Principal Scientist - Drug Discovery

CB2 1TN Cambridge, Eastern £80000 Annually WhatJobs

Posted 1 day ago

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full-time
Our client, a pioneering pharmaceutical company, is seeking an exceptional Principal Scientist to lead critical drug discovery initiatives within their fully remote research team. This senior position requires a visionary leader with a proven track record in identifying novel therapeutic targets and advancing preclinical candidates. You will be responsible for designing and executing complex research programs, interpreting experimental data, and making key strategic decisions to drive projects forward. The ideal candidate will possess extensive expertise in a relevant therapeutic area, coupled with strong leadership and communication skills to effectively guide multidisciplinary scientific teams. This role offers the unique opportunity to shape the future of medicine from a remote setting, collaborating with world-class researchers across the globe. You will be expected to contribute to the intellectual property portfolio through publications and patent filings, and to present findings at international conferences. The ability to work autonomously, manage resources efficiently, and inspire innovation is paramount for success in this role.

Responsibilities:
  • Lead and manage cutting-edge drug discovery projects from target identification through to preclinical development.
  • Design and oversee the execution of complex experimental strategies.
  • Analyze and interpret complex biological data, drawing robust conclusions.
  • Develop and implement innovative approaches to address challenging scientific problems.
  • Mentor and guide junior scientists, fostering a collaborative and high-performing team environment.
  • Contribute to the strategic direction of the company's research pipeline.
  • Prepare high-quality manuscripts for publication in peer-reviewed journals.
  • Present research findings at scientific conferences and to internal stakeholders.
  • Manage external collaborations with academic institutions and CROs.
  • Contribute to the development of intellectual property, including patent applications.

Qualifications:
  • Ph.D. in Molecular Biology, Pharmacology, Biochemistry, or a related life science discipline.
  • 10+ years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
  • Demonstrated success in leading drug discovery programs and advancing candidates into clinical development.
  • Deep scientific expertise in a specific therapeutic area (e.g., oncology, immunology, neuroscience).
  • Strong knowledge of various drug discovery technologies and methodologies.
  • Exceptional leadership, project management, and communication skills.
  • Proven ability to work independently and collaboratively in a remote, global setting.
  • Excellent track record of scientific publications and presentations.
This is a highly influential role based in Cambridge, Cambridgeshire, UK , offering the flexibility of full remote work, allowing you to contribute significantly to life-changing therapies from anywhere.
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Senior Research Scientist - Drug Discovery

CB22 3AB Cambridge, Eastern £65000 Annually WhatJobs

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full-time
Our client is seeking an accomplished Senior Research Scientist to join a dynamic drug discovery team based in Cambridge, Cambridgeshire, UK . This role is pivotal in advancing novel therapeutic targets from early discovery through to preclinical development. The successful candidate will be responsible for designing, executing, and analyzing complex experiments to identify and validate new drug candidates. Key responsibilities include leading independent research projects, contributing to strategic pipeline decisions, mentoring junior scientists, and collaborating across multidisciplinary teams. You will be expected to stay abreast of the latest scientific literature and technological advancements in your field, presenting findings at internal meetings and potentially at international conferences. The ideal candidate will possess a PhD in a relevant biological science (e.g., Molecular Biology, Pharmacology, Biochemistry) with a strong publication record and at least 5 years of post-doctoral or industry experience. Demonstrated experience in assay development, cell-based assays, in vivo models, and a deep understanding of disease biology relevant to oncology or immunology is highly desirable. Excellent communication, problem-solving, and data interpretation skills are essential. This is an exciting opportunity to make a significant impact on the development of life-changing medicines in a collaborative and innovative environment. The role involves a hybrid working model, offering flexibility between working from home and in our state-of-the-art laboratory facilities in Cambridge . Applicants must be authorized to work in the UK. We are committed to fostering a diverse and inclusive workplace where all employees feel valued and empowered. Join us and contribute to the future of pharmaceutical innovation. Your expertise will be crucial in navigating the challenges of drug discovery and translating scientific breakthroughs into tangible patient benefits. We offer a competitive compensation package, comprehensive benefits, and opportunities for professional growth and development within a leading research organisation.
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Principal Research Scientist (Drug Discovery)

CB2 0AH Cambridge, Eastern £75000 Annually WhatJobs

Posted 1 day ago

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full-time
Our client, a groundbreaking biotechnology firm based in the vibrant scientific hub of Cambridge, Cambridgeshire, UK , is seeking a highly accomplished Principal Research Scientist to spearhead innovative drug discovery initiatives. This is a unique opportunity to join a world-class research team dedicated to developing novel therapeutics for unmet medical needs. You will play a crucial role in designing and executing complex research projects, leading a team of scientists, and contributing to the strategic direction of our client's discovery pipeline. Your expertise will be vital in identifying and validating new drug targets, developing innovative assays, and advancing drug candidates through the early stages of discovery. The ideal candidate will possess a deep understanding of molecular biology, biochemistry, pharmacology, or a related discipline, with a proven track record of significant contributions to drug discovery. You will be adept at troubleshooting complex experimental challenges, interpreting intricate data sets, and communicating findings effectively to both scientific and non-scientific audiences. This hybrid role offers a balance of on-site laboratory work and remote engagement with research data and collaborative teams. You will be responsible for mentoring junior scientists, fostering a collaborative and innovative research environment, and staying abreast of the latest scientific advancements in the field. Experience with cutting-edge technologies such as high-throughput screening, CRISPR, or advanced imaging techniques is highly desirable. This role offers a chance to make a profound impact on patient lives through groundbreaking scientific research and development.

Key Responsibilities:
  • Lead and manage complex drug discovery research projects from inception to candidate selection.
  • Design and execute innovative experimental strategies to identify and validate novel drug targets.
  • Develop and optimize high-throughput screening assays and other biological assays.
  • Interpret complex biological data, draw sound conclusions, and present findings to stakeholders.
  • Mentor and guide junior research scientists, fostering their scientific and professional development.
  • Collaborate with internal and external partners to advance discovery programs.
  • Contribute to the strategic planning of the drug discovery pipeline.
  • Ensure compliance with safety protocols and maintain meticulous laboratory records.
  • Stay current with scientific literature and emerging technologies in relevant therapeutic areas.
Qualifications:
  • PhD in Molecular Biology, Biochemistry, Pharmacology, or a related life science discipline.
  • Minimum of 7 years of post-doctoral and industry experience in drug discovery.
  • Demonstrated success in leading research projects and delivering results.
  • Expertise in target identification and validation, assay development, and lead optimization.
  • Proficiency in data analysis and interpretation using relevant software.
  • Excellent communication, presentation, and leadership skills.
  • Experience with various therapeutic areas and their associated biological pathways.
  • Familiarity with state-of-the-art drug discovery technologies.
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Senior Medicinal Chemist - Drug Discovery

CB2 0AW Cambridge, Eastern £60000 Annually WhatJobs

Posted 1 day ago

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full-time
Our client, a leading pharmaceutical research organization, is seeking a highly motivated and experienced Senior Medicinal Chemist to join their cutting-edge drug discovery team in Cambridge, Cambridgeshire, UK . This pivotal role involves the design, synthesis, and optimization of novel small molecule drug candidates for unmet medical needs. You will be instrumental in driving projects from early-stage hit identification through to lead optimization, working collaboratively with biologists, pharmacologists, and DMPK scientists.

Key Responsibilities:
  • Design and synthesize novel chemical entities with desired pharmacological properties.
  • Develop and troubleshoot synthetic routes for target molecules, often involving multi-step syntheses.
  • Characterize synthesized compounds using a range of analytical techniques (NMR, MS, HPLC).
  • Optimize lead compounds to improve potency, selectivity, and pharmacokinetic profiles.
  • Stay abreast of the latest scientific literature and technological advancements in medicinal chemistry and drug discovery.
  • Present research findings at internal meetings and potentially at external scientific conferences.
  • Contribute to the intellectual property portfolio through invention disclosures and patent filings.
  • Mentor junior chemists and provide technical guidance.
  • Collaborate effectively within multidisciplinary project teams.
  • Manage external collaborations with CROs as needed.
Qualifications:
  • Ph.D. in Organic Chemistry, Medicinal Chemistry, or a closely related field.
  • A minimum of 5 years of post-doctoral or industrial experience in medicinal chemistry, with a proven track record of contributing to drug discovery programs.
  • Strong expertise in synthetic organic chemistry, including asymmetric synthesis and modern catalytic methods.
  • Proficiency in structure-activity relationship (SAR) analysis and iterative design.
  • Familiarity with drug discovery processes and relevant biological assays.
  • Excellent problem-solving skills and a creative approach to chemical challenges.
  • Strong written and verbal communication skills.
  • Ability to work independently and as part of a team in a fast-paced research environment.
  • Experience with computational chemistry tools is a plus.
This is an exceptional opportunity to make a significant impact in the pharmaceutical industry and contribute to the development of life-changing medicines. The successful candidate will benefit from a competitive salary, comprehensive benefits package, and opportunities for professional growth within a dynamic research setting. If you are a passionate and skilled medicinal chemist looking for your next challenge, we encourage you to apply. Located in the vibrant scientific hub of Cambridge, Cambridgeshire, UK , this role offers a stimulating work environment and excellent career prospects.
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Lead Research Scientist - Drug Discovery

CB2 0SW Cambridge, Eastern £70000 Annually WhatJobs

Posted 1 day ago

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full-time
Our client, a pioneering biopharmaceutical company at the forefront of developing innovative therapies for unmet medical needs, is seeking a highly accomplished Lead Research Scientist - Drug Discovery to join their world-class, fully remote R&D team. This is an exceptional opportunity for an experienced scientist to drive critical early-stage drug discovery projects from conception through to candidate selection. You will be responsible for designing and executing complex research strategies, leading a multidisciplinary team of scientists, and contributing significantly to the company's pipeline. Your expertise will be crucial in identifying novel therapeutic targets, developing and validating cutting-edge assays, and implementing innovative approaches in small molecule or biologic drug discovery. You will play a key role in analysing experimental data, interpreting results, and making critical decisions regarding project progression. Collaboration with internal departments, including preclinical development, chemistry, and translational medicine, as well as external academic and industry partners, will be essential. The ideal candidate will possess a PhD in a relevant life science discipline (e.g., molecular biology, pharmacology, biochemistry), a strong publication record, and a minimum of 5-7 years of experience in drug discovery within the pharmaceutical or biotechnology industry. Proven leadership capabilities, excellent problem-solving skills, and a deep understanding of modern drug discovery methodologies are required. The ability to thrive in a fast-paced, innovative, and remote research environment, coupled with strong communication and interpersonal skills, is paramount. This role offers the chance to make a profound impact on patient lives by contributing to the development of groundbreaking medicines.

Responsibilities:
  • Design and execute cutting-edge research strategies for drug discovery programs.
  • Lead and mentor a team of research scientists, fostering a collaborative environment.
  • Identify and validate novel therapeutic targets.
  • Develop and optimise biochemical and cellular assays.
  • Drive the discovery of small molecule or biologic drug candidates.
  • Analyse, interpret, and report complex experimental data.
  • Collaborate with internal and external stakeholders to advance projects.
  • Contribute to project planning and strategic decision-making.
  • Stay abreast of the latest advancements in drug discovery and relevant therapeutic areas.
  • Author scientific publications and present findings at conferences.
Qualifications:
  • PhD in Molecular Biology, Pharmacology, Biochemistry, or a related field.
  • 5+ years of experience in drug discovery within the pharmaceutical or biotech industry.
  • Proven track record of leading research projects and teams.
  • Extensive experience in assay development and optimisation.
  • Strong understanding of small molecule or biologic drug discovery processes.
  • Excellent analytical, problem-solving, and critical thinking skills.
  • Strong publication record and presentation experience.
  • Proficiency with relevant scientific software and databases.
  • Exceptional communication and interpersonal skills.
  • Ability to work effectively in a remote research setting.
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Senior Research Scientist - Drug Discovery

CB21 6GP Cambridge, Eastern £70000 Annually WhatJobs

Posted 1 day ago

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full-time
Our client, a leading innovator in pharmaceutical research, is seeking a highly motivated and experienced Senior Research Scientist to join their cutting-edge drug discovery team. This role is entirely remote, allowing you to contribute from anywhere in the UK.

Responsibilities:
  • Design and execute complex in vitro and in vivo experiments to identify and validate novel therapeutic targets.
  • Develop and optimize assay methodologies for high-throughput screening and lead optimization.
  • Analyze and interpret experimental data, drawing insightful conclusions and making recommendations for future research directions.
  • Collaborate closely with cross-functional teams, including medicinal chemists, biologists, and pharmacologists, to advance drug candidates through the pipeline.
  • Prepare detailed reports, presentations, and manuscripts for internal and external dissemination.
  • Mentor junior scientists and contribute to a culture of scientific excellence and innovation.
  • Stay abreast of the latest scientific literature and technological advancements in relevant therapeutic areas.
  • Manage project timelines and resources effectively in a remote work environment.
  • Contribute to the intellectual property portfolio through patent filings and publications.
Qualifications:
  • Ph.D. in Molecular Biology, Pharmacology, Biochemistry, or a related life science discipline.
  • A minimum of 5 years of post-doctoral or industry experience in drug discovery, with a strong track record of success.
  • Proven expertise in assay development, screening, and hit-to-lead optimization.
  • In-depth knowledge of specific therapeutic areas (e.g., oncology, immunology, neurology) is highly desirable.
  • Exceptional analytical and problem-solving skills, with a rigorous approach to experimental design and data interpretation.
  • Excellent communication and interpersonal skills, with the ability to effectively collaborate in a virtual team setting.
  • Proficiency in relevant scientific software and data analysis tools.
  • Demonstrated ability to work independently and manage multiple projects simultaneously.
  • Experience with regulatory requirements and documentation for drug development is a plus.
This is an exceptional opportunity to make a significant impact on the development of life-changing medicines within a dynamic and supportive remote working culture. You will be based remotely, contributing to our client's groundbreaking work in Cambridge, Cambridgeshire, UK .
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Principal Pharmaceutical Scientist - Drug Discovery

CB2 1AA Cambridge, Eastern £80000 Annually WhatJobs

Posted 1 day ago

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full-time
Our client, a cutting-edge pharmaceutical company at the forefront of medical innovation, is seeking an exceptional Principal Pharmaceutical Scientist to join their world-class, fully remote drug discovery team. This is a senior role offering the opportunity to lead groundbreaking research and development efforts in novel therapeutics. You will be responsible for designing and executing complex research projects, contributing to the identification and validation of new drug targets, and developing innovative drug delivery systems.

This remote-first position requires a highly experienced scientist with a PhD and a proven track record in pharmaceutical research, medicinal chemistry, or a related field. You will leverage your deep scientific expertise and leadership skills to drive research initiatives, collaborate with cross-functional teams, and contribute to the company's pipeline advancement.
Key Responsibilities:
  • Lead and manage complex research projects in drug discovery and development.
  • Design, synthesize, and characterize novel small molecules or biologics.
  • Identify and validate potential drug targets and therapeutic approaches.
  • Develop and optimize drug delivery strategies for various routes of administration.
  • Conduct in vitro and in vivo studies to assess drug efficacy and safety.
  • Analyze experimental data, interpret results, and draw insightful conclusions.
  • Author scientific reports, publications, and patent applications.
  • Collaborate with internal teams (e.g., biology, DMPK, toxicology) and external partners.
  • Mentor and guide junior scientists and research associates.
  • Stay abreast of the latest scientific advancements and technological innovations in the pharmaceutical industry.

Qualifications:
  • PhD in Pharmaceutical Sciences, Medicinal Chemistry, Organic Chemistry, or a closely related field.
  • 10+ years of post-doctoral or industry experience in drug discovery and development.
  • Demonstrated expertise in at least one core area of pharmaceutical R&D (e.g., medicinal chemistry, formulation development, pharmacokinetics).
  • Proven ability to design and execute complex research strategies.
  • Strong track record of scientific publications and/or patent filings.
  • Excellent analytical, problem-solving, and critical thinking skills.
  • Exceptional communication, presentation, and interpersonal skills, crucial for remote collaboration.
  • Experience with project leadership and team mentoring.

This is a remarkable opportunity to shape the future of medicine from a remote location, contributing to significant advancements in patient care globally, impacting research and development relevant to **Cambridge, Cambridgeshire, UK**, and beyond. Join a visionary team dedicated to scientific excellence.
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Principal Computational Chemist - Drug Discovery

CB2 1TN Cambridge, Eastern £75000 Annually WhatJobs

Posted 3 days ago

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full-time
Our client, a cutting-edge biopharmaceutical company at the forefront of innovative drug discovery, is seeking a Principal Computational Chemist to drive their molecular modeling and cheminformatics efforts. This is a fully remote position, allowing you to contribute your expertise to groundbreaking research from anywhere within the UK. You will play a pivotal role in the design and optimization of novel therapeutic candidates through the application of advanced computational techniques. Responsibilities include leading the development and implementation of computational chemistry strategies, including molecular docking, molecular dynamics simulations, QSAR modeling, and virtual screening. You will collaborate closely with medicinal chemists, biologists, and pharmacologists to interpret experimental data, propose new chemical entities, and guide structure-activity relationship studies. Developing and maintaining robust cheminformatics pipelines, databases, and analysis tools is a key function. This role requires staying abreast of the latest advancements in computational chemistry, artificial intelligence, and machine learning as applied to drug discovery. You will be responsible for mentoring junior computational chemists and contributing to the strategic direction of the computational chemistry group. Expertise in programming languages commonly used in scientific computing (e.g., Python, R) and experience with relevant software packages (e.g., Schrödinger Suite, MOE, GROMACS) are essential. A deep understanding of organic chemistry principles and drug discovery processes is crucial. The ideal candidate will possess a PhD in Computational Chemistry, Cheminformatics, or a closely related field, with a significant track record of impactful contributions to drug discovery projects. Excellent communication and collaboration skills are vital for effective interdisciplinary teamwork. You must be a proactive, independent researcher capable of managing complex projects in a remote setting. Join our dynamic team and help accelerate the discovery of life-saving medicines. The job location is **Cambridge, Cambridgeshire, UK**, though the role is conducted remotely.
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Scientific Sales Manager - Drug Discovery Tools

CB1 Cherry Hinton, Eastern Newton Colmore

Posted 4 days ago

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full time

Scientific Sales Manager - Drug Discovery Tools

Newton Colmore is working with an exciting biotech company in Cambridge who are looking to hire a Sales Manager to lead the commercialisation of their latest drug discovery tool.

As a Sales Manager in this growing company, you will be utilising your molecular biology or biochemistry expertise and sales acumen to identify and win new customers. This is a pivotal role for the company, and you will be responsible for building a new sales strategy, attending industry events, building new relationships and engaging with key stakeholders.

The company have developed a new desktop tool that aims to speed up and improve drug discovery outcomes with novel technology that is at the intersection of science and engineering.

You will be utilising your scientific commercial experience to interact directly with potential customers and to help them understand more about the technology and how it can improve their discovery capabilities.

To be considered for this exciting role you will need to have the following;

  • Prior sales experience, ideally within a drug discovery setting.
  • Biology or Biochemistry academics.
  • Some knowledge of bioprocessing or protein assays would be ideal.
  • Be a great communicator and enjoy travelling with work (around 30%).

The company are offering competitive salaries coupled with a strong benefits package as well as excellent growth opportunities in a fast-growing company. They will provide you with all the tools you need to make this role a success. Share options are also available.

The company have created a hierarchy-free environment that fosters innovation and progress, meaning you can make a real difference with your ideas.

This is an opportunity not to be missed so make an application now. For more details speak with Matthew Lowdon, medical devices recruitment specialist at Newton Colmore Consulting on (phone number removed).

Newton Colmore Consulting is a specialist recruitment consultancy operating within the medical devices and scientific engineering sectors. We conduct bespoke searches for our clients across the globe. We are continually running searches across R&D so take a look at our open roles on our website.

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Scientific Sales Manager - Drug Discovery Tools

Cambridgeshire, Eastern £45000 - £55000 Annually Newton Colmore

Posted 4 days ago

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permanent

Scientific Sales Manager - Drug Discovery Tools

Newton Colmore is working with an exciting biotech company in Cambridge who are looking to hire a Sales Manager to lead the commercialisation of their latest drug discovery tool.

As a Sales Manager in this growing company, you will be utilising your molecular biology or biochemistry expertise and sales acumen to identify and win new customers. This is a pivotal role for the company, and you will be responsible for building a new sales strategy, attending industry events, building new relationships and engaging with key stakeholders.

The company have developed a new desktop tool that aims to speed up and improve drug discovery outcomes with novel technology that is at the intersection of science and engineering.

You will be utilising your scientific commercial experience to interact directly with potential customers and to help them understand more about the technology and how it can improve their discovery capabilities.

To be considered for this exciting role you will need to have the following;

  • Prior sales experience, ideally within a drug discovery setting.
  • Biology or Biochemistry academics.
  • Some knowledge of bioprocessing or protein assays would be ideal.
  • Be a great communicator and enjoy travelling with work (around 30%).

The company are offering competitive salaries coupled with a strong benefits package as well as excellent growth opportunities in a fast-growing company. They will provide you with all the tools you need to make this role a success. Share options are also available.

The company have created a hierarchy-free environment that fosters innovation and progress, meaning you can make a real difference with your ideas.

This is an opportunity not to be missed so make an application now. For more details speak with Matthew Lowdon, medical devices recruitment specialist at Newton Colmore Consulting on (phone number removed).

Newton Colmore Consulting is a specialist recruitment consultancy operating within the medical devices and scientific engineering sectors. We conduct bespoke searches for our clients across the globe. We are continually running searches across R&D so take a look at our open roles on our website.

This advertiser has chosen not to accept applicants from your region.
 

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