Senior Drug Discovery Scientist (Oncology)

SW1A 0AA London, London £60000 Annually WhatJobs

Posted 11 days ago

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full-time
Our client, a pioneering biopharmaceutical company at the forefront of cancer research, is actively recruiting a Senior Drug Discovery Scientist specializing in Oncology to join their fully remote, world-class research team. This role is pivotal in advancing our pipeline of innovative cancer therapeutics, requiring a deep understanding of cancer biology, target validation, and early-stage drug discovery.

Responsibilities:
  • Lead and execute research projects focused on identifying novel oncology targets and developing targeted therapies.
  • Design and implement in vitro and ex vivo assays to evaluate drug candidates for efficacy and mechanism of action.
  • Utilize cutting-edge technologies and methodologies in cancer biology, genomics, and proteomics.
  • Collaborate with medicinal chemists and pharmacologists to optimize lead compounds.
  • Analyze and interpret complex biological data, drawing meaningful conclusions and making strategic recommendations.
  • Prepare high-quality scientific reports, manuscripts for publication, and presentations for internal and external forums.
  • Stay abreast of the latest advancements in oncology research and drug discovery through literature review and conference attendance.
  • Mentor and guide junior scientists, fostering a collaborative and innovative research environment.
  • Contribute to the development of intellectual property, including patent filings.
  • Ensure meticulous experimental design, data integrity, and adherence to laboratory best practices.
Qualifications:
  • PhD in Cancer Biology, Molecular Biology, Pharmacology, or a closely related field.
  • A minimum of 5 years of post-doctoral or industry experience in oncology drug discovery.
  • Proven expertise in cancer cell biology, tumor microenvironment, or immunotherapy.
  • Hands-on experience with a variety of cellular assays, molecular biology techniques, and potentially in vivo models.
  • Strong understanding of small molecule and/or biologics drug discovery processes.
  • Demonstrated ability to design, execute, and interpret complex experiments.
  • Excellent analytical and problem-solving skills.
  • Exceptional written and oral communication skills, with a strong publication record in reputable journals.
  • Ability to work independently and lead projects in a remote setting.
  • A passion for advancing cancer treatment and a commitment to scientific rigor.
This fully remote position offers an exceptional opportunity to contribute to life-saving research, collaborate with leading experts, and drive innovation in the fight against cancer, all within a flexible and stimulating work environment.
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Principal Scientist, Drug Discovery

SW1A 0AA London, London £75000 Annually WhatJobs

Posted 3 days ago

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full-time
Our client, a leading innovator in the pharmaceutical sector, is seeking a highly experienced Principal Scientist to join their prestigious Research & Development team. This hybrid role, based in London, England, UK , offers the opportunity to contribute to groundbreaking drug discovery initiatives. The Principal Scientist will lead ambitious research projects, driving the identification and validation of novel therapeutic targets and small molecule leads.

Key responsibilities include designing and executing complex experiments, developing innovative assays, and interpreting scientific data to guide project strategy. You will mentor and supervise junior scientists, foster a collaborative research environment, and contribute to scientific publications and patent applications. The Principal Scientist will also play a key role in evaluating new technologies and methodologies to enhance drug discovery capabilities. A strong understanding of medicinal chemistry, pharmacology, and disease biology relevant to the client's therapeutic areas is essential. Experience with high-throughput screening (HTS) and compound library management is highly desirable.

The ideal candidate will possess a PhD in a relevant scientific discipline (e.g., Pharmacology, Biochemistry, Molecular Biology) with a minimum of 7 years of post-doctoral research experience in the pharmaceutical or biotechnology industry. Demonstrated leadership in project management and a strong publication record are required. Excellent communication, presentation, and critical thinking skills are paramount. This is an exceptional opportunity for a talented scientist to make a significant impact on the future of medicine within a world-class research organisation.
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Principal Scientist, Drug Discovery

SW1A 0AA London, London £85000 Annually WhatJobs

Posted 10 days ago

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full-time
Our client is a world-leading biotechnology company at the forefront of pharmaceutical innovation. They are seeking an exceptional Principal Scientist to drive critical research initiatives within their drug discovery division. This is a fully remote position, offering a unique opportunity to shape the future of medicine from your home laboratory or office. You will be responsible for leading complex research projects, developing novel therapeutic strategies, and contributing to the advancement of our preclinical and clinical pipelines. Key responsibilities include designing and executing sophisticated experiments, analysing complex biological data, and interpreting results to guide project direction. You will be expected to identify and validate new drug targets, develop innovative assay methodologies, and contribute to the preclinical characterisation of drug candidates. Collaboration with internal multidisciplinary teams, including medicinal chemists, pharmacologists, and clinical researchers, as well as external academic partners, will be essential. The ideal candidate will possess a deep understanding of molecular biology, pharmacology, or a related field, with a strong publication record and extensive experience in drug discovery. Proven experience in leading research projects, mentoring junior scientists, and contributing to strategic R&D decisions is highly desirable. You should be adept at critical thinking, possess excellent problem-solving skills, and be passionate about scientific advancement. As a remote role, outstanding communication, presentation, and self-management skills are crucial for effective collaboration and leadership. This role offers a challenging and rewarding opportunity to make a significant impact on patient lives through cutting-edge scientific research.

Key Responsibilities:
  • Lead and design complex research projects in drug discovery.
  • Develop and implement novel scientific methodologies and assays.
  • Identify and validate potential drug targets and therapeutic strategies.
  • Conduct in-depth analysis of biological and pharmacological data.
  • Interpret experimental results and guide project progression.
  • Collaborate with internal and external research teams and stakeholders.
  • Mentor and supervise junior scientific staff.
  • Contribute to the strategic direction of the R&D pipeline.
  • Author scientific publications and present research findings.
  • Ensure compliance with safety and ethical research standards.

Qualifications:
  • PhD in Molecular Biology, Pharmacology, Biochemistry, or a related life science discipline.
  • Minimum of 8 years of post-doctoral research experience in drug discovery or a related field.
  • Proven track record of leading successful research projects and publications in high-impact journals.
  • Extensive experience in experimental design, execution, and data analysis.
  • Expertise in relevant therapeutic areas and/or scientific disciplines (e.g., oncology, immunology, neuroscience).
  • Demonstrated leadership, mentoring, and project management skills.
  • Excellent analytical, critical thinking, and problem-solving abilities.
  • Outstanding written and verbal communication and presentation skills.
  • Experience working independently and collaboratively in a remote research setting.
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Principal Scientist - Drug Discovery

SW1A 0 London, London £80000 Annually WhatJobs

Posted 15 days ago

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full-time
Our client is seeking a highly accomplished Principal Scientist to lead groundbreaking research and development initiatives within their cutting-edge drug discovery division, located in London, England, UK . This senior scientific role demands exceptional expertise in molecular biology, pharmacology, or a related life science discipline, with a proven track record of successfully advancing therapeutic candidates from early discovery through to pre-clinical development. You will be responsible for designing and executing complex experimental strategies, interpreting data, and mentoring a team of talented scientists. This is a critical role contributing to the development of novel treatments for unmet medical needs. Key responsibilities include:
  • Leading and directing research programs focused on identifying and validating novel drug targets and developing therapeutic agents.
  • Designing, implementing, and optimizing complex experimental assays and workflows.
  • Interpreting experimental data, drawing robust conclusions, and communicating findings to internal and external stakeholders.
  • Developing and managing project timelines, resources, and budgets.
  • Mentoring and guiding junior scientists, fostering a collaborative and innovative research environment.
  • Writing scientific publications, patent applications, and regulatory submissions.
  • Collaborating closely with other scientific disciplines, including medicinal chemistry, DMPK, and translational science.
  • Evaluating new technologies and methodologies to enhance discovery capabilities.
  • Ensuring compliance with all safety, ethical, and regulatory guidelines.

A PhD in Molecular Biology, Pharmacology, Biochemistry, or a closely related field is mandatory, coupled with substantial post-doctoral and industry experience in drug discovery. Demonstrated expertise in a specific therapeutic area (e.g., oncology, immunology, neuroscience) is highly desirable. Excellent leadership, communication, and critical thinking skills are essential. The successful candidate will have a passion for scientific innovation and a commitment to driving meaningful advancements in medicine, working within a world-class research facility in the heart of London .
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Principal Scientist, Drug Discovery

W1A 0AX London, London £75000 Annually WhatJobs

Posted 16 days ago

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full-time
Our client, a pioneering biopharmaceutical company, is seeking a highly accomplished Principal Scientist to join their world-class Scientific Research & Development team in London, England, UK . This pivotal role will focus on driving cutting-edge research in drug discovery and development. You will lead projects aimed at identifying and validating novel therapeutic targets, designing and synthesizing small molecules or biologics, and advancing potential drug candidates through preclinical stages. This position requires extensive expertise in molecular biology, pharmacology, or a related discipline, along with a strong publication record.

Key responsibilities include designing and executing complex research experiments, interpreting data, and contributing to the strategic direction of discovery programs. You will collaborate with cross-functional teams, including medicinal chemists, computational biologists, and toxicologists, to overcome scientific challenges and accelerate the drug development pipeline. The Principal Scientist will also be responsible for mentoring junior researchers, staying abreast of the latest scientific literature, and presenting findings at internal and external conferences. A deep understanding of disease mechanisms and the ability to translate scientific insights into actionable research plans are essential.

The ideal candidate will hold a PhD in a relevant scientific discipline (e.g., Molecular Biology, Biochemistry, Pharmacology, Chemistry) and possess a minimum of 7 years of post-doctoral research experience in the pharmaceutical or biotechnology industry. A proven track record of success in drug discovery, evidenced by peer-reviewed publications and successful progression of projects, is required. Strong analytical and problem-solving skills, coupled with excellent written and verbal communication abilities, are crucial. Experience in leading research teams and managing complex scientific projects is highly valued. This is an exceptional opportunity to make a significant impact on the future of medicine and contribute to life-saving therapies.

Qualifications:
  • PhD in Molecular Biology, Biochemistry, Pharmacology, Chemistry, or a related field.
  • Minimum of 7 years of post-doctoral research experience in the pharmaceutical/biotech industry.
  • Proven track record in drug discovery and development.
  • Extensive experience in experimental design, execution, and data analysis.
  • Strong publication record in peer-reviewed journals.
  • Expertise in relevant therapeutic areas or research methodologies.
  • Excellent communication, leadership, and collaboration skills.
  • Ability to mentor and guide junior scientists.
  • Experience in project leadership and strategic planning.
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Senior Pharmaceutical Research Scientist - Drug Discovery

SW1A 0AA London, London £70000 Annually WhatJobs

Posted today

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full-time
Our client, a leading biopharmaceutical company, is seeking an innovative and highly skilled Senior Pharmaceutical Research Scientist to join their dynamic Drug Discovery team in London, England, UK . This role offers an exciting opportunity to contribute to the development of novel therapeutics for unmet medical needs. You will be instrumental in designing and executing cutting-edge research programs, focusing on target identification, validation, and hit-to-lead optimization. The Senior Scientist will leverage their expertise in molecular biology, pharmacology, and drug development to drive projects forward from early discovery through to pre-clinical development. Key responsibilities include designing and implementing in vitro and in vivo assays, analysing complex biological data, and interpreting results to guide experimental direction. You will collaborate closely with cross-functional teams, including chemists, computational biologists, and translational scientists, to achieve project milestones. The ideal candidate will possess a PhD in a relevant scientific discipline, a strong publication record, and extensive experience in pharmaceutical research and drug discovery. Expertise in specific therapeutic areas (e.g., oncology, immunology, neuroscience) is highly desirable. You will be expected to contribute to intellectual property generation, scientific presentations, and regulatory filings. Strong problem-solving skills, excellent communication abilities, and a passion for scientific innovation are essential. This is a challenging and rewarding position for a dedicated scientist seeking to make a significant impact on the future of medicine.
Responsibilities:
  • Design, develop, and execute innovative drug discovery research programs.
  • Lead projects focused on target identification, validation, and hit-to-lead optimization.
  • Develop and implement complex in vitro and in vivo biological assays.
  • Analyze and interpret experimental data, drawing conclusions to guide project strategy.
  • Collaborate effectively with multidisciplinary teams, including medicinal chemists and biologists.
  • Contribute to the design of pre-clinical development strategies.
  • Maintain a deep understanding of scientific literature and emerging technologies in relevant therapeutic areas.
  • Document research findings meticulously and contribute to patents and publications.
  • Present research findings at internal and external scientific meetings.
  • Mentor junior scientists and provide technical guidance.
  • Ensure compliance with laboratory safety standards and company policies.
  • Contribute to the overall scientific strategy of the drug discovery unit.
Qualifications:
  • PhD in Pharmacology, Molecular Biology, Biochemistry, or a related field.
  • Minimum of 5 years of post-doctoral or industry research experience in drug discovery.
  • Demonstrated expertise in designing and executing biological assays relevant to drug discovery.
  • Proven track record of scientific achievement, evidenced by publications and presentations.
  • Experience in specific therapeutic areas such as oncology, immunology, or neuroscience is a strong asset.
  • Proficiency in data analysis and scientific software.
  • Excellent problem-solving, critical thinking, and experimental design skills.
  • Strong written and verbal communication skills.
  • Ability to work independently and collaboratively in a fast-paced research environment.
  • Experience with small molecule or biologic drug development is preferred.
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Senior Pharmaceutical Research Scientist (Drug Discovery)

WC2B 4LD London, London £60000 Annually WhatJobs

Posted 2 days ago

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Job Description

full-time
Our client, a prestigious pharmaceutical company at the forefront of medical innovation, is seeking a highly skilled Senior Pharmaceutical Research Scientist to join their dedicated drug discovery team. This is a fully remote position, offering the flexibility to contribute to groundbreaking research from anywhere. You will be integral in identifying, validating, and advancing novel therapeutic targets and small molecules to develop life-changing medicines. Your expertise in molecular biology, pharmacology, and assay development will be crucial in driving our discovery pipeline forward.

Key Responsibilities:
  • Design, execute, and interpret complex experiments to identify and validate potential drug targets and novel therapeutic compounds.
  • Develop and optimize robust biochemical and cellular assays for high-throughput screening (HTS) and lead characterization.
  • Utilize cutting-edge technologies and methodologies in molecular biology, biochemistry, and pharmacology.
  • Analyze experimental data using appropriate statistical methods and scientific software.
  • Manage and interpret large datasets, presenting findings clearly and concisely in reports and presentations.
  • Collaborate closely with cross-functional teams, including medicinal chemists, pharmacologists, and toxicologists, to advance drug candidates.
  • Stay current with the latest scientific literature, emerging technologies, and industry trends in drug discovery.
  • Contribute to the development of research strategies and project planning.
  • Mentor and guide junior research associates and scientists.
  • Maintain accurate and detailed laboratory records.
  • Ensure compliance with all laboratory safety regulations and company policies.
Qualifications:
  • Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline.
  • Minimum of 5 years of post-doctoral research experience in pharmaceutical drug discovery or a related field.
  • Proven track record of successfully identifying and validating drug targets and advancing preclinical candidates.
  • Extensive experience in assay development, optimization, and execution (e.g., enzyme assays, cell-based assays, HTS).
  • Strong understanding of molecular biology techniques and signal transduction pathways.
  • Proficiency in data analysis software (e.g., GraphPad Prism, JMP) and scientific literature databases.
  • Excellent scientific writing and presentation skills.
  • Ability to work independently, manage multiple projects, and collaborate effectively within a remote research team.
  • Experience in a specific therapeutic area (e.g., oncology, immunology, neuroscience) is a plus.
  • Demonstrated ability to think critically and creatively solve complex scientific problems.
This is an exceptional opportunity to contribute to impactful drug discovery research in a flexible, remote setting. We offer a competitive compensation package and the chance to be part of a world-class scientific organization.
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Principal Pharmaceutical Research Scientist (Drug Discovery)

SW1A 0AA London, London £70000 Annually WhatJobs

Posted 3 days ago

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Job Description

full-time
A leading pharmaceutical research organization in London, England, UK is looking for an exceptional Principal Pharmaceutical Research Scientist to spearhead groundbreaking drug discovery initiatives. This is a unique opportunity to join a world-class team dedicated to developing innovative therapies for unmet medical needs. As a Principal Scientist, you will lead research projects from conception to preclinical development, contributing significantly to the company's pipeline.

Key Responsibilities:
  • Design and execute complex research experiments to identify and validate novel drug targets and therapeutic candidates.
  • Lead a team of scientists and technicians, providing mentorship and technical guidance.
  • Develop and implement cutting-edge research methodologies in areas such as molecular biology, pharmacology, or medicinal chemistry.
  • Analyze and interpret experimental data, drawing sound conclusions and making strategic recommendations.
  • Author high-quality scientific publications and present findings at international conferences.
  • Collaborate with cross-functional teams, including clinical development, regulatory affairs, and manufacturing.
  • Manage research projects, ensuring timely completion within budget and scope.
  • Contribute to intellectual property generation through patent filings.
  • Stay abreast of the latest scientific literature and technological advancements in drug discovery.
  • Maintain a safe and compliant laboratory environment.

The ideal candidate will hold a PhD in a relevant scientific discipline (e.g., pharmacology, molecular biology, biochemistry, chemistry) and possess a minimum of 8-10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry. Proven expertise in leading drug discovery projects, a strong publication record, and excellent leadership and communication skills are essential. Experience with hybrid work models, balancing on-site laboratory work with remote data analysis and collaboration, is expected. This role offers a competitive salary and benefits package, along with the opportunity to make a profound impact on global health. Join our innovative team in London and help shape the future of medicine.
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Senior Pharmaceutical Research Scientist - Drug Discovery

SW1A 0AA London, London £65000 Annually WhatJobs

Posted 5 days ago

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full-time
Our client is seeking a highly motivated and experienced Senior Pharmaceutical Research Scientist to join their innovative drug discovery team in London, England, UK . This pivotal role will involve designing, executing, and analyzing complex experiments to identify and validate novel therapeutic targets. You will be instrumental in the early-stage development of groundbreaking medicines, contributing to projects across various disease areas. The successful candidate will possess a deep understanding of molecular biology, biochemistry, and pharmacology, with a proven track record in a pharmaceutical or biotechnology research setting. Responsibilities include leading research projects, mentoring junior scientists, developing and optimizing assays, interpreting experimental data, and presenting findings to internal stakeholders and external collaborators. This is a fantastic opportunity to make a significant impact in the pharmaceutical industry and advance your career within a dynamic and collaborative environment. The ideal candidate will have a PhD in a relevant scientific discipline, with a minimum of 5 years of post-doctoral or industry experience. Essential skills include strong analytical and problem-solving abilities, excellent written and verbal communication skills, and proficiency in data analysis software. Experience with high-throughput screening (HTS), in vivo models, or specific therapeutic areas (e.g., oncology, immunology, neurology) would be a significant advantage. Join a forward-thinking organization dedicated to improving patient lives through scientific excellence. We are committed to fostering a diverse and inclusive workplace where innovation thrives.
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Senior Pharmaceutical Research Scientist - Drug Discovery

WC1A 0AA London, London £70000 Annually WhatJobs

Posted 5 days ago

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full-time
Our client, a world-renowned pharmaceutical company, is seeking a highly skilled and dedicated Senior Pharmaceutical Research Scientist to join their innovative drug discovery team. This vital on-site role is integral to the identification and development of novel therapeutic agents. You will lead research projects, design and execute complex experiments, and contribute to the preclinical development of new drug candidates. The ideal candidate will possess extensive experience in pharmaceutical research, a deep understanding of molecular biology and pharmacology, and a passion for advancing human health.

Responsibilities:
  • Lead and manage research projects focused on the discovery and characterization of novel drug targets and lead compounds.
  • Design, optimize, and execute complex in vitro and in vivo experiments to assess compound efficacy, safety, and pharmacokinetics.
  • Analyze and interpret experimental data, drawing robust conclusions and making recommendations for project progression.
  • Develop and implement cutting-edge assays and methodologies relevant to drug discovery.
  • Collaborate effectively with multidisciplinary teams, including medicinal chemists, pharmacologists, toxicologists, and formulation scientists.
  • Contribute to the preparation of scientific publications, patents, and regulatory submissions.
  • Mentor and guide junior research scientists, fostering their technical and scientific development.
  • Maintain detailed and accurate laboratory records, adhering to GLP standards where applicable.
  • Stay abreast of the latest scientific advancements and emerging technologies in drug discovery and relevant therapeutic areas.
  • Present research findings at internal and external scientific conferences.
  • Ensure compliance with all laboratory safety protocols and ethical guidelines.
  • Contribute to the strategic direction of the drug discovery pipeline.

Qualifications:
  • Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a closely related field.
  • Minimum of 7 years of post-doctoral or industry experience in pharmaceutical drug discovery.
  • Proven track record of successfully identifying and advancing drug candidates through preclinical development.
  • Extensive experience with a range of in vitro and in vivo pharmacology models and assays.
  • Deep understanding of drug discovery processes, medicinal chemistry principles, and regulatory requirements.
  • Strong analytical, problem-solving, and critical thinking skills.
  • Excellent scientific writing and oral communication skills, with the ability to present complex data clearly.
  • Demonstrated leadership abilities and experience mentoring junior scientists.
  • Proficiency with relevant scientific software and data analysis tools.
  • Ability to work independently and as part of a collaborative, high-performing team.
  • Commitment to scientific rigor and ethical research practices.
This demanding on-site position, based at our state-of-the-art research facilities in **London, England, UK**, is a significant opportunity to contribute to life-changing medicines.
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