlines.
  • A proactive, curious, and self-motivated individual with a passion for scientific innovation.
  • Familiarity with intellectual property processes and patent applications is a plus.
  • Experience in (Specific Area relevant to R&D, e.g., gene editing, nanoparticle synthesis, quantum computing) is highly desirable.
This is an exciting opportunity to contribute to cutting-edge research that has the potential to make a real-world impact. You will be joining a dynamic and supportive team, working in a hybrid capacity that balances focused remote work with valuable in-person collaboration in **Reading, Berkshire, UK**. We are committed to fostering an environment of scientific excellence and continuous learning. The successful candidate will be expected to spend a portion of their time at the Reading facility for team meetings, collaborative experiments, and strategic discussions.
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Lead Scientific Research Scientist - Materials Science

PO1 3EZ Portsmouth, South East £85000 Annually WhatJobs

Posted 7 days ago

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full-time
Our client, a prestigious research institution at the forefront of scientific innovation, is seeking an accomplished Lead Scientific Research Scientist specializing in Materials Science. Based at our cutting-edge facility in Portsmouth, Hampshire, UK , this role is integral to driving forward groundbreaking research and development projects. You will lead a team of talented researchers, conceptualize and execute complex experimental programs, and contribute significantly to the advancement of novel materials with diverse applications. This position demands a deep understanding of materials characterization, synthesis, and performance testing, coupled with strong leadership and project management skills.

Responsibilities include designing and managing research projects from conception to completion, securing research grants, and publishing findings in high-impact scientific journals. You will mentor junior scientists, foster a collaborative research environment, and ensure adherence to all safety and ethical guidelines. Expertise in areas such as nanotechnology, polymer science, composite materials, or advanced ceramics is highly desirable. The ideal candidate will hold a PhD in Materials Science, Physics, Chemistry, or a closely related field, with a minimum of 8 years of post-doctoral research experience and a proven track record of leading research initiatives. Exceptional analytical and problem-solving abilities, along with outstanding communication and interpersonal skills, are essential. You should be adept at utilizing advanced analytical instrumentation and possess a strong publication record. This is a unique opportunity to make a substantial contribution to scientific discovery and technological innovation in a stimulating and supportive environment.
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Remote Scientific Research Scientist - Drug Discovery

MK10 0AA Milton Keynes, South East £60000 Annually WhatJobs

Posted 18 days ago

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full-time
Our client, a cutting-edge biotechnology company at the forefront of therapeutic innovation, is seeking a highly motivated and experienced Remote Scientific Research Scientist specializing in Drug Discovery. This is a fully remote position, offering the unique opportunity to contribute to groundbreaking research from your home laboratory or office, collaborating with a world-class team of scientists. You will play a critical role in identifying and validating novel drug targets, designing and conducting experiments, and contributing to the preclinical development of transformative therapies.

Key responsibilities will include:
  • Designing, executing, and interpreting complex experiments to identify and validate novel therapeutic targets.
  • Developing and optimizing assays for screening potential drug candidates.
  • Utilizing advanced molecular and cellular biology techniques to investigate disease mechanisms.
  • Analyzing large datasets using bioinformatics tools and statistical methods to derive meaningful insights.
  • Collaborating closely with computational chemists, medicinal chemists, and pharmacologists to advance drug discovery programs.
  • Keeping abreast of the latest scientific literature and emerging technologies in relevant therapeutic areas.
  • Preparing detailed research reports, scientific presentations, and contributing to the writing of research publications and patent applications.
  • Troubleshooting experimental challenges and developing innovative solutions.
  • Maintaining meticulous laboratory records and ensuring compliance with all relevant safety and ethical guidelines.
  • Contributing to the strategic direction of drug discovery projects and identifying new research opportunities.
  • Participating actively in remote team meetings and contributing to a collaborative research environment.
The ideal candidate will hold a Ph.D. in Molecular Biology, Biochemistry, Pharmacology, or a related life science discipline, with a minimum of 5 years of post-doctoral or industry research experience focused on drug discovery. A proven track record of successfully contributing to preclinical drug development programs is essential. Expertise in key areas such as (mention specific areas like oncology, immunology, neuroscience, small molecule drug discovery, biologics, etc.) is highly desirable. Proficiency in a range of laboratory techniques, including (mention specific techniques like cell culture, protein expression/purification, various assay formats (e.g., ELISA, FRET, AlphaLISA), gene editing, microscopy, etc.), is required. Strong analytical skills, experience with data analysis software (e.g., GraphPad Prism, R, Python), and familiarity with bioinformatics tools are crucial. Excellent written and verbal communication skills, with the ability to articulate complex scientific concepts clearly, are necessary. The ability to work independently, manage multiple research projects concurrently, and thrive in a remote, collaborative setting is paramount. Candidates should be innovative, highly organized, and possess a passion for scientific discovery and advancing human health.
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Research Scientist

Bracknell, South East SRG

Posted today

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Job Title : Research Scientist - Protein

Working Location : Bracknell

Rate : £18.41 per hour

Contract Length : 12 months

Start Date : 19th January 2026


We are looking for a hardworking, motivated individual who is quick to learn and apply themselves to join our dynamic, collaborative and industrious protein production team. This is a one-year contract to support the delivery of a critical protein production process. This role offers the opportunity for the successful candidate to gain hands on experience with an array of downstream processing techniques including protein chromatography and membrane filtration methods.


Role profile and expectations:

  • Work as part of a protein production team to deliver gram quantities of purified recombinant protein to support one of Syngenta’s critical commercial projects
  • Provide hands-on support during this large-scale protein production campaign
  • Learn and conduct the necessary analytical methods to validate final outputs meet defined specifications
  • Accurately record results to agreed company standards
  • Prepare technical reports, present findings within project groups and be an active communicator within the wider Syngenta scientific community
  • Work safely and with due care to others ensuring compliance with company HSE policies


Essential education & experience:

  • Bachelor’s degree in relevant science e.g. Biology, Biochemistry, Biomedical or other similar disciplines
  • Good theoretical understanding of recombinant protein expression
  • Good theoretical understanding of chromatography techniques including affinity, ion exchange (IEX), hydrophobic interaction (HIC) and size exclusion (SEC) chromatography
  • Strong evidence of troubleshooting and innovative problem solving
  • Ability to work independently and as part of a team
  • Good communication and planning skills


Desirable experience:

  • Master’s degree or 1-2 years’ experience working in a laboratory environment
  • 1-2 years lab experience working in any of the core areas highlighted in the above job description
  • Experience with data management tools (e.g. Benchling) and data analysis software (e.g. JMP)
  • Experience of working with scalable bioprocess technologies e.g. TFF, Hollow fibre
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Research Scientist

Oxford, South East Exogene

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Research Scientist

Oxford


About Exogene

At Exogene, we’re reimagining what’s possible in cancer immunotherapy. Our mission is to engineer T-cell receptor therapies that can precisely and powerfully target advanced solid tumours.

To do this, we’ve built a proprietary lab-in-the-loop platform that merges generative AI, biophysical modelling, and high-throughput TCR screening to rapidly design, test, and optimise TCRs with exceptional affinity and specificity. This convergence of computation and wet-lab experimentation allows us to go from concept to candidate molecules in record time.


We’re developing TCR-based trispecific T cell engagers (TCR-TriTCEs)—a new therapeutic modality designed to overcome the unique challenges of the solid tumour microenvironment. This work spans multiple disciplines, from protein engineering and AI-driven design to in vivo validation and translational development.


We are looking for a dynamic research scientist who will help drive the TCR engineering processes and development. The successful candidate will contribute to in vivo and in vitro validation of TCEs. You’ll get involved in purifying recombinant TCRs to perform high-throughput TCR display methods and deep sequencing.


Responsibilities

  • Contribute to in vivo and in vitro validation of TCEs.
  • Collaboratively design and characterise TCRs for proprietary and partnered disease targets.
  • Conduct a suite of protein science operations, including expression, purification, and biophysical analysis.
  • Tackle molecular biology duties: cloning, mutagenesis, DNA isolation, and preparing libraries for deep sequencing.
  • Manage tissue culture assignments, spanning from media prep and cell line care to cryopreservation.
  • Join forces with founders, R&D, academia, and industrial stakeholders to fulfil ambitious R&D objectives.
  • Draft, revise, and oversee repertoire of lab protocols.
  • Offer essential lab support and uphold facility upkeep.


Skills and Qualifications

  • PhD in Immunology, Cell Biology, Biochemistry, or an alike field, paired with at least 1-2 years of relevant lab experience is required.
  • Knowledge of molecular biology protocols, with an emphasis on cloning and PCR is preferred.
  • A background in molecular biology, protein expression, purification and biophysical characterisation is preferred.
  • Experience in cell and immunological assays (flow cytometry, ELISA etc.) is desired.
  • Experience with in vivo and in vitro validation of TCEs (T-cell engagers) in some or all aspects of investigational new drug (IND) approval is desired.
  • Experience TCR engineering is desired.
  • SOP documentation experience is desired.
  • The highest standards in lab precision, record maintenance, and documentation.
  • Excellent written and oral communication skills.


Attributes

  • Self-starter with sound analytical skills, who values scientific integrity and novelty.
  • Collaborative spirit within the lab, open to both giving and receiving actionable feedback.
  • Exceptional at diagnosing and overcoming unforeseen technical challenges.
  • Adept at juggling and prioritising multiple projects to meet deadlines.
  • Versatile and efficient within an interdisciplinary, fast-paced team setup.


What We Offer

  • Market-competitive salary and stock option package.
  • A generous leave policy: 25 days holiday, public holidays, plus a day off for your birthday!
  • Access to fully equipped private lab.
  • Flexibility to work from home as project demands allow.
  • A supportive, cross-disciplinary team fostering a highly collaborative work environment.


How to apply

Launch your journey with Exogene by submitting your CV and a brief cover letter (maximum 400 words) to m.hasan at exogene.co.uk

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