Explore opportunities in the field of medicinal chemistry. Medicinal chemists are vital in the pharmaceutical industry, focusing on designing, synthesizing, and testing new drug candidates. They apply their knowledge of chemistry, biology, and pharmacology to create innovative therapies for various diseases. Job roles often involve 88 Medicinal Chemist jobs in the United Kingdom
Principal Medicinal Chemist
CB2 1AA Cambridge, Eastern
£70000 Annually
WhatJobs
Posted 1 day ago
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Job Description
Our client, a globally recognized pharmaceutical company at the forefront of drug discovery, is seeking a highly motivated and experienced Principal Medicinal Chemist to join their state-of-the-art research facilities in Cambridge, Cambridgeshire, UK . This pivotal role involves leading cutting-edge research programs focused on the design and synthesis of novel small molecules for therapeutic intervention. You will be responsible for driving projects from hit identification through to lead optimization, working collaboratively within multidisciplinary teams to advance promising drug candidates towards clinical development.
The ideal candidate will possess a Ph.D. in Organic Chemistry or Medicinal Chemistry, coupled with a minimum of 8 years of post-doctoral experience in the pharmaceutical industry. You should have a demonstrated track record of successfully designing and synthesizing complex organic molecules, with a strong understanding of structure-activity relationships (SAR), ADMET properties, and drug design principles. Exceptional synthetic organic chemistry skills, proficiency in modern analytical techniques, and a deep knowledge of medicinal chemistry are essential. You will be expected to lead and mentor junior chemists, manage project timelines, and contribute to the strategic direction of our drug discovery efforts. A passion for scientific innovation and a commitment to ethical research practices are paramount.
Key Responsibilities:
Required Qualifications:
The ideal candidate will possess a Ph.D. in Organic Chemistry or Medicinal Chemistry, coupled with a minimum of 8 years of post-doctoral experience in the pharmaceutical industry. You should have a demonstrated track record of successfully designing and synthesizing complex organic molecules, with a strong understanding of structure-activity relationships (SAR), ADMET properties, and drug design principles. Exceptional synthetic organic chemistry skills, proficiency in modern analytical techniques, and a deep knowledge of medicinal chemistry are essential. You will be expected to lead and mentor junior chemists, manage project timelines, and contribute to the strategic direction of our drug discovery efforts. A passion for scientific innovation and a commitment to ethical research practices are paramount.
Key Responsibilities:
- Lead medicinal chemistry programs to identify and optimize novel drug candidates.
- Design and synthesize complex organic molecules utilizing a variety of synthetic methodologies.
- Interpret SAR data and guide synthetic strategies to improve potency, selectivity, and pharmacokinetic profiles.
- Collaborate closely with biologists, pharmacologists, and DMPK scientists to assess compound performance.
- Develop and implement efficient and scalable synthetic routes.
- Stay current with the latest advancements in medicinal chemistry, synthetic methodology, and drug discovery technologies.
- Troubleshoot synthetic challenges and devise creative solutions.
- Manage external collaborations and contract research organizations (CROs) as needed.
- Mentor and provide guidance to junior medicinal chemists.
- Contribute to intellectual property generation through patent applications.
Required Qualifications:
- Ph.D. in Organic or Medicinal Chemistry.
- 8+ years of relevant industry experience in medicinal chemistry.
- Proven expertise in modern synthetic organic chemistry techniques.
- Strong understanding of drug discovery principles, including SAR, ADMET, and PK/PD.
- Experience with relevant analytical techniques (NMR, MS, HPLC).
- Demonstrated ability to lead projects and mentor team members.
- Excellent written and verbal communication skills.
- Track record of successful drug candidate progression.
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Principal Medicinal Chemist
CB2 0AX Cambridge, Eastern
£70000 Annually
WhatJobs
Posted 1 day ago
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Job Description
Our client, a leading pharmaceutical research and development company, is seeking an exceptional Principal Medicinal Chemist to drive drug discovery programs. This is a vital, fully remote position, allowing you to contribute to groundbreaking research from your UK-based location. You will be responsible for the design, synthesis, and optimisation of novel small molecules with therapeutic potential. This involves leveraging your extensive knowledge of organic synthesis, structure-activity relationships (SAR), and drug metabolism and pharmacokinetic (DMPK) principles to advance lead compounds through the discovery pipeline. The ideal candidate will possess a PhD in Medicinal Chemistry, Organic Chemistry, or a related field, with a significant track record of success in drug discovery. You should be proficient in modern synthetic techniques, computational chemistry tools, and various analytical methods (e.g., NMR, LC-MS). This remote role requires strong leadership qualities, excellent problem-solving skills, and the ability to collaborate effectively with biologists, pharmacologists, and other scientists across multidisciplinary teams. You will mentor junior chemists, contribute to strategic research planning, and present findings to internal stakeholders and external collaborators. A deep understanding of disease biology and target validation is essential. Your contributions will be crucial in identifying and developing innovative therapies for unmet medical needs. You must be adept at working independently, managing complex synthetic projects, and communicating scientific results clearly and concisely in a remote setting. Experience in hit-to-lead and lead optimisation campaigns is highly valued. This is a unique opportunity to shape the future of drug discovery within a dynamic and research-intensive environment.
Responsibilities:
Qualifications:
Responsibilities:
- Design, synthesize, and characterize novel small molecule drug candidates.
- Develop and optimize synthetic routes for complex molecules.
- Conduct Structure-Activity Relationship (SAR) studies.
- Collaborate with biologists to integrate biological data into compound design.
- Apply knowledge of DMPK and ADME properties to optimize compounds.
- Utilize computational chemistry tools for molecular design and analysis.
- Troubleshoot synthetic challenges and guide junior chemists.
- Contribute to project strategy and intellectual property generation.
- Prepare technical reports and present research findings.
- Maintain a high level of scientific rigor and innovation.
Qualifications:
- PhD in Medicinal Chemistry, Organic Chemistry, or a related field.
- Extensive experience in synthetic organic chemistry and medicinal chemistry.
- Proven track record in drug discovery, with contributions to advancing candidates.
- Strong understanding of SAR, DMPK, and ADME principles.
- Proficiency with modern synthetic methodologies and purification techniques.
- Experience with analytical techniques (NMR, LC-MS, HPLC).
- Familiarity with computational chemistry software.
- Excellent problem-solving, critical thinking, and communication skills.
- Ability to lead research efforts and mentor junior staff remotely.
- Strong collaborative spirit and ability to work effectively in cross-functional teams.
This advertiser has chosen not to accept applicants from your region.
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Principal Medicinal Chemist
M1 1AE Manchester, North West
£80000 Annually
WhatJobs
Posted 1 day ago
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Job Description
Our client, a groundbreaking pharmaceutical research company at the forefront of drug discovery, is seeking a highly experienced Principal Medicinal Chemist to join their innovative team. This role, which is fully remote, offers the unique opportunity to contribute significantly to the development of novel therapeutics that address unmet medical needs. You will be responsible for the design, synthesis, and optimisation of small molecules with potential therapeutic activity, working collaboratively with biologists, pharmacologists, and computational chemists. Key responsibilities include leading drug discovery projects from hit identification through to lead optimisation, applying expertise in synthetic organic chemistry, structure-activity relationships (SAR), and ADMET profiling. You will be expected to contribute to project strategy, mentor junior chemists, and present research findings at internal and external forums. The ideal candidate will possess a PhD in Organic or Medicinal Chemistry, with a minimum of 8-10 years of post-doctoral experience in the pharmaceutical industry. A deep understanding of drug discovery processes, modern synthetic methodologies, and analytical techniques (NMR, MS, HPLC) is essential. Proven experience in leading projects and a strong publication record in peer-reviewed journals are highly desirable. You must possess excellent problem-solving abilities, strong communication skills, and the capacity to work independently and effectively in a virtual environment. This remote position requires a proactive and self-driven individual with a passion for scientific innovation and a commitment to improving patient outcomes through cutting-edge pharmaceutical research.
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2
Principal Medicinal Chemist
BS1 6XS Bristol, South West
£70000 Annually
WhatJobs
Posted 3 days ago
Job Viewed
Job Description
Our client is seeking a highly accomplished and innovative Principal Medicinal Chemist to join their cutting-edge pharmaceutical research team. This is a fully remote position, offering the unique opportunity to contribute significantly to drug discovery from anywhere within the UK. You will play a pivotal role in designing, synthesising, and optimising novel small molecules with therapeutic potential. The ideal candidate will possess a deep understanding of structure-activity relationships (SAR), drug metabolism, and pharmacokinetic (DMPK) properties, along with extensive experience in synthetic organic chemistry. You will lead complex research projects, guiding synthetic strategies, and interpreting experimental data to drive project progression. Key responsibilities include collaborating closely with biologists, pharmacologists, and other scientists to define target profiles and design molecules that meet stringent efficacy and safety criteria. You will be expected to contribute innovative ideas, identify new chemical matter, and solve challenging synthetic problems. Experience in managing external collaborations with contract research organisations (CROs) and a strong publication record in peer-reviewed journals are highly desirable. This role requires a strategic thinker with exceptional problem-solving skills, meticulous attention to detail, and the ability to independently manage multiple research objectives. A proven track record of successful drug discovery contributions, demonstrated through lead optimization or candidate selection, is essential. We are looking for a scientifically rigorous individual with excellent communication and leadership skills, capable of driving scientific innovation in a remote environment. If you are a passionate medicinal chemist eager to make a substantial impact on the development of new medicines, we encourage you to apply.
Responsibilities:
Responsibilities:
- Design, synthesise, and characterise novel small molecules for drug discovery programs.
- Develop and execute synthetic routes for complex target molecules.
- Conduct structure-activity relationship (SAR) studies to optimise potency and selectivity.
- Collaborate with biologists and pharmacologists to define project goals.
- Evaluate DMPK properties and metabolic stability of drug candidates.
- Troubleshoot challenging synthetic chemistry problems.
- Independently manage multiple research projects and priorities.
- Contribute to intellectual property generation and patent applications.
- Stay abreast of the latest advances in medicinal chemistry and drug discovery.
- Mentor junior chemists and contribute to team scientific discussions.
- PhD in Medicinal Chemistry, Organic Chemistry, or a related field.
- Extensive experience in medicinal chemistry with a focus on drug discovery.
- Proven track record of contributions to successful drug discovery projects.
- Expertise in synthetic organic chemistry and modern analytical techniques.
- Strong understanding of SAR, DMPK, and pharmacology principles.
- Excellent problem-solving and critical thinking skills.
- Ability to work independently and manage projects in a remote setting.
- Strong written and verbal communication skills.
- Experience with computational chemistry tools is a plus.
This advertiser has chosen not to accept applicants from your region.
3
Lead Medicinal Chemist
BN1 1YS East Sussex, South East
£70000 Annually
WhatJobs
Posted 3 days ago
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Job Description
Our client, a cutting-edge pharmaceutical research and development company, is seeking a highly skilled and innovative Lead Medicinal Chemist to join their dynamic scientific team in Brighton, East Sussex, UK . This role will be crucial in driving the design and synthesis of novel small molecules for therapeutic applications, contributing to the discovery of life-saving medicines.
As the Lead Medicinal Chemist, you will be responsible for guiding and mentoring a team of synthetic chemists, managing research projects from conception to candidate selection, and contributing to the strategic direction of drug discovery programs. You will leverage your expertise in organic synthesis, structure-activity relationships (SAR), and modern drug discovery techniques to identify and optimize lead compounds. The ideal candidate will possess a strong publication record, a deep understanding of chemical biology, and the ability to foster a collaborative and results-oriented research environment.
Key Responsibilities:
Qualifications:
As the Lead Medicinal Chemist, you will be responsible for guiding and mentoring a team of synthetic chemists, managing research projects from conception to candidate selection, and contributing to the strategic direction of drug discovery programs. You will leverage your expertise in organic synthesis, structure-activity relationships (SAR), and modern drug discovery techniques to identify and optimize lead compounds. The ideal candidate will possess a strong publication record, a deep understanding of chemical biology, and the ability to foster a collaborative and results-oriented research environment.
Key Responsibilities:
- Lead and mentor a team of medicinal and synthetic chemists, fostering innovation and scientific excellence.
- Design and execute synthetic routes for novel small molecules with potential therapeutic applications.
- Develop and optimize SAR for lead compounds through iterative cycles of design, synthesis, and testing.
- Collaborate closely with biologists, pharmacologists, and DMPK scientists to advance drug discovery programs.
- Utilize computational chemistry tools and databases to guide molecular design and predict properties.
- Manage project timelines, resources, and budgets effectively.
- Stay abreast of the latest advancements in medicinal chemistry, synthetic methodology, and drug discovery technologies.
- Prepare scientific reports, presentations, and contribute to patent applications.
- Ensure safe laboratory practices and compliance with all relevant regulations.
- Contribute to the strategic planning of the drug discovery pipeline.
- Present research findings at internal and external scientific meetings.
Qualifications:
- PhD in Organic Chemistry, Medicinal Chemistry, or a closely related field.
- Minimum of 7-10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
- Demonstrated track record of successfully leading drug discovery projects and delivering preclinical candidates.
- Extensive experience in synthetic organic chemistry and a strong understanding of reaction mechanisms.
- Proficiency in SAR analysis and iterative optimization of small molecules.
- Familiarity with modern drug discovery platforms and technologies.
- Excellent problem-solving, analytical, and critical thinking skills.
- Strong leadership, project management, and team collaboration abilities.
- Excellent written and verbal communication skills, with a proven ability to present complex scientific data clearly.
- Experience with cheminformatics and molecular modeling software is desirable.
This advertiser has chosen not to accept applicants from your region.
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Principal Medicinal Chemist
SO14 0AA Southampton, South East
£75000 Annually
WhatJobs
Posted 3 days ago
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Job Description
A leading pharmaceutical research and development company in **Southampton, Hampshire** is seeking a highly skilled and innovative Principal Medicinal Chemist to contribute to groundbreaking drug discovery programs. This is a hybrid position, offering a dynamic work environment that combines on-site laboratory research with remote data analysis and collaboration. You will be responsible for designing, synthesizing, and optimizing novel small molecules with therapeutic potential, working at the forefront of medicinal chemistry. Your expertise will be crucial in driving lead identification and optimization campaigns, employing state-of-the-art techniques and a deep understanding of structure-activity relationships (SAR). Key duties include leading synthetic chemistry projects, interpreting complex biological and chemical data, contributing to strategic research planning, and mentoring junior chemists. The ideal candidate will possess a PhD in Organic or Medicinal Chemistry, with extensive post-doctoral or industry experience in drug discovery. A proven track record of successful compound design and synthesis, demonstrated by publications and patents, is essential. You should be proficient in modern synthetic methodologies, analytical techniques (NMR, LC-MS), and computational chemistry tools. Excellent problem-solving abilities, strong communication skills, and the capacity to work effectively both independently and as part of a multidisciplinary team are required. This role offers the opportunity to work on challenging projects, access cutting-edge technologies, and make a significant impact on the development of new medicines. We offer a competitive salary, comprehensive benefits package, and opportunities for career advancement within a world-class research organization. Your contribution will be vital in bringing innovative therapies to patients.
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5
Senior Medicinal Chemist
AB10 1BP Aberdeen, Scotland
£65000 Annually
WhatJobs
Posted 4 days ago
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Job Description
Our client, a pioneering pharmaceutical research organisation, is actively seeking a highly accomplished Senior Medicinal Chemist to join their cutting-edge drug discovery team. This is a fully remote position, offering an exceptional opportunity for an experienced chemist to contribute to the development of novel therapeutics from their home base. You will be instrumental in designing, synthesising, and optimising novel chemical entities with therapeutic potential, utilising advanced organic chemistry techniques and collaborating with biologists and pharmacologists. The ideal candidate will possess a deep understanding of structure-activity relationships (SAR), drug metabolism, and pharmacokinetic (DMPK) properties. This role requires a proactive, innovative mindset and strong collaborative skills for remote teamwork.
Responsibilities:
Responsibilities:
- Design and synthesise novel small molecules with desired pharmacological properties for therapeutic targets.
- Conduct literature searches and utilise cheminformatics tools to identify lead compounds and guide synthetic strategies.
- Optimise lead compounds to improve potency, selectivity, pharmacokinetic properties, and safety profiles.
- Plan and execute complex multi-step organic synthesis projects.
- Characterise synthesised compounds using a range of analytical techniques (e.g., NMR, MS, HPLC).
- Collaborate closely with biologists, pharmacologists, and DMPK scientists to design and interpret experimental results.
- Develop and implement innovative synthetic methodologies.
- Troubleshoot synthetic challenges and guide research associates in laboratory execution.
- Maintain accurate and detailed laboratory notebooks and research reports.
- Present research findings at internal meetings and potentially external conferences.
- Contribute to intellectual property generation and patent filings.
- Stay abreast of the latest advancements in medicinal chemistry and drug discovery.
- Ph.D. in Medicinal Chemistry, Organic Chemistry, or a closely related field.
- Minimum of 5-7 years of post-doctoral and/or industry experience in drug discovery.
- Demonstrated expertise in modern synthetic organic chemistry and a strong track record of synthesising complex molecules.
- In-depth knowledge of structure-activity relationship (SAR) analysis and medicinal chemistry principles.
- Familiarity with drug metabolism, pharmacokinetics (DMPK), and toxicology considerations.
- Proficiency in analytical techniques for compound characterisation (NMR, MS, HPLC, etc.).
- Excellent problem-solving, critical thinking, and scientific reasoning skills.
- Strong communication and interpersonal skills, with the ability to collaborate effectively in a remote team environment.
- Experience with computational chemistry tools and databases is a plus.
- Proven ability to manage research projects independently and deliver results.
This advertiser has chosen not to accept applicants from your region.
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Principal Medicinal Chemist
CF10 1AA Cardiff, Wales
£75000 Annually
WhatJobs
Posted 7 days ago
Job Viewed
Job Description
Our client is a pioneering biopharmaceutical company at the forefront of developing novel therapeutics for challenging diseases. We are seeking an exceptional Principal Medicinal Chemist to join our innovative research team in Cardiff, Wales, UK . This role is fully remote, allowing you to contribute to cutting-edge drug discovery from anywhere. You will be responsible for the design, synthesis, and optimization of small molecule drug candidates, playing a critical role in advancing our pipeline from discovery through to preclinical development. Your expertise in synthetic organic chemistry, structure-activity relationships (SAR), and drug design will be instrumental in identifying and developing transformational medicines.
Responsibilities:
Responsibilities:
- Lead the design and synthesis of novel small molecule compounds with desired biological activity and pharmacokinetic properties.
- Develop and execute creative synthetic routes to complex target molecules.
- Conduct detailed SAR studies to optimize lead compounds, improving potency, selectivity, and ADMET profiles.
- Collaborate closely with biologists, pharmacologists, and other research scientists to define target product profiles and guide compound selection.
- Utilize computational chemistry tools and techniques to aid in rational drug design.
- Manage external synthesis projects and CRO relationships to augment internal capabilities.
- Troubleshoot challenging synthetic chemistry problems and identify innovative solutions.
- Ensure all research activities are conducted to the highest scientific standards and are well-documented in electronic lab notebooks.
- Contribute to the strategic direction of drug discovery programs and identify new therapeutic opportunities.
- Prepare and present research findings at internal meetings and scientific conferences.
- Contribute to patent applications and scientific publications.
- Mentor and guide junior chemists within the research team, fostering a culture of scientific excellence.
- Stay abreast of the latest advancements in medicinal chemistry, synthetic methodology, and drug discovery technologies.
- Ensure compliance with all relevant health, safety, and environmental regulations.
- Ph.D. in Medicinal Chemistry, Organic Chemistry, or a closely related field.
- Minimum of 8 years of post-doctoral experience in medicinal chemistry within the pharmaceutical or biotechnology industry.
- Proven track record of success in designing and synthesizing novel small molecules that have progressed into drug development.
- Extensive experience in modern synthetic organic chemistry, including asymmetric synthesis and multi-step synthesis.
- Deep understanding of SAR, pharmacokinetics (PK), and absorption, distribution, metabolism, excretion, and toxicity (ADMET) principles.
- Proficiency with computational chemistry software and molecular modeling techniques.
- Excellent analytical and problem-solving skills, with a rigorous scientific approach.
- Exceptional written and verbal communication skills, with the ability to clearly present complex scientific data.
- Demonstrated leadership capabilities and experience mentoring junior scientists.
- Ability to work independently and collaboratively in a fast-paced, remote research environment.
- Strong publication record and experience with intellectual property (patents) is highly desirable.
This advertiser has chosen not to accept applicants from your region.
7
Principal Medicinal Chemist
L1 8JQ Liverpool, North West
£65000 Annually
WhatJobs
Posted 7 days ago
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Job Description
Our client, a leading pharmaceutical company dedicated to discovering and developing life-saving medicines, is seeking a highly experienced Principal Medicinal Chemist to join their esteemed research and development team in Liverpool, Merseyside, UK . This critical role offers the opportunity to lead innovative drug discovery programs, contributing significantly to the advancement of novel therapeutics. You will be at the forefront of designing, synthesizing, and optimizing small molecules with the potential to become groundbreaking new medicines.
The ideal candidate will possess a profound understanding of organic synthesis, medicinal chemistry principles, and structure-activity relationships (SAR). You will be responsible for guiding synthetic strategy, troubleshooting complex synthetic challenges, and contributing to the preclinical development of drug candidates. Collaboration with biologists, pharmacologists, and other research scientists is essential to drive projects from early discovery through to candidate selection. A strong publication record, patent filings, and a passion for drug discovery are highly valued. This position demands exceptional scientific acumen, leadership capabilities, and a commitment to excellence in pharmaceutical research.
Key Responsibilities:
Required Qualifications:
This is an outstanding opportunity to contribute to innovative drug discovery in a highly collaborative and scientifically rich environment. Join a team that is committed to making a difference in patient lives.
The ideal candidate will possess a profound understanding of organic synthesis, medicinal chemistry principles, and structure-activity relationships (SAR). You will be responsible for guiding synthetic strategy, troubleshooting complex synthetic challenges, and contributing to the preclinical development of drug candidates. Collaboration with biologists, pharmacologists, and other research scientists is essential to drive projects from early discovery through to candidate selection. A strong publication record, patent filings, and a passion for drug discovery are highly valued. This position demands exceptional scientific acumen, leadership capabilities, and a commitment to excellence in pharmaceutical research.
Key Responsibilities:
- Lead medicinal chemistry efforts for drug discovery programs, from hit identification to lead optimization.
- Design and synthesize novel small molecules with desired pharmacological profiles.
- Develop and implement robust synthetic routes for complex targets.
- Conduct structure-activity relationship (SAR) studies and guide chemical modifications.
- Collaborate with biologists and pharmacologists to assess compound efficacy and safety.
- Troubleshoot synthetic challenges and provide strategic guidance to project teams.
- Contribute to the selection and advancement of preclinical drug candidates.
- Mentor and train junior medicinal chemists and research associates.
- Prepare scientific reports, presentations, and contribute to patent applications.
- Stay current with the latest advancements in medicinal chemistry, synthetic methodologies, and drug discovery technologies.
Required Qualifications:
- Ph.D. in Organic Chemistry or Medicinal Chemistry from a reputable institution.
- A minimum of 7 years of experience in medicinal chemistry within the pharmaceutical or biotechnology industry.
- Proven track record of successfully contributing to the discovery and development of drug candidates.
- Extensive experience in synthetic organic chemistry, including complex multi-step synthesis.
- Deep understanding of SAR principles and computational chemistry tools.
- Familiarity with assay development and biological evaluation of compounds.
- Excellent analytical, problem-solving, and critical thinking skills.
- Strong written and verbal communication skills, with the ability to present complex scientific data effectively.
- Demonstrated leadership and project management capabilities.
- Experience with intellectual property and patent processes is a plus.
This is an outstanding opportunity to contribute to innovative drug discovery in a highly collaborative and scientifically rich environment. Join a team that is committed to making a difference in patient lives.
This advertiser has chosen not to accept applicants from your region.
8
Senior Medicinal Chemist
NR1 3 Norwich, Eastern
£60000 Annually
WhatJobs
Posted 8 days ago
Job Viewed
Job Description
Our client, a dynamic pharmaceutical company focused on novel therapeutics, is seeking a highly skilled Senior Medicinal Chemist to join their drug discovery team. This hybrid position, located in Norwich, Norfolk, UK , offers an exciting opportunity to contribute to the design and synthesis of innovative drug candidates. You will play a crucial role in lead optimization programs, working closely with biologists and pharmacologists to identify and develop new chemical entities with therapeutic potential. This role requires a strong background in synthetic organic chemistry, a deep understanding of drug discovery principles, and a passion for medicinal chemistry.
Key Responsibilities:
Key Responsibilities:
- Design and synthesize novel small molecules targeting key disease pathways.
- Plan and execute multi-step organic synthesis routes for lead compounds and analogs.
- Collaborate with biologists to define structure-activity relationships (SAR) and structure-property relationships (SPR).
- Optimize lead compounds for potency, selectivity, pharmacokinetic properties, and safety.
- Utilize computational chemistry tools and databases to guide compound design.
- Characterize synthesized compounds using analytical techniques (e.g., NMR, LC-MS, HPLC).
- Manage external synthesis collaborations and CROs.
- Contribute to the intellectual property portfolio through patent filings.
- Stay current with advances in medicinal chemistry, synthetic methodology, and drug discovery.
- Prepare high-quality reports, presentations, and publications.
- Ph.D. in Organic Chemistry or Medicinal Chemistry.
- Minimum of 5 years of post-doctoral experience in medicinal chemistry within the pharmaceutical or biotechnology industry.
- Demonstrated success in designing and synthesizing novel compounds for drug discovery programs.
- Expertise in synthetic organic chemistry, including reaction optimization and troubleshooting.
- Strong understanding of drug discovery principles, ADME/Tox considerations, and SAR analysis.
- Experience with common medicinal chemistry software and databases.
- Excellent analytical and problem-solving skills.
- Strong communication, teamwork, and presentation skills.
- Ability to work independently and manage multiple projects simultaneously.
- Publications in peer-reviewed journals and/or patent filings are desirable.
This advertiser has chosen not to accept applicants from your region.
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