2 Senior Scientists jobs in the United Kingdom

Postdoctoral Scientists

Bionow

Posted today

Job Viewed

Tap Again To Close

Job Description

About The Role
Dr Claus Jorgensen, Group Leader of the Systems Oncology Group, is looking for a Postdoctoral Scientist to join his group. This is a great opportunity for a self-motivated, innovative, meticulous and organised candidate who is keen to work in a dynamic laboratory undertaking cutting edge research.

The goal of the Systems Oncology Group is to understand how the tumour microenvironment, and the desmoplastic reaction, regulates tumour cell function and therapeutic response in pancreatic ductal adenocarcinoma. We have identified a novel target regulating the interactions between tumour cells and the microenvironment, which we believe may be a target for future therapeutic intervention.

The objective of this post is to functionally characterise this target and its role in regulating tumour cells, host cells, and their interactions. Specifically, the post holder will use a number of
in vitro
cell biology assays to assess cell function and biochemical assays to assess cell signalling
in vitro
; this will include functional CRISPR analysis, pharmacological studies, enzyme assays and mass spectrometry analysis in 2D and 3D cell models. Tumour models will be analysed by IF/IHC, proteomics, genomics and transcriptionally as well as testing novel combination treatments using available
in vivo
models (see Hutton et al Cancer Cell 2021, Lee et al Nat Comm 2021 and Below et al Nat Mat This is a project for a highly collaborative individual seeking to make a difference in a very hard to treat cancer.

About You
You should have a PhD in biochemistry, cell biology or a related field. Experience in protein biochemistry, analysis of cell signalling and use of
in vitro
models of cancer is required. Experience with
in vivo
tumour models and immunology is desirable. Key qualities include independent thinking, ability to work in a team and good communication skills, all of which are needed to efficiently work in a multidisciplinary team.

Why choose Cancer Research UK Manchester Institute?
The Cancer Research UK Manchester Institute ), an Institute of The University of Manchester ), is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK ), the largest independent cancer research organisation in the world. In spring 2023 the Institute moved into the new Paterson Building, a £150 million flagship purpose-built biomedical research centre directly attached to The Christie NHS Foundation Trust ), in South Manchester.

We are partnered with The Christie NHS Foundation Trust, one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.

How to apply?
To Apply For This Position Please Visit Our Website

Informal enquiries can be directed to Dr Claus Jorgensen via email:

Closing date: Sunday 26th October 2025

1st round interviews: w.c. 10th November 2025

This advertiser has chosen not to accept applicants from your region.

Research/Senior/Principal Scientists – Celentyx Ltd

Birmingham, West Midlands Celentyx Ltd

Posted 2 days ago

Job Viewed

Tap Again To Close

Job Description

Celentyx Ltd is a successful pharmaceutical research and development company (this position will be based at the Birmingham, UK site), undertaking high-level immune-focussed  in vitro  research using human primary cells and tissues relevant to immuno-oncology, inflammation, neuroinflammation and fibrosis.


As part of our ongoing expansion, we are currently looking for highly motivated, hard-working individuals to join our  in vitro  biology, pathology and pharmacology teams. These teams run a wide range of assays using techniques such as multi-colour (spectral) flow cytometry, high-throughput confocal microscopy, multiplex cytokine assays, 3D- and organotypic culture and RNAseq. Successful applicants will be an integral part of a dynamic and flexible teams that deliver a variety of high-level and often bespoke research to strict timescales.


Prospective candidates should hold a degree in immunology, pharmacology or another relevant subject and for the Senior/Principal Scientist positions, preferably a PhD or equivalent experience. Demonstrated experience and high-level competence (both practical and theoretical) in human cellular and molecular immunology (including an understanding of signalling pathways leading to immune cell responses),  in vitro  immunology (including performing complex assays involving purified immune cells), and multi-parametric flow cytometry are preferred. Experience working with human tissue and/or industrial experience would be an advantage. In addition, excellent organisational skills and the ability to work as part of a team as well as independently are essential.


A generous performance-based remuneration package consisting of salary and bonuses is available. If appropriate, successful candidates will have the opportunity to register for a PhD.


Interested parties should email a current CV and cover letter to 

This advertiser has chosen not to accept applicants from your region.
Be The First To Know

About the latest Senior scientists Jobs in United Kingdom !

 

Nearby Locations

Other Jobs Near Me

Industry

  1. request_quote Accounting
  2. work Administrative
  3. eco Agriculture Forestry
  4. smart_toy AI & Emerging Technologies
  5. school Apprenticeships & Trainee
  6. apartment Architecture
  7. palette Arts & Entertainment
  8. directions_car Automotive
  9. flight_takeoff Aviation
  10. account_balance Banking & Finance
  11. local_florist Beauty & Wellness
  12. restaurant Catering
  13. volunteer_activism Charity & Voluntary
  14. science Chemical Engineering
  15. child_friendly Childcare
  16. foundation Civil Engineering
  17. clean_hands Cleaning & Sanitation
  18. diversity_3 Community & Social Care
  19. construction Construction
  20. brush Creative & Digital
  21. currency_bitcoin Crypto & Blockchain
  22. support_agent Customer Service & Helpdesk
  23. medical_services Dental
  24. medical_services Driving & Transport
  25. medical_services E Commerce & Social Media
  26. school Education & Teaching
  27. electrical_services Electrical Engineering
  28. bolt Energy
  29. local_mall Fmcg
  30. gavel Government & Non Profit
  31. emoji_events Graduate
  32. health_and_safety Healthcare
  33. beach_access Hospitality & Tourism
  34. groups Human Resources
  35. precision_manufacturing Industrial Engineering
  36. security Information Security
  37. handyman Installation & Maintenance
  38. policy Insurance
  39. code IT & Software
  40. gavel Legal
  41. sports_soccer Leisure & Sports
  42. inventory_2 Logistics & Warehousing
  43. supervisor_account Management
  44. supervisor_account Management Consultancy
  45. supervisor_account Manufacturing & Production
  46. campaign Marketing
  47. build Mechanical Engineering
  48. perm_media Media & PR
  49. local_hospital Medical
  50. local_hospital Military & Public Safety
  51. local_hospital Mining
  52. medical_services Nursing
  53. local_gas_station Oil & Gas
  54. biotech Pharmaceutical
  55. checklist_rtl Project Management
  56. shopping_bag Purchasing
  57. home_work Real Estate
  58. person_search Recruitment Consultancy
  59. store Retail
  60. point_of_sale Sales
  61. science Scientific Research & Development
  62. wifi Telecoms
  63. psychology Therapy
  64. pets Veterinary
View All Senior Scientists Jobs