6,892 Drug Discovery jobs in the United Kingdom

Research Scientist - Drug Discovery

BN1 1AA East Sussex, South East £45000 Annually WhatJobs

Posted 3 days ago

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full-time
A pioneering biotechnology company at the forefront of innovative therapeutic development is seeking a talented Research Scientist to join their dynamic Scientific Research & Development team. This role is pivotal in advancing our drug discovery programs, contributing to the identification and validation of novel drug targets. You will be involved in designing and executing complex experiments, analysing experimental data, and interpreting results to inform strategic decisions. Responsibilities include conducting literature reviews, developing new assays, troubleshooting experimental protocols, and maintaining detailed laboratory records. Collaboration with cross-functional teams, including medicinal chemists, biologists, and pharmacologists, will be essential. The ideal candidate will have a PhD or a Master's degree in a relevant scientific discipline (e.g., Molecular Biology, Biochemistry, Pharmacology) with a strong background in drug discovery methodologies. Proven experience in cell culture, molecular biology techniques, and biochemical assays is required. Familiarity with target validation, lead optimization, or specific therapeutic areas is a plus.

We are looking for a highly motivated, detail-oriented individual with excellent analytical and problem-solving skills. Strong written and verbal communication abilities are essential for presenting findings and contributing to scientific publications and reports. This role operates on a hybrid model, combining essential laboratory-based research in our state-of-the-art facilities in Brighton, East Sussex, UK with remote work for data analysis, literature review, and report writing. You must be adept at working independently and as part of a collaborative team. A passion for scientific innovation and a commitment to advancing human health are key. This is an exceptional opportunity to make a significant contribution to the development of life-changing medicines.
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Research Scientist - Drug Discovery

SO15 0AA Southampton, South East £55000 Annually WhatJobs

Posted 4 days ago

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full-time
Our client, a dynamic pharmaceutical company, is seeking a dedicated Research Scientist to join their drug discovery team in Southampton, Hampshire, UK . This role offers a hybrid working arrangement, allowing for a blend of laboratory-based research and remote data analysis and reporting. The successful candidate will contribute to the identification and development of novel therapeutic agents. You will be involved in experimental design, execution, data analysis, and interpretation within a collaborative research environment. The ideal candidate will possess a strong background in molecular biology, biochemistry, or a related life science discipline, with hands-on experience in relevant laboratory techniques. A passion for scientific innovation and a commitment to advancing healthcare are essential. Responsibilities include:

  • Designing and conducting in vitro and in vivo experiments to support drug discovery programs.
  • Utilising a range of molecular biology, cell biology, and biochemical techniques.
  • Analysing and interpreting complex experimental data, preparing comprehensive reports.
  • Collaborating with cross-functional teams, including chemists, pharmacologists, and clinicians.
  • Contributing to the development of new research methodologies and protocols.
  • Maintaining accurate and detailed laboratory notebooks and research records.
  • Staying abreast of scientific literature and emerging trends in pharmaceutical research.
  • Presenting research findings at internal and external scientific meetings.
  • Assisting in the identification and validation of new drug targets.
  • Ensuring compliance with all safety and regulatory guidelines in the laboratory.

Qualifications:
  • A PhD or MSc in Molecular Biology, Biochemistry, Pharmacology, or a related field.
  • Proven experience in drug discovery research, preferably within the pharmaceutical or biotech industry.
  • Hands-on experience with relevant laboratory techniques such as cell culture, Western blotting, ELISA, PCR, and flow cytometry.
  • Strong analytical and problem-solving skills.
  • Excellent written and oral communication skills.
  • Ability to work effectively both independently and as part of a multidisciplinary team.
  • Experience with data analysis software (e.g., GraphPad Prism, R) is a plus.
  • Familiarity with assay development and validation.
  • A proactive approach to research and a commitment to scientific rigor.

This is an exciting opportunity for a talented scientist to contribute to the development of life-saving medicines from our state-of-the-art facilities in Southampton.
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Research Scientist - Drug Discovery

SR3 3PX Sunderland, North East £50000 Annually WhatJobs

Posted 9 days ago

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full-time
Our client, a leading pharmaceutical innovator based in Sunderland, is seeking a talented Research Scientist to join their cutting-edge Drug Discovery division. This hybrid role offers a compelling blend of in-lab experimentation and remote data analysis, contributing to the development of novel therapeutics. You will be instrumental in designing and executing complex biological assays, investigating novel targets, and contributing to lead optimization campaigns. Your responsibilities will include performing cell-based assays, biochemical assays, and phenotypic screening to evaluate the efficacy and safety of new drug candidates. You will meticulously document experimental procedures and results, maintaining high standards of scientific rigor. Data analysis, interpretation, and presentation of findings to the research team and cross-functional collaborators will be a key aspect of your role. You will also stay abreast of the latest scientific literature and technological advancements relevant to drug discovery. The ideal candidate will possess a PhD or Master's degree in a relevant biological science (e.g., Pharmacology, Molecular Biology, Biochemistry) with a strong publication record and hands-on experience in small molecule or biologics drug discovery. Expertise in specific assay development, high-throughput screening, and molecular biology techniques is essential. Experience with data analysis software (e.g., GraphPad Prism, Spotfire) and a good understanding of medicinal chemistry principles are highly desirable. Strong problem-solving skills, excellent communication abilities, and the capacity to work independently as well as collaboratively in a dynamic, fast-paced research environment are crucial. This is an exceptional opportunity to make a significant contribution to advancing human health, working within a state-of-the-art facility and a team of dedicated scientists. Embrace the opportunity to shape the future of medicine in a role that combines focused lab work with the flexibility of remote contribution.
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Research Scientist - Drug Discovery

CF10 1EU Cardiff, Wales £40000 Annually WhatJobs

Posted 16 days ago

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full-time
Our client, a leading pharmaceutical research organisation, is seeking a talented Research Scientist to join their drug discovery team based in **Cardiff, Wales, UK**. This is a laboratory-based role focused on innovative research to identify and validate novel therapeutic targets. The successful candidate will play a key role in the early stages of drug development, contributing to the creation of next-generation medicines.

Key Responsibilities:
  • Design and execute complex experiments to investigate biological pathways and identify potential drug targets.
  • Utilise a range of molecular and cellular biology techniques, including cell culture, assays, and biochemical methods.
  • Analyse experimental data rigorously, interpret results, and present findings to internal teams and stakeholders.
  • Contribute to the development and optimisation of new research methodologies and assays.
  • Collaborate effectively with interdisciplinary teams, including chemists, pharmacologists, and bioinformaticians.
  • Maintain detailed and accurate laboratory notebooks and research records.
  • Stay abreast of the latest scientific literature and advancements in pharmaceutical research and relevant therapeutic areas.
  • Operate and maintain laboratory equipment to a high standard.
  • Contribute to the preparation of scientific publications and patent applications.
  • Ensure all laboratory activities are conducted in compliance with safety regulations and Good Laboratory Practice (GLP).
  • Participate in scientific meetings and contribute to project strategy discussions.
  • Mentor junior research assistants or interns as required.
Essential Qualifications and Experience:
  • PhD in a relevant life science discipline (e.g., Molecular Biology, Biochemistry, Pharmacology, Immunology).
  • Post-doctoral research experience or equivalent industry experience in drug discovery or a related field.
  • Hands-on experience with a broad range of molecular and cellular biology techniques.
  • Proven ability to design, execute, and interpret complex biological experiments.
  • Strong analytical skills and a meticulous approach to data analysis and reporting.
  • Excellent understanding of disease mechanisms and drug discovery processes.
  • Proficiency in scientific literature searching and critical evaluation of research papers.
  • Strong written and verbal communication skills, with the ability to present complex scientific information clearly.
  • Ability to work independently and collaboratively within a team environment.
  • Experience with relevant software for data analysis and experimental design is desirable.
This is a pivotal role for a skilled scientist looking to make a tangible impact on the development of new medicines within a cutting-edge research environment.
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Principal Scientist - Drug Discovery & Development

MK9 2EB Milton Keynes, South East £70000 Annually WhatJobs

Posted 5 days ago

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full-time
Our client, a pioneering biotechnology company at the forefront of therapeutic innovation, is seeking a highly accomplished Principal Scientist to lead critical research initiatives within their Drug Discovery & Development division. Based in Milton Keynes, Buckinghamshire, UK , this role is integral to advancing novel treatment modalities from early-stage research through to preclinical development. The successful candidate will bring a wealth of scientific expertise, a proven track record in research leadership, and a passion for translating scientific breakthroughs into life-changing medicines. This is a lab-based role requiring hands-on involvement and direct oversight of research activities.

Key Responsibilities:
  • Design, execute, and interpret complex experiments to drive drug discovery programmes forward.
  • Lead and mentor a team of talented research scientists and technicians, fostering a culture of scientific excellence and collaboration.
  • Develop and validate novel assays and technologies to support drug discovery efforts.
  • Identify and evaluate promising therapeutic targets and lead compounds.
  • Oversee preclinical studies, including in vitro and in vivo models, to assess compound efficacy and safety.
  • Collaborate effectively with cross-functional teams, including chemistry, pharmacology, toxicology, and translational science.
  • Author high-quality scientific reports, manuscripts, and patent applications.
  • Present research findings at internal meetings and external scientific conferences.
  • Manage external collaborations with academic institutions and contract research organizations (CROs).
  • Contribute to strategic planning for the R&D pipeline and portfolio management.
  • Ensure compliance with all relevant laboratory safety regulations and best practices.
  • Stay abreast of the latest scientific advancements and competitive landscape in relevant therapeutic areas.
Required Qualifications and Expertise:
  • Ph.D. in Pharmacology, Molecular Biology, Biochemistry, Immunology, or a related life science discipline.
  • Minimum of 10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry, with a strong focus on drug discovery.
  • Demonstrated leadership experience in managing scientific teams and projects.
  • Deep expertise in (Specific therapeutic area relevant to fictional company, e.g., oncology, infectious diseases, neuroscience) and associated drug discovery methodologies.
  • Proficiency in a wide range of in vitro and in vivo experimental techniques.
  • Proven ability to design and execute complex research strategies and troubleshoot effectively.
  • Excellent analytical, problem-solving, and critical thinking skills.
  • Exceptional written and verbal communication skills, with a track record of publications and presentations.
  • Experience with biostatistics and data analysis software.
  • Strong project management skills and the ability to manage multiple priorities.
  • A passion for scientific innovation and a commitment to developing novel therapeutics.
This is an exceptional opportunity for a distinguished scientist to make a significant impact on the future of medicine. Join a world-class research team and contribute to the development of groundbreaking therapies.
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Principal Scientist - Drug Discovery & Development

G2 1EU Glasgow, Scotland £80000 Annually WhatJobs

Posted 9 days ago

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full-time
Our client, a renowned pharmaceutical research and development company located in Glasgow, Scotland, UK , is seeking a highly accomplished Principal Scientist to lead critical initiatives in drug discovery and development. This senior role is responsible for driving innovation, designing experimental strategies, and executing complex research projects aimed at identifying and advancing novel therapeutic candidates. You will play a key part in shaping the company's R&D pipeline, leveraging your deep scientific expertise to overcome research challenges and accelerate the progression of drug candidates through preclinical and early clinical stages. The ideal candidate will possess a strong track record in medicinal chemistry, pharmacology, or a related discipline, with a comprehensive understanding of the drug discovery process from target identification to candidate selection. Proven experience in leading scientific teams, managing research projects, and mentoring junior scientists is essential. You must demonstrate excellent analytical and problem-solving skills, with the ability to interpret complex data, draw insightful conclusions, and make critical research decisions. Strong communication and presentation skills are required to effectively convey scientific findings to internal stakeholders, including senior management and cross-functional teams, as well as external collaborators. Proficiency with relevant laboratory techniques, data analysis software, and scientific literature databases is expected. This hybrid position offers the benefit of collaborative laboratory work and team meetings, combined with the flexibility of focused remote work. We are looking for a visionary scientific leader with a passion for innovation and a commitment to developing life-changing medicines. A Ph.D. in a relevant scientific field (e.g., Pharmacology, Medicinal Chemistry, Biochemistry) and a minimum of 10 years of progressive experience in the pharmaceutical industry are required. Join our esteemed team in Glasgow and make a significant impact on global health.
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Principal Scientist - Drug Discovery & Development

ST1 5NB Staffordshire, West Midlands £75000 Annually WhatJobs

Posted 9 days ago

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full-time
Our client, a rapidly growing pharmaceutical company dedicated to discovering and developing life-changing medicines, is seeking a highly accomplished Principal Scientist to join their remote-first research team. This pivotal role is essential for driving innovation in drug discovery and development. You will leverage your deep scientific expertise to design and execute complex research projects, mentor junior scientists, and contribute to strategic decision-making. This is an exceptional opportunity to make a tangible impact on patient lives from the comfort of your home office.

Key Responsibilities:
  • Lead and execute complex research projects focused on novel therapeutic targets and drug candidates.
  • Design and implement in vitro and in vivo experimental studies to assess drug efficacy, safety, and pharmacokinetics.
  • Analyze and interpret complex biological data, drawing insightful conclusions and proposing next steps.
  • Develop and validate new assays and methodologies to support drug discovery programs.
  • Collaborate effectively with internal teams (chemistry, biology, DMPK) and external partners to advance pipeline projects.
  • Provide scientific leadership and mentorship to junior scientists and research associates.
  • Stay at the forefront of scientific literature, identifying emerging trends and opportunities in pharmaceutical research.
  • Prepare high-quality scientific reports, presentations, and manuscripts for internal and external dissemination.
  • Contribute to the strategic direction of the company's research pipeline and portfolio.
Qualifications:
  • PhD in Molecular Biology, Pharmacology, Biochemistry, or a related life science discipline.
  • 10+ years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
  • Proven track record of successfully leading drug discovery projects from target identification through preclinical development.
  • Extensive experience with various biological assays, molecular biology techniques, and cell-based models.
  • Strong understanding of immunology, oncology, or other relevant therapeutic areas.
  • Demonstrated ability to design, execute, and interpret complex experiments.
  • Exceptional critical thinking, problem-solving, and analytical skills.
  • Excellent written and verbal communication skills, with a talent for presenting complex scientific information.
  • Experience mentoring and managing scientific staff is essential.
This fully remote position, located conceptually near Stoke-on-Trent, Staffordshire, UK , offers a unique chance to join a forward-thinking organisation committed to scientific excellence and innovation in pharmaceutical research. If you are a visionary scientist ready to lead groundbreaking research, we want to hear from you.
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Principal Scientist - Drug Discovery & Development

BD3 0HF Bradford, Yorkshire and the Humber £75000 Annually WhatJobs

Posted 19 days ago

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full-time
Our client is a leading pharmaceutical innovator seeking a highly accomplished Principal Scientist to drive critical drug discovery and development initiatives within their state-of-the-art research facility located in **Bradford, West Yorkshire, UK**. This pivotal role involves leading complex research projects, from target identification and validation through to preclinical development, contributing significantly to the company's pipeline of novel therapeutics. You will leverage your deep scientific expertise and extensive experience to guide research strategies, foster innovation, and ensure the efficient progression of drug candidates.

Key Responsibilities:
  • Lead and manage multiple drug discovery projects from concept to preclinical candidate selection.
  • Design and execute complex biological experiments to investigate disease mechanisms and identify novel therapeutic targets.
  • Develop and optimize assay development strategies for high-throughput screening and compound characterization.
  • Analyze and interpret experimental data, making critical decisions on project direction and go/no-go criteria.
  • Collaborate closely with internal teams (e.g., medicinal chemistry, pharmacology, DMPK) and external partners to advance drug candidates.
  • Stay current with scientific literature and emerging technologies in relevant therapeutic areas and drug discovery methodologies.
  • Prepare and present research findings to senior management, scientific committees, and at external conferences.
  • Contribute to the development of intellectual property and regulatory submissions.
  • Mentor and guide junior scientists, fostering a culture of scientific excellence and collaboration.
  • Ensure compliance with all relevant safety, ethical, and regulatory guidelines.
Required Qualifications:
  • Ph.D. in Molecular Biology, Biochemistry, Pharmacology, or a closely related life science discipline.
  • A minimum of 8-10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
  • Demonstrated success in leading drug discovery projects and bringing candidates into preclinical development.
  • Extensive knowledge of various drug discovery platforms and modalities (e.g., small molecules, biologics).
  • Proficiency in experimental design, data analysis, and interpretation using relevant software.
  • Excellent understanding of relevant therapeutic areas (e.g., oncology, immunology, neuroscience).
  • Strong leadership, project management, and communication skills.
  • Proven ability to work effectively in a multidisciplinary, matrixed environment.
  • Experience with manuscript preparation and scientific presentation is essential.
  • A strong publication record in peer-reviewed journals is highly desirable.
This is a challenging and rewarding role for a seasoned scientist eager to make a substantial impact on the development of life-saving medicines. Join a dynamic team dedicated to advancing pharmaceutical science in **Bradford, West Yorkshire, UK**.
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Principal Scientist, Drug Discovery

BT2 8DL Belfast, Northern Ireland £90000 Annually WhatJobs

Posted today

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full-time
Our client, a cutting-edge biotechnology firm dedicated to discovering life-changing therapeutics, is looking for a highly experienced Principal Scientist to lead critical research initiatives within their drug discovery division. This is a fully remote, senior-level position for an individual with a distinguished track record in pharmaceutical research and development. You will spearhead innovative research programmes, focusing on novel target identification and validation, and lead the design and execution of experiments to discover and characterise potential drug candidates. The role involves extensive collaboration with internal multidisciplinary teams (chemistry, biology, pharmacology) and external academic collaborators and CROs. You will be responsible for developing and implementing robust experimental strategies, interpreting complex data sets, and making critical decisions regarding project progression. A significant aspect of your role will be mentoring junior scientists, fostering a culture of scientific excellence, innovation, and rigorous data analysis. You will also contribute to intellectual property strategy and the preparation of scientific publications and regulatory filings. The ideal candidate will possess a deep understanding of modern drug discovery approaches, including small molecule and/or biologics development, and possess expertise in a relevant therapeutic area. Exceptional critical thinking, problem-solving abilities, and a passion for pushing the boundaries of scientific discovery are essential. As a fully remote role, you will leverage advanced virtual communication and collaboration tools to maintain seamless teamwork and project momentum. This is an exceptional opportunity to make a significant impact on human health from the comfort of your home office. The **Belfast, Northern Ireland, UK** based company offers this unique opportunity to work remotely.
Responsibilities:
  • Lead and design innovative drug discovery research programmes.
  • Identify and validate novel therapeutic targets.
  • Develop and execute experimental strategies for drug discovery and characterisation.
  • Interpret complex biological and pharmacological data.
  • Mentor and guide junior scientists and research associates.
  • Collaborate effectively with internal teams, academic partners, and CROs.
  • Contribute to patent filings and scientific publications.
  • Stay abreast of scientific literature and emerging technologies in drug discovery.
  • Contribute to strategic planning and decision-making for the R&D pipeline.
Qualifications:
  • PhD in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline.
  • 10+ years of post-doctoral experience in drug discovery within the pharmaceutical or biotech industry.
  • Demonstrated success in leading R&D projects from target identification to lead optimisation.
  • Expertise in a specific therapeutic area (e.g., oncology, immunology, neuroscience).
  • Proven ability to design and interpret complex biological experiments.
  • Excellent scientific communication, presentation, and writing skills.
  • Strong leadership and mentorship capabilities.
  • Experience with remote collaboration tools and working autonomously.
  • Publication record in high-impact scientific journals.
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Principal Scientist, Drug Discovery

BN1 1AA East Sussex, South East £75000 Annually WhatJobs

Posted 1 day ago

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full-time
Our client, a rapidly expanding biopharmaceutical company at the forefront of novel therapeutic development, is seeking an exceptional Principal Scientist to lead critical drug discovery initiatives. This is a fully remote position, offering the opportunity to contribute to groundbreaking research from anywhere in the UK. You will spearhead the design and execution of complex biological experiments, driving the identification and validation of new drug targets and lead compounds. As a vital member of our virtual R&D team, you will leverage your deep scientific expertise to shape our pipeline and contribute to the development of life-changing medicines.

Key Responsibilities:
  • Design, implement, and interpret complex biological assays and experiments to identify and validate novel drug targets and mechanisms of action.
  • Lead cross-functional research teams in the discovery and optimization of small molecule or biologic drug candidates.
  • Develop and implement cutting-edge research strategies aligned with therapeutic area objectives.
  • Analyze and interpret large datasets using statistical and bioinformatics tools to guide experimental design and decision-making.
  • Manage external collaborations with academic institutions and contract research organizations (CROs).
  • Author high-quality research reports, manuscripts for publication, and presentations for scientific conferences.
  • Contribute to the intellectual property strategy through invention disclosures and patent filings.
  • Mentor and train junior scientists, fostering a collaborative and innovative research environment.
  • Stay current with the latest scientific literature, technologies, and trends in drug discovery and relevant therapeutic areas.
  • Ensure rigorous adherence to laboratory safety protocols and good experimental practices.
Qualifications:
  • Ph.D. in Molecular Biology, Biochemistry, Pharmacology, or a related life science discipline.
  • A minimum of 8 years of post-doctoral and/or industry experience in drug discovery, with a strong publication record.
  • Demonstrated expertise in a specific therapeutic area (e.g., oncology, immunology, neurology) and relevant disease biology.
  • Proven track record of successfully leading drug discovery projects from target identification through lead optimization.
  • Extensive experience with a range of biochemical, cellular, and phenotypic assay development and execution.
  • Proficiency in data analysis software and bioinformatics tools.
  • Excellent critical thinking, problem-solving, and experimental design skills.
  • Strong written and verbal communication skills, with the ability to articulate complex scientific concepts to diverse audiences.
  • Experience managing projects and mentoring scientific staff.
  • Ability to thrive in a fast-paced, dynamic, and remote research environment.
Join our innovative remote team and play a pivotal role in advancing novel therapeutics from concept to clinic.
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