238 Drug Discovery jobs in London
Principal Scientist - Drug Discovery
Posted 3 days ago
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As a Principal Scientist, you will be responsible for designing and executing complex experimental strategies, interpreting data, and drawing robust conclusions. You will contribute to the development of new assays, technologies, and methodologies to advance drug discovery efforts. This role demands a deep understanding of molecular biology, cell biology, pharmacology, or a related discipline, coupled with extensive experience in hypothesis-driven research. You will mentor and guide junior scientists, fostering a collaborative and intellectually stimulating research environment. The ability to critically evaluate scientific literature, identify emerging trends, and translate them into viable research opportunities is essential.
The ideal candidate will possess a PhD in a relevant scientific field, such as molecular biology, biochemistry, immunology, or pharmacology, with a minimum of 8-10 years of post-doctoral and industry experience in drug discovery. A strong publication record in peer-reviewed journals is expected. You should have demonstrated success in leading research projects from conception to completion, with a proven ability to manage resources effectively and deliver results within defined timelines. Excellent communication, presentation, and interpersonal skills are required to effectively collaborate with internal teams, including medicinal chemists, DMPK scientists, and clinicians, as well as external partners and academic collaborators. Experience with specific therapeutic areas such as oncology, immunology, or neuroscience is a significant advantage. This is a challenging yet rewarding opportunity to make a profound impact on patient lives through the development of life-changing medicines. The laboratory facilities are state-of-the-art, providing an ideal environment for groundbreaking research.
Key Responsibilities:
- Lead and design innovative drug discovery research projects.
- Develop and validate novel assays and experimental models.
- Interpret complex biological data and generate actionable insights.
- Mentor and guide junior scientific staff.
- Collaborate with cross-functional teams (chemistry, DMPK, clinical).
- Present research findings at internal meetings and external conferences.
- Stay current with scientific literature and emerging technologies.
- Contribute to intellectual property generation and patent filings.
- Manage project timelines, resources, and budgets.
- Ensure scientific rigor and adherence to company standards.
Principal Scientist - Drug Discovery
Posted 18 days ago
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Your core responsibilities will include designing and executing complex experimental studies, utilizing advanced techniques in molecular biology, cell biology, biochemistry, or related fields, relevant to drug discovery. You will critically analyze experimental data, interpret results, and develop innovative approaches to overcome research challenges. The Principal Scientist will be responsible for leading research teams, fostering a collaborative and intellectually stimulating environment, and ensuring the highest standards of scientific rigor and reproducibility. You will manage project timelines, resources, and budgets effectively, and prepare high-quality scientific publications and presentations for both internal and external audiences, including major scientific conferences. A key aspect of the role will involve contributing to the intellectual property strategy and identifying potential drug targets.
The ideal candidate will possess a PhD in a relevant life science discipline (e.g., Molecular Biology, Pharmacology, Biochemistry, Immunology) with a minimum of 8-10 years of post-doctoral experience in the pharmaceutical or biotechnology industry, demonstrating a strong track record of successful drug discovery programs. Proven expertise in a specific therapeutic area (e.g., oncology, neuroscience, infectious diseases) and proficiency in a range of cutting-edge experimental techniques are essential. Exceptional leadership, team management, and strategic thinking skills are required. Outstanding written and verbal communication skills, with the ability to articulate complex scientific concepts clearly and persuasively, are critical. Experience in mentoring junior scientists and managing R&D projects is highly valued. The candidate must be adept at problem-solving and possess a deep understanding of the drug discovery and development process. This is a unique opportunity to join a world-class research team and make a significant contribution to advancing human health. The job location isLondon, England, UK .
Principal Scientist, Drug Discovery
Posted 18 days ago
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Job Description
Key Responsibilities:
- Lead and manage research projects focused on identifying and validating new drug targets and therapeutic modalities.
- Design and implement innovative experimental strategies and methodologies to support drug discovery programs.
- Interpret complex experimental data, draw sound conclusions, and make strategic recommendations for project progression.
- Develop and optimize assays for high-throughput screening (HTS) and lead optimization.
- Collaborate effectively with cross-functional teams, including medicinal chemistry, pharmacology, toxicology, and clinical development.
- Stay abreast of the latest scientific literature, technological advancements, and emerging trends in relevant therapeutic areas.
- Author high-quality scientific publications, patent applications, and regulatory submissions.
- Mentor and guide junior scientists, fostering a collaborative and intellectually stimulating research environment.
- Manage project timelines, budgets, and resources effectively to ensure timely achievement of milestones.
- Present research findings at internal meetings and external scientific conferences.
- Contribute to the strategic direction of the research and development pipeline.
- Ensure compliance with all laboratory safety regulations and best practices.
- Ph.D. in a relevant scientific discipline (e.g., Molecular Biology, Biochemistry, Pharmacology, Genetics).
- Minimum of 10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry, with a strong focus on drug discovery.
- Proven track record of successfully identifying and advancing drug candidates through early development stages.
- Extensive expertise in experimental design, data analysis, and interpretation using a variety of scientific techniques.
- Deep understanding of molecular pathways, disease mechanisms, and therapeutic interventions in specific therapeutic areas (e.g., oncology, immunology, neuroscience).
- Experience with various drug discovery platforms, including small molecules, biologics, or gene therapy.
- Strong leadership, mentorship, and team management skills.
- Excellent written and verbal communication skills, with the ability to present complex scientific information clearly and concisely.
- Proficiency in relevant bioinformatics and computational biology tools is a plus.
- Demonstrated ability to work independently and collaboratively in a remote research setting.
- A passion for scientific innovation and a commitment to bringing life-changing medicines to patients.
Principal Scientist, Drug Discovery
Posted 19 days ago
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Job Description
Key responsibilities include designing and executing complex experiments, developing innovative assays, and interpreting scientific data to guide project strategy. You will mentor and supervise junior scientists, foster a collaborative research environment, and contribute to scientific publications and patent applications. The Principal Scientist will also play a key role in evaluating new technologies and methodologies to enhance drug discovery capabilities. A strong understanding of medicinal chemistry, pharmacology, and disease biology relevant to the client's therapeutic areas is essential. Experience with high-throughput screening (HTS) and compound library management is highly desirable.
The ideal candidate will possess a PhD in a relevant scientific discipline (e.g., Pharmacology, Biochemistry, Molecular Biology) with a minimum of 7 years of post-doctoral research experience in the pharmaceutical or biotechnology industry. Demonstrated leadership in project management and a strong publication record are required. Excellent communication, presentation, and critical thinking skills are paramount. This is an exceptional opportunity for a talented scientist to make a significant impact on the future of medicine within a world-class research organisation.
Senior Research Scientist - Drug Discovery
Posted 2 days ago
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Job Description
Key Responsibilities:
- Design and implement cutting-edge research projects focused on the identification and validation of novel therapeutic targets.
- Develop and optimize in vitro and ex vivo assays to assess compound efficacy and mechanism of action.
- Conduct rigorous data analysis, interpret experimental results, and generate comprehensive reports.
- Stay abreast of the latest scientific literature, emerging technologies, and competitive landscape in relevant therapeutic areas.
- Collaborate effectively with medicinal chemists, pharmacologists, and other research scientists to advance drug candidates through the discovery pipeline.
- Contribute to the preparation of scientific publications, patents, and regulatory submissions.
- Present research findings at internal meetings and external scientific conferences.
- Troubleshoot experimental challenges and propose innovative solutions.
- Maintain accurate and detailed laboratory notebooks and research records.
- Contribute to the strategic direction of the drug discovery program.
- PhD in Molecular Biology, Cell Biology, Biochemistry, Pharmacology, or a related field.
- Minimum of 5 years of post-doctoral or industry research experience in drug discovery.
- Proven expertise in a range of biological techniques, including but not limited to cell culture, western blotting, ELISA, qPCR, and high-throughput screening.
- Experience with target validation and assay development.
- Strong understanding of disease biology and target engagement.
- Excellent data analysis and interpretation skills.
- Proficiency in scientific writing and presentation.
- Demonstrated ability to work independently and as a productive member of a remote team.
- Strong problem-solving abilities and a creative scientific approach.
- Familiarity with bioinformatics tools is a plus.
Principal Research Scientist - Drug Discovery
Posted 8 days ago
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Job Description
As a Principal Research Scientist, you will lead research projects focused on identifying and validating new drug targets, designing and synthesising novel chemical entities, and advancing lead compounds through preclinical development. Your expertise will be critical in designing and executing complex experiments, interpreting data, and contributing to the strategic direction of drug discovery programmes.
Key Responsibilities:
- Lead and manage independent research projects within drug discovery, from target identification to preclinical candidate selection.
- Design, synthesise, and characterise novel small molecules with therapeutic potential.
- Develop and implement robust experimental assays to evaluate compound efficacy, selectivity, and mechanism of action.
- Conduct detailed data analysis, interpretation, and reporting, presenting findings at internal and external scientific forums.
- Collaborate closely with medicinal chemists, biologists, pharmacologists, and toxicologists to advance drug candidates.
- Provide scientific leadership and mentorship to junior researchers and technicians.
- Stay abreast of the latest scientific literature, technological advancements, and industry trends in pharmaceutical research.
- Contribute to the strategic planning and prioritisation of drug discovery programmes.
- Maintain excellent laboratory practices and ensure compliance with all relevant regulations and safety protocols.
Essential Qualifications:
- PhD in Medicinal Chemistry, Organic Chemistry, Pharmacology, or a related life sciences discipline.
- Minimum of 8 years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
- Proven track record of successfully advancing drug candidates from discovery to preclinical development.
- Extensive experience in synthetic organic chemistry, medicinal chemistry, and assay development.
- Deep understanding of drug discovery processes and a broad knowledge of therapeutic areas.
- Excellent analytical, problem-solving, and critical thinking skills.
- Strong publication record and presentation skills.
- Demonstrated ability to lead research teams and collaborate effectively in a multidisciplinary environment.
- Familiarity with hybrid work models and effective remote collaboration tools.
This is a prestigious opportunity for a seasoned scientist to make a significant impact on patient lives by contributing to the development of next-generation medicines. You will be part of a world-class research organisation, pushing the boundaries of scientific innovation.
Principal Research Scientist, Drug Discovery
Posted 8 days ago
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Lead Research Scientist - Drug Discovery
Posted 10 days ago
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Key Responsibilities:
- Lead and manage a team of research scientists involved in early-stage drug discovery projects.
- Design, execute, and interpret complex experiments to identify and validate novel drug targets.
- Develop and implement innovative research strategies and methodologies.
- Oversee the design and synthesis of potential drug molecules, and their preclinical evaluation.
- Collaborate with internal cross-functional teams (e.g., chemistry, biology, DMPK) and external partners to advance projects.
- Analyze and interpret experimental data, present findings at scientific conferences, and contribute to publications.
- Manage research budgets, resources, and timelines effectively.
- Stay abreast of the latest scientific advancements and emerging technologies in pharmaceutical research.
- Mentor and guide junior scientists, fostering a culture of scientific excellence and innovation.
- Ensure all research activities are conducted in compliance with ethical standards and regulatory guidelines.
- Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline.
- Significant postdoctoral and industry experience in drug discovery.
- Proven track record of leading research projects from concept to preclinical development.
- Extensive experience in a specific therapeutic area (e.g., oncology, immunology, neuroscience).
- Expertise in relevant experimental techniques and assays.
- Strong understanding of medicinal chemistry principles and drug development processes.
- Excellent leadership, team management, and communication skills.
- Demonstrated ability to think critically and solve complex scientific problems.
- Experience with grant writing and publications in high-impact journals.
- Proficiency in data analysis software and laboratory information management systems.
Senior Research Scientist - Drug Discovery
Posted 11 days ago
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Job Description
Responsibilities:
- Lead and conduct advanced research projects in drug discovery.
- Design, optimise, and perform complex biological assays.
- Analyse and interpret complex datasets from various experimental platforms.
- Identify and validate novel therapeutic targets.
- Contribute to the optimisation of lead compounds.
- Collaborate effectively with cross-functional research teams.
- Prepare detailed research reports and present findings to stakeholders.
- Stay current with scientific advancements and relevant literature.
- Mentor and guide junior research staff.
- Contribute to the strategic planning of research programs.
- Ensure compliance with ethical and regulatory guidelines.
- PhD in Molecular Biology, Cell Biology, Biochemistry, Pharmacology, or a related field.
- Minimum of 5-7 years of post-doctoral or industry experience in drug discovery.
- Demonstrated expertise in experimental design and execution.
- Strong publication record in peer-reviewed journals.
- Proficiency in relevant biological techniques and instrumentation.
- Experience with computational biology tools and bioinformatics analysis is a plus.
- Excellent problem-solving and critical thinking skills.
- Strong communication and presentation abilities.
- Ability to work independently and manage multiple projects.
- Experience in specific therapeutic areas (e.g., oncology, immunology) is preferred.
- Leadership potential and team-player attitude.
Senior Research Scientist - Drug Discovery
Posted 16 days ago
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