What Principal Scientist Jobs are in the United Kingdom?

Showing 5000+ Principal Scientist jobs in the United Kingdom

Principal Scientist Biosensors

Stirling and Falkirk £70,000 - £86,000 Annually VRS-UK remove_red_eye View All

Posted 4 days ago

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Job Description

permanent

Are you an experienced R&D scientist with a background in biosensors, electrochemistry or diagnostic assay development? Are you looking to take the next step into a scientific leadership role within a rapidly growing, innovation-driven organisation?

We're partnering with an exciting nanotechnology company at the forefront of biosensor development, seeking a Principal Development Scientist to lead the development of next-generation diagnostic assays and sensor technologies.

This is an excellent opportunity for a senior or lead scientist with experience managing projects and mentoring teams to play a key role in bringing innovative technologies from concept through to commercialisation.

The Role

As Principal Development Scientist, you'll lead a small team of scientists while driving the technical development of novel biosensor technologies. Working within a collaborative R&D environment, you'll combine hands-on laboratory work with project leadership, scientific strategy and cross-functional collaboration.

Key Responsibilities

  • Lead the development of novel diagnostic assays and biosensor technologies.
  • Manage, mentor and develop a team of R&D scientists.
  • Design, execute and oversee complex experimental programmes.
  • Develop electrochemical methods and assay chemistries.
  • Drive technical decision-making and scientific strategy across development projects.
  • Prepare technical reports, protocols and development documentation.
  • Lead troubleshooting, root cause investigations and continuous improvement activities.
  • Support technology transfer, scale-up and product commercialisation.

The ideal candidate will have:

  • A PhD (or equivalent industrial experience) in Electrochemistry, Biochemistry, Biology, Analytical Chemistry, Nanotechnology or a related scientific discipline.
  • Significant industrial R&D experience within biosensors, medical devices or life sciences.
  • Strong expertise in electrochemical biosensors and diagnostic assay development.
  • Experience developing biofunctionalisation strategies and electrochemical sensing technologies.
  • A proven track record of leading scientific projects from research through to commercial application.
  • Previous experience managing, mentoring or supervising scientists.
  • Strong knowledge of GLP and working within regulated laboratory environments.
  • Excellent communication, leadership and technical problem-solving skills.

Why Apply?

  • Join an ambitious, fast-growing technology business developing next-generation diagnostic solutions.
  • Lead innovative R&D projects with real commercial impact.
  • Work in a collaborative environment where scientific ideas are encouraged and valued.
  • Excellent opportunities for career progression and professional development.
  • Competitive salary and comprehensive benefits package.

If you're an experienced Development Scientist ready to take on a senior technical leadership role within an innovative R&D environment, I'd love to hear from you.

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Principal Scientist - Structural Biology

City of Edinburgh  £60,000 - £90,000 per year  help_outline Stem Recruitment

Posted 3 days ago

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Job Description

permanent

We are seeking a Principal Scientist with extensive experience of Structural Biology to join a growing life sciences company based inEdinburgh. In this senior, laboratory-based position, you will utilise your extensive expertise in X-ray Crystallography, Cryo-EM, and structural biology to lead client projects, ensure high-quality delivery, and contribute to the growth of the service line. You will mentor colleagues, support training initiatives, and help to introduce new technologies to enhance laboratory capabilities. Your leadership and technical skills will directly impact the discovery and development programmes of various clients, while supporting the advancement of the team.

  • Deep expertise in Structural Biology, including hands-on experience with X-ray Crystallography and Cryo-EM
  • Proven experience leading scientific projects, especially in a CRO, biotech, pharma, or academic setting
  • Strong decision-making, communication skills, and ability to mentor junior scientists
  • PhD in industrial Structural Biology with a track record of successful scientific outcomes
  • Ability to interpret complex data and present results clearly to clients and teams
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Principal Scientist

Harwell  £60,000 - £90,000 per year  help_outline Lgc

Posted today

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Job Description

LGC Genomics and Diagnostics develops and manufactures a comprehensive portfolio of catalogue and custom‑developed diagnostic quality solutions and component materials for the extended life sciences industry. We partner with IVD assay developers, and pharmaceutical, CRO and academic institutions in commercialization activities across the entire diagnostic pipeline. Laboratorians and diagnostic professionals across disciplines of clinical chemistry, immunochemistry, serology, molecular diagnostics, and clinical genomics rely on LGC’s products to support accurate and reliable diagnostic results.

Our operating entities include Maine Standards Company, SeraCare Life Sciences, and Technopath Clinical Diagnostics, which are in vitro diagnostics (IVD) manufacturers of quality measurement tools (calibrators, controls, linearity, EQA/PT, biological materials), the Native Antigen Company, which is a manufacturer and supplier of viral antigens and LGC Proficiency Testing a global leader in PT schemes. We operate FDA‑registered and ISO 13485‑accredited facilities in Maine (USA), Massachusetts (USA), Maryland (USA), Tipperary (Ireland), ISO 9001‑accredited facility in Oxford, UK, and Traverse City, Michigan US.

Each day, our world‑class staff, scientific expertise, operational efficiency, and superior quality systems are ready to support the range of advanced technologies that collectively improve patient outcomes - from the widely adopted and established through to cutting‑edge NGS and precision diagnostics.

Job Description

We are seeking an experienced and highly motivated Principal Scientist to join LGC’s Research team. This is an outstanding opportunity for a technical expert with deep expertise in recombinant protein expression, virology, or microbiology. Experience in immunoassay development, antibody discovery, or display technologies is ideal.

As a Principal Scientist, you will direct complex scientific programmes covering new product development, technology innovation, and custom/co‑creation projects. You will function in a fast‑paced, collaborative environment, ensuring projects are finalized on time, within budget, and to the highest scientific standards.

Reporting directly to the Director of R&D, you will own project strategy, manage execution, and ensure delivery. You will also mentor colleagues and help foster a culture of continuous improvement and excellence.

Key Responsibilities

  • Lead and manage complex, multi‑disciplinary R&D projects, ensuring timely and efficient delivery.
  • Build and implement scientific project plans, workflows, and experimental strategies within your area of expertise.
  • Take full responsibility for project planning, costing, execution, and completion, often across multiple parallel workstreams.
  • Act as a technical authority, continuously refining methodologies and educating team members in your specialist domain.
  • Communicate effectively with internal and external collaborators. Present results and progress updates to senior management, customers, and the wider LGC organisation. Clearly explain the scientific rationale, technical challenges, and strategic value of projects.
  • Critically assess data and literature, confidently interpreting and communicating findings from published biological research to diverse audiences.
  • Identify and resolve technical challenges through structured root‑cause analysis and innovative problem‑solving.
  • Develop and maintain high‑quality documentation, including SOPs, protocols, and batch production records.
  • Work safely and confidently within a BSL‑2 laboratory, handling viral, bacterial, and protozoal pathogens in compliance with all relevant biosafety regulations.
  • Contribute to and thrive in a multidisciplinary, collaborative team environment, demonstrating strong organisational skills and accountability.

Qualifications

  • PhD in biology or related subjects; or equivalent scientific experience.
  • Minimum of 5 years of relevant experience in a R&D laboratory, ideally in a commercial entity.
  • Proven capability to guide intricate scientific projects from inception through to completion.
  • Strong analytical approach with the ability to troubleshoot and resolve scientific challenges independently.
  • Strong communication skills, able to convey complex technical concepts clearly to a variety of audiences.
  • Highly organised, proactive, and able to manage multiple projects under tight deadlines.
  • Confident in the use of MS Office (Word, Excel, PowerPoint) and AI tools.
  • Experience working in a quality regulated and/or biosafety level 2 environment is desirable.

LGC is committed to encouraging an inclusive and collaborative environment where every team member can succeed. Join us in our mission to deliver world‑class scientific solutions and make a significant impact in the research community. Your expertise and ambition will be instrumental in helping us achieve outstanding results!

Additional Information

ABOUT LGC:

LGC is a leading, global life science tools company, providing mission‑critical components and solutions into high‑growth application areas across the human healthcare and applied market segments. Its high‑quality product portfolio is comprised of mission‑critical tools for genomic analysis and for quality assurance applications, which are typically embedded and recurring within our customers’ products and workflows and are valued for their performance, quality, and range.

OUR VALUES

  • PASSION
  • CURIOSITY
  • INTEGRITY
  • BRILLIANCE
  • RESPECT

EQUAL OPPORTUNITIES

LGC strongly believes that every job applicant and employee should be valued for their individual talents regardless of age, disability, race, colour, ethnic or national origin, sex, sexual orientation, gender reassignment, marital or civil partnership, pregnancy or maternity, religion, or belief. Short listing, interviewing and selection will always be carried out without regard to gender, sexual orientation, marital status, colour, race, nationality, ethnic or national origins, religion or belief, age, or trade union membership.

Principal Scientist • Kidlington, OXFORDSHIRE, GB

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Principal Scientist

Harwell  £60,000 - £90,000 per year  help_outline Lgc Group

Posted today

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Job Description

We are seeking an experienced and highly motivated Principal Scientist to join LGC's Research team. This is an outstanding opportunity for a technical expert with deep expertise in recombinant protein expression, virology, or microbiology. Experience in immunoassay development, antibody discovery, or display technologies is ideal.

As a Principal Scientist, you will direct complex scientific programmes covering new product development, technology innovation, and custom/co-creation projects. You will function in a fast‑paced, collaborative environment, ensuring projects are finalized on time, within budget, and to the highest scientific standards.

Reporting directly to the Director of R&D, you will own project strategy, manage execution, and ensure delivery. You will also mentor colleagues and help foster a culture of continuous improvement and excellence.

Key Responsibilities
  • Lead and manage complex, multi‑disciplinary R&D projects, ensuring timely and efficient delivery.
  • Build and implement scientific project plans, workflows, and experimental strategies within your area of expertise.
  • Take full responsibility for project planning, costing, execution, and completion, often across multiple parallel workstreams.
  • Act as a technical authority, continuously refining methodologies and educating team members in your specialist domain.
  • Communicate effectively with internal and external collaborators. Present results and progress updates to senior management, customers, and the wider LGC organization. Clearly explain the scientific rationale, technical challenges, and strategic value of projects.
  • Critically assess data and literature, confidently interpreting and communicating findings from published biological research to diverse audiences.
  • Identify and resolve technical challenges through structured root‑cause analysis and innovative problem‑solving.
  • Develop and maintain high‑quality documentation, including SOPs, protocols, and batch production records.
  • Work safely and confidently within a BSL‑2 laboratory, handling viral, bacterial, and protozoal pathogens in compliance with all relevant biosafety regulations.
  • Contribute to and thrive in a multidisciplinary, collaborative team environment, demonstrating strong organisational skills and accountability.
Qualifications
  • PhD in biology or related subjects; or equivalent scientific experience.
  • Minimum of 5 years of relevant experience in a R&D laboratory, ideally in a commercial entity.
  • Proven capability to guide intricate scientific projects from inception through to completion.
  • Strong analytical approach with the ability to troubleshoot and resolve scientific challenges independently.
  • Strong communication skills, able to convey complex technical concepts clearly to a variety of audiences.
  • Highly organised, proactive, and able to manage multiple projects under tight deadlines.
  • Confident in the use of MS Office (Word, Excel, PowerPoint) and AI tools.
  • Experience working in a quality regulated and/or biosafety level 2 environment is desirable.

LGC is committed to encouraging an inclusive and collaborative environment where every team member can succeed. Join us in our mission to deliver world‑class scientific solutions and make a significant impact in the research community. Your expertise and ambition will be instrumental in helping us achieve outstanding results!

Additional Information ABOUT LGC

LGC is a leading, global life science tools company, providing mission‑critical components and solutions into high‑growth application areas across the human healthcare and applied market segments. Its high‑quality product portfolio is comprised of mission‑critical tools for genomic analysis and for quality assurance applications, which are typically embedded and recurring within our customers’ products and workflows and are valued for their performance, quality, and range.

OUR VALUES
  • PASSION
  • CURIOSITY
  • INTEGRITY
  • BRILLIANCE
  • RESPECT
EQUAL OPPORTUNITIES

LGC strongly believes that every job applicant and employee should be valued for their individual talents regardless of age, disability, race, colour, ethnic or national origin, sex, sexual orientation, gender reassignment, marital or civil partnership, pregnancy or maternity, religion, or belief. Short‑listing, interviewing and selection will always be carried out without regard to gender, sexual orientation, marital status, colour, race, nationality, ethnic or national origins, religion or belief, age, or trade union membership.

For more information about LGC, please visit our website

#scienceforasaferworld

Principal Scientist • Kidlington, OXFORDSHIRE, United Kingdom

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Principal Scientist, Inflammation Research

Oxford  £60,000 - £90,000 per year  help_outline Gilead Sciences, Inc.

Posted 8 days ago

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Job Description

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.
**Job Description**
We are seeking an experienced immunologist to lead a talented team of scientists supporting the development of novel biologic therapies in autoimmune disease. The successful candidate will conduct and oversee _in vitro_ and _in vivo_ pharmacology studies supporting both lead and early discovery programs in immunology, and will require rigour in delivering data packages for progression to development. They will collaborate across functions to pursue creative science, in the service of discovering novel medicines that impact patients' lives.
**Additional Key Responsibilities**
Leadership
+ Mentor a lab-based scientific team, advancing their projects and careers.
+ Serve as a scientific and technical thought leader throughout the Research organization.
+ Collaborate across functions to guide interdisciplinary projects, with experts in immunology, protein engineering, chemistry, translational medicine, biomarkers and clinical development. Identify project risks and mitigate effectively, while communicating with project teams and other leaders.
Innovation and Scientific Acumen
+ Proactively ideate to accelerate early-stage discovery activities, enhance understanding of disease mechanisms, and develop new technologies and novel targeting modalities.
+ Design and implement rigorous _in vitro_ assays, based on thorough literature review, to support the development of therapeutic antibodies in autoimmune disease
+ Work with internal teams and contract research organisations to plan and co-ordinate in vivo models for DMPK and efficacy
+ Develop endpoint analysis, including ex vivo profiling, to better understand drug mechanism of action
+ Develop expertise in relevant scientific fields and the external landscape, including the scientific literature, conference proceedings, and competitive programs. As an in-house expert, propose creative and rigorous research to discover, validate and understand targets.
+ Think critically and creatively, emphasizing nimble decision making that balances risk-taking with thoughtful experimentation within the strategic/competitive context to fuel a differentiated pre-clinical pipeline.
+ Contribute expertise to multi-disciplinary due diligence teams to evaluate and recommend partnerships and acquisitions.
+ Contribute to research reports, INDs, and patent filings.
+ Establish an external presence through peer-reviewed publications, conference presentations, and external collaborations.
**Knowledge, Experience and Skills**
+ PhD and 5+ years of experience (immunology, drug discovery, target identification and technology development), with industry experience highly preferred.
+ Strong track record of impact in scientific field, including first- or senior-author publications in peer-reviewed journals and conference presentations.
+ Strong knowledge base in basic immunology and pathogenesis of autoimmune disease
+ Broad technical skillset of cutting-edge methods and models of immunology, _in vitro_ and _in vivo_
+ Demonstrated success in leading research teams to productive, creative, data-driven decisions.
+ Team-centric mindset, with proven managerial excellence and ability to motivate skilled team members from diverse backgrounds.
+ Excellent communication and interpersonal skills.
**Equal Employment Opportunity (EEO)**
It is the policy of Gilead Sciences, Inc. and its subsidiaries and affiliates (collectively "Gilead" or the "Company") to recruit select and employ the most qualified persons available for positions throughout the Company. Except if otherwise provided by applicable law, all employment actions relating to issues such as compensation, benefits, transfers, layoffs, returns from layoffs, company-sponsored training, education assistance, social and recreational programs are administered on a non-discriminatory basis (i.e. without regard to protected characteristics or prohibited grounds, which may include an individual's gender, race, color, national origin, ancestry, religion, creed, physical or mental disability, marital status, sexual orientation, medical condition, veteran status, and age, unless such protection is prohibited by federal, state, municipal, provincial, local or other applicable laws). Gilead also prohibits discrimination based on any other characteristics protected by applicable laws.
**For Current Gilead Employees and Contractors:**
Please apply via the Internal Career Opportunities portal in Workday.
Gilead Sciences, Inc. is a biopharmaceutical company that has pursued and achieved breakthroughs in medicine for more than three decades, with the goal of creating a healthier world for all people. The company is committed to advancing innovative medicines to prevent and treat life-threatening diseases, including HIV, viral hepatitis and cancer. Gilead operates in more than 35 countries worldwide, with headquarters in Foster City, California.
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R&D Principal Scientist

Newcastle upon Tyne  £60,000 - £90,000 per year  help_outline Danaher Corporation

Posted 9 days ago

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Job Description

Bring more to life.
Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology?
At Leica Biosystems, one of Danaher's ( 15+ operating companies, our work saves lives-and we're all united by a shared commitment to innovate for tangible impact.
You'll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher's system of continuous improvement, you help turn ideas into impact - innovating at the speed of life.
At Leica Biosystems, we're not just shaping the future of cancer diagnostics - we're transforming lives. Our mission of "Advancing Cancer Diagnostics, Improving Lives" is the driving force behind everything we do. As a global leader with the most comprehensive portfolio spanning from biopsy to diagnosis, we empower clinicians with innovative, reliable solutions so they can give patients timely, accurate answers when they need them most. When you join Leica Biosystems, you're not just taking a job; you're becoming part of a passionate team that knows every moment matters when it comes to cancer. You'll help develop diagnostic solutions that turn anxiety into answers, and aid the acceleration of next-generation, life-changing therapies. Surrounded by a diverse and collaborative global community, you'll be inspired each day to stretch, grow, and make an impact.
Learn about the Danaher Business System ( which makes everything possible.
The R&D Principal Scientist is responsible for providing expertise regarding technical aspects of product development, current and future technologies and products on market. They may also be responsible for the people management of a team of up to 3 associates.
This position reports to the R&D Manager and is part of the R&D team located in Newcastle Upon Tyne and will be an on-site role.
In this role, you will have the opportunity to:
+ Be part of a winning R&D team, delivering projects through expertise in assay design and clinical expertise across multiple, complex R&D projects.
+ Apply scientific and customer insight into current and future strategy of assay and system development.
+ Build scientific and problem solving capability in others through ongoing self professional development and mentoring or managing others within the team.
The essential requirements of the job include:
+ Demonstrated expertise in scoring and interpretation of IHC (HER2 and Allred scoring desirable)
+ Significant experience in immunohistochemistry and in situ hybridisation, gained within a clinical or academic histopathology laboratory
+ Expert knowledge of cancer biology and clinically relevant biomarkers and diagnostic panels
It would be a plus if you also possess previous experience in:
+ End-to-end clinical histology laboratory workflows, including fixation, microtomy, staining, and interpretation
+ Leading or providing structured coaching, mentoring, or technical training to associates or peers
+ Antibody or diagnostic assay development in an academic, clinical, or industrial environment
+ Experience in digital and/or computational pathology methodologies and applications.
#LI-onsite
Join our winning team today. Together, we'll accelerate the real-life impact of tomorrow's science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.
For more information, visit .
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Principal Scientist

Cardiff  £60,000 - £90,000 per year  help_outline Talentmark

Posted 3 days ago

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Job Description

Talentmark are recruiting for a Principal Scientist to join a leading full-service CRO at their site based in South Wales on a permanent basis.

The Company

Our client is an established and expanding CRO that offer full-service clinical development solutions.

Location

This Principal Scientist role is located a commutable distance from Cardiff, Newport and surrounding areas.

Responsibilities
  • Degree in a scientific discipline or equivalent; advanced qualification desirable
  • Extensive experience using LC-MS/MS in a regulated laboratory environment (GCP, GLP, GMP)
  • Proven track record of leading LC-MS/MS‑based studies, including method development, validation, and routine sample analysis
  • Deep technical expertise in mass spectrometry
  • Strong understanding of bioanalytical method validation
  • Experience in reviewing and approving analytical data, reports, and study documentation
Qualifications / Background
  • MSc or PhD in a relevant discipline
  • Experience within a CRO or clinical trial environment
  • Knowledge of MHRA Phase I Accreditation scheme requirements
  • Experience in process improvement, operational efficiency, or workflow optimisation
Apply

It is essential that applicants hold entitlement to work in the UK. Please quote job reference (phone number removed) in all correspondence.

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Principal Scientist Immunoassay

Fordham  £60,000 - £90,000 per year  help_outline Resolian

Posted 1 day ago

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Job Description

This role is centred on providing scientific leadership and oversight of all the technical aspects within the local Fordham immunoassay group, and throughout the wider Resolian immunoassay teams.

You will be responsible for providing supervision, guidance, and expertise, in order to facilitate the delivery of high quality methods and sample analysis results to our customers in compliance with GLP/GCP.

As a Principal Scientist, you are an expert in scientific technology and experimental practice with peer recognition and credibility. You have a track record of publications and presentations in support of this, which you proactively drive.

Principal Scientists should lead from the lab. They are capable of working creatively and autonomously and they possess a deep technical understanding to develop or troubleshoot methods themselves across all service areas. They demonstrate scientific leadership and clear decision making, directing the work of more junior staff, leading technical training and promotion of good scientific practices.

Responsibilities

We are looking for someone who has an innate ability to adopt and adapt new technology and can be an active contributor to the company’s Scientific Strategy. You will also be creative, innovative, agile and collegiate. This means they also promote scientific collaboration, knowledge sharing, and best practice across all Resolian sites; they often explore opportunities to create new service lines or scientific IP, and they can possess expertise that cuts across multiple departments.

Principal Scientists are highly visible and outward interfacing, they are the scientific facade of Resolian, and they use their skills and expertise to advise customers and drive new business.

Confidence in regular effective external communication is expected, as is deputising for senior management. This also includes assisting with presentations to new customers and participation in global capability meetings, and directing technical input for new RFP/RFIs. Externally, they will build a professional reputation at both personal and corporate levels, through regular podium presentations at key bioanalytical conferences. They are always forward-looking, and ready to be vocal to challenge the status quo if they see a better solution.

What will I be doing?
  • Provide oversight of active method development projects in the Immunoassay Bioanalysis group, ensure projects are progressing to client expectations
  • Lead challenging method development projects, using expert knowledge to deliver quality methods on-time
  • Drive the method development strategy, ensuring methods are developed efficiently, and are robust, fit-for-purpose and compliant. Defend these decisions under regulatory scrutiny.
  • Mentor scientists working on method development projects; providing scientific guidance and support
  • Provide troubleshooting expertise across multiple methods and platforms
  • Review and interpret method trending data and drive improvements as appropriate
  • Review method establishment and method validation data ensuring methods are of good quality before they progress to the next stage
  • Deliver scientific training within the group and present internally on best practices
  • Have a good knowledge of the appropriate GLP / GCP standards and latest regulatory guidelines and industry thought leaders.
  • Provide scientific support to the Business Development team; review customer requests and advise on feasibility
  • Contribute to a culture of continuous improvement
  • Build and maintain good working relationships with internal and external clients, management and other scientific staff
  • Familiarity with the financial aspects of projects including time and materials costs
Skills, Education & Qualifications
  • Degree in pharmaceutical sciences, biochemistry, chemistry, biological sciences, or equivalent industry experience in bioanalysis.
  • Extensive experience leading the development, validation, and application of ligand-binding assays to support PK, biomarker, and immunogenicity (ADA and NAb) studies across preclinical and clinical programmes.
  • Strong scientific judgement in selecting fit-for-purpose bioanalytical platforms to meet sponsor requirements and regulatory expectations.
  • Proven experience operating within a GxP-regulated CRO environment.
  • In-depth knowledge of global regulatory guidance and industry best practice for bioanalytical method validation of PK, biomarker, and immunogenicity assays.
  • Demonstrated scientific leadership, including mentoring scientists, setting bioanalytical strategy, and collaborating effectively with cross-functional teams.

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Principal Scientist Immunoassay

Fordham  £60,000 - £90,000 per year  help_outline Kids for the Future

Posted 1 day ago

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Job Description

  • Location Newmarket Road,Fordham, CB75WW,United Kingdom
  • Employee Type Regular Full Time
  • Name Heather Triolo
Description

We are looking for someone who has an innate ability to adopt and adapt new technology and can be an active contributor to the company’s Scientific Strategy. You will also be creative, innovative, agile and collegiate. This means they also promote scientific collaboration, knowledge sharing, and best practice across all Resolian sites; they often explore opportunities to create new service lines or scientific IP, and they can possess expertise that cuts across multiple departments.

Principal Scientists are highly visible and outward interfacing, they are the scientific facade of Resolian, and they use their skills and expertise to advise customers and drive new business. Confidence in regular effective external communication is expected, as is deputising for senior management. This also includes assisting with presentations to new customers and participation in global capability meetings, and directing technical input for new RFP/RFIs. Externally, they will build a professional reputation at both personal and corporate levels, through regular podium presentations at key bioanalytical conferences. They are always forward‑looking, and ready to be vocal to challenge the status quo if they see a better solution.

What will I be doing?
  • Provide oversight of active method development projects in the Immunoassay Bioanalysis group, ensure projects are progressing to client expectations
  • Lead challenging method development projects, using expert knowledge to deliver quality methods on-time
  • Drive the method development strategy, ensuring methods are developed efficiently, and are robust, fit‑for‑purpose and compliant. Defend these decisions under regulatory scrutiny
  • Mentor scientists working on method development projects; providing scientific guidance and support
  • Provide troubleshooting expertise across multiple methods and platforms
  • Review and interpret method trending data and drive improvements as appropriate
  • Review method establishment and method validation data ensuring methods are of good quality before they progress to the next stage
  • Deliver scientific training within the group and present internally on best practices
  • Have a good knowledge of the appropriate GLP / GCP standards and latest regulatory guidelines and industry thought leaders
  • Provide scientific support to the Business Development team; review customer requests and advise on feasibility
  • Contribute to a culture of continuous improvement
  • Build and maintain good working relationships with internal and external clients, management and other scientific staff
  • Familiarity with the financial aspects of projects including time and materials costs
Requirements
  • Degree in pharmaceutical sciences, biochemistry, chemistry, biological sciences, or equivalent industry experience in bioanalysis
  • Extensive experience leading the development, validation, and application of ligand‑binding assays to support PK, biomarker, and immunogenicity (ADA and NAb) studies across preclinical and clinical programmes
  • Strong scientific judgement in selecting fit‑for‑purpose bioanalytical platforms to meet sponsor requirements and regulatory expectations
  • Proven experience operating within a GxP‑regulated CRO environment
  • In‑depth knowledge of global regulatory guidance and industry best practice for bioanalytical method validation of PK, biomarker, and immunogenicity assays
  • Demonstrated scientific leadership, including mentoring scientists, setting bioanalytical strategy, and collaborating effectively with cross‑functional teams
Summary

This role is centred on providing scientific leadership and oversight of all the technical aspects within the local Fordham immunoassay group, and throughout the wider Resolian immunoassay teams.

You will be responsible for providing supervision, guidance, and expertise, in order to facilitate the delivery of high quality methods and sample analysis results to our customers in compliance with GLP/GCP.

As a Principal Scientist, you are an expert in scientific technology and experimental practice with peer recognition and credibility. You have a track record of publications and presentations in support of this, which you proactively drive.

Principal Scientists should lead from the lab. They are capable of working creatively and autonomously and they possess a deep technical understanding to develop or troubleshoot methods themselves across all service areas. They demonstrate scientific leadership and clear decision making, directing the work of more junior staff, leading technical training and promotion of good scientific practices.

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Principal Scientist

Bedford  £60,000 - £90,000 per year  help_outline Werfen

Posted 4 days ago

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Job Description

Overview: Fully competent in one or more scientific/technical areas. Plans and conducts scientific assignments requiring mastery of specialized techniques.

Responsibilities

Key Accountabilities

Essential Functions:

  • Applies scientific method and experimental design in problem solving.
  • Uses scientific expertise to provide solutions to a broad range of difficult problems.
  • Solutions are original, thorough and practical.
  • Frequently communicates progress status to supervisor.
  • Performs complicated or demanding assignments requiring specialized knowledge.
  • May offer solutions that are creative and/or inventive.
  • Defines short and mid-term objectives and implements plan to accomplish objectives.
  • May direct the work of other personnel.
  • Maintains accurate, precise, and legible laboratory notebooks.
  • Frequently communicates status updates across the organization.
  • Maintains good documentation.
  • Writes reports and technical summaries.
  • May represent company to outside organizations.
  • Continually broadens professional expertise through comprehensive knowledge of scientific literature and competitive products.
  • Handles broad assignments and objectives under minimum supervision.
  • Accomplishes short-term objectives.
  • Performs other related duties as assigned.

Budget Managed (if applicable):

  • N/A

Internal Networking/Key Relationships:

  • To be determined based on department needs

Skills & Capabilities:

  • Must demonstrate the ability to perform all duties and responsibilities at the Scientist II level
  • Functional/technical skills

Qualifications

Minimum Knowledge & Experience Required for the Position:

  • Duties require broad use and application of scientific principles, theories and concepts in field of expertise. This may be acquired through completion of a Ph.D. degree in a scientific discipline, or equivalent.
  • Professional experience is preferred.

International Mobility: Required:

  • No

Travel Requirements:

  • <5% of time

Note: Salary information is not disclosed in this posting.

This role is eligible for medical, dental, and vision insurance, k plan retirement benefits with an employer match, as well as paid vacation and sick leave. Our sales roles are eligible for participation in a commission plan and our management, and select professional roles, are eligible for a performance-based bonus.

We are an Equal Opportunity employer and are committed to a diverse workplace. Werfen strictly prohibits unlawful discrimination, harassment or retaliation based upon an individual’s race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other protected characteristic as defined by applicable state or federal law. If you have a disability and need an accommodation in relation to the online application process, please contact for assistance.

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