236 Drug Discovery Scientist jobs in London
Principal Drug Discovery Scientist (Oncology)
Posted 10 days ago
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Job Description
- Lead the design and execution of innovative drug discovery programs targeting various oncological pathways and mechanisms.
- Oversee the identification, validation, and optimization of novel drug targets and lead compounds within the oncology portfolio.
- Manage research projects from target identification through to preclinical candidate selection, ensuring scientific rigor and timely delivery.
- Utilize expertise in cancer biology, medicinal chemistry, and pharmacology to guide experimental strategies and interpret complex data.
- Supervise and mentor a team of talented research scientists and associates, fostering a collaborative and high-performance research environment.
- Develop and implement state-of-the-art assays and screening methodologies relevant to oncology drug discovery.
- Stay abreast of the latest scientific literature, emerging technologies, and competitive landscape in oncology drug development.
- Prepare high-quality scientific reports, publications, and presentations for internal stakeholders and external scientific conferences.
- Collaborate effectively with internal and external partners, including academic institutions and contract research organizations (CROs).
- Contribute to strategic planning and pipeline prioritization for the oncology drug discovery franchise.
- PhD in Cancer Biology, Molecular Pharmacology, Medicinal Chemistry, or a closely related field.
- A minimum of 10 years of progressive drug discovery experience in the pharmaceutical or biotechnology industry, with a strong focus on oncology.
- Demonstrated success in leading drug discovery projects from inception to candidate nomination.
- Expertise in key areas of oncology, including signaling pathways, tumor immunology, or small molecule/biologic therapeutics.
- Proficiency in modern drug discovery techniques, including high-throughput screening (HTS), structure-based drug design, and in vivo efficacy models.
- Proven ability to mentor and manage scientific teams.
- Excellent analytical, critical thinking, and problem-solving skills.
- Strong publication record and experience presenting at international scientific meetings.
- Exceptional communication and interpersonal skills, essential for remote collaboration.
- A genuine passion for advancing cancer treatment and improving patient outcomes.
Principal Scientist - Drug Discovery
Posted 3 days ago
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Job Description
As a Principal Scientist, you will be responsible for designing and executing complex experimental strategies, interpreting data, and drawing robust conclusions. You will contribute to the development of new assays, technologies, and methodologies to advance drug discovery efforts. This role demands a deep understanding of molecular biology, cell biology, pharmacology, or a related discipline, coupled with extensive experience in hypothesis-driven research. You will mentor and guide junior scientists, fostering a collaborative and intellectually stimulating research environment. The ability to critically evaluate scientific literature, identify emerging trends, and translate them into viable research opportunities is essential.
The ideal candidate will possess a PhD in a relevant scientific field, such as molecular biology, biochemistry, immunology, or pharmacology, with a minimum of 8-10 years of post-doctoral and industry experience in drug discovery. A strong publication record in peer-reviewed journals is expected. You should have demonstrated success in leading research projects from conception to completion, with a proven ability to manage resources effectively and deliver results within defined timelines. Excellent communication, presentation, and interpersonal skills are required to effectively collaborate with internal teams, including medicinal chemists, DMPK scientists, and clinicians, as well as external partners and academic collaborators. Experience with specific therapeutic areas such as oncology, immunology, or neuroscience is a significant advantage. This is a challenging yet rewarding opportunity to make a profound impact on patient lives through the development of life-changing medicines. The laboratory facilities are state-of-the-art, providing an ideal environment for groundbreaking research.
Key Responsibilities:
- Lead and design innovative drug discovery research projects.
- Develop and validate novel assays and experimental models.
- Interpret complex biological data and generate actionable insights.
- Mentor and guide junior scientific staff.
- Collaborate with cross-functional teams (chemistry, DMPK, clinical).
- Present research findings at internal meetings and external conferences.
- Stay current with scientific literature and emerging technologies.
- Contribute to intellectual property generation and patent filings.
- Manage project timelines, resources, and budgets.
- Ensure scientific rigor and adherence to company standards.
Principal Scientist - Drug Discovery
Posted 18 days ago
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Job Description
Your core responsibilities will include designing and executing complex experimental studies, utilizing advanced techniques in molecular biology, cell biology, biochemistry, or related fields, relevant to drug discovery. You will critically analyze experimental data, interpret results, and develop innovative approaches to overcome research challenges. The Principal Scientist will be responsible for leading research teams, fostering a collaborative and intellectually stimulating environment, and ensuring the highest standards of scientific rigor and reproducibility. You will manage project timelines, resources, and budgets effectively, and prepare high-quality scientific publications and presentations for both internal and external audiences, including major scientific conferences. A key aspect of the role will involve contributing to the intellectual property strategy and identifying potential drug targets.
The ideal candidate will possess a PhD in a relevant life science discipline (e.g., Molecular Biology, Pharmacology, Biochemistry, Immunology) with a minimum of 8-10 years of post-doctoral experience in the pharmaceutical or biotechnology industry, demonstrating a strong track record of successful drug discovery programs. Proven expertise in a specific therapeutic area (e.g., oncology, neuroscience, infectious diseases) and proficiency in a range of cutting-edge experimental techniques are essential. Exceptional leadership, team management, and strategic thinking skills are required. Outstanding written and verbal communication skills, with the ability to articulate complex scientific concepts clearly and persuasively, are critical. Experience in mentoring junior scientists and managing R&D projects is highly valued. The candidate must be adept at problem-solving and possess a deep understanding of the drug discovery and development process. This is a unique opportunity to join a world-class research team and make a significant contribution to advancing human health. The job location isLondon, England, UK .
Principal Scientist, Drug Discovery
Posted 18 days ago
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Job Description
Key Responsibilities:
- Lead and manage research projects focused on identifying and validating new drug targets and therapeutic modalities.
- Design and implement innovative experimental strategies and methodologies to support drug discovery programs.
- Interpret complex experimental data, draw sound conclusions, and make strategic recommendations for project progression.
- Develop and optimize assays for high-throughput screening (HTS) and lead optimization.
- Collaborate effectively with cross-functional teams, including medicinal chemistry, pharmacology, toxicology, and clinical development.
- Stay abreast of the latest scientific literature, technological advancements, and emerging trends in relevant therapeutic areas.
- Author high-quality scientific publications, patent applications, and regulatory submissions.
- Mentor and guide junior scientists, fostering a collaborative and intellectually stimulating research environment.
- Manage project timelines, budgets, and resources effectively to ensure timely achievement of milestones.
- Present research findings at internal meetings and external scientific conferences.
- Contribute to the strategic direction of the research and development pipeline.
- Ensure compliance with all laboratory safety regulations and best practices.
- Ph.D. in a relevant scientific discipline (e.g., Molecular Biology, Biochemistry, Pharmacology, Genetics).
- Minimum of 10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry, with a strong focus on drug discovery.
- Proven track record of successfully identifying and advancing drug candidates through early development stages.
- Extensive expertise in experimental design, data analysis, and interpretation using a variety of scientific techniques.
- Deep understanding of molecular pathways, disease mechanisms, and therapeutic interventions in specific therapeutic areas (e.g., oncology, immunology, neuroscience).
- Experience with various drug discovery platforms, including small molecules, biologics, or gene therapy.
- Strong leadership, mentorship, and team management skills.
- Excellent written and verbal communication skills, with the ability to present complex scientific information clearly and concisely.
- Proficiency in relevant bioinformatics and computational biology tools is a plus.
- Demonstrated ability to work independently and collaboratively in a remote research setting.
- A passion for scientific innovation and a commitment to bringing life-changing medicines to patients.
Principal Scientist, Drug Discovery
Posted 19 days ago
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Job Description
Key responsibilities include designing and executing complex experiments, developing innovative assays, and interpreting scientific data to guide project strategy. You will mentor and supervise junior scientists, foster a collaborative research environment, and contribute to scientific publications and patent applications. The Principal Scientist will also play a key role in evaluating new technologies and methodologies to enhance drug discovery capabilities. A strong understanding of medicinal chemistry, pharmacology, and disease biology relevant to the client's therapeutic areas is essential. Experience with high-throughput screening (HTS) and compound library management is highly desirable.
The ideal candidate will possess a PhD in a relevant scientific discipline (e.g., Pharmacology, Biochemistry, Molecular Biology) with a minimum of 7 years of post-doctoral research experience in the pharmaceutical or biotechnology industry. Demonstrated leadership in project management and a strong publication record are required. Excellent communication, presentation, and critical thinking skills are paramount. This is an exceptional opportunity for a talented scientist to make a significant impact on the future of medicine within a world-class research organisation.
Senior Pharmaceutical Research Scientist - Drug Discovery
Posted 1 day ago
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Job Description
The successful candidate will play a pivotal role in designing, executing, and interpreting complex biological experiments to identify and validate potential drug targets. Responsibilities include leading early-stage discovery projects, managing laboratory activities, troubleshooting experimental issues, and contributing to strategic research planning. You will collaborate closely with cross-functional teams, including medicinal chemistry, pharmacology, and translational sciences, to advance promising drug candidates through the development pipeline.
Key responsibilities will involve:
- Designing and implementing in vitro and in vivo assays to assess target engagement and pharmacological activity.
- Analyzing and interpreting experimental data, including statistical analysis, and presenting findings to internal stakeholders and at scientific conferences.
- Staying abreast of the latest scientific literature and technological advancements in drug discovery.
- Mentoring junior scientists and contributing to a collaborative and innovative research environment.
- Maintaining accurate and detailed laboratory records in compliance with regulatory standards.
- Contributing to the preparation of scientific publications and patent applications.
- Proactively identifying and evaluating new technologies and methodologies to enhance discovery efforts.
- Ensuring adherence to all safety protocols and laboratory best practices.
The ideal candidate will possess a Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline, with a minimum of 5 years of post-doctoral or industry experience in drug discovery. Proven expertise in assay development, target validation, and a strong understanding of disease biology are essential. Excellent communication, leadership, and problem-solving skills are required. Experience with small molecule drug discovery is highly desirable. Familiarity with relevant regulatory guidelines (e.g., ICH) is a plus. This is an exciting chance to make a significant impact in a globally recognized organization. Join us and be part of a team that is shaping the future of medicine in London, England, UK .
Senior Pharmaceutical Research Scientist - Drug Discovery
Posted 2 days ago
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Job Description
Responsibilities:
- Lead and execute complex research projects in drug discovery and development, with a focus on specific therapeutic areas.
- Design and conduct in vitro and in vivo experiments to assess compound efficacy, safety, and mechanism of action.
- Analyze and interpret experimental data, troubleshoot technical challenges, and develop innovative solutions.
- Develop and optimize assays for high-throughput screening (HTS) and lead optimization.
- Manage project timelines, resources, and budgets, ensuring timely delivery of research milestones.
- Collaborate effectively with cross-functional teams, including medicinal chemistry, DMPK, toxicology, and clinical development.
- Stay current with scientific literature and emerging technologies in drug discovery.
- Prepare and present research findings at internal meetings and external scientific conferences.
- Contribute to the preparation of regulatory submissions and patent applications.
- Mentor and guide junior scientists, fostering a culture of scientific excellence and collaboration.
- Maintain meticulous records of experimental procedures, results, and analyses.
- Ph.D. in Pharmacology, Biochemistry, Molecular Biology, or a related life science discipline.
- Minimum of 5-8 years of post-doctoral or industry experience in pharmaceutical drug discovery.
- Proven track record of successful research project leadership and delivery.
- Extensive hands-on experience with a variety of in vitro and in vivo pharmacology techniques.
- Strong understanding of drug discovery processes and preclinical development.
- Excellent analytical, problem-solving, and critical thinking skills.
- Exceptional written and oral communication skills, with a strong publication record.
- Experience with data analysis software and laboratory information management systems (LIMS).
- Ability to work independently and lead a team in a collaborative research environment.
- Deep knowledge of specific therapeutic areas is a significant advantage.
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Lead Pharmaceutical Research Scientist (Drug Discovery)
Posted 3 days ago
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Job Description
Key Responsibilities:
- Lead and mentor a team of research scientists in all aspects of drug discovery programs.
- Design, develop, and validate novel assays for target identification and validation, and compound screening.
- Oversee the execution of high-throughput screening (HTS) campaigns and hit-to-lead optimization.
- Analyze and interpret complex biological and chemical data, making critical decisions on project progression.
- Collaborate with medicinal chemists, biologists, and pharmacologists to advance drug candidates.
- Contribute to the strategic direction of the drug discovery pipeline, identifying new therapeutic areas and technologies.
- Prepare scientific reports, presentations, and publications for internal and external dissemination.
- Ensure compliance with all relevant safety, ethical, and regulatory guidelines.
- Manage external collaborations with academic institutions and CROs.
- Stay abreast of the latest scientific advancements and emerging technologies in drug discovery.
- Ph.D. in Pharmacology, Biochemistry, Molecular Biology, or a related life science discipline.
- Minimum of 7 years of post-doctoral and/or industry experience in drug discovery.
- Proven track record of successfully progressing drug candidates from discovery through early development.
- Extensive experience with assay development, HTS, and lead optimization strategies.
- Strong understanding of various therapeutic areas and disease biology.
- Proficiency in data analysis software and bioinformatics tools.
- Excellent leadership, team management, and communication skills.
- Ability to work independently and effectively manage projects in a remote setting.
- Strong publication record in reputable peer-reviewed journals.
- A proactive, innovative, and results-oriented mindset.
Senior Pharmaceutical Research Scientist - Drug Discovery
Posted 4 days ago
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Job Description
Key Responsibilities:
- Lead and conduct research projects focused on the discovery and development of novel therapeutics.
- Identify and validate new drug targets using various biological and biochemical methodologies.
- Design, synthesize, and optimize small molecule drug candidates.
- Develop and perform assays for evaluating compound potency, selectivity, and pharmacokinetic properties.
- Analyze experimental data, interpret results, and make recommendations for further research.
- Collaborate with internal and external research partners, including CROs.
- Contribute to the preparation of scientific publications, grant proposals, and patent applications.
- Stay abreast of the latest scientific literature and advancements in drug discovery.
- Mentor and guide junior research scientists and technicians.
- Ensure all research activities are conducted in compliance with ethical standards and regulatory guidelines.
- Ph.D. in Medicinal Chemistry, Pharmacology, Biochemistry, or a related life science discipline.
- Minimum of 6 years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
- Demonstrated success in leading drug discovery projects and a strong publication record.
- Expertise in small molecule drug design, synthesis, and optimization.
- Proficiency in a broad range of biochemical and cellular assay development.
- Strong understanding of pharmacology, ADME/Tox principles, and in vivo study design.
- Excellent analytical, problem-solving, and data interpretation skills.
- Effective written and verbal communication skills, suitable for remote collaboration.
- Proven ability to work independently and manage multiple research priorities.
Lead Pharmaceutical Research Scientist - Drug Discovery
Posted 5 days ago
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Job Description
Responsibilities:
- Lead and manage research projects focused on the discovery and development of novel pharmaceutical agents.
- Design, optimize, and execute complex biochemical, cellular, and in vivo assays to evaluate drug candidates.
- Identify and validate novel drug targets in disease areas of interest.
- Analyze and interpret experimental data, drawing scientifically sound conclusions and making data-driven decisions.
- Collaborate closely with medicinal chemists, pharmacologists, toxicologists, and other R&D scientists in a remote setting.
- Prepare comprehensive research reports, manuscripts for publication, and presentations for scientific conferences.
- Contribute to the strategic direction of the company's drug discovery portfolio.
- Mentor and guide junior research scientists, fostering a collaborative and innovative research environment.
- Ensure compliance with all relevant safety, ethical, and regulatory guidelines.
- Stay abreast of the latest scientific advancements and technological innovations in pharmaceutical research.
- PhD in Pharmacology, Biochemistry, Molecular Biology, or a closely related life science discipline.
- Minimum of 7 years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
- Demonstrated track record of successful drug discovery and development contributions.
- Expertise in (Specific Therapeutic Area - e.g., Oncology, Immunology, Neuroscience) is highly desirable.
- Proficiency in a range of biological and biochemical techniques, including cell culture, high-throughput screening, and animal models.
- Strong understanding of drug discovery processes and regulatory pathways.
- Excellent analytical, problem-solving, and critical thinking skills.
- Exceptional communication, presentation, and interpersonal skills, with the ability to lead and influence.
- Proven ability to manage projects, timelines, and resources effectively in a remote work setting.
- Experience with data analysis software and bioinformatics tools.