284 Clinical Data Manager jobs in the United Kingdom

Senior Clinical Data Manager

WUL Wolverhampton, West Midlands £60000 Annually WhatJobs

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full-time
Our client, a prestigious global Legal firm, is seeking a highly skilled and detail-oriented Senior Clinical Data Manager to join their team. This is a fully remote position, offering the flexibility to work from anywhere within the UK.

In this vital role, you will be responsible for the end-to-end management of clinical trial data, ensuring its accuracy, integrity, and compliance with regulatory standards. You will lead data management activities for multiple clinical studies, collaborating closely with clinical operations, biostatistics, and regulatory affairs teams.

Key responsibilities include developing and implementing data management plans, designing clinical databases, managing data validation processes, and overseeing data cleaning activities. You will ensure that all data management activities adhere to Good Clinical Practice (GCP) guidelines and relevant data privacy regulations. Experience with various Electronic Data Capture (EDC) systems and a strong understanding of clinical trial processes are essential.

The ideal candidate will possess a Bachelor's or Master's degree in a relevant scientific or healthcare field, with extensive experience in clinical data management. Strong leadership and project management skills are required, along with excellent analytical and problem-solving abilities. You must be adept at interpreting complex data, identifying potential issues, and implementing effective solutions. Exceptional communication and interpersonal skills are crucial for collaborating with internal teams and external partners. This is an exceptional opportunity for an experienced data professional to make a significant contribution to life-changing research.

Responsibilities:
  • Lead and manage all aspects of clinical data management for assigned studies.
  • Develop and implement comprehensive Data Management Plans (DMPs).
  • Design, build, and maintain clinical databases using EDC systems.
  • Define data validation rules and perform data cleaning activities to ensure data integrity.
  • Oversee user acceptance testing (UAT) of clinical databases.
  • Generate data management reports and metrics for study progress.
  • Ensure compliance with GCP, ICH guidelines, and data privacy regulations (e.g., GDPR).
  • Collaborate with Clinical Operations, Biostatistics, and Medical teams to address data-related queries.
  • Participate in the selection and implementation of new data management technologies.
  • Contribute to the development and training of junior data management personnel.
Qualifications:
  • Bachelor's or Master's degree in Life Sciences, Computer Science, Statistics, or a related field.
  • Minimum of 7 years of progressive experience in clinical data management.
  • Proven experience managing data for Phase I-IV clinical trials.
  • Proficiency with multiple Electronic Data Capture (EDC) systems (e.g., Medidata Rave, Oracle Clinical, Veeva EDC).
  • Strong understanding of clinical trial processes and regulatory requirements (GCP, ICH).
  • Excellent understanding of database design, data validation, and data reconciliation.
  • Strong analytical, problem-solving, and critical thinking skills.
  • Exceptional written and verbal communication skills.
  • Ability to manage multiple projects simultaneously and prioritize tasks effectively.
  • Experience with data standardization (e.g., CDISC SDTM/ADaM) is highly desirable.
This fully remote role offers a chance to be at the forefront of clinical research data integrity.
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Senior Clinical Data Manager

SO15 0AB Southampton, South East £70000 Annually WhatJobs

Posted 1 day ago

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full-time
Our client, a globally recognized pharmaceutical company at the forefront of innovative drug development, is actively seeking a highly skilled and experienced Senior Clinical Data Manager to join their expanding, fully remote team. In this critical role, you will be instrumental in ensuring the integrity, quality, and timeliness of clinical trial data across multiple therapeutic areas. You will be responsible for the design, development, and implementation of data management plans (DMPs), database setup, data validation strategies, and end-user training. Your expertise will be vital in overseeing the end-to-end data management process, from database lock to archiving, ensuring compliance with all relevant regulatory guidelines (e.g., ICH GCP, FDA). This position demands a meticulous approach to data handling, meticulous attention to detail, and a deep understanding of clinical trial methodologies and data standards (CDISC SDTM/ADAM). You will collaborate closely with internal stakeholders, including Clinical Operations, Biostatistics, and Statistical Programming, as well as external partners such as Contract Research Organizations (CROs). Responsibilities include leading data review meetings, resolving data discrepancies, managing data entry quality, and ensuring data consistency and accuracy. The ability to interpret complex protocols and translate them into robust data management systems is essential. As a remote-first position, exceptional communication, organizational, and self-management skills are paramount. You will need to proactively engage with teams across different time zones and maintain strong working relationships without direct physical proximity. We are looking for a strategic thinker who can contribute to process improvements and mentor junior data management staff. A minimum of 8 years of progressive experience in clinical data management within the pharmaceutical or biotech industry is required. A Bachelor's or Master's degree in a scientific or related field is preferred. Proficiency in Electronic Data Capture (EDC) systems (e.g., Medidata Rave, Oracle Clinical) and familiarity with CDISC standards are mandatory. This is an exceptional opportunity to make a significant impact on the development of life-saving medicines from the comfort of your home office, contributing to groundbreaking research and development initiatives for our client.
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Principal Clinical Data Manager

S1 1DA Sheffield, Yorkshire and the Humber £85000 Annually WhatJobs

Posted 7 days ago

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full-time
A leading pharmaceutical research organization is seeking a highly skilled Principal Clinical Data Manager for their operations in Sheffield, South Yorkshire, UK . This role is pivotal in ensuring the integrity, accuracy, and quality of clinical trial data. You will be responsible for overseeing all aspects of clinical data management, from database design and setup to data validation, cleaning, and database lock. Your expertise will ensure compliance with regulatory requirements and company standards.

Key responsibilities include developing clinical data management plans, creating data validation specifications, and managing external vendors involved in data management activities. You will lead and mentor a team of data managers, providing guidance and support to ensure efficient and effective data collection and processing. The ideal candidate will possess a Bachelor's or Master's degree in a scientific or healthcare-related field, with a minimum of 8 years of experience in clinical data management, including significant experience in a leadership or principal role. A strong understanding of clinical trial processes, CDISC standards (SDTM, ADaM), and various EDC systems (e.g., Medidata Rave, Oracle Clinical) is essential. Excellent analytical, problem-solving, and communication skills are required, along with meticulous attention to detail. Experience with database programming and query writing is highly desirable. This is an excellent opportunity to contribute to critical drug development programs and advance your career in a highly respected pharmaceutical organization.
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Senior Clinical Data Manager

L3 9DT Liverpool, North West £55000 Annually WhatJobs

Posted 15 days ago

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full-time
Our client is seeking a highly experienced and meticulous Senior Clinical Data Manager to join their dynamic pharmaceutical research team. This role plays a critical part in ensuring the integrity, accuracy, and reliability of clinical trial data, which is essential for regulatory submissions and drug development. You will be responsible for overseeing the design, development, and execution of clinical databases, managing data entry processes, and ensuring compliance with all relevant data management standards and regulatory guidelines (e.g., ICH GCP). The Senior Clinical Data Manager will lead data management activities across multiple clinical trials, collaborating closely with clinical operations, biostatistics, and medical coding teams. Key responsibilities include developing data management plans (DMPs), creating case report forms (CRFs), establishing data validation checks, and performing data cleaning activities. You will also manage user acceptance testing (UAT) for clinical databases and work with external vendors as needed. This position requires a strong understanding of clinical trial processes, database technologies (e.g., EDC systems like Medidata Rave, Oracle Clinical), and data quality principles. The ideal candidate will possess excellent analytical and problem-solving skills, with a keen eye for detail and a commitment to data accuracy. Leadership potential and the ability to mentor junior data managers are highly valued. While this role offers a hybrid work arrangement, flexibility to attend key meetings on-site in Liverpool will be expected. You will contribute significantly to the successful execution of clinical studies, ensuring that high-quality data supports critical research outcomes.

Responsibilities:
  • Develop and implement comprehensive Data Management Plans (DMPs) for clinical trials.
  • Design, build, and maintain clinical databases using Electronic Data Capture (EDC) systems.
  • Oversee the creation and validation of Case Report Forms (CRFs) and data entry guidelines.
  • Establish and execute data validation procedures, including query generation and resolution.
  • Ensure data accuracy, completeness, and consistency throughout the clinical trial lifecycle.
  • Perform data review and cleaning activities in accordance with protocols and DMPs.
  • Manage User Acceptance Testing (UAT) for clinical databases and related systems.
  • Collaborate with cross-functional teams, including biostatistics, clinical operations, and regulatory affairs.
  • Ensure compliance with Good Clinical Practice (GCP), ICH guidelines, and other relevant regulations.
  • Contribute to the development and maintenance of standard operating procedures (SOPs) for data management.
  • Act as a subject matter expert for clinical data management within the organisation.
  • Mentor and provide guidance to junior clinical data management personnel.
Qualifications:
  • Bachelor's degree in a life science, computer science, or related field.
  • Minimum of 5 years of experience in clinical data management within the pharmaceutical or biotech industry.
  • Proven experience with EDC systems (e.g., Medidata Rave, Oracle Clinical, Veeva).
  • Strong understanding of ICH-GCP guidelines and regulatory requirements for clinical data.
  • Excellent knowledge of database design, data validation, and data cleaning processes.
  • Proficiency in clinical trial methodologies and terminology.
  • Strong analytical and problem-solving abilities with meticulous attention to detail.
  • Effective communication and interpersonal skills, with the ability to work collaboratively in a hybrid team environment.
  • Experience in leading data management activities for multiple studies is advantageous.
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Principal Clinical Data Manager

L1 8JQ Liverpool, North West £75000 Annually WhatJobs

Posted 22 days ago

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full-time
Our client, a leading pharmaceutical research organization, is seeking a Principal Clinical Data Manager to join their globally distributed team. This is a fully remote position, offering the flexibility to work from anywhere while contributing to critical pharmaceutical development projects. You will be responsible for overseeing the design, development, and implementation of clinical databases, ensuring data integrity, accuracy, and compliance with regulatory standards. This senior role requires extensive experience in clinical data management, a deep understanding of CDISC standards, and strong leadership capabilities. You will play a crucial role in the success of clinical trials, ensuring that data is managed efficiently and effectively to support regulatory submissions and therapeutic advancements.

Key Responsibilities:
  • Lead the design, setup, and maintenance of clinical databases according to study protocols and therapeutic area requirements.
  • Develop and implement data management plans (DMPs), edit check specifications, and data validation procedures.
  • Oversee data cleaning activities, issue resolution, and database lock processes for clinical trials.
  • Ensure compliance with Good Clinical Practice (GCP), FDA regulations, ICH guidelines, and other relevant regulatory requirements.
  • Develop and maintain standard operating procedures (SOPs) and work instructions for clinical data management.
  • Provide technical expertise and guidance on clinical data management best practices.
  • Mentor and train junior data managers and data management staff.
  • Act as a key point of contact for data management activities, collaborating with clinical operations, biostatistics, programming, and medical teams.
  • Participate in the selection and implementation of data management technologies and tools.
  • Conduct quality control checks and audits to ensure data accuracy and consistency.
  • Contribute to the development of integrated data management strategies across multiple projects and therapeutic areas.
  • Review and approve data management-related documents, including CRFs, database specifications, and validation reports.
  • Proactively identify risks and issues related to data management and implement mitigation strategies.
  • Stay current with industry trends, regulatory changes, and advancements in clinical data management.

Required Qualifications:
  • Bachelor's degree in a scientific, technical, or health-related field. Master's degree preferred.
  • Minimum of 10 years of progressive experience in clinical data management within the pharmaceutical or biotechnology industry.
  • Extensive knowledge of clinical trial processes and regulatory requirements (GCP, ICH, FDA).
  • Proficiency in CDISC standards (SDTM, ADaM) and experience with data warehousing solutions.
  • Strong experience with clinical data management systems (e.g., Medidata Rave, Oracle Clinical, SAS).
  • Proven ability to lead data management activities for complex, global clinical trials.
  • Excellent understanding of database design, data validation techniques, and data cleaning processes.
  • Strong leadership, project management, and problem-solving skills.
  • Exceptional communication, presentation, and interpersonal skills.
  • Ability to work independently and collaboratively in a remote team environment.
  • Experience in mentoring and developing data management professionals.

This fully remote role offers a significant opportunity to influence drug development and advance your career at the forefront of pharmaceutical innovation.
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Remote Clinical Data Manager

M1 1AA Manchester, North West £65000 Annually WhatJobs

Posted 25 days ago

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full-time
This is a fully remote opportunity for a skilled Clinical Data Manager to join a leading global pharmaceutical research organization. Our client is at the forefront of developing life-changing therapies and seeks a dedicated professional to manage and oversee clinical trial data from study start-up through database lock. You will be responsible for developing Data Management Plans (DMPs), designing Case Report Forms (CRFs), and establishing data validation checks and edit specifications in accordance with protocol requirements and regulatory guidelines (e.g., ICH GCP). This role involves leading data cleaning activities, ensuring the accuracy, completeness, and integrity of clinical trial data. You will collaborate closely with biostatisticians, clinical research associates (CRAs), study managers, and external vendors to resolve data discrepancies and queries in a timely manner. Database validation and User Acceptance Testing (UAT) will be key responsibilities, ensuring the clinical database meets all functional and data integrity requirements. You will also contribute to the development and maintenance of data management SOPs and work instructions. A strong understanding of CDISC standards (SDTM and ADaM) and EDC systems (e.g., Medidata Rave, Oracle InForm) is essential. Experience in managing data for Phase I-IV clinical trials across various therapeutic areas is highly desirable. The ideal candidate will possess a Bachelor's degree in a scientific discipline, computer science, or a related field, with a minimum of 5 years of experience in clinical data management within the pharmaceutical or biotechnology industry. Exceptional attention to detail, strong organizational skills, and the ability to manage multiple projects simultaneously are crucial. Excellent communication and interpersonal skills are necessary for effective remote collaboration. This is a remote-first position, offering the flexibility to work from anywhere within the UK, with regular virtual team meetings and collaboration. If you are a proactive and experienced Clinical Data Manager looking for a challenging and rewarding remote role, we encourage you to apply.
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Lead Clinical Data Manager (Remote)

RG1 1DA Reading, South East £75000 Annually WhatJobs

Posted 7 days ago

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full-time
Our client, a rapidly growing biopharmaceutical company focused on developing life-changing therapies, is looking for an experienced and detail-oriented Lead Clinical Data Manager to join their globally distributed team. This is a fully remote position, offering the flexibility to work from anywhere within the UK. You will play a critical role in ensuring the integrity, quality, and accuracy of clinical trial data across multiple studies, from database setup to database lock.

As the Lead Clinical Data Manager, you will be responsible for overseeing all aspects of clinical data management activities, including database design and development, data validation strategy, UAT, and the execution of data review and cleaning processes. You will manage a team of data managers, providing guidance, mentorship, and ensuring adherence to global regulatory standards (e.g., ICH-GCP, FDA regulations). This role requires a deep understanding of clinical trial processes, EDC systems, and data standards (e.g., CDISC). You will collaborate closely with clinical operations, biostatistics, programming, and medical teams to ensure timely and high-quality data delivery.

Key Responsibilities:
  • Lead and manage global clinical data management activities for assigned clinical trials.
  • Oversee the design, build, testing, and validation of clinical databases using Electronic Data Capture (EDC) systems.
  • Develop and implement comprehensive data management plans (DMPs), data validation plans, and data review guidelines.
  • Manage data cleaning activities, including query generation and resolution, ensuring data accuracy and completeness.
  • Oversee the development and execution of User Acceptance Testing (UAT) for clinical databases and related tools.
  • Ensure compliance with ICH-GCP guidelines, regulatory requirements, and internal SOPs.
  • Lead the process of database lock for clinical studies, ensuring all data issues are resolved.
  • Manage and mentor a team of clinical data managers, fostering their professional development.
  • Liaise with external vendors, including CROs, for data management activities.
  • Contribute to the development and maintenance of departmental SOPs and work instructions.
  • Represent the data management function in cross-functional study team meetings and contribute to study-level strategy.
  • Ensure data standardization according to CDISC SDTM and ADaM requirements where applicable.
Qualifications:
  • Bachelor's degree in a life science, computer science, or related field.
  • A minimum of 7 years of experience in clinical data management within the pharmaceutical or biotech industry.
  • At least 2 years of experience in a lead or management role.
  • Extensive experience with various EDC systems (e.g., Medidata Rave, Oracle Clinical, Veeva Vault EDC).
  • Strong knowledge of clinical trial processes, regulatory requirements (ICH-GCP, FDA), and data standards (CDISC).
  • Proven ability to manage multiple projects simultaneously in a remote setting.
  • Excellent leadership, communication, and interpersonal skills.
  • Strong understanding of data quality control and validation methodologies.
  • Experience in managing and mentoring direct reports.
  • Ability to work independently and collaboratively in a fast-paced, global environment.
This remote position offers a competitive compensation package, excellent benefits, and the opportunity to contribute significantly to the advancement of novel therapeutics. Join a forward-thinking organization and make a difference from wherever you are.
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Senior Clinical Data Manager (Remote)

M1 4BG Manchester, North West £65000 Annually WhatJobs

Posted 23 days ago

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Job Description

full-time
Our client, a leading Contract Research Organisation (CRO) dedicated to advancing medical treatments, is actively seeking an experienced Senior Clinical Data Manager to join their growing, globally distributed team. This is a fully remote position, offering flexibility and the opportunity to contribute to critical clinical trials from the comfort of your own home. You will be responsible for overseeing the design, development, and execution of clinical databases, ensuring the integrity, accuracy, and quality of data collected during studies.

Key Responsibilities:
  • Lead the design, database build, and validation of clinical databases according to study protocols and regulatory requirements (e.g., CDISC, ICH GCP).
  • Develop Data Management Plans (DMPs) and contribute to other study-related documentation, such as CRFs, edit checks, and data validation plans.
  • Oversee the data cleaning process, including query generation, resolution, and reconciliation, ensuring timely and accurate data review.
  • Manage data entry and transfer activities, ensuring data integrity and compliance with SOPs.
  • Coordinate with cross-functional teams, including clinical operations, biostatistics, programming, and medical monitors, to ensure efficient data flow and issue resolution.
  • Provide guidance and mentorship to junior data managers and data management staff.
  • Ensure adherence to all relevant regulatory guidelines and industry standards throughout the data management lifecycle.
  • Participate in database validation activities, user acceptance testing (UAT), and system integration testing.
  • Contribute to the development and implementation of data management standards, SOPs, and best practices.
  • Manage multiple clinical studies simultaneously, ensuring all data management deliverables are met on time and within budget.
  • Act as a key point of contact for data management aspects during client audits and regulatory inspections.
  • Evaluate and implement new technologies and tools to enhance data management efficiency and quality.
  • Contribute to the proposal process by providing input on data management timelines and resource requirements.
  • Perform quality control checks on data management activities and deliverables.
Required Qualifications:
  • Bachelor's degree in a life science, computer science, or related field. Master's degree preferred.
  • A minimum of 5-7 years of experience in clinical data management within the pharmaceutical or CRO industry.
  • Extensive experience with EDC (Electronic Data Capture) systems (e.g., Medidata Rave, Oracle Clinical, Veeva EDC).
  • Strong understanding of clinical trial processes, data standards (CDISC), and regulatory requirements (ICH GCP, FDA).
  • Proficiency in database design, data validation, and query management.
  • Excellent leadership, communication, and interpersonal skills, with the ability to collaborate effectively in a remote team environment.
  • Strong analytical and problem-solving abilities with meticulous attention to detail.
  • Experience mentoring or supervising junior team members.
  • Ability to manage multiple projects simultaneously and prioritize effectively.
  • Proficiency in Microsoft Office Suite.
  • Must be based in the UK and eligible to work remotely.
This is an excellent opportunity for a skilled professional to make a significant contribution to life-saving research in a flexible, remote working environment. Applicants must have the unrestricted right to work in the UK.
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Senior Clinical Data Manager - Oncology Trials

CV1 1AA Coventry, West Midlands £65000 Annually WhatJobs

Posted 21 days ago

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full-time
Our client, a prominent contract research organisation (CRO) in the pharmaceutical sector, is seeking an experienced Senior Clinical Data Manager to oversee critical oncology clinical trials. This is a fully remote, permanent position, offering the flexibility to work from anywhere within the UK. You will be responsible for the end-to-end management of clinical trial data, ensuring its accuracy, integrity, and compliance with regulatory standards (e.g., FDA, EMA, ICH GCP). Your duties will include designing clinical databases, developing data management plans, leading data validation activities, and managing data entry and query resolution processes. You will collaborate closely with clinical operations, biostatistics, and regulatory affairs teams to ensure seamless data flow and timely database lock. The ideal candidate will possess a Bachelor's degree in a life science, health-related field, or computer science, along with at least 5-7 years of progressive experience in clinical data management, with a significant focus on oncology trials. Proficiency in EDC systems (e.g., Medidata Rave, Oracle Clinical) and strong knowledge of CDISC standards (SDTM, ADaM) are essential. Excellent analytical, problem-solving, and communication skills are required, along with meticulous attention to detail. You will mentor junior data managers, contribute to process improvements, and ensure adherence to standard operating procedures. This role requires a deep understanding of the drug development lifecycle and the critical role of high-quality data in supporting regulatory submissions and therapeutic advancements. If you are a dedicated data professional seeking a challenging and rewarding remote opportunity within a leading CRO, this role offers the chance to make a substantial impact on cancer research. This position is based in Coventry, West Midlands, UK , but operates entirely remotely.
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Principal Pharmaceutical Data Scientist

SW1A 0AA London, London £85000 Annually WhatJobs

Posted 13 days ago

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full-time
Our client, a leading innovator in the pharmaceutical sector, is seeking a highly experienced and visionary Principal Pharmaceutical Data Scientist to join their cutting-edge, fully remote research and development team. This critical role will focus on leveraging advanced data analytics, machine learning, and AI to accelerate drug discovery, optimize clinical trials, and enhance patient outcomes. You will be instrumental in shaping the data strategy for key therapeutic areas and translating complex biological and chemical data into actionable insights.

Responsibilities:
  • Lead the development and implementation of sophisticated data models and algorithms for predictive analytics in drug discovery and development.
  • Analyze large-scale omics data, clinical trial data, real-world evidence, and chemical structures to identify novel targets and biomarkers.
  • Design and build robust data pipelines for efficient data ingestion, processing, and storage, ensuring data integrity and scalability.
  • Collaborate closely with medicinal chemists, biologists, clinicians, and bioinformaticians to understand scientific challenges and provide data-driven solutions.
  • Develop and deploy machine learning models for tasks such as compound screening, efficacy prediction, patient stratification, and trial site selection.
  • Present complex findings and recommendations clearly and concisely to both technical and non-technical stakeholders across the organization.
  • Mentor junior data scientists and contribute to the overall technical growth of the data science team.
  • Stay at the forefront of scientific literature and technological advancements in bioinformatics, cheminformatics, and data science.
  • Contribute to the strategic direction of data science initiatives within the pharmaceutical R&D pipeline.
Qualifications:
  • Ph.D. or M.S. in Data Science, Computer Science, Statistics, Bioinformatics, Computational Chemistry, or a related quantitative field.
  • 10+ years of experience in data science, with a significant portion focused on the pharmaceutical or biotechnology industry.
  • Deep understanding of machine learning techniques, statistical modeling, and data mining.
  • Proficiency in programming languages such as Python or R, and relevant libraries (e.g., scikit-learn, TensorFlow, PyTorch).
  • Experience with big data technologies (e.g., Spark, Hadoop) and cloud platforms (AWS, Azure, GCP).
  • Strong knowledge of biological pathways, drug discovery processes, and clinical trial methodologies.
  • Excellent problem-solving skills and the ability to work independently and lead projects in a remote environment.
  • Exceptional communication and presentation skills.
This fully remote position offers a unique opportunity to work on groundbreaking pharmaceutical research from anywhere, contributing directly to the development of life-saving therapies. While the team operates remotely, the role is conceptually linked to our operations in London, England, UK .
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