Principal Medicinal Chemist - London

W1A 0AX London, London £70000 Annually WhatJobs

Posted 16 days ago

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Job Description

full-time
Our client, a globally recognized pharmaceutical company, is seeking a highly experienced and innovative Principal Medicinal Chemist to join their drug discovery team in London, England, UK . This senior role requires a deep understanding of synthetic organic chemistry, drug design principles, and a proven track record of contributing to the discovery of novel therapeutics. You will lead complex research projects, mentor junior scientists, and drive the development of new chemical entities from early discovery through to pre-clinical development.

Responsibilities:
  • Design, synthesize, and optimize novel small molecules with therapeutic potential.
  • Lead and manage medicinal chemistry projects, setting clear objectives and timelines.
  • Utilize structure-activity relationship (SAR) and structure-property relationship (SPR) studies to guide compound optimization.
  • Collaborate effectively with biologists, pharmacologists, and other drug discovery disciplines.
  • Develop and implement innovative synthetic strategies for complex target molecules.
  • Analyze and interpret biological and chemical data to make informed decisions about compound progression.
  • Stay current with the latest literature, technologies, and trends in medicinal chemistry and drug discovery.
  • Supervise and mentor junior medicinal chemists, fostering their scientific and professional development.
  • Prepare scientific reports, presentations, and publications.
  • Contribute to the intellectual property strategy of the company through patent filings.
Qualifications:
  • PhD in Organic Chemistry, Medicinal Chemistry, or a closely related field.
  • Minimum of 8 years of experience in medicinal chemistry within the pharmaceutical or biotech industry.
  • Extensive experience in synthetic organic chemistry and modern drug discovery techniques.
  • Proven track record of successfully contributing to the discovery and development of small molecule therapeutics.
  • In-depth knowledge of SAR/SPR analysis and computational chemistry tools.
  • Strong understanding of ADME/Tox principles and their impact on drug discovery.
  • Excellent problem-solving, critical thinking, and decision-making skills.
  • Strong leadership, mentoring, and interpersonal skills.
  • Excellent written and verbal communication skills, with a publication record.
  • Experience with patent drafting is a plus.
This is a pivotal role for a passionate and driven medicinal chemist seeking to make a significant impact on the future of medicine. The position is located in London, England, UK .
Location: London, England, UK
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Research Chemist

City of Westminster, London DataAnnotation

Posted today

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Job Description

We are looking for a research scientist to join our team to train AI models. You will measure the progress of these AI chatbots, evaluate their logic, and solve problems to improve the quality of each model.

In this role you will need to hold an expert understanding of chemistry- a completed or in progress Masters/PhD is preferred but not required. Other related fields include, but are not limited to: Research and Development Chemist, Formulation Scientist, Development Chemist, Analytical Chemist, Chemical Engineer, Medicinal Chemist, Biochemist, Process Development Chemist.

Benefits:

  • This is a full-time or part-time REMOTE position
  • You’ll be able to choose which projects you want to work on
  • You can work on your own schedule
  • Projects are paid hourly starting at $40+ per hour, with bonuses on high-quality and high-volume work

Responsibilities:

  • Give AI chatbots diverse and complex chemistry problems and evaluate their outputs
  • Evaluate the quality produced by AI models for correctness and performance

Qualifications:

  • A current, in progress, or completed Masters and/or PhD is preferred but not required
  • Fluency in English (native or bilingual level)
  • Detail-oriented
  • Proficient in chemistry, inductive/deductive reasoning, physical/temporal/ spatial reasoning

Note: Payment is made via PayPal. We will never ask for any money from you. PayPal will handle any currency conversions from USD. This job is only available to those in the US, UK, Canada, Australia, or New Zealand. Those located outside of these countries will not see work or assessments available on our site at this time.

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Research Chemist

London, London DataAnnotation

Posted today

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Job Description

Job Description

We are looking for a research scientist to join our team to train AI models. You will measure the progress of these AI chatbots, evaluate their logic, and solve problems to improve the quality of each model.

In this role you will need to hold an expert understanding of chemistry- a completed or in progress Masters/PhD is preferred but not required. Other related fields include, but are not limited to: Research and Development Chemist, Formulation Scientist, Development Chemist, Analytical Chemist, Chemical Engineer, Medicinal Chemist, Biochemist, Process Development Chemist.

Benefits:

  • This is a full-time or part-time REMOTE position
  • You’ll be able to choose which projects you want to work on
  • You can work on your own schedule
  • Projects are paid hourly starting at $40+ per hour, with bonuses on high-quality and high-volume work

Responsibilities:

  • Give AI chatbots diverse and complex chemistry problems and evaluate their outputs
  • Evaluate the quality produced by AI models for correctness and performance

Qualifications:

  • A current, in progress, or completed Masters and/or PhD is preferred but not required
  • Fluency in English (native or bilingual level)
  • Detail-oriented
  • Proficient in chemistry, inductive/deductive reasoning, physical/temporal/ spatial reasoning

Note: Payment is made via PayPal. We will never ask for any money from you. PayPal will handle any currency conversions from USD. This job is only available to those in the US, UK, Canada, Australia, or New Zealand. Those located outside of these countries will not see work or assessments available on our site at this time.

This advertiser has chosen not to accept applicants from your region.

Principal Research Chemist - Pharmaceutical Development

WC1A 0AX London, London £80000 Annually WhatJobs

Posted 18 days ago

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full-time
Our client, a leading pharmaceutical innovator, is seeking a highly accomplished Principal Research Chemist to join their advanced pharmaceutical development team in London, England, UK . This role offers a hybrid working model, combining hands-on laboratory work with strategic research planning and remote analysis. You will be instrumental in leading the development of novel chemical entities, optimizing synthesis processes, and contributing to the advancement of drug candidates from discovery through to clinical trials. This position requires exceptional scientific expertise, a deep understanding of organic and medicinal chemistry, and proven leadership capabilities in a research environment.

Key Responsibilities:
  • Lead the design, synthesis, and optimization of complex organic molecules for pharmaceutical applications.
  • Develop innovative and scalable synthetic routes, addressing challenges in process chemistry.
  • Direct research efforts in medicinal chemistry to identify and improve lead compounds.
  • Utilize advanced analytical techniques (e.g., NMR, MS, X-ray crystallography) for structural elucidation and purity assessment.
  • Collaborate with cross-functional teams, including biologists, toxicologists, and formulation scientists, to advance drug candidates.
  • Oversee and mentor junior research chemists, guiding their technical development and project execution.
  • Develop and implement robust quality control measures for chemical synthesis and intermediates.
  • Contribute to intellectual property generation through patent filings and scientific publications.
  • Stay abreast of cutting-edge research, emerging technologies, and industry best practices in organic and medicinal chemistry.
  • Prepare detailed scientific reports, presentations, and regulatory documentation.
  • Ensure compliance with all laboratory safety regulations and ethical guidelines.
  • Manage research project timelines, resources, and budgets effectively.
Qualifications:
  • Ph.D. in Organic Chemistry, Medicinal Chemistry, or a closely related field.
  • Minimum of 8 years of relevant industrial experience in pharmaceutical research and development.
  • Demonstrated track record of successfully leading complex synthetic chemistry projects.
  • Extensive experience in modern synthetic methodologies, reaction optimization, and process development.
  • Expertise in analytical characterization techniques for organic compounds.
  • Strong understanding of drug discovery principles, pharmacokinetics, and toxicology.
  • Proven ability to interpret complex data and provide strategic insights.
  • Excellent leadership, communication, and interpersonal skills.
  • Experience with computational chemistry and molecular modeling is advantageous.
  • Ability to thrive in a collaborative, fast-paced, hybrid research environment.
This is a senior-level opportunity for a highly skilled and motivated chemist to make a significant contribution to the development of next-generation pharmaceuticals. Join a world-class organization dedicated to scientific excellence and innovation.
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Lead Process Chemist - Pharmaceutical Manufacturing

SW1A 0AA London, London £70000 Annually WhatJobs

Posted 19 days ago

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full-time
Our client, a globally recognized pharmaceutical company, is seeking an experienced Lead Process Chemist to join their innovative research and development division in London, England, UK . This role operates on a hybrid model, offering a flexible work arrangement. The Lead Process Chemist will be responsible for the development, optimization, and scale-up of chemical processes for novel drug substances. You will play a crucial role in translating laboratory-scale synthesis into robust, efficient, and safe manufacturing processes. Key duties include designing and executing experiments, performing process hazard analyses, troubleshooting manufacturing issues, and ensuring compliance with GMP regulations. The ideal candidate will possess a strong background in organic chemistry, process chemistry, and chemical engineering principles. Experience with analytical techniques (HPLC, GC, MS) and process analytical technology (PAT) is essential. You should have a proven ability to lead projects, mentor junior chemists, and collaborate effectively with cross-functional teams including manufacturing, quality assurance, and regulatory affairs. Strong problem-solving skills, attention to detail, and excellent documentation practices are required. This position offers an exciting opportunity to contribute to the development of life-saving medicines and advance your career within a leading pharmaceutical organization. We are looking for a strategic thinker with a passion for chemical process innovation and a commitment to scientific excellence.
Key Responsibilities:
  • Lead the development and optimization of chemical synthesis processes.
  • Scale-up processes from laboratory to pilot plant and commercial manufacturing.
  • Perform process hazard assessments (PHA) and safety reviews.
  • Troubleshoot and resolve process-related issues during manufacturing campaigns.
  • Ensure all processes comply with Good Manufacturing Practices (GMP) and regulatory guidelines.
  • Develop and validate analytical methods for process monitoring.
  • Write comprehensive process development reports and documentation.
  • Mentor and provide technical guidance to junior chemists and technicians.
  • Collaborate with manufacturing, QA, and regulatory affairs teams.
Qualifications:
  • Ph.D. or Master's degree in Organic Chemistry, Process Chemistry, Chemical Engineering, or a related field.
  • 5-7 years of experience in pharmaceutical process development.
  • Strong knowledge of synthetic organic chemistry and reaction mechanisms.
  • Expertise in process optimization, scale-up, and technology transfer.
  • Experience with GMP, ICH guidelines, and regulatory submissions.
  • Proficiency in analytical techniques (HPLC, GC, MS, NMR).
  • Excellent leadership, communication, and interpersonal skills.
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