257 Drug Development jobs in London
Senior Research Scientist - Drug Discovery
Posted 3 days ago
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Job Description
Key Responsibilities:
- Design and implement cutting-edge research projects focused on the identification and validation of novel therapeutic targets.
- Develop and optimize in vitro and ex vivo assays to assess compound efficacy and mechanism of action.
- Conduct rigorous data analysis, interpret experimental results, and generate comprehensive reports.
- Stay abreast of the latest scientific literature, emerging technologies, and competitive landscape in relevant therapeutic areas.
- Collaborate effectively with medicinal chemists, pharmacologists, and other research scientists to advance drug candidates through the discovery pipeline.
- Contribute to the preparation of scientific publications, patents, and regulatory submissions.
- Present research findings at internal meetings and external scientific conferences.
- Troubleshoot experimental challenges and propose innovative solutions.
- Maintain accurate and detailed laboratory notebooks and research records.
- Contribute to the strategic direction of the drug discovery program.
- PhD in Molecular Biology, Cell Biology, Biochemistry, Pharmacology, or a related field.
- Minimum of 5 years of post-doctoral or industry research experience in drug discovery.
- Proven expertise in a range of biological techniques, including but not limited to cell culture, western blotting, ELISA, qPCR, and high-throughput screening.
- Experience with target validation and assay development.
- Strong understanding of disease biology and target engagement.
- Excellent data analysis and interpretation skills.
- Proficiency in scientific writing and presentation.
- Demonstrated ability to work independently and as a productive member of a remote team.
- Strong problem-solving abilities and a creative scientific approach.
- Familiarity with bioinformatics tools is a plus.
Principal Research Scientist - Drug Discovery
Posted 8 days ago
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Job Description
As a Principal Research Scientist, you will lead research projects focused on identifying and validating new drug targets, designing and synthesising novel chemical entities, and advancing lead compounds through preclinical development. Your expertise will be critical in designing and executing complex experiments, interpreting data, and contributing to the strategic direction of drug discovery programmes.
Key Responsibilities:
- Lead and manage independent research projects within drug discovery, from target identification to preclinical candidate selection.
- Design, synthesise, and characterise novel small molecules with therapeutic potential.
- Develop and implement robust experimental assays to evaluate compound efficacy, selectivity, and mechanism of action.
- Conduct detailed data analysis, interpretation, and reporting, presenting findings at internal and external scientific forums.
- Collaborate closely with medicinal chemists, biologists, pharmacologists, and toxicologists to advance drug candidates.
- Provide scientific leadership and mentorship to junior researchers and technicians.
- Stay abreast of the latest scientific literature, technological advancements, and industry trends in pharmaceutical research.
- Contribute to the strategic planning and prioritisation of drug discovery programmes.
- Maintain excellent laboratory practices and ensure compliance with all relevant regulations and safety protocols.
Essential Qualifications:
- PhD in Medicinal Chemistry, Organic Chemistry, Pharmacology, or a related life sciences discipline.
- Minimum of 8 years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
- Proven track record of successfully advancing drug candidates from discovery to preclinical development.
- Extensive experience in synthetic organic chemistry, medicinal chemistry, and assay development.
- Deep understanding of drug discovery processes and a broad knowledge of therapeutic areas.
- Excellent analytical, problem-solving, and critical thinking skills.
- Strong publication record and presentation skills.
- Demonstrated ability to lead research teams and collaborate effectively in a multidisciplinary environment.
- Familiarity with hybrid work models and effective remote collaboration tools.
This is a prestigious opportunity for a seasoned scientist to make a significant impact on patient lives by contributing to the development of next-generation medicines. You will be part of a world-class research organisation, pushing the boundaries of scientific innovation.
Principal Research Scientist, Drug Discovery
Posted 9 days ago
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Lead Research Scientist - Drug Discovery
Posted 10 days ago
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Job Description
Key Responsibilities:
- Lead and manage a team of research scientists involved in early-stage drug discovery projects.
- Design, execute, and interpret complex experiments to identify and validate novel drug targets.
- Develop and implement innovative research strategies and methodologies.
- Oversee the design and synthesis of potential drug molecules, and their preclinical evaluation.
- Collaborate with internal cross-functional teams (e.g., chemistry, biology, DMPK) and external partners to advance projects.
- Analyze and interpret experimental data, present findings at scientific conferences, and contribute to publications.
- Manage research budgets, resources, and timelines effectively.
- Stay abreast of the latest scientific advancements and emerging technologies in pharmaceutical research.
- Mentor and guide junior scientists, fostering a culture of scientific excellence and innovation.
- Ensure all research activities are conducted in compliance with ethical standards and regulatory guidelines.
- Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline.
- Significant postdoctoral and industry experience in drug discovery.
- Proven track record of leading research projects from concept to preclinical development.
- Extensive experience in a specific therapeutic area (e.g., oncology, immunology, neuroscience).
- Expertise in relevant experimental techniques and assays.
- Strong understanding of medicinal chemistry principles and drug development processes.
- Excellent leadership, team management, and communication skills.
- Demonstrated ability to think critically and solve complex scientific problems.
- Experience with grant writing and publications in high-impact journals.
- Proficiency in data analysis software and laboratory information management systems.
Senior Research Scientist - Drug Discovery
Posted 11 days ago
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Job Description
Responsibilities:
- Lead and conduct advanced research projects in drug discovery.
- Design, optimise, and perform complex biological assays.
- Analyse and interpret complex datasets from various experimental platforms.
- Identify and validate novel therapeutic targets.
- Contribute to the optimisation of lead compounds.
- Collaborate effectively with cross-functional research teams.
- Prepare detailed research reports and present findings to stakeholders.
- Stay current with scientific advancements and relevant literature.
- Mentor and guide junior research staff.
- Contribute to the strategic planning of research programs.
- Ensure compliance with ethical and regulatory guidelines.
- PhD in Molecular Biology, Cell Biology, Biochemistry, Pharmacology, or a related field.
- Minimum of 5-7 years of post-doctoral or industry experience in drug discovery.
- Demonstrated expertise in experimental design and execution.
- Strong publication record in peer-reviewed journals.
- Proficiency in relevant biological techniques and instrumentation.
- Experience with computational biology tools and bioinformatics analysis is a plus.
- Excellent problem-solving and critical thinking skills.
- Strong communication and presentation abilities.
- Ability to work independently and manage multiple projects.
- Experience in specific therapeutic areas (e.g., oncology, immunology) is preferred.
- Leadership potential and team-player attitude.
Senior Research Scientist - Drug Discovery
Posted 16 days ago
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Job Description
Senior Research Scientist - Drug Discovery
Posted 19 days ago
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Job Description
Key Responsibilities:
- Design, conduct, and analyse complex experiments to identify and validate drug targets.
- Develop and optimize assays for high-throughput screening and lead optimization.
- Utilize advanced techniques in molecular and cell biology, and potentially biochemistry or pharmacology.
- Interpret experimental data, draw sound conclusions, and propose next steps.
- Collaborate effectively with cross-functional research teams.
- Contribute to project strategy and planning for drug discovery programs.
- Prepare scientific reports, presentations, and contribute to patent applications and publications.
- Troubleshoot experimental issues and propose solutions.
- Mentor and guide junior research staff.
- PhD in Molecular Biology, Cell Biology, Pharmacology, Biochemistry, or a related life science discipline.
- Minimum of 5 years of post-doctoral and/or industry experience in drug discovery or a related field.
- Proven track record of designing and executing complex biological experiments.
- Extensive experience with relevant experimental techniques (e.g., cell culture, Western blotting, ELISA, qPCR, flow cytometry).
- Strong understanding of drug discovery processes and principles.
- Excellent analytical, critical thinking, and problem-solving skills.
- Proficiency in data analysis software and scientific literature review.
- Excellent written and oral communication skills, with experience presenting scientific findings.
- Demonstrated ability to work effectively in a remote, collaborative research environment.
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Lead Research Scientist - Drug Discovery
Posted 20 days ago
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Job Description
Key Responsibilities:
- Lead and manage research projects focused on novel drug discovery.
- Design and implement experimental strategies for target identification and validation.
- Oversee the development and optimisation of biological assays.
- Direct compound screening campaigns and lead optimisation efforts.
- Interpret experimental data and draw conclusions to guide research direction.
- Mentor and supervise a team of research scientists and technicians.
- Prepare scientific reports, presentations, and publications.
- Collaborate with cross-functional teams including chemistry, DMPK, and toxicology.
- Contribute to the strategic planning of the R&D pipeline.
- Ensure compliance with all laboratory safety and ethical guidelines.
- PhD in Pharmacology, Molecular Biology, Biochemistry, or a related life science field.
- Minimum of 8 years of post-doctoral research experience in drug discovery within the pharmaceutical or biotech industry.
- Proven expertise in a specific therapeutic area (e.g., oncology, immunology, CNS).
- Extensive experience in assay development, high-throughput screening (HTS), and in vitro/in vivo pharmacology.
- Strong understanding of modern drug discovery methodologies.
- Excellent scientific leadership, project management, and communication skills.
- Track record of peer-reviewed publications and/or patent filings.
- Ability to work effectively in a fast-paced, collaborative research environment.
- Experience with data analysis software and laboratory information management systems (LIMS).
Senior Pharmaceutical Research Scientist - Drug Discovery
Posted 1 day ago
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Job Description
The successful candidate will play a pivotal role in designing, executing, and interpreting complex biological experiments to identify and validate potential drug targets. Responsibilities include leading early-stage discovery projects, managing laboratory activities, troubleshooting experimental issues, and contributing to strategic research planning. You will collaborate closely with cross-functional teams, including medicinal chemistry, pharmacology, and translational sciences, to advance promising drug candidates through the development pipeline.
Key responsibilities will involve:
- Designing and implementing in vitro and in vivo assays to assess target engagement and pharmacological activity.
- Analyzing and interpreting experimental data, including statistical analysis, and presenting findings to internal stakeholders and at scientific conferences.
- Staying abreast of the latest scientific literature and technological advancements in drug discovery.
- Mentoring junior scientists and contributing to a collaborative and innovative research environment.
- Maintaining accurate and detailed laboratory records in compliance with regulatory standards.
- Contributing to the preparation of scientific publications and patent applications.
- Proactively identifying and evaluating new technologies and methodologies to enhance discovery efforts.
- Ensuring adherence to all safety protocols and laboratory best practices.
The ideal candidate will possess a Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline, with a minimum of 5 years of post-doctoral or industry experience in drug discovery. Proven expertise in assay development, target validation, and a strong understanding of disease biology are essential. Excellent communication, leadership, and problem-solving skills are required. Experience with small molecule drug discovery is highly desirable. Familiarity with relevant regulatory guidelines (e.g., ICH) is a plus. This is an exciting chance to make a significant impact in a globally recognized organization. Join us and be part of a team that is shaping the future of medicine in London, England, UK .
Senior Pharmaceutical Research Scientist - Drug Discovery
Posted 2 days ago
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Job Description
Responsibilities:
- Lead and execute complex research projects in drug discovery and development, with a focus on specific therapeutic areas.
- Design and conduct in vitro and in vivo experiments to assess compound efficacy, safety, and mechanism of action.
- Analyze and interpret experimental data, troubleshoot technical challenges, and develop innovative solutions.
- Develop and optimize assays for high-throughput screening (HTS) and lead optimization.
- Manage project timelines, resources, and budgets, ensuring timely delivery of research milestones.
- Collaborate effectively with cross-functional teams, including medicinal chemistry, DMPK, toxicology, and clinical development.
- Stay current with scientific literature and emerging technologies in drug discovery.
- Prepare and present research findings at internal meetings and external scientific conferences.
- Contribute to the preparation of regulatory submissions and patent applications.
- Mentor and guide junior scientists, fostering a culture of scientific excellence and collaboration.
- Maintain meticulous records of experimental procedures, results, and analyses.
- Ph.D. in Pharmacology, Biochemistry, Molecular Biology, or a related life science discipline.
- Minimum of 5-8 years of post-doctoral or industry experience in pharmaceutical drug discovery.
- Proven track record of successful research project leadership and delivery.
- Extensive hands-on experience with a variety of in vitro and in vivo pharmacology techniques.
- Strong understanding of drug discovery processes and preclinical development.
- Excellent analytical, problem-solving, and critical thinking skills.
- Exceptional written and oral communication skills, with a strong publication record.
- Experience with data analysis software and laboratory information management systems (LIMS).
- Ability to work independently and lead a team in a collaborative research environment.
- Deep knowledge of specific therapeutic areas is a significant advantage.