46 Drug Discovery jobs in London
Principal Research Scientist, Drug Discovery
Posted 1 day ago
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Key responsibilities include:
- Leading innovative research projects focused on identifying and validating novel drug targets.
- Designing and executing complex experimental studies using state-of-the-art methodologies.
- Interpreting and analyzing large datasets, drawing scientifically sound conclusions.
- Developing and optimizing assays for target engagement and drug efficacy screening.
- Collaborating with medicinal chemists and other R&D teams to advance drug candidates.
- Mentoring and guiding junior scientists, fostering scientific growth and development.
- Staying abreast of the latest advancements in relevant scientific fields and technologies.
- Contributing to intellectual property generation through patents and publications.
- Presenting research findings at internal meetings and external scientific conferences.
- Playing a key role in shaping the strategic direction of the drug discovery portfolio.
The ideal candidate will possess a Ph.D. in Pharmacology, Biochemistry, Molecular Biology, Medicinal Chemistry, or a related discipline, with a strong publication record and a minimum of 8-10 years of post-doctoral research experience in drug discovery within the pharmaceutical or biotechnology industry. Proven expertise in a specific therapeutic area and a deep understanding of drug discovery processes, from target identification to lead optimization, are essential. Exceptional critical thinking, problem-solving skills, and proficiency in advanced experimental techniques are required. Excellent written and verbal communication skills are paramount for effective collaboration and knowledge sharing in a remote environment. The ability to lead, inspire, and manage research teams is crucial. Experience with bioinformatics and computational biology tools is highly desirable. This is a senior role for a driven scientist looking to make a significant impact remotely.
Senior Medicinal Chemist - Drug Discovery
Posted 2 days ago
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Key Responsibilities:
- Design novel small molecule drug candidates based on biological targets and SAR data.
- Plan and execute complex synthetic routes for the preparation of target compounds.
- Optimize synthetic methodologies to improve yield, purity, and scalability.
- Characterize synthesized compounds using advanced analytical techniques (e.g., NMR, LC-MS, HPLC).
- Evaluate the biological activity and pharmacokinetic properties of synthesized molecules.
- Collaborate effectively with biologists, pharmacologists, and computational chemists.
- Analyze and interpret experimental data to guide iterative design cycles.
- Troubleshoot synthetic challenges and develop innovative solutions.
- Maintain detailed and accurate laboratory notebooks and research reports.
- Stay current with the latest advancements in medicinal chemistry and drug discovery.
- Present research findings at internal project meetings and scientific conferences.
- Contribute to patent applications and scientific publications.
- PhD in Organic Chemistry or Medicinal Chemistry.
- Minimum of 5 years of post-doctoral or industry experience in drug discovery.
- Demonstrated expertise in synthetic organic chemistry and medicinal chemistry principles.
- Proven ability to design and synthesize novel small molecules with desired biological activities.
- Strong understanding of SAR and SPR for lead optimization.
- Proficiency with spectroscopic and chromatographic analytical techniques.
- Experience with computational chemistry software (e.g., Schrodinger, ChemDraw) is a plus.
- Excellent problem-solving, critical thinking, and experimental design skills.
- Strong written and verbal communication abilities, suitable for a remote scientific environment.
- Ability to work independently and as part of a collaborative, distributed team.
Senior Pharmaceutical Research Scientist - Drug Discovery
Posted 1 day ago
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Key responsibilities include designing and executing complex biological assays, performing medicinal chemistry synthesis, and utilizing cutting-edge analytical techniques to characterize potential drug candidates. You will collaborate closely with cross-functional teams, including biologists, pharmacologists, and clinical development specialists, to ensure seamless progression of research programs. The ideal candidate will possess a Ph.D. in Organic Chemistry, Medicinal Chemistry, Pharmacology, or a related discipline, with a strong publication record and a proven track record in small molecule drug discovery. Excellent problem-solving skills, a meticulous approach to experimental design, and strong written and verbal communication abilities are essential. Experience with computational chemistry tools and structure-based drug design is highly desirable. This is an exceptional opportunity for a talented scientist to contribute to the development of life-changing medicines.
Responsibilities:
- Lead research projects focused on the discovery and development of novel therapeutic agents.
- Design, synthesize, and characterize small molecule drug candidates.
- Develop and optimize biological assays for target validation and compound screening.
- Perform in vitro and in vivo studies to evaluate drug efficacy and pharmacokinetics.
- Collaborate with biologists, pharmacologists, and chemists to advance drug discovery programs.
- Analyze and interpret experimental data, and present findings to internal stakeholders and at scientific conferences.
- Contribute to the development of scientific strategy and identify new research opportunities.
- Maintain detailed laboratory notebooks and prepare research reports.
- Ensure compliance with all safety regulations and laboratory procedures.
- Mentor junior scientists and contribute to team development.
Qualifications:
- Ph.D. in Organic Chemistry, Medicinal Chemistry, Pharmacology, or a related field.
- Minimum of 5 years of post-doctoral or industry experience in pharmaceutical drug discovery.
- Proven track record in small molecule drug discovery, with a focus on medicinal chemistry.
- Extensive experience with synthetic organic chemistry techniques and structure elucidation (NMR, Mass Spectrometry).
- Proficiency in designing and performing a variety of biological assays.
- Familiarity with DMPK, toxicology, and preclinical development processes.
- Strong understanding of drug discovery principles and modern medicinal chemistry approaches.
- Excellent analytical, problem-solving, and critical thinking skills.
- Strong written and verbal communication skills, with a record of scientific publications.
- Ability to work effectively in a hybrid remote and lab-based environment.
Senior Pharmaceutical Research Scientist (Drug Discovery)
Posted 1 day ago
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Location: London, England, UK
Principal Pharmaceutical Research Scientist (Drug Discovery)
Posted 2 days ago
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Remote Pharmaceutical Research Scientist
Posted today
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Job Description
Responsibilities:
- Design, optimise, and execute complex in vitro and in vivo experimental assays to evaluate drug candidates.
- Analyse and interpret experimental data, applying statistical methods and drawing meaningful conclusions.
- Contribute to the development of new drug discovery strategies and research programs.
- Maintain detailed laboratory notebooks and records of experimental procedures and results.
- Prepare scientific reports, presentations, and publications for internal and external dissemination.
- Collaborate effectively with a multidisciplinary team of scientists, chemists, and biologists.
- Stay up-to-date with the latest scientific literature and technological advancements in pharmaceutical research.
- Troubleshoot experimental issues and develop alternative approaches when necessary.
- Contribute to intellectual property generation through the identification of novel drug targets and lead compounds.
- Ensure compliance with all relevant regulatory guidelines and safety protocols.
- Present research findings at internal meetings and potentially at scientific conferences.
- Assist in the management of research supplies and reagents.
- PhD or a Master's degree in Pharmacology, Pharmaceutical Sciences, Biology, Biochemistry, or a closely related field.
- Minimum of 5 years of post-doctoral or industry research experience in drug discovery or a related area.
- Proven expertise in a specific area of pharmaceutical research (e.g., oncology, immunology, neuroscience).
- Extensive experience with a range of experimental techniques relevant to drug discovery.
- Strong understanding of molecular and cellular biology, pharmacology, and pharmacokinetics.
- Demonstrated ability to design, execute, and interpret complex experiments.
- Excellent data analysis, statistical interpretation, and report-writing skills.
- Strong written and verbal communication skills, essential for remote collaboration.
- Ability to work independently with minimal supervision and as part of a collaborative research team.
- Proficiency in relevant scientific software and databases.
- A proactive and curious mindset with a genuine passion for scientific discovery and a commitment to producing high-quality research.
Remote Senior Pharmaceutical Research Scientist
Posted today
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Job Description
- Lead and execute complex research projects focused on the discovery and development of novel pharmaceutical agents.
- Design and conduct experiments, analyze data, and interpret results to advance drug candidate pipelines.
- Develop and validate new assays and methodologies relevant to drug discovery and preclinical development.
- Stay abreast of the latest scientific literature, technological advancements, and therapeutic trends in the pharmaceutical industry.
- Collaborate effectively with internal cross-functional teams (e.g., chemistry, biology, toxicology) and external partners.
- Mentor and guide junior scientists, fostering a collaborative and innovative research environment.
- Prepare high-quality scientific reports, publications, and patent applications.
- Contribute to the strategic planning and direction of the R&D department's research initiatives.
- Ensure compliance with all relevant regulatory guidelines, laboratory safety standards, and ethical principles.
- Manage research budgets and resources efficiently to achieve project milestones.
- Present research findings at scientific conferences and internal meetings.
- Ph.D. in Pharmacology, Medicinal Chemistry, Biochemistry, Molecular Biology, or a closely related discipline.
- Extensive postdoctoral experience and a strong track record of publications in peer-reviewed journals and/or patents in the pharmaceutical industry.
- Proven experience in drug discovery and development, with a deep understanding of relevant therapeutic areas and mechanisms of action.
- Expertise in designing, executing, and interpreting a range of experimental approaches relevant to pharmaceutical research.
- Strong analytical and problem-solving skills, with the ability to think critically and creatively.
- Excellent written and verbal communication skills, with the ability to clearly articulate complex scientific findings.
- Experience with relevant scientific software and data analysis tools.
- Demonstrated ability to lead research projects and work effectively within a collaborative team.
- Self-motivated with the ability to work independently and manage time effectively in a fully remote environment.
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Senior Pharmaceutical Research Scientist - Oncology
Posted today
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As a Senior Pharmaceutical Research Scientist, you will be instrumental in driving forward novel therapeutic strategies for cancer treatment. Your primary responsibilities will include designing and executing complex experiments, analyzing vast datasets, and contributing to the development of pre-clinical and clinical candidates. You will work collaboratively with cross-functional teams, including medicinal chemists, biologists, pharmacologists, and clinical development professionals, to advance projects from early discovery through to IND filing.
Key Responsibilities:
- Lead the design, execution, and interpretation of in vitro and in vivo experiments to assess the efficacy and safety of novel oncology drug candidates.
- Develop and validate assays for target engagement, mechanism of action, and drug response.
- Analyze and interpret complex biological and pharmacological data using statistical software and bioinformatics tools.
- Stay abreast of the latest scientific literature and technological advancements in oncology drug discovery.
- Contribute to the preparation of scientific publications, patents, and regulatory submissions.
- Mentor junior scientists and contribute to a positive and collaborative research environment.
- Effectively communicate research findings to internal stakeholders and at external scientific conferences.
- Manage project timelines and resources effectively to meet research milestones.
- Ensure all research activities are conducted in compliance with ethical standards and company policies.
- Ph.D. in Molecular Biology, Pharmacology, Immunology, or a related life science discipline.
- Minimum of 5-7 years of post-doctoral or industry experience in oncology drug discovery.
- Proven track record in designing and implementing complex biological assays.
- Strong understanding of cancer biology, immunology, and relevant signaling pathways.
- Proficiency in data analysis and statistical interpretation.
- Excellent written and verbal communication skills, with experience in preparing scientific reports and presentations.
- Demonstrated ability to work independently and as part of a collaborative team in a remote setting.
- Experience with preclinical models of cancer is highly desirable.
Principal Pharmaceutical Research Scientist (Remote)
Posted 1 day ago
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Job Description
Key Responsibilities:
- Lead the design and execution of pharmaceutical research projects.
- Identify and validate novel therapeutic targets.
- Design and synthesize potential drug candidates.
- Oversee preclinical development and characterization of lead compounds.
- Analyze and interpret complex biological and chemical data.
- Contribute to patent filings and scientific publications.
- Present research findings to internal and external stakeholders.
- Collaborate with cross-functional teams and external partners.
- Mentor junior scientists and foster scientific excellence.
- Stay abreast of cutting-edge research and technologies in drug discovery.
Qualifications:
- Ph.D. in Pharmacology, Medicinal Chemistry, Biochemistry, or a related life science discipline.
- 10+ years of relevant experience in pharmaceutical R&D.
- Proven track record in drug discovery and development.
- Expertise in one or more therapeutic areas or modalities.
- Strong understanding of molecular biology, biochemistry, and pharmacology.
- Experience with modern drug discovery techniques.
- Excellent analytical, problem-solving, and critical thinking skills.
- Exceptional communication, leadership, and presentation skills.
- Demonstrated ability to publish in high-impact journals.
Principal Pharmaceutical Research Scientist (Remote)
Posted 1 day ago
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Job Description
Key Responsibilities:
- Lead and conduct cutting-edge research in drug discovery and development.
- Design, execute, and interpret complex experiments to identify and validate novel drug targets and candidates.
- Develop and implement innovative scientific methodologies and assays.
- Provide scientific leadership and mentorship to research teams.
- Critically analyze data, draw sound conclusions, and make informed recommendations.
- Author high-quality scientific publications, patents, and regulatory documents.
- Collaborate effectively with internal and external stakeholders, including CROs and academic collaborators.
- Stay abreast of the latest scientific advancements and therapeutic trends in relevant disease areas.
- Contribute to the strategic planning and direction of the R&D pipeline.
Qualifications:
- PhD in Pharmacology, Medicinal Chemistry, Biochemistry, or a related life science discipline.
- Minimum of 8-10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
- Proven track record of scientific innovation and leadership, with significant contributions to drug discovery programs.
- Extensive experience in experimental design, data analysis, and interpretation.
- Strong publication record and/or patent portfolio.
- Excellent understanding of DMPK, toxicology, and early clinical development principles.
- Proficiency with relevant scientific software and instrumentation.
- Exceptional communication, presentation, and interpersonal skills.
- Ability to work independently and drive projects forward in a remote setting.