30 Astrazeneca jobs in London
Principal Scientist, Drug Discovery
SW1A 0AA London, London
£75000 Annually
WhatJobs
Posted 3 days ago
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Job Description
Our client, a leading innovator in the pharmaceutical sector, is seeking a highly experienced Principal Scientist to join their prestigious Research & Development team. This hybrid role, based in London, England, UK , offers the opportunity to contribute to groundbreaking drug discovery initiatives. The Principal Scientist will lead ambitious research projects, driving the identification and validation of novel therapeutic targets and small molecule leads.
Key responsibilities include designing and executing complex experiments, developing innovative assays, and interpreting scientific data to guide project strategy. You will mentor and supervise junior scientists, foster a collaborative research environment, and contribute to scientific publications and patent applications. The Principal Scientist will also play a key role in evaluating new technologies and methodologies to enhance drug discovery capabilities. A strong understanding of medicinal chemistry, pharmacology, and disease biology relevant to the client's therapeutic areas is essential. Experience with high-throughput screening (HTS) and compound library management is highly desirable.
The ideal candidate will possess a PhD in a relevant scientific discipline (e.g., Pharmacology, Biochemistry, Molecular Biology) with a minimum of 7 years of post-doctoral research experience in the pharmaceutical or biotechnology industry. Demonstrated leadership in project management and a strong publication record are required. Excellent communication, presentation, and critical thinking skills are paramount. This is an exceptional opportunity for a talented scientist to make a significant impact on the future of medicine within a world-class research organisation.
Key responsibilities include designing and executing complex experiments, developing innovative assays, and interpreting scientific data to guide project strategy. You will mentor and supervise junior scientists, foster a collaborative research environment, and contribute to scientific publications and patent applications. The Principal Scientist will also play a key role in evaluating new technologies and methodologies to enhance drug discovery capabilities. A strong understanding of medicinal chemistry, pharmacology, and disease biology relevant to the client's therapeutic areas is essential. Experience with high-throughput screening (HTS) and compound library management is highly desirable.
The ideal candidate will possess a PhD in a relevant scientific discipline (e.g., Pharmacology, Biochemistry, Molecular Biology) with a minimum of 7 years of post-doctoral research experience in the pharmaceutical or biotechnology industry. Demonstrated leadership in project management and a strong publication record are required. Excellent communication, presentation, and critical thinking skills are paramount. This is an exceptional opportunity for a talented scientist to make a significant impact on the future of medicine within a world-class research organisation.
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0
Principal Scientist, Drug Discovery
SW1A 0AA London, London
£85000 Annually
WhatJobs
Posted 10 days ago
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Job Description
Our client is a world-leading biotechnology company at the forefront of pharmaceutical innovation. They are seeking an exceptional Principal Scientist to drive critical research initiatives within their drug discovery division. This is a fully remote position, offering a unique opportunity to shape the future of medicine from your home laboratory or office. You will be responsible for leading complex research projects, developing novel therapeutic strategies, and contributing to the advancement of our preclinical and clinical pipelines. Key responsibilities include designing and executing sophisticated experiments, analysing complex biological data, and interpreting results to guide project direction. You will be expected to identify and validate new drug targets, develop innovative assay methodologies, and contribute to the preclinical characterisation of drug candidates. Collaboration with internal multidisciplinary teams, including medicinal chemists, pharmacologists, and clinical researchers, as well as external academic partners, will be essential. The ideal candidate will possess a deep understanding of molecular biology, pharmacology, or a related field, with a strong publication record and extensive experience in drug discovery. Proven experience in leading research projects, mentoring junior scientists, and contributing to strategic R&D decisions is highly desirable. You should be adept at critical thinking, possess excellent problem-solving skills, and be passionate about scientific advancement. As a remote role, outstanding communication, presentation, and self-management skills are crucial for effective collaboration and leadership. This role offers a challenging and rewarding opportunity to make a significant impact on patient lives through cutting-edge scientific research.
Key Responsibilities:
Qualifications:
Key Responsibilities:
- Lead and design complex research projects in drug discovery.
- Develop and implement novel scientific methodologies and assays.
- Identify and validate potential drug targets and therapeutic strategies.
- Conduct in-depth analysis of biological and pharmacological data.
- Interpret experimental results and guide project progression.
- Collaborate with internal and external research teams and stakeholders.
- Mentor and supervise junior scientific staff.
- Contribute to the strategic direction of the R&D pipeline.
- Author scientific publications and present research findings.
- Ensure compliance with safety and ethical research standards.
Qualifications:
- PhD in Molecular Biology, Pharmacology, Biochemistry, or a related life science discipline.
- Minimum of 8 years of post-doctoral research experience in drug discovery or a related field.
- Proven track record of leading successful research projects and publications in high-impact journals.
- Extensive experience in experimental design, execution, and data analysis.
- Expertise in relevant therapeutic areas and/or scientific disciplines (e.g., oncology, immunology, neuroscience).
- Demonstrated leadership, mentoring, and project management skills.
- Excellent analytical, critical thinking, and problem-solving abilities.
- Outstanding written and verbal communication and presentation skills.
- Experience working independently and collaboratively in a remote research setting.
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1
Principal Scientist - Drug Discovery
SW1A 0 London, London
£80000 Annually
WhatJobs
Posted 15 days ago
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Job Description
Our client is seeking a highly accomplished Principal Scientist to lead groundbreaking research and development initiatives within their cutting-edge drug discovery division, located in London, England, UK . This senior scientific role demands exceptional expertise in molecular biology, pharmacology, or a related life science discipline, with a proven track record of successfully advancing therapeutic candidates from early discovery through to pre-clinical development. You will be responsible for designing and executing complex experimental strategies, interpreting data, and mentoring a team of talented scientists. This is a critical role contributing to the development of novel treatments for unmet medical needs. Key responsibilities include:
A PhD in Molecular Biology, Pharmacology, Biochemistry, or a closely related field is mandatory, coupled with substantial post-doctoral and industry experience in drug discovery. Demonstrated expertise in a specific therapeutic area (e.g., oncology, immunology, neuroscience) is highly desirable. Excellent leadership, communication, and critical thinking skills are essential. The successful candidate will have a passion for scientific innovation and a commitment to driving meaningful advancements in medicine, working within a world-class research facility in the heart of London .
- Leading and directing research programs focused on identifying and validating novel drug targets and developing therapeutic agents.
- Designing, implementing, and optimizing complex experimental assays and workflows.
- Interpreting experimental data, drawing robust conclusions, and communicating findings to internal and external stakeholders.
- Developing and managing project timelines, resources, and budgets.
- Mentoring and guiding junior scientists, fostering a collaborative and innovative research environment.
- Writing scientific publications, patent applications, and regulatory submissions.
- Collaborating closely with other scientific disciplines, including medicinal chemistry, DMPK, and translational science.
- Evaluating new technologies and methodologies to enhance discovery capabilities.
- Ensuring compliance with all safety, ethical, and regulatory guidelines.
A PhD in Molecular Biology, Pharmacology, Biochemistry, or a closely related field is mandatory, coupled with substantial post-doctoral and industry experience in drug discovery. Demonstrated expertise in a specific therapeutic area (e.g., oncology, immunology, neuroscience) is highly desirable. Excellent leadership, communication, and critical thinking skills are essential. The successful candidate will have a passion for scientific innovation and a commitment to driving meaningful advancements in medicine, working within a world-class research facility in the heart of London .
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2
Principal Scientist, Drug Discovery
W1A 0AX London, London
£75000 Annually
WhatJobs
Posted 16 days ago
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Job Description
Our client, a pioneering biopharmaceutical company, is seeking a highly accomplished Principal Scientist to join their world-class Scientific Research & Development team in London, England, UK . This pivotal role will focus on driving cutting-edge research in drug discovery and development. You will lead projects aimed at identifying and validating novel therapeutic targets, designing and synthesizing small molecules or biologics, and advancing potential drug candidates through preclinical stages. This position requires extensive expertise in molecular biology, pharmacology, or a related discipline, along with a strong publication record.
Key responsibilities include designing and executing complex research experiments, interpreting data, and contributing to the strategic direction of discovery programs. You will collaborate with cross-functional teams, including medicinal chemists, computational biologists, and toxicologists, to overcome scientific challenges and accelerate the drug development pipeline. The Principal Scientist will also be responsible for mentoring junior researchers, staying abreast of the latest scientific literature, and presenting findings at internal and external conferences. A deep understanding of disease mechanisms and the ability to translate scientific insights into actionable research plans are essential.
The ideal candidate will hold a PhD in a relevant scientific discipline (e.g., Molecular Biology, Biochemistry, Pharmacology, Chemistry) and possess a minimum of 7 years of post-doctoral research experience in the pharmaceutical or biotechnology industry. A proven track record of success in drug discovery, evidenced by peer-reviewed publications and successful progression of projects, is required. Strong analytical and problem-solving skills, coupled with excellent written and verbal communication abilities, are crucial. Experience in leading research teams and managing complex scientific projects is highly valued. This is an exceptional opportunity to make a significant impact on the future of medicine and contribute to life-saving therapies.
Qualifications:
Key responsibilities include designing and executing complex research experiments, interpreting data, and contributing to the strategic direction of discovery programs. You will collaborate with cross-functional teams, including medicinal chemists, computational biologists, and toxicologists, to overcome scientific challenges and accelerate the drug development pipeline. The Principal Scientist will also be responsible for mentoring junior researchers, staying abreast of the latest scientific literature, and presenting findings at internal and external conferences. A deep understanding of disease mechanisms and the ability to translate scientific insights into actionable research plans are essential.
The ideal candidate will hold a PhD in a relevant scientific discipline (e.g., Molecular Biology, Biochemistry, Pharmacology, Chemistry) and possess a minimum of 7 years of post-doctoral research experience in the pharmaceutical or biotechnology industry. A proven track record of success in drug discovery, evidenced by peer-reviewed publications and successful progression of projects, is required. Strong analytical and problem-solving skills, coupled with excellent written and verbal communication abilities, are crucial. Experience in leading research teams and managing complex scientific projects is highly valued. This is an exceptional opportunity to make a significant impact on the future of medicine and contribute to life-saving therapies.
Qualifications:
- PhD in Molecular Biology, Biochemistry, Pharmacology, Chemistry, or a related field.
- Minimum of 7 years of post-doctoral research experience in the pharmaceutical/biotech industry.
- Proven track record in drug discovery and development.
- Extensive experience in experimental design, execution, and data analysis.
- Strong publication record in peer-reviewed journals.
- Expertise in relevant therapeutic areas or research methodologies.
- Excellent communication, leadership, and collaboration skills.
- Ability to mentor and guide junior scientists.
- Experience in project leadership and strategic planning.
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3
Lead Research Scientist - Drug Discovery
SW1A 0AA London, London
£75000 Annually
WhatJobs
Posted 5 days ago
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Job Description
Our client, a groundbreaking pharmaceutical company at the forefront of medical innovation, is seeking an accomplished Lead Research Scientist to join their dedicated drug discovery team. This role is critical in driving the identification and validation of novel therapeutic targets and the development of innovative drug candidates. You will be responsible for designing and executing complex research projects, leading a team of talented scientists, and contributing to the strategic direction of the R&D pipeline. The ideal candidate will possess a PhD in a relevant scientific discipline (e.g., Pharmacology, Molecular Biology, Biochemistry), a strong track record of publications and patents, and extensive experience in preclinical drug discovery. Expertise in specific therapeutic areas, assay development, compound screening, and in vivo/in vitro pharmacology is highly desirable. You will foster a collaborative research environment, mentor junior scientists, and effectively communicate research findings to both scientific and non-scientific stakeholders. This position offers the opportunity to make a significant impact on patient lives by advancing novel therapies from concept to clinical trials, working within a state-of-the-art facility located in London, England, UK .
Key Responsibilities:
Key Responsibilities:
- Lead and manage research projects focused on novel drug discovery.
- Design and implement experimental strategies for target identification and validation.
- Oversee the development and optimisation of biological assays.
- Direct compound screening campaigns and lead optimisation efforts.
- Interpret experimental data and draw conclusions to guide research direction.
- Mentor and supervise a team of research scientists and technicians.
- Prepare scientific reports, presentations, and publications.
- Collaborate with cross-functional teams including chemistry, DMPK, and toxicology.
- Contribute to the strategic planning of the R&D pipeline.
- Ensure compliance with all laboratory safety and ethical guidelines.
- PhD in Pharmacology, Molecular Biology, Biochemistry, or a related life science field.
- Minimum of 8 years of post-doctoral research experience in drug discovery within the pharmaceutical or biotech industry.
- Proven expertise in a specific therapeutic area (e.g., oncology, immunology, CNS).
- Extensive experience in assay development, high-throughput screening (HTS), and in vitro/in vivo pharmacology.
- Strong understanding of modern drug discovery methodologies.
- Excellent scientific leadership, project management, and communication skills.
- Track record of peer-reviewed publications and/or patent filings.
- Ability to work effectively in a fast-paced, collaborative research environment.
- Experience with data analysis software and laboratory information management systems (LIMS).
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4
Principal Pharmaceutical Scientist - Drug Discovery
WC2N 5DU London, London
£85000 Annually
WhatJobs
Posted 8 days ago
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Job Description
Our client, a leading pharmaceutical company, is seeking a distinguished Principal Pharmaceutical Scientist to drive cutting-edge research and development in drug discovery. This is a fully remote position, allowing you to contribute your expertise from anywhere in the UK. You will play a crucial role in identifying, validating, and advancing novel therapeutic candidates through the early stages of the drug development pipeline. This senior role demands a profound scientific background, extensive experience in pharmaceutical research, and a passion for innovation in medicinal chemistry, pharmacology, or a related discipline. Key responsibilities include designing and executing complex research projects to discover new drug targets and molecules; leading multidisciplinary teams in the development of innovative therapeutic strategies; critically evaluating scientific data, literature, and experimental results; authoring high-impact scientific publications and patent applications; presenting research findings at internal and external scientific forums; mentoring and guiding junior scientists; collaborating with external academic institutions and industry partners; ensuring compliance with all relevant regulatory guidelines and ethical standards; and contributing to the strategic direction of the R&D department. The ideal candidate will possess a Ph.D. in Pharmaceutical Sciences, Chemistry, Biology, or a closely related field, with a minimum of 8-10 years of progressive experience in drug discovery research within the pharmaceutical or biotechnology industry. A strong publication record and proven track record of successfully advancing drug candidates from discovery to preclinical development are essential. Expertise in specific therapeutic areas (e.g., oncology, immunology, neuroscience) is highly desirable. Exceptional leadership, communication, and interpersonal skills are required to effectively lead research teams and collaborate with diverse stakeholders in a remote setting. A deep understanding of modern drug discovery technologies, including high-throughput screening, structural biology, and computational chemistry, is also critical. This is a unique opportunity to make a significant contribution to the development of life-changing medicines while benefiting from a flexible, remote work environment. You will be at the forefront of scientific innovation, working on challenging projects that have the potential to impact global health. The successful candidate will be a strategic thinker, a results-oriented scientist, and a collaborative team player who thrives in a challenging and dynamic research landscape. The company is committed to fostering a culture of scientific excellence, innovation, and continuous learning.
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5
Senior Research Scientist - Drug Discovery
SW1A 0AA London, London
£70000 Annually
WhatJobs
Posted 8 days ago
Job Viewed
Job Description
Our client, a world-leading biopharmaceutical research organisation, is seeking a highly accomplished Senior Research Scientist specialising in Drug Discovery to join their fully remote scientific team. This pivotal role involves leading cutting-edge research projects aimed at identifying and validating novel therapeutic targets and developing innovative drug candidates. The ideal candidate will possess a strong scientific background, extensive experience in preclinical drug discovery, and a proven ability to design and execute complex experiments, analyse data, and publish findings. As this is a fully remote position, exceptional communication, data management, and collaboration skills utilising advanced scientific software and digital platforms are essential. You will contribute to the advancement of new medicines, working within a dynamic and intellectually stimulating research environment.
Key Responsibilities:
Qualifications:
This is a fully remote position, offering unparalleled flexibility and the opportunity to contribute to groundbreaking research from anywhere in the UK. Our client is dedicated to advancing human health through pioneering scientific discovery.
Key Responsibilities:
- Design, execute, and interpret complex in vitro and in vivo experiments to identify and characterise potential drug candidates.
- Develop and optimise assays for target validation, compound screening, and lead optimisation.
- Analyse large datasets using statistical and bioinformatics tools, drawing meaningful conclusions and making data-driven recommendations.
- Stay abreast of the latest scientific literature and technological advancements in relevant therapeutic areas and drug discovery methodologies.
- Collaborate effectively with internal and external partners, including academic institutions and other research organisations.
- Contribute to the preparation of scientific manuscripts for publication in peer-reviewed journals and present findings at scientific conferences.
- Manage project timelines, resources, and budgets effectively.
- Mentor and guide junior scientists and research associates.
- Ensure all research activities are conducted in accordance with ethical guidelines and regulatory requirements.
- Contribute to intellectual property generation through patent applications.
- Utilise advanced computational tools and platforms for data analysis and interpretation in a remote setting.
Qualifications:
- PhD in Molecular Biology, Pharmacology, Biochemistry, Immunology, or a related life science discipline.
- Minimum of 5-7 years of post-doctoral research experience in drug discovery, preferably within a pharmaceutical or biotechnology setting.
- Proven track record of success in identifying and validating drug targets and advancing candidates through the early stages of discovery.
- Extensive hands-on experience with a range of molecular biology, biochemical, and cell-based assay techniques.
- Proficiency in data analysis software (e.g., GraphPad Prism, R) and bioinformatics tools.
- Strong understanding of medicinal chemistry principles and pharmacokinetics/pharmacodynamics (PK/PD).
- Excellent scientific writing and presentation skills.
- Ability to work independently, manage multiple projects, and collaborate effectively in a fully remote, highly collaborative scientific environment.
- A creative, problem-solving mindset with a passion for scientific innovation.
This is a fully remote position, offering unparalleled flexibility and the opportunity to contribute to groundbreaking research from anywhere in the UK. Our client is dedicated to advancing human health through pioneering scientific discovery.
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6
Senior Drug Discovery Scientist (Oncology)
SW1A 0AA London, London
£60000 Annually
WhatJobs
Posted 11 days ago
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Job Description
Our client, a pioneering biopharmaceutical company at the forefront of cancer research, is actively recruiting a Senior Drug Discovery Scientist specializing in Oncology to join their fully remote, world-class research team. This role is pivotal in advancing our pipeline of innovative cancer therapeutics, requiring a deep understanding of cancer biology, target validation, and early-stage drug discovery.
Responsibilities:
Responsibilities:
- Lead and execute research projects focused on identifying novel oncology targets and developing targeted therapies.
- Design and implement in vitro and ex vivo assays to evaluate drug candidates for efficacy and mechanism of action.
- Utilize cutting-edge technologies and methodologies in cancer biology, genomics, and proteomics.
- Collaborate with medicinal chemists and pharmacologists to optimize lead compounds.
- Analyze and interpret complex biological data, drawing meaningful conclusions and making strategic recommendations.
- Prepare high-quality scientific reports, manuscripts for publication, and presentations for internal and external forums.
- Stay abreast of the latest advancements in oncology research and drug discovery through literature review and conference attendance.
- Mentor and guide junior scientists, fostering a collaborative and innovative research environment.
- Contribute to the development of intellectual property, including patent filings.
- Ensure meticulous experimental design, data integrity, and adherence to laboratory best practices.
- PhD in Cancer Biology, Molecular Biology, Pharmacology, or a closely related field.
- A minimum of 5 years of post-doctoral or industry experience in oncology drug discovery.
- Proven expertise in cancer cell biology, tumor microenvironment, or immunotherapy.
- Hands-on experience with a variety of cellular assays, molecular biology techniques, and potentially in vivo models.
- Strong understanding of small molecule and/or biologics drug discovery processes.
- Demonstrated ability to design, execute, and interpret complex experiments.
- Excellent analytical and problem-solving skills.
- Exceptional written and oral communication skills, with a strong publication record in reputable journals.
- Ability to work independently and lead projects in a remote setting.
- A passion for advancing cancer treatment and a commitment to scientific rigor.
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7
Principal Medicinal Chemist - Drug Discovery
SW1A 0AA London, London
£75000 Annually
WhatJobs
Posted 14 days ago
Job Viewed
Job Description
Our client, a leading pharmaceutical research company based in London, England, UK , is seeking a highly accomplished Principal Medicinal Chemist to drive innovation in drug discovery. This critical, on-site role involves leading and executing cutting-edge medicinal chemistry programs aimed at identifying and optimizing novel therapeutic agents. The ideal candidate will possess a PhD in Organic Chemistry or Medicinal Chemistry, coupled with extensive hands-on experience in the design, synthesis, and characterization of small molecule drug candidates. You will be responsible for strategizing and guiding synthetic efforts, employing structure-activity relationship (SAR) analysis, and utilizing computational chemistry tools to accelerate lead optimization. This position demands exceptional scientific acumen, a deep understanding of drug discovery principles, and proven leadership skills. You will mentor junior chemists, contribute to project strategy, and collaborate effectively with biologists, pharmacologists, and other cross-functional teams. A strong publication record and experience in managing external collaborations are highly desirable. We are looking for an individual with a proven track record of delivering successful drug candidates into preclinical and clinical development, who is passionate about discovering life-changing medicines and eager to contribute to a world-class research environment. Your expertise in synthetic organic chemistry, heterocyclic chemistry, and a broad knowledge of therapeutic areas will be essential. This is an unparalleled opportunity to make a significant impact on the future of pharmaceutical innovation within a highly collaborative and dynamic research setting. The scope of this role includes setting scientific direction, managing research projects, and contributing to the intellectual property portfolio.
Responsibilities:
Responsibilities:
- Lead medicinal chemistry efforts for drug discovery programs.
- Design and synthesize novel small molecules with therapeutic potential.
- Conduct SAR studies and optimize lead compounds for potency, selectivity, and ADME properties.
- Utilize computational chemistry tools and databases for molecular design.
- Collaborate with biologists and pharmacologists to advance drug candidates.
- Mentor and supervise junior medicinal chemists.
- Develop and execute synthetic routes for complex molecules.
- Evaluate and implement new synthetic methodologies.
- Contribute to project strategy and intellectual property generation.
- Present research findings at internal meetings and external conferences.
- PhD in Organic Chemistry, Medicinal Chemistry, or a closely related field.
- Minimum of 8 years of post-doctoral experience in medicinal chemistry within the pharmaceutical industry or biotech.
- Demonstrated expertise in small molecule drug design and synthesis.
- Strong understanding of SAR, ADMET properties, and drug discovery processes.
- Proficiency in modern synthetic organic chemistry techniques.
- Experience with computational chemistry and molecular modelling tools.
- Excellent problem-solving and analytical skills.
- Proven leadership and team management abilities.
- Strong written and verbal communication skills.
- Eligibility to work in the UK.
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8
Senior Research Scientist - Drug Discovery
EC1A 4JQ London, London
£65000 Annually
WhatJobs
Posted 15 days ago
Job Viewed
Job Description
Our client, a pioneering pharmaceutical company at the forefront of medical innovation, is looking for a highly skilled Senior Research Scientist to join their drug discovery team. This challenging position is based at their state-of-the-art facilities in London, England, UK , offering a hybrid working arrangement that combines essential laboratory work with the flexibility of remote collaboration. You will play a crucial role in identifying, validating, and characterizing novel drug targets and developing innovative therapeutic strategies. Key responsibilities include designing and conducting complex experiments, analyzing biological data, contributing to research project strategy, writing scientific reports and publications, and collaborating with internal and external research partners. The ideal candidate will have a PhD in a relevant life science discipline (e.g., molecular biology, pharmacology, biochemistry) with a proven track record in drug discovery or a related area. Expertise in specific therapeutic areas, advanced analytical techniques, and a deep understanding of preclinical development are highly desirable. You must possess excellent critical thinking, problem-solving skills, and the ability to work independently and as part of a multidisciplinary team. Strong written and verbal communication skills are essential for disseminating research findings and contributing to collaborative projects. This is an exceptional opportunity to contribute to the development of life-saving medicines and advance your career within a dynamic and research-intensive environment. You will be expected to lead research initiatives, mentor junior scientists, and contribute to the intellectual property portfolio of the company.
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