257 Drug Development jobs in London

Senior Research Scientist - Drug Discovery

WC2N 5DU London, London £75000 Annually WhatJobs

Posted 3 days ago

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full-time
Our client, a groundbreaking biopharmaceutical company at the forefront of innovative therapeutics, is seeking a highly motivated and experienced Senior Research Scientist to join their expanding Drug Discovery team. This is a fully remote position, offering the flexibility to work from anywhere within the UK, fostering a seamless integration of work and life. You will play a crucial role in identifying and validating novel drug targets, designing and executing experiments, and contributing to the preclinical development of next-generation medicines. The ideal candidate will possess a PhD in a relevant scientific discipline, extensive hands-on experience in molecular biology, cell biology, or biochemistry, and a strong publication record. You will be a self-starter, capable of independently driving research projects, troubleshooting complex problems, and effectively communicating scientific findings to a multidisciplinary team.

Key Responsibilities:
  • Design and implement cutting-edge research projects focused on the identification and validation of novel therapeutic targets.
  • Develop and optimize in vitro and ex vivo assays to assess compound efficacy and mechanism of action.
  • Conduct rigorous data analysis, interpret experimental results, and generate comprehensive reports.
  • Stay abreast of the latest scientific literature, emerging technologies, and competitive landscape in relevant therapeutic areas.
  • Collaborate effectively with medicinal chemists, pharmacologists, and other research scientists to advance drug candidates through the discovery pipeline.
  • Contribute to the preparation of scientific publications, patents, and regulatory submissions.
  • Present research findings at internal meetings and external scientific conferences.
  • Troubleshoot experimental challenges and propose innovative solutions.
  • Maintain accurate and detailed laboratory notebooks and research records.
  • Contribute to the strategic direction of the drug discovery program.
Qualifications:
  • PhD in Molecular Biology, Cell Biology, Biochemistry, Pharmacology, or a related field.
  • Minimum of 5 years of post-doctoral or industry research experience in drug discovery.
  • Proven expertise in a range of biological techniques, including but not limited to cell culture, western blotting, ELISA, qPCR, and high-throughput screening.
  • Experience with target validation and assay development.
  • Strong understanding of disease biology and target engagement.
  • Excellent data analysis and interpretation skills.
  • Proficiency in scientific writing and presentation.
  • Demonstrated ability to work independently and as a productive member of a remote team.
  • Strong problem-solving abilities and a creative scientific approach.
  • Familiarity with bioinformatics tools is a plus.
This remote opportunity is ideal for a passionate scientist looking to make a significant impact in the pharmaceutical industry. Our client offers a competitive remuneration package, excellent benefits, and the chance to work on transformative medicines.
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Principal Research Scientist - Drug Discovery

SW1A 0AA London, London £75000 Annually WhatJobs

Posted 8 days ago

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full-time
A world-renowned pharmaceutical company is seeking a highly experienced and innovative Principal Research Scientist to join their cutting-edge drug discovery team based in London, England, UK . This hybrid role offers an exciting opportunity to contribute to the development of novel therapeutics in a collaborative and dynamic research environment.

As a Principal Research Scientist, you will lead research projects focused on identifying and validating new drug targets, designing and synthesising novel chemical entities, and advancing lead compounds through preclinical development. Your expertise will be critical in designing and executing complex experiments, interpreting data, and contributing to the strategic direction of drug discovery programmes.

Key Responsibilities:
  • Lead and manage independent research projects within drug discovery, from target identification to preclinical candidate selection.
  • Design, synthesise, and characterise novel small molecules with therapeutic potential.
  • Develop and implement robust experimental assays to evaluate compound efficacy, selectivity, and mechanism of action.
  • Conduct detailed data analysis, interpretation, and reporting, presenting findings at internal and external scientific forums.
  • Collaborate closely with medicinal chemists, biologists, pharmacologists, and toxicologists to advance drug candidates.
  • Provide scientific leadership and mentorship to junior researchers and technicians.
  • Stay abreast of the latest scientific literature, technological advancements, and industry trends in pharmaceutical research.
  • Contribute to the strategic planning and prioritisation of drug discovery programmes.
  • Maintain excellent laboratory practices and ensure compliance with all relevant regulations and safety protocols.

Essential Qualifications:
  • PhD in Medicinal Chemistry, Organic Chemistry, Pharmacology, or a related life sciences discipline.
  • Minimum of 8 years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
  • Proven track record of successfully advancing drug candidates from discovery to preclinical development.
  • Extensive experience in synthetic organic chemistry, medicinal chemistry, and assay development.
  • Deep understanding of drug discovery processes and a broad knowledge of therapeutic areas.
  • Excellent analytical, problem-solving, and critical thinking skills.
  • Strong publication record and presentation skills.
  • Demonstrated ability to lead research teams and collaborate effectively in a multidisciplinary environment.
  • Familiarity with hybrid work models and effective remote collaboration tools.

This is a prestigious opportunity for a seasoned scientist to make a significant impact on patient lives by contributing to the development of next-generation medicines. You will be part of a world-class research organisation, pushing the boundaries of scientific innovation.
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Principal Research Scientist, Drug Discovery

SW1A 0AA London, London £90000 Annually WhatJobs

Posted 9 days ago

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full-time
Our client, a leading pharmaceutical innovator, is seeking a highly accomplished Principal Research Scientist to spearhead critical drug discovery initiatives within their state-of-the-art, fully remote research division. This is a unique opportunity to drive cutting-edge scientific research and contribute to the development of novel therapeutics. The ideal candidate will possess a deep expertise in medicinal chemistry, molecular biology, or a related field, with a proven track record of successfully translating scientific concepts into preclinical drug candidates. You will lead a virtual team of scientists, mentor junior researchers, and collaborate extensively with cross-functional teams, including clinical development, regulatory affairs, and business development. Your responsibilities will encompass designing and executing complex experiments, interpreting data, and identifying novel therapeutic targets. A strong understanding of disease biology and the drug discovery process is essential, along with extensive experience in target validation, hit identification, and lead optimization. This role demands exceptional analytical and problem-solving skills, as well as the ability to think creatively and strategically to overcome scientific challenges. As a remote-first position, you will need to demonstrate excellent communication, leadership, and project management capabilities to effectively guide research efforts from a distance. The ability to foster a collaborative and innovative research environment, even remotely, is paramount. You will be expected to publish research findings in high-impact journals and present at international conferences. The successful candidate will have access to advanced computational tools and resources to facilitate their research. This role offers the chance to make a significant impact on patient lives by advancing innovative medicines through the drug discovery pipeline, all while enjoying the flexibility of a remote work arrangement. Join a company committed to scientific excellence and patient well-being, working from your home base near London, England, UK .
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Lead Research Scientist - Drug Discovery

SW1A 0AA London, London £75000 Annually WhatJobs

Posted 10 days ago

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full-time
Our client, a pioneering pharmaceutical company, is seeking a highly accomplished Lead Research Scientist to spearhead drug discovery initiatives. This hybrid role, based in the heart of London, England, UK , offers a unique opportunity to blend cutting-edge laboratory work with strategic research planning. You will lead a team of talented scientists, driving the identification and validation of novel therapeutic targets and the development of innovative drug candidates. A strong background in a relevant scientific discipline, exceptional leadership capabilities, and a passion for translating scientific breakthroughs into life-changing medicines are essential.

Key Responsibilities:
  • Lead and manage a team of research scientists involved in early-stage drug discovery projects.
  • Design, execute, and interpret complex experiments to identify and validate novel drug targets.
  • Develop and implement innovative research strategies and methodologies.
  • Oversee the design and synthesis of potential drug molecules, and their preclinical evaluation.
  • Collaborate with internal cross-functional teams (e.g., chemistry, biology, DMPK) and external partners to advance projects.
  • Analyze and interpret experimental data, present findings at scientific conferences, and contribute to publications.
  • Manage research budgets, resources, and timelines effectively.
  • Stay abreast of the latest scientific advancements and emerging technologies in pharmaceutical research.
  • Mentor and guide junior scientists, fostering a culture of scientific excellence and innovation.
  • Ensure all research activities are conducted in compliance with ethical standards and regulatory guidelines.
Qualifications:
  • Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline.
  • Significant postdoctoral and industry experience in drug discovery.
  • Proven track record of leading research projects from concept to preclinical development.
  • Extensive experience in a specific therapeutic area (e.g., oncology, immunology, neuroscience).
  • Expertise in relevant experimental techniques and assays.
  • Strong understanding of medicinal chemistry principles and drug development processes.
  • Excellent leadership, team management, and communication skills.
  • Demonstrated ability to think critically and solve complex scientific problems.
  • Experience with grant writing and publications in high-impact journals.
  • Proficiency in data analysis software and laboratory information management systems.
This is an unparalleled opportunity to make a significant contribution to the future of medicine. If you are a visionary scientist with a passion for innovation and a commitment to patient well-being, we invite you to apply.
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Senior Research Scientist - Drug Discovery

SW1A 0AA London, London £60000 Annually WhatJobs

Posted 11 days ago

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full-time
Our client, a leading pharmaceutical innovator, is seeking a highly skilled and motivated Senior Research Scientist to join their cutting-edge Drug Discovery team based in London, England, UK . This pivotal role will involve spearheading research initiatives to identify and validate novel therapeutic targets and develop innovative drug candidates. You will be responsible for designing and executing complex experiments, analysing biological data, and contributing to the strategic direction of research programs. The ideal candidate will possess a strong background in molecular biology, cell biology, biochemistry, or a related life science discipline, with a proven track record of successful research contributions in a pharmaceutical or biotechnology setting. You will be expected to leverage your expertise in drug discovery methodologies, including target identification, lead optimisation, and preclinical development. Collaboration is key; you will work closely with a multidisciplinary team of scientists, clinicians, and project managers, contributing your insights and driving research forward. Excellent data interpretation and presentation skills are essential, as you will be responsible for documenting findings, preparing reports, and presenting results at internal meetings and external conferences. Staying abreast of the latest scientific literature and emerging technologies in drug discovery is crucial. This role offers the opportunity to work on challenging projects with significant patient impact and to contribute to the development of life-saving medicines. Experience with specific therapeutic areas such as oncology, immunology, or neurology is highly desirable. The ability to mentor junior scientists and foster a collaborative research environment is also valued. This is an exceptional opportunity for a driven scientist to make a significant impact in the pharmaceutical industry.

Responsibilities:
  • Lead and conduct advanced research projects in drug discovery.
  • Design, optimise, and perform complex biological assays.
  • Analyse and interpret complex datasets from various experimental platforms.
  • Identify and validate novel therapeutic targets.
  • Contribute to the optimisation of lead compounds.
  • Collaborate effectively with cross-functional research teams.
  • Prepare detailed research reports and present findings to stakeholders.
  • Stay current with scientific advancements and relevant literature.
  • Mentor and guide junior research staff.
  • Contribute to the strategic planning of research programs.
  • Ensure compliance with ethical and regulatory guidelines.
Qualifications:
  • PhD in Molecular Biology, Cell Biology, Biochemistry, Pharmacology, or a related field.
  • Minimum of 5-7 years of post-doctoral or industry experience in drug discovery.
  • Demonstrated expertise in experimental design and execution.
  • Strong publication record in peer-reviewed journals.
  • Proficiency in relevant biological techniques and instrumentation.
  • Experience with computational biology tools and bioinformatics analysis is a plus.
  • Excellent problem-solving and critical thinking skills.
  • Strong communication and presentation abilities.
  • Ability to work independently and manage multiple projects.
  • Experience in specific therapeutic areas (e.g., oncology, immunology) is preferred.
  • Leadership potential and team-player attitude.
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Senior Research Scientist - Drug Discovery

WC2A 2AA London, London £75000 Annually WhatJobs

Posted 16 days ago

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full-time
Our client, a leading pharmaceutical innovator, is seeking an accomplished Senior Research Scientist to drive groundbreaking advancements in drug discovery. This pivotal role within our R&D department will focus on identifying, validating, and optimising novel therapeutic targets and chemical entities. You will play a key role in designing and executing complex experiments, leading the interpretation of results, and contributing significantly to the preclinical development pipeline. The ideal candidate will possess extensive experience in molecular biology, biochemistry, and assay development, with a strong track record of successfully translating scientific insights into potential drug candidates. You will be adept at managing multiple research projects concurrently, mentoring junior scientists, and collaborating effectively with cross-functional teams, including medicinal chemistry, DMPK, and pharmacology. A deep understanding of disease mechanisms and patient populations relevant to our therapeutic areas is essential. You will be responsible for staying abreast of the latest scientific literature and technological advancements in drug discovery, and for proposing innovative approaches to overcome scientific challenges. This position offers a dynamic research environment with access to state-of-the-art facilities and technologies. The role requires a PhD in a relevant life science discipline, coupled with at least 5-7 years of post-doctoral or industry experience. Exceptional analytical and problem-solving skills, along with strong written and verbal communication abilities for presenting findings to internal and external stakeholders, are paramount. Located in the heart of **London, England, UK**, this position operates under a hybrid model, balancing crucial lab-based work with remote data analysis and collaboration. We are committed to fostering a collaborative and intellectually stimulating work environment where innovation thrives and impactful contributions are recognised and rewarded. This is an unparalleled opportunity to shape the future of medicine and make a lasting impact on patient lives.
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Senior Research Scientist - Drug Discovery

SW1A 0AA London, London £75000 Annually WhatJobs

Posted 19 days ago

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full-time
Our client, a pioneering biopharmaceutical company at the forefront of medical innovation, is seeking an accomplished Senior Research Scientist to join their dedicated Scientific Research & Development team. This is a fully remote position, offering the flexibility to contribute to groundbreaking drug discovery efforts from anywhere. You will play a pivotal role in the design, execution, and interpretation of complex experiments aimed at identifying and validating novel therapeutic targets and drug candidates. The Senior Research Scientist will contribute to multiple projects, utilizing cutting-edge technologies and methodologies in areas such as molecular biology, cell biology, and pharmacology. This role demands a deep understanding of disease mechanisms, strong experimental design skills, and the ability to independently analyse and troubleshoot complex data sets. You will collaborate closely with a multidisciplinary team of scientists, clinicians, and project managers, contributing to the progression of drug discovery programs from early-stage research through to preclinical development. We are looking for a highly motivated individual with a passion for scientific discovery, excellent problem-solving capabilities, and strong communication skills. This remote-first role emphasizes proactive communication, meticulous record-keeping, and effective collaboration within a virtual team setting. Our client is committed to advancing human health and offers a stimulating research environment with significant opportunities for career growth and scientific impact.

Key Responsibilities:
  • Design, conduct, and analyse complex experiments to identify and validate drug targets.
  • Develop and optimize assays for high-throughput screening and lead optimization.
  • Utilize advanced techniques in molecular and cell biology, and potentially biochemistry or pharmacology.
  • Interpret experimental data, draw sound conclusions, and propose next steps.
  • Collaborate effectively with cross-functional research teams.
  • Contribute to project strategy and planning for drug discovery programs.
  • Prepare scientific reports, presentations, and contribute to patent applications and publications.
  • Troubleshoot experimental issues and propose solutions.
  • Mentor and guide junior research staff.
Qualifications:
  • PhD in Molecular Biology, Cell Biology, Pharmacology, Biochemistry, or a related life science discipline.
  • Minimum of 5 years of post-doctoral and/or industry experience in drug discovery or a related field.
  • Proven track record of designing and executing complex biological experiments.
  • Extensive experience with relevant experimental techniques (e.g., cell culture, Western blotting, ELISA, qPCR, flow cytometry).
  • Strong understanding of drug discovery processes and principles.
  • Excellent analytical, critical thinking, and problem-solving skills.
  • Proficiency in data analysis software and scientific literature review.
  • Excellent written and oral communication skills, with experience presenting scientific findings.
  • Demonstrated ability to work effectively in a remote, collaborative research environment.
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Lead Research Scientist - Drug Discovery

SW1A 0AA London, London £75000 Annually WhatJobs

Posted 20 days ago

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full-time
Our client, a groundbreaking pharmaceutical company at the forefront of medical innovation, is seeking an accomplished Lead Research Scientist to join their dedicated drug discovery team. This role is critical in driving the identification and validation of novel therapeutic targets and the development of innovative drug candidates. You will be responsible for designing and executing complex research projects, leading a team of talented scientists, and contributing to the strategic direction of the R&D pipeline. The ideal candidate will possess a PhD in a relevant scientific discipline (e.g., Pharmacology, Molecular Biology, Biochemistry), a strong track record of publications and patents, and extensive experience in preclinical drug discovery. Expertise in specific therapeutic areas, assay development, compound screening, and in vivo/in vitro pharmacology is highly desirable. You will foster a collaborative research environment, mentor junior scientists, and effectively communicate research findings to both scientific and non-scientific stakeholders. This position offers the opportunity to make a significant impact on patient lives by advancing novel therapies from concept to clinical trials, working within a state-of-the-art facility located in London, England, UK .

Key Responsibilities:
  • Lead and manage research projects focused on novel drug discovery.
  • Design and implement experimental strategies for target identification and validation.
  • Oversee the development and optimisation of biological assays.
  • Direct compound screening campaigns and lead optimisation efforts.
  • Interpret experimental data and draw conclusions to guide research direction.
  • Mentor and supervise a team of research scientists and technicians.
  • Prepare scientific reports, presentations, and publications.
  • Collaborate with cross-functional teams including chemistry, DMPK, and toxicology.
  • Contribute to the strategic planning of the R&D pipeline.
  • Ensure compliance with all laboratory safety and ethical guidelines.
Qualifications:
  • PhD in Pharmacology, Molecular Biology, Biochemistry, or a related life science field.
  • Minimum of 8 years of post-doctoral research experience in drug discovery within the pharmaceutical or biotech industry.
  • Proven expertise in a specific therapeutic area (e.g., oncology, immunology, CNS).
  • Extensive experience in assay development, high-throughput screening (HTS), and in vitro/in vivo pharmacology.
  • Strong understanding of modern drug discovery methodologies.
  • Excellent scientific leadership, project management, and communication skills.
  • Track record of peer-reviewed publications and/or patent filings.
  • Ability to work effectively in a fast-paced, collaborative research environment.
  • Experience with data analysis software and laboratory information management systems (LIMS).
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Senior Pharmaceutical Research Scientist - Drug Discovery

SW1A 0AA London, London £65000 Annually WhatJobs

Posted 1 day ago

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full-time
Our client is a leading innovator in the pharmaceutical sector, dedicated to advancing human health through cutting-edge research and development. We are seeking a highly skilled and motivated Senior Pharmaceutical Research Scientist to join our dynamic Drug Discovery team based in London, England, UK . This role offers a unique opportunity to contribute to the development of novel therapeutics that address significant unmet medical needs.

The successful candidate will play a pivotal role in designing, executing, and interpreting complex biological experiments to identify and validate potential drug targets. Responsibilities include leading early-stage discovery projects, managing laboratory activities, troubleshooting experimental issues, and contributing to strategic research planning. You will collaborate closely with cross-functional teams, including medicinal chemistry, pharmacology, and translational sciences, to advance promising drug candidates through the development pipeline.

Key responsibilities will involve:
  • Designing and implementing in vitro and in vivo assays to assess target engagement and pharmacological activity.
  • Analyzing and interpreting experimental data, including statistical analysis, and presenting findings to internal stakeholders and at scientific conferences.
  • Staying abreast of the latest scientific literature and technological advancements in drug discovery.
  • Mentoring junior scientists and contributing to a collaborative and innovative research environment.
  • Maintaining accurate and detailed laboratory records in compliance with regulatory standards.
  • Contributing to the preparation of scientific publications and patent applications.
  • Proactively identifying and evaluating new technologies and methodologies to enhance discovery efforts.
  • Ensuring adherence to all safety protocols and laboratory best practices.

The ideal candidate will possess a Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline, with a minimum of 5 years of post-doctoral or industry experience in drug discovery. Proven expertise in assay development, target validation, and a strong understanding of disease biology are essential. Excellent communication, leadership, and problem-solving skills are required. Experience with small molecule drug discovery is highly desirable. Familiarity with relevant regulatory guidelines (e.g., ICH) is a plus. This is an exciting chance to make a significant impact in a globally recognized organization. Join us and be part of a team that is shaping the future of medicine in London, England, UK .
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Senior Pharmaceutical Research Scientist - Drug Discovery

SW1A 0AA London, London £70000 Annually WhatJobs

Posted 2 days ago

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full-time
We are actively seeking a highly skilled and experienced Senior Pharmaceutical Research Scientist to join our cutting-edge drug discovery team. This critical role involves leading innovative research projects focused on identifying and validating novel therapeutic targets and developing groundbreaking medicines. You will be instrumental in driving research initiatives from early-stage discovery through to preclinical development, contributing significantly to our pipeline of life-changing therapies. This is a lab-based role requiring hands-on expertise and scientific leadership.

Responsibilities:
  • Lead and execute complex research projects in drug discovery and development, with a focus on specific therapeutic areas.
  • Design and conduct in vitro and in vivo experiments to assess compound efficacy, safety, and mechanism of action.
  • Analyze and interpret experimental data, troubleshoot technical challenges, and develop innovative solutions.
  • Develop and optimize assays for high-throughput screening (HTS) and lead optimization.
  • Manage project timelines, resources, and budgets, ensuring timely delivery of research milestones.
  • Collaborate effectively with cross-functional teams, including medicinal chemistry, DMPK, toxicology, and clinical development.
  • Stay current with scientific literature and emerging technologies in drug discovery.
  • Prepare and present research findings at internal meetings and external scientific conferences.
  • Contribute to the preparation of regulatory submissions and patent applications.
  • Mentor and guide junior scientists, fostering a culture of scientific excellence and collaboration.
  • Maintain meticulous records of experimental procedures, results, and analyses.
Qualifications:
  • Ph.D. in Pharmacology, Biochemistry, Molecular Biology, or a related life science discipline.
  • Minimum of 5-8 years of post-doctoral or industry experience in pharmaceutical drug discovery.
  • Proven track record of successful research project leadership and delivery.
  • Extensive hands-on experience with a variety of in vitro and in vivo pharmacology techniques.
  • Strong understanding of drug discovery processes and preclinical development.
  • Excellent analytical, problem-solving, and critical thinking skills.
  • Exceptional written and oral communication skills, with a strong publication record.
  • Experience with data analysis software and laboratory information management systems (LIMS).
  • Ability to work independently and lead a team in a collaborative research environment.
  • Deep knowledge of specific therapeutic areas is a significant advantage.
This role represents a key scientific position within our organisation, requiring dedicated on-site presence to drive our drug discovery efforts. You will work within state-of-the-art facilities alongside a team of dedicated researchers committed to advancing human health. The principal site for this research is located in London, England, UK .
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